메뉴 건너뛰기




Volumn , Issue , 2009, Pages 121-148

Multidrug resistance in solid tumor and its reversal

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84864769484     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4419-0131-6_4     Document Type: Chapter
Times cited : (10)

References (148)
  • 2
    • 33749073242 scopus 로고    scopus 로고
    • An anniversary for cancer chemotherapy
    • Hirsch J. An anniversary for cancer chemotherapy. JAMA 2006;296:1518-1520.
    • (2006) JAMA , vol.296 , pp. 1518-1520
    • Hirsch, J.1
  • 3
    • 15944378053 scopus 로고    scopus 로고
    • Principles of cancer chemotherapy
    • Vokes EE, GolombHM ed, Springer, New York
    • Ewesuedo RB, Ratain MJ. Principles of cancer chemotherapy. In: Vokes EE, GolombHM (ed). Oncologic Therapies. Springer, New York. 2003; pp. 19-67.
    • (2003) Oncologic Therapies , pp. 19-67
    • Ewesuedo, R.B.1    Ratain, M.J.2
  • 4
    • 0242331206 scopus 로고    scopus 로고
    • Drug resistance reversal - Are we getting closer
    • Baird RD, Kaye SB. Drug resistance reversal - are we getting closer. Eur J Cancer 2003;39:2450-2461.
    • (2003) Eur J Cancer , vol.39 , pp. 2450-2461
    • Baird, R.D.1    Kaye, S.B.2
  • 5
    • 27644549557 scopus 로고    scopus 로고
    • Recent advances on the molecular mechanisms involved in pancreatic cancer progression and therapies
    • Mimeault M, Brand RE, Sasson AA, Batra SK. Recent advances on the molecular mechanisms involved in pancreatic cancer progression and therapies. Pancreas 2005;31:301-316.
    • (2005) Pancreas , vol.31 , pp. 301-316
    • Mimeault, M.1    Brand, R.E.2    Sasson, A.A.3    Batra, S.K.4
  • 6
    • 29844443964 scopus 로고    scopus 로고
    • Recent advances on multiple tumorigenic cascades involved in prostatic cancer progress and targeting therapies
    • Mimeault M, Batra SK. Recent advances on multiple tumorigenic cascades involved in prostatic cancer progress and targeting therapies. Carcinogenesis 2006;24:1-22.
    • (2006) Carcinogenesis , vol.24 , pp. 1-22
    • Mimeault, M.1    Batra, S.K.2
  • 8
    • 0142029122 scopus 로고    scopus 로고
    • Resistance mechanisms of gastrointestinal cancers: Why does conventional chemotherapy fail?
    • Gieseler F, Rudolph P, Kloeppel G, Foelsch UR. Resistance mechanisms of gastrointestinal cancers: why does conventional chemotherapy fail? Int J Colorectal Disease 2003;18:470-480.
    • (2003) Int J Colorectal Disease , vol.18 , pp. 470-480
    • Gieseler, F.1    Rudolph, P.2    Kloeppel, G.3    Foelsch, U.R.4
  • 9
    • 33750722426 scopus 로고    scopus 로고
    • Cancer treatment and chemotherapy
    • DiPiro JT, Talbert RL, Yee GC et al. ed, McGraw-Hill, New York
    • Balmer CM, Valley AW, Iannucci A. Cancer treatment and chemotherapy. In: DiPiro JT, Talbert RL, Yee GC et al. (ed). Pharmacotherapy: A Pathophysiologic Approach. McGraw-Hill, New York, 2005; pp. 2279-2328.
    • (2005) Pharmacotherapy: A Pathophysiologic Approach , pp. 2279-2328
    • Balmer, C.M.1    Valley, A.W.2    Iannucci, A.3
  • 11
  • 12
    • 0014767029 scopus 로고
    • Cellular resistance to actinomycin D in Chinese hamster cells in vitro: Cross-resistance, radioautographic, and cytogenic studies
    • Biedler JL, Riehm H. Cellular resistance to actinomycin D in Chinese hamster cells in vitro: cross-resistance, radioautographic, and cytogenic studies. Cancer Res 1970;30:1174-1184.
    • (1970) Cancer Res , vol.30 , pp. 1174-1184
    • Biedler, J.L.1    Riehm, H.2
  • 13
    • 33645830172 scopus 로고
    • A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
    • Juliano RL, Ling V. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim Acta 1976;455:152-162.
    • (1976) Biochim Acta , vol.455 , pp. 152-162
    • Juliano, R.L.1    Ling, V.2
  • 14
    • 2542491777 scopus 로고    scopus 로고
    • The role of ABC transporters in drug resistance, metabolism and toxicity
    • Glavinas H, Krajcsi P, Cserepes J, Sarkadi B. The role of ABC transporters in drug resistance, metabolism and toxicity. Curr Drug Deliv 2004;1:27-42.
    • (2004) Curr Drug Deliv , vol.1 , pp. 27-42
    • Glavinas, H.1    Krajcsi, P.2    Cserepes, J.3    Sarkadi, B.4
  • 15
    • 0018566696 scopus 로고
    • Purification of P-glycoprotein from plasma membrane vesicles of Chinese hamster ovary cell mutants with reduced colchicine permeability
    • Riordan JR, Ling V. Purification of P-glycoprotein from plasma membrane vesicles of Chinese hamster ovary cell mutants with reduced colchicine permeability. J Biol Chem 1979;254:12701-12705.
    • (1979) J Biol Chem , vol.254 , pp. 12701-12705
    • Riordan, J.R.1    Ling, V.2
  • 16
    • 0021797892 scopus 로고
    • Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines
    • Riordan JR, Deuchars KK, Norbert AN, Noa A, Jeffrey T, Ling V. Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines. Nature 1985;316:817-819.
    • (1985) Nature , vol.316 , pp. 817-819
    • Riordan, J.R.1    Deuchars, K.K.2    Norbert, A.N.3    Noa, A.4    Jeffrey, T.5    Ling, V.6
  • 17
    • 0019964180 scopus 로고
    • DNA-mediated transfer of multiple drug resistance and plasma membrane glycoprotein expression
    • Debenham PG, Kartner N, Siminovitch L, Riordan JR, Ling V. DNA-mediated transfer of multiple drug resistance and plasma membrane glycoprotein expression. Mol Cell Biol 1982;2:881-889.
    • (1982) Mol Cell Biol , vol.2 , pp. 881-889
    • Debenham, P.G.1    Kartner, N.2    Siminovitch, L.3    Riordan, J.R.4    Ling, V.5
  • 19
    • 0345688604 scopus 로고    scopus 로고
    • Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)
    • Doyle LA, Ross DD. Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2). Oncogene 2003;22:7340-7358.
    • (2003) Oncogene , vol.22 , pp. 7340-7358
    • Doyle, L.A.1    Ross, D.D.2
  • 20
    • 43449133278 scopus 로고    scopus 로고
    • Resistance to chemotherapy in cancer: A complex and integrated cellular response
    • Mellor HR, Callaghan R. Resistance to chemotherapy in cancer: A complex and integrated cellular response. Pharmacology 2008;81:275-300.
    • (2008) Pharmacology , vol.81 , pp. 275-300
    • Mellor, H.R.1    Callaghan, R.2
  • 21
    • 41849106072 scopus 로고    scopus 로고
    • Cellular mechanisms of resistance to anthracyclines and taxanes in cancer: Intrinsic and acquired
    • Chien AJ, Moasser MM. Cellular mechanisms of resistance to anthracyclines and taxanes in cancer: Intrinsic and acquired. Semin Oncol 2008;35:S1-S14.
    • (2008) Semin Oncol , vol.35
    • Chien, A.J.1    Moasser, M.M.2
  • 22
    • 42449161959 scopus 로고    scopus 로고
    • Recent advances on the molecular mechanisms involved in the drug resistance of cancer cells and novel targeting therapies
    • Mimeault M, Hauke R, Batra SK. Recent advances on the molecular mechanisms involved in the drug resistance of cancer cells and novel targeting therapies. Clin Pharmacol Therapeutics 2008;83:673-691.
    • (2008) Clin Pharmacol Therapeutics , vol.83 , pp. 673-691
    • Mimeault, M.1    Hauke, R.2    Batra, S.K.3
  • 23
    • 0037358040 scopus 로고    scopus 로고
    • Overcoming multidrug resistance in cancer: An update on the clinical strategy of inhibiting P-glycoprotein
    • Thomas H, Coley HM. Overcoming multidrug resistance in cancer: an update on the clinical strategy of inhibiting P-glycoprotein. Cancer Control 2003;10:159-165.
    • (2003) Cancer Control , vol.10 , pp. 159-165
    • Thomas, H.1    Coley, H.M.2
  • 24
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman MM, Fojo T, Bates SE. Multidrug resistance in cancer: role of ATP-dependent transporters. Natl Rev Cancer 2003;2:48-58.
    • (2003) Natl Rev Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 25
    • 0034917716 scopus 로고    scopus 로고
    • The human ATP-binding cassette (ABC) transporter superfamily
    • Dean M, Rzhetsky A, Allikmets R. The human ATP-binding cassette (ABC) transporter superfamily. Genome Res 2001;11:1156-1166.
    • (2001) Genome Res , vol.11 , pp. 1156-1166
    • Dean, M.1    Rzhetsky, A.2    Allikmets, R.3
  • 26
    • 0004342789 scopus 로고    scopus 로고
    • The human ATP-binding cassette (ABC) transporter superfamily
    • Accessed 4 October 2008
    • Dean M. The human ATP-binding cassette (ABC) transporter superfamily. National Library of Medicine (US), NCBI. http://www.ncbi.nlm.nih.gov/bookshelf/ br.fcgi? book=mono-001&part=A137. 2002, Accessed 4 October 2008.
    • (2002) National Library of Medicine (US), NCBI
    • Dean, M.1
  • 27
    • 33947154878 scopus 로고    scopus 로고
    • Structure of an ABC transporter in complex with its binding protein
    • Hollenstein K, Frei DC, Locher KP. Structure of an ABC transporter in complex with its binding protein. Nature 2007;446:213-216.
    • (2007) Nature , vol.446 , pp. 213-216
    • Hollenstein, K.1    Frei, D.C.2    Locher, K.P.3
  • 28
    • 35648963623 scopus 로고    scopus 로고
    • ABC transporters: How small machines do a big job
    • Davidson AL, Maloney PC. ABC transporters: how small machines do a big job. Trends Microbiol 2007;15:448-455.
    • (2007) Trends Microbiol , vol.15 , pp. 448-455
    • Davidson, A.L.1    Maloney, P.C.2
  • 29
    • 33745286306 scopus 로고    scopus 로고
    • Functional validation of the genetic polymorphisms of human ATP-binding cassette (ABC) transporter ABCG2: Identification of alleles that are defective in porphyrin transport
    • Tamura A, Watanabe M, Saito H, Nakagawa H, Kamachi T, Okura I, Ishikawa T. Functional validation of the genetic polymorphisms of human ATP-binding cassette (ABC) transporter ABCG2: identification of alleles that are defective in porphyrin transport. Mol Pharmacol 2006;70:287-296.
    • (2006) Mol Pharmacol , vol.70 , pp. 287-296
    • Tamura, A.1    Watanabe, M.2    Saito, H.3    Nakagawa, H.4    Kamachi, T.5    Okura, I.6    Ishikawa, T.7
  • 30
    • 0037131893 scopus 로고    scopus 로고
    • The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans
    • Fromm MF. The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans. Adv Drug Deliv Rev 2003;54:1295-1310.
    • (2003) Adv Drug Deliv Rev , vol.54 , pp. 1295-1310
    • Fromm, M.F.1
  • 31
    • 0036176510 scopus 로고    scopus 로고
    • Mechanisms of cancer drug resistance
    • Gottesman MM. Mechanisms of cancer drug resistance. Ann Rev Med 2002;53:615-627.
    • (2002) Ann Rev Med , vol.53 , pp. 615-627
    • Gottesman, M.M.1
  • 34
    • 22544457473 scopus 로고    scopus 로고
    • The reconstituted P-glycoproteinmultidrug transporter is a flippase for glucosylceramide and other simple glycosphingolipids
    • Eckford PD, Sharom FJ. The reconstituted P-glycoproteinmultidrug transporter is a flippase for glucosylceramide and other simple glycosphingolipids. Biochem J 2005;389:517-526.
    • (2005) Biochem J , vol.389 , pp. 517-526
    • Eckford, P.D.1    Sharom, F.J.2
  • 35
    • 33646596002 scopus 로고    scopus 로고
    • The remarkable transport mechanism of P-glycoprotein: A multidrug transporter
    • Al-Shawi MK, Omote H. The remarkable transport mechanism of P-glycoprotein: a multidrug transporter. J Bioenerg Biomembr 2006;37:489-496.
    • (2006) J Bioenerg Biomembr , vol.37 , pp. 489-496
    • Al-Shawi, M.K.1    Omote, H.2
  • 36
    • 33744483102 scopus 로고    scopus 로고
    • P-glycoprotein and 'lipid rafts': Some ambiguous mutual relationships (floating on them, building them or meeting them by chance?)
    • Orlowski S, Martin S, Escargueil A. P-glycoprotein and 'lipid rafts': some ambiguous mutual relationships (floating on them, building them or meeting them by chance?) Cell Mol Life Sci 2006;63:1038-1059.
    • (2006) Cell Mol Life Sci , vol.63 , pp. 1038-1059
    • Orlowski, S.1    Martin, S.2    Escargueil, A.3
  • 37
    • 0033799839 scopus 로고    scopus 로고
    • Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs
    • Krishna R, Mayer LD. Multidrug resistance (MDR) in cancer. mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs. Eur J Pharm Sci 2000;11:265-283.
    • (2000) Eur J Pharm Sci , vol.11 , pp. 265-283
    • Krishna, R.1    Mayer, L.D.2
  • 38
    • 35748977617 scopus 로고    scopus 로고
    • Challenges for blood-brain barrier (BBB) screening
    • Jeffrey P, Summerfield SG. Challenges for blood-brain barrier (BBB) screening. Xenobiotica 2007;37:1135-1151.
    • (2007) Xenobiotica , vol.37 , pp. 1135-1151
    • Jeffrey, P.1    Summerfield, S.G.2
  • 39
    • 33748743456 scopus 로고    scopus 로고
    • Transport of glyburide by placental ABC transporters: Implications in fetal drug exposure
    • Gedeon C, Behravan J, Koren G, Piquette-Miller M. Transport of glyburide by placental ABC transporters: implications in fetal drug exposure. Placenta 2006;27:1096-1010.
    • (2006) Placenta , vol.27 , pp. 1096-1010
    • Gedeon, C.1    Behravan, J.2    Koren, G.3    Piquette-Miller, M.4
  • 40
    • 0036892223 scopus 로고    scopus 로고
    • Multidrug resistance genes and P-glycoprotein in the testis of the rat, mouse, guinea pig, and human
    • Melaine N, Liénard M, Dorval I, Le Goascogne C, Lejeune H, Jégou B. Multidrug resistance genes and P-glycoprotein in the testis of the rat, mouse, guinea pig, and human. Biol Reprod 2002;67:1699-1707.
    • (2002) Biol Reprod , vol.67 , pp. 1699-1707
    • Melaine, N.1    Liénard, M.2    Dorval, I.3    Le Goascogne, C.4    Lejeune, H.5    Jégou, B.6
  • 41
    • 0034254733 scopus 로고    scopus 로고
    • Enforced P-glycoprotein pump function in murine bone marrow cells results in expansion of side population stem cells in vitro and repopulating cells in vivo
    • Bunting KD, Zhou S, Lu T, Brian P. Enforced P-glycoprotein pump function in murine bone marrow cells results in expansion of side population stem cells in vitro and repopulating cells in vivo. Blood 2000;96:902-909.
    • (2000) Blood , vol.96 , pp. 902-909
    • Bunting, K.D.1    Zhou, S.2    Lu, T.3    Brian, P.4
  • 42
    • 0033958086 scopus 로고    scopus 로고
    • Multiple physiological functions for multidrug transporter P-glycoprotein
    • Johnstone RW, Ruefli AA, Smyth MJ. Multiple physiological functions for multidrug transporter P-glycoprotein. Tr Biochem Sci 2000;25:1-6.
    • (2000) Tr Biochem Sci , vol.25 , pp. 1-6
    • Johnstone, R.W.1    Ruefli, A.A.2    Smyth, M.J.3
  • 43
    • 2042451616 scopus 로고    scopus 로고
    • Cellular localization and functional expression of P-glycoprotein in rat astrocyte cultures
    • Ronaldson PT, Bendayan M, Gingras D, Piquette-Miller M, Bendayan R. Cellular localization and functional expression of P-glycoprotein in rat astrocyte cultures. J Neurochem 2004;89:788-800.
    • (2004) J Neurochem , vol.89 , pp. 788-800
    • Ronaldson, P.T.1    Bendayan, M.2    Gingras, D.3    Piquette-Miller, M.4    Bendayan, R.5
  • 44
    • 34547500470 scopus 로고    scopus 로고
    • Localization of P-glycoprotein at the nuclear envelope of rat brain cells
    • Babakhanian K, Bendayan M, Bendayan R. Localization of P-glycoprotein at the nuclear envelope of rat brain cells. Biochem Biophys Res Commun 2007;361:301-306.
    • (2007) Biochem Biophys Res Commun , vol.361 , pp. 301-306
    • Babakhanian, K.1    Bendayan, M.2    Bendayan, R.3
  • 45
    • 0034667390 scopus 로고    scopus 로고
    • Extensive contribution of the multidrug transporters P-glycoprotein and Mrp1 to basal drug resistance
    • Allen JD, Brinkhuis RF, van Deemter L, Wijnholds J, Schinkel AH. Extensive contribution of the multidrug transporters P-glycoprotein and Mrp1 to basal drug resistance. Cancer Res 2000;60:5761-5766.
    • (2000) Cancer Res , vol.60 , pp. 5761-5766
    • Allen, J.D.1    Brinkhuis, R.F.2    Van Deemter, L.3    Wijnholds, J.4    Schinkel, A.H.5
  • 46
    • 0030050691 scopus 로고    scopus 로고
    • MDA435/LCC6/WT and MDA435/LCC6/mdr1: Ascites models of human breast cancer
    • Leonessa F, Green D, Licht T, Wijinholds J, Schinkel AH. MDA435/LCC6/WT and MDA435/LCC6/mdr1: ascites models of human breast cancer. Br J Cancer 1996;73:154-161.
    • (1996) Br J Cancer , vol.73 , pp. 154-161
    • Leonessa, F.1    Green, D.2    Licht, T.3    Wijinholds, J.4    Schinkel, A.H.5
  • 47
    • 0033836109 scopus 로고    scopus 로고
    • Can multidrug resistance mechanisms be modified?
    • Arceci RJ. Can multidrug resistance mechanisms be modified? Brit J Haematol 2000;110:285-291.
    • (2000) Brit J Haematol , vol.110 , pp. 285-291
    • Arceci, R.J.1
  • 48
    • 0024329881 scopus 로고
    • The biochemistry of P-glycoprotein-mediated multidrug resistance
    • Endicott JA, Ling V. The biochemistry of P-glycoprotein-mediated multidrug resistance. Ann Rev Biochem 1989;58:137-171.
    • (1989) Ann Rev Biochem , vol.58 , pp. 137-171
    • Endicott, J.A.1    Ling, V.2
  • 49
    • 0036815092 scopus 로고    scopus 로고
    • P-glycoprotein-mediated efflux as a major factor in the variance of absorption and distribution of drugs: Modulation of chemotherapy resistance
    • Johnson WW. P-glycoprotein-mediated efflux as a major factor in the variance of absorption and distribution of drugs: modulation of chemotherapy resistance. Methods Find Exp Clin Pharmacol 2002;24:501-514.
    • (2002) Methods Find Exp Clin Pharmacol , vol.24 , pp. 501-514
    • Johnson, W.W.1
  • 50
    • 0034854749 scopus 로고    scopus 로고
    • Induction of chemoresistance in HL-60 cells concomitantly causes a resistance to apoptosis and the synthesis of P-glycoprotein
    • Campone M, Vavasseur F, Le Cabellec MT, Meflah K, Vallette FM, Oliver L. Induction of chemoresistance in HL-60 cells concomitantly causes a resistance to apoptosis and the synthesis of P-glycoprotein. Leukemia 2001;15:1377-1387.
    • (2001) Leukemia , vol.15 , pp. 1377-1387
    • Campone, M.1    Vavasseur, F.2    Le Cabellec, M.T.3    Meflah, K.4    Vallette, F.M.5    Oliver, L.6
  • 51
    • 0033074376 scopus 로고    scopus 로고
    • A multidrug-resistant breast cancer line induced by weekly exposure to doxorubicin
    • Hahn SM, Russo A, Cook JA, Mitchell JB. A multidrug-resistant breast cancer line induced by weekly exposure to doxorubicin. Int J Oncol 1999;14:273-279.
    • (1999) Int J Oncol , vol.14 , pp. 273-279
    • Hahn, S.M.1    Russo, A.2    Cook, J.A.3    Mitchell, J.B.4
  • 52
    • 0029133131 scopus 로고
    • Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes
    • Mayer R, Kartenbeck J, Buchler M, Jedlitschky G, Leier I, Keppler D. Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes. J Cell Biol 1995;131:137-150.
    • (1995) J Cell Biol , vol.131 , pp. 137-150
    • Mayer, R.1    Kartenbeck, J.2    Buchler, M.3    Jedlitschky, G.4    Leier, I.5    Keppler, D.6
  • 54
    • 13044249156 scopus 로고    scopus 로고
    • A multidrug resistance transporter from human MCF-7 breast cancer cells
    • Doyle LA, Yang W, Abruzzo LV. A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci USA 1998;95:15665-15670.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15665-15670
    • Doyle, L.A.1    Yang, W.2    Abruzzo, L.V.3
  • 56
    • 0036772386 scopus 로고    scopus 로고
    • Frequent expression of the multi-drug resistance-associated protein BCRP/MXR/ABCP/ABCG2 in human tumours detected by the BXP-21 monoclonal antibody in paraffin-embedded material
    • Diestra JE, Scheffer GL, Catala II, Maliepaard M, Schellens JH, Scheper RJ, Germà-Lluch JR, Izquierdo MA. Frequent expression of the multi-drug resistance-associated protein BCRP/MXR/ABCP/ABCG2 in human tumours detected by the BXP-21 monoclonal antibody in paraffin-embedded material. J Pathol 2002;198:213-219.
    • (2002) J Pathol , vol.198 , pp. 213-219
    • Diestra, J.E.1    Scheffer, G.L.2    Catala, I.I.3    Maliepaard, M.4    Schellens, J.H.5    Scheper, R.J.6    Germà-Lluch, J.R.7    Izquierdo, M.A.8
  • 57
    • 0033429542 scopus 로고    scopus 로고
    • Camptothecin resistance: Role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells
    • Brangi M, Litman T, Ciotti M, Nishiyama K, Kohlhagen G, Takimoto C, Robey R, Pommier Y, Fojo T, Bates SE. Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells. Cancer Res 1999;59:5938-5946.
    • (1999) Cancer Res , vol.59 , pp. 5938-5946
    • Brangi, M.1    Litman, T.2    Ciotti, M.3    Nishiyama, K.4    Kohlhagen, G.5    Takimoto, C.6    Robey, R.7    Pommier, Y.8    Fojo, T.9    Bates, S.E.10
  • 61
    • 25844443754 scopus 로고    scopus 로고
    • Breast cancer resistance protein: Molecular target for anticancer drug resistance and pharmacokinetics/pharmacodynamics
    • Sugimoto Y, Tsukahara S, Ishikawa E, Mitsuhashi J. Breast cancer resistance protein: molecular target for anticancer drug resistance and pharmacokinetics/pharmacodynamics. Cancer Sci 2005;96:457-465.
    • (2005) Cancer Sci , vol.96 , pp. 457-465
    • Sugimoto, Y.1    Tsukahara, S.2    Ishikawa, E.3    Mitsuhashi, J.4
  • 63
    • 33750349856 scopus 로고    scopus 로고
    • The ATP-binding cassette transporter ABCA2 as a mediator of intracellular trafficking
    • Mack JT, Beljanski V, Tew KD, Townsend DM. The ATP-binding cassette transporter ABCA2 as a mediator of intracellular trafficking. Biomed Pharmacother 2006;60:587-592.
    • (2006) Biomed Pharmacother , vol.60 , pp. 587-592
    • Mack, J.T.1    Beljanski, V.2    Tew, K.D.3    Townsend, D.M.4
  • 66
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • Dean M, Fojo T, Bates S. Tumour stem cells and drug resistance. Nat Rev Cancer 2005;5:275-284.
    • (2005) Nat Rev Cancer , vol.5 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 67
    • 0030800078 scopus 로고    scopus 로고
    • Quantitative structure-activity relationship of multidrug resistance reversal agents
    • Klopman G, Shi LM, Ramu A. Quantitative structure-activity relationship of multidrug resistance reversal agents. Mol Pharmacol 1997;52:323-334.
    • (1997) Mol Pharmacol , vol.52 , pp. 323-334
    • Klopman, G.1    Shi, L.M.2    Ramu, A.3
  • 70
  • 72
    • 0033052443 scopus 로고    scopus 로고
    • Selective inhibition of MDR1 P-glycoproteinmediated transport by the acridone carboxamide derivative GG918
    • Wallstab A, Koester M, Bohme M, Keppler D. Selective inhibition of MDR1 P-glycoproteinmediated transport by the acridone carboxamide derivative GG918. Br J Cancer 1999;79:1053-1060.
    • (1999) Br J Cancer , vol.79 , pp. 1053-1060
    • Wallstab, A.1    Koester, M.2    Bohme, M.3    Keppler, D.4
  • 73
    • 0034092081 scopus 로고    scopus 로고
    • Incidence of P-glycoprotein over expression and multidrug resistance (MDR) reversal in adult soft tissue sarcoma
    • Coley HM, Verrill MW, Gregson SE. Incidence of P-glycoprotein over expression and multidrug resistance (MDR) reversal in adult soft tissue sarcoma. Eur J Cancer 2000;36:881-888.
    • (2000) Eur J Cancer , vol.36 , pp. 881-888
    • Coley, H.M.1    Verrill, M.W.2    Gregson, S.E.3
  • 78
    • 0345084436 scopus 로고    scopus 로고
    • The multidrug resistance modulator valspodar (PSC 833) is metabolized by human cytochrome P450 3A: Implications for drug-drug interactions and pharmacological activity of the main metabolite
    • Fischer V, Rodriguez-Gascon A, Heitz F, Tynes R, Hauck C, Cohen D, Vickers AEM. The multidrug resistance modulator valspodar (PSC 833) is metabolized by human cytochrome P450 3A: Implications for drug-drug interactions and pharmacological activity of the main metabolite. Drug Metab Dispos 1998;26:802-811.
    • (1998) Drug Metab Dispos , vol.26 , pp. 802-811
    • Fischer, V.1    Rodriguez-Gascon, A.2    Heitz, F.3    Tynes, R.4    Hauck, C.5    Cohen, D.6    Vickers, A.E.M.7
  • 80
    • 33745746815 scopus 로고    scopus 로고
    • Pharmacological strategies for overcoming multidrug resistance
    • Nobili S, Landini I, Giglioni B, Mini E. Pharmacological strategies for overcoming multidrug resistance. Current Drug Targets 2006;7:861-879.
    • (2006) Current Drug Targets , vol.7 , pp. 861-879
    • Nobili, S.1    Landini, I.2    Giglioni, B.3    Mini, E.4
  • 81
    • 0010039537 scopus 로고    scopus 로고
    • What does Multidrug Resistance (MDR) Expression Mean in the Clinic?
    • Duhem C, Ries F, Dicato M. What does Multidrug Resistance (MDR) Expression Mean in the Clinic? The Oncologist 1996;1:151-158.
    • (1996) The Oncologist , vol.1 , pp. 151-158
    • Duhem, C.1    Ries, F.2    Dicato, M.3
  • 85
    • 0033628853 scopus 로고    scopus 로고
    • Cellular mechanisms of multidrug resistance of tumor cells
    • Stavrovskaya AA. Cellular mechanisms of multidrug resistance of tumor cells. Biochemistry 2000;65:95-106.
    • (2000) Biochemistry , vol.65 , pp. 95-106
    • Stavrovskaya, A.A.1
  • 87
    • 0035954243 scopus 로고    scopus 로고
    • Induction of apoptosis in MDR1 expressing cells by daunorubicin with combinations of suboptimal concentrations of P-glycoprotein modulators
    • Aszalos A, Ladanyi A, Bocsi J, Szende B. Induction of apoptosis in MDR1 expressing cells by daunorubicin with combinations of suboptimal concentrations of P-glycoprotein modulators. Cancer Let 2001;167:157-162.
    • (2001) Cancer Let , vol.167 , pp. 157-162
    • Aszalos, A.1    Ladanyi, A.2    Bocsi, J.3    Szende, B.4
  • 88
    • 0000073697 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS
    • Matsumura Y, Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS. Cancer Res 1986;6:193-210.
    • (1986) Cancer Res , vol.6 , pp. 193-210
    • Matsumura, Y.1    Maeda, H.2
  • 90
    • 0036096806 scopus 로고    scopus 로고
    • Liposome-based drug delivery in breast cancer treatment
    • Park JW. Liposome-based drug delivery in breast cancer treatment. Breast Cancer Res 2002;4:95-99.
    • (2002) Breast Cancer Res , vol.4 , pp. 95-99
    • Park, J.W.1
  • 91
    • 33646473959 scopus 로고    scopus 로고
    • Therapeutic potential of controlled drug delivery systems in neurodegenerative diseases
    • Popovic N, Brundin P. Therapeutic potential of controlled drug delivery systems in neurodegenerative diseases. Int J Pharmaceut 2006;314:120-126.
    • (2006) Int J Pharmaceut , vol.314 , pp. 120-126
    • Popovic, N.1    Brundin, P.2
  • 92
  • 93
    • 33745588040 scopus 로고    scopus 로고
    • A new polymer-lipid hybrid nanoparticle system increases cytotoxicity of doxorubicin against multidrug resistant human breast cancer cells
    • Wong HL, Rauth AM, Bendayan R, Manias JL, Ramaswamy M, Liu Z, Erhan SZ, Wu XY. A new polymer-lipid hybrid nanoparticle system increases cytotoxicity of doxorubicin against multidrug resistant human breast cancer cells. Pharm Res 2006;23:1574-1585.
    • (2006) Pharm Res , vol.23 , pp. 1574-1585
    • Wong, H.L.1    Rauth, A.M.2    Bendayan, R.3    Manias, J.L.4    Ramaswamy, M.5    Liu, Z.6    Erhan, S.Z.7    Wu, X.Y.8
  • 95
    • 0033941681 scopus 로고    scopus 로고
    • Intraperitoneal injection of dextran sulfate as an anti-adherent drug for the prevention of peritoneal metastasis of cancer shows low toxicity in animals
    • Hagiwara A, Sakakura C, Shirasu M, Togawa T, Sonoyama Y, Fujiyama J, Ebihara Y, Itoh T, Yamagishi H. Intraperitoneal injection of dextran sulfate as an anti-adherent drug for the prevention of peritoneal metastasis of cancer shows low toxicity in animals. Anti-Cancer Drugs 2000;11:393-399.
    • (2000) Anti-cancer Drugs , vol.11 , pp. 393-399
    • Hagiwara, A.1    Sakakura, C.2    Shirasu, M.3    Togawa, T.4    Sonoyama, Y.5    Fujiyama, J.6    Ebihara, Y.7    Itoh, T.8    Yamagishi, H.9
  • 96
    • 0029875854 scopus 로고    scopus 로고
    • On the mechanism of action of doxorubicin encapsulation in nanospheres for the reversal of multidrug resistance
    • Hu YP, Jarillon S, Dubernet C, Couvreur P, Robert J. On the mechanism of action of doxorubicin encapsulation in nanospheres for the reversal of multidrug resistance. Cancer Chemother Pharmacol 1996;37:556-560.
    • (1996) Cancer Chemother Pharmacol , vol.37 , pp. 556-560
    • Hu, Y.P.1    Jarillon, S.2    Dubernet, C.3    Couvreur, P.4    Robert, J.5
  • 97
    • 0028914767 scopus 로고
    • Potentiation of anticancer-drug cytotoxicity by multidrugresistance chemosensitizers involves alterations in membrane fluidity leading to increased membrane permeability
    • Drori S, Eytan GD, Assaraf YG. Potentiation of anticancer-drug cytotoxicity by multidrugresistance chemosensitizers involves alterations in membrane fluidity leading to increased membrane permeability. Eur J Biochem 1995;228:1020-1029.
    • (1995) Eur J Biochem , vol.228 , pp. 1020-1029
    • Drori, S.1    Eytan, G.D.2    Assaraf, Y.G.3
  • 98
    • 0015349672 scopus 로고
    • Potentiation of drug effect by Tween 80 in Chinese Hamster cells resistant to actinomycin D and daunomycin
    • Riehm H, Biedler JL. Potentiation of drug effect by Tween 80 in Chinese Hamster cells resistant to actinomycin D and daunomycin. Cancer Res 1972;32:1195-1200.
    • (1972) Cancer Res , vol.32 , pp. 1195-1200
    • Riehm, H.1    Biedler, J.L.2
  • 99
    • 0037072478 scopus 로고    scopus 로고
    • Pluronic block copolymers for overcoming drug resistance in cancer
    • Kabanov AV, Batrakova EV, Alakhov VY. Pluronic block copolymers for overcoming drug resistance in cancer. Adv Drug Del Rev 2002;54:759-779.
    • (2002) Adv Drug Del Rev , vol.54 , pp. 759-779
    • Kabanov, A.V.1    Batrakova, E.V.2    Alakhov, V.Y.3
  • 100
    • 0027509809 scopus 로고
    • The effects of lipids and detergents on ATPase activity of P-glycoprotein
    • Doige CA, Yu X, Sharom FJ. The effects of lipids and detergents on ATPase activity of P-glycoprotein. Biochim Biophys Acta 1993;1146:65-72.
    • (1993) Biochim Biophys Acta , vol.1146 , pp. 65-72
    • Doige, C.A.1    Yu, X.2    Sharom, F.J.3
  • 101
    • 0034988558 scopus 로고    scopus 로고
    • Triton-X-100-modified polymer and microspheres for reversal of multidrug resistance
    • Liu Z, Bendayan R, Wu XY. Triton-X-100-modified polymer and microspheres for reversal of multidrug resistance. J Pharm Pharmacol 2001;53:1-12.
    • (2001) J Pharm Pharmacol , vol.53 , pp. 1-12
    • Liu, Z.1    Bendayan, R.2    Wu, X.Y.3
  • 102
    • 0031665981 scopus 로고    scopus 로고
    • Effects of pluronic P85 unimers and micelles on drug permeability in polarized BBMEC and Caco-2 cells
    • Batrakova EV, Han HY, Miller DW, Kabanov AV. Effects of pluronic P85 unimers and micelles on drug permeability in polarized BBMEC and Caco-2 cells. Pharm Res 1998;15:1525-1532.
    • (1998) Pharm Res , vol.15 , pp. 1525-1532
    • Batrakova, E.V.1    Han, H.Y.2    Miller, D.W.3    Kabanov, A.V.4
  • 103
    • 0031656495 scopus 로고    scopus 로고
    • Block copolymeric biotransport carriers as versatile vehicles for drug delivery
    • Alakhov VY, Kabanov AV. Block copolymeric biotransport carriers as versatile vehicles for drug delivery. Exp Opin Invest Drugs 1998;7:1453-1473.
    • (1998) Exp Opin Invest Drugs , vol.7 , pp. 1453-1473
    • Alakhov, V.Y.1    Kabanov, A.V.2
  • 104
    • 0030111359 scopus 로고    scopus 로고
    • Hypersensitization of multidrug resistant human ovarian carcinoma cells by pluronic P85 block copolymer
    • Alakhov VY, Moskaleva EY, Batrakova EV. Hypersensitization of multidrug resistant human ovarian carcinoma cells by pluronic P85 block copolymer. Bioconjug Chem 1996;7:209-216.
    • (1996) Bioconjug Chem , vol.7 , pp. 209-216
    • Alakhov, V.Y.1    Moskaleva, E.Y.2    Batrakova, E.V.3
  • 105
    • 0141955916 scopus 로고    scopus 로고
    • An essential relationship between ATP depletion and chemosensitizing activity of pluronic block copolymers
    • Kabonov AV, Batrakova EV, Alakhov VY. An essential relationship between ATP depletion and chemosensitizing activity of pluronic block copolymers. J Control Release 2003;91:75-83.
    • (2003) J Control Release , vol.91 , pp. 75-83
    • Kabonov, A.V.1    Batrakova, E.V.2    Alakhov, V.Y.3
  • 106
    • 0034757615 scopus 로고    scopus 로고
    • Mechanism of pluronic effect on p-glycoprotein efflux system in blood brain barrier: Contributions of energy depletion and membrane fluidization
    • Batrakova EV, Li S, Vinogradov SV, Alakhov VY, Miller DW, Kabanov AV. Mechanism of pluronic effect on p-glycoprotein efflux system in blood brain barrier: contributions of energy depletion and membrane fluidization. J Pharmacol Exp Ther 2001;299:483-493.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 483-493
    • Batrakova, E.V.1    Li, S.2    Vinogradov, S.V.3    Alakhov, V.Y.4    Miller, D.W.5    Kabanov, A.V.6
  • 107
    • 0037173520 scopus 로고    scopus 로고
    • Incorporation of cyclosporin A in solid lipid nanoparticles (SLN)
    • Ugazio E, Cavali R, Gasco MR. Incorporation of cyclosporin A in solid lipid nanoparticles (SLN). Int J Pharm 2002;241:341-344.
    • (2002) Int J Pharm , vol.241 , pp. 341-344
    • Ugazio, E.1    Cavali, R.2    Gasco, M.R.3
  • 108
    • 0035845755 scopus 로고    scopus 로고
    • Effect of PSC 833 liposomes and intralipid on the transport of epirubicin in Caco-2 cells and rat intestines
    • Lo YL, Liu FI, Cheung JY. Effect of PSC 833 liposomes and intralipid on the transport of epirubicin in Caco-2 cells and rat intestines. J Control Release 2001;76:1-10.
    • (2001) J Control Release , vol.76 , pp. 1-10
    • Lo, Y.L.1    Liu, F.I.2    Cheung, J.Y.3
  • 109
    • 3843150602 scopus 로고    scopus 로고
    • Development of solid lipid nanoparticles containing ionically-complexed chemotherapeutic drugs and chemosensitizers
    • Wong HL, Bendayan R, Rauth AM, Wu XY. Development of solid lipid nanoparticles containing ionically-complexed chemotherapeutic drugs and chemosensitizers. J Pharm Sci 2004;93:1993-2004.
    • (2004) J Pharm Sci , vol.93 , pp. 1993-2004
    • Wong, H.L.1    Bendayan, R.2    Rauth, A.M.3    Wu, X.Y.4
  • 110
    • 37849185909 scopus 로고    scopus 로고
    • Combinational treatment with doxorubicin and GG918 (Elacridar) using polymer-lipid hybrid nanoparticles (PLN) and evaluation of strategies for multidrug-resistance reversal in human breast cancer cells
    • Wong HL, Rauth AM, Bendayan R, Wu XY. Combinational treatment with doxorubicin and GG918 (Elacridar) using polymer-lipid hybrid nanoparticles (PLN) and evaluation of strategies for multidrug-resistance reversal in human breast cancer cells. J Control Release 2006;116:275-284.
    • (2006) J Control Release , vol.116 , pp. 275-284
    • Wong, H.L.1    Rauth, A.M.2    Bendayan, R.3    Wu, X.Y.4
  • 111
    • 40149102354 scopus 로고    scopus 로고
    • On the synergistic effect of doxorubicin and mitomycin C against breast cancer cells
    • Shuhendler AJ, O'Brien P, Rauth AM, Wu XY. On the synergistic effect of doxorubicin and mitomycin C against breast cancer cells. Drug Metabol Drug Interactions 2008;22:201-233.
    • (2008) Drug Metabol Drug Interactions , vol.22 , pp. 201-233
    • Shuhendler, A.J.1    O'Brien, P.2    Rauth, A.M.3    Wu, X.Y.4
  • 112
    • 84900137877 scopus 로고    scopus 로고
    • A novel doxorubicinmitomycin C co-encapsulated nanoparticle formulation exhibits anti-cancer synergy inmultidrug resistant human breast cancer cells
    • submitted in
    • Shuhendler AJ, Chung R, Manias J, Connor A, Rauth AM, Wu XY. A novel doxorubicinmitomycin C co-encapsulated nanoparticle formulation exhibits anti-cancer synergy inmultidrug resistant human breast cancer cells. Breast Cancer Res Treatment, submitted in 2008.
    • (2008) Breast Cancer Res Treatment
    • Shuhendler, A.J.1    Chung, R.2    Manias, J.3    Connor, A.4    Rauth, A.M.5    Wu, X.Y.6
  • 113
    • 33745253111 scopus 로고    scopus 로고
    • Selective gene delivery for cancer therapy using cationic liposomes: In vivo proof of applicability
    • Dass CR, Choong PFM. Selective gene delivery for cancer therapy using cationic liposomes: In vivo proof of applicability. J Control Release 2006;113:155-163.
    • (2006) J Control Release , vol.113 , pp. 155-163
    • Dass, C.R.1    Choong, P.F.M.2
  • 114
    • 33645500266 scopus 로고    scopus 로고
    • Progress towards in vivo use of siRNAs
    • Behlke M. Progress towards in vivo use of siRNAs. Mol Therapy 2006;13:645-670.
    • (2006) Mol Therapy , vol.13 , pp. 645-670
    • Behlke, M.1
  • 116
    • 33644593889 scopus 로고    scopus 로고
    • Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery
    • Khalil IA, Kogure K, Akita H. Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery. Pharmacol Rev 2006;58:32-45.
    • (2006) Pharmacol Rev , vol.58 , pp. 32-45
    • Khalil, I.A.1    Kogure, K.2    Akita, H.3
  • 117
    • 0037335187 scopus 로고    scopus 로고
    • Direct evidence that polysorbate-80-coated poly (butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles
    • Kreuter J, Ramge P, Petrov V, Hamm S, Gelperina SE, Engelhardt B, Alyautdin R, von Briesen H, Begley DJ. Direct evidence that polysorbate-80- coated poly (butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles. Pharm Res 2003;20:409-416.
    • (2003) Pharm Res , vol.20 , pp. 409-416
    • Kreuter, J.1    Ramge, P.2    Petrov, V.3    Hamm, S.4    Gelperina, S.E.5    Engelhardt, B.6    Alyautdin, R.7    Von Briesen, H.8    Begley, D.J.9
  • 120
    • 0035017308 scopus 로고    scopus 로고
    • Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER
    • Pelkmans L, Kartenbeck J, Helenius A. Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER. Nat Cell Biol 2001;3:473-483.
    • (2001) Nat Cell Biol , vol.3 , pp. 473-483
    • Pelkmans, L.1    Kartenbeck, J.2    Helenius, A.3
  • 122
    • 11844268027 scopus 로고    scopus 로고
    • Cationic TAT peptide transduction domain enters cells by macropinocytosis
    • Kaplan IM, Wadia JS, Dowdy SF. Cationic TAT peptide transduction domain enters cells by macropinocytosis. J Control Release 2005;102:247-253.
    • (2005) J Control Release , vol.102 , pp. 247-253
    • Kaplan, I.M.1    Wadia, J.S.2    Dowdy, S.F.3
  • 123
    • 33645640345 scopus 로고    scopus 로고
    • High density of octaarginine stimulates macropinocytosis leading to efficient intracellular trafficking for gene expression
    • Khalil IA, Kogure K, Futaki S, Harashima H. High density of octaarginine stimulates macropinocytosis leading to efficient intracellular trafficking for gene expression. J Biol Chem 2006;6:3544-3551.
    • (2006) J Biol Chem , vol.6 , pp. 3544-3551
    • Khalil, I.A.1    Kogure, K.2    Futaki, S.3    Harashima, H.4
  • 124
    • 21644487837 scopus 로고    scopus 로고
    • Folate receptor-mediated gene delivery using folate-poly (ethylene glycol)-poly (L-lysine) conjugate
    • Cho KC, Kim SH, Jeong JH, Park TG. Folate receptor-mediated gene delivery using folate-poly (ethylene glycol)-poly (L-lysine) conjugate. Macromol Biosci 2005;5:512-519.
    • (2005) Macromol Biosci , vol.5 , pp. 512-519
    • Cho, K.C.1    Kim, S.H.2    Jeong, J.H.3    Park, T.G.4
  • 125
    • 42949166258 scopus 로고    scopus 로고
    • Quantum Dots for Cancer Diagnosis and Therapy
    • Zhang H, Yee D, Wang C. Quantum Dots for Cancer Diagnosis and Therapy. Biol Clin Perspectives 2008;3:83-91.
    • (2008) Biol Clin Perspectives , vol.3 , pp. 83-91
    • Zhang, H.1    Yee, D.2    Wang, C.3
  • 126
    • 17644366858 scopus 로고    scopus 로고
    • A folate-receptor-targeted lipid nanoparticle formulation for a lipophilic paclitaxel prodrug
    • Stevens PJ, Sekido M, Lee RJ. A folate-receptor-targeted lipid nanoparticle formulation for a lipophilic paclitaxel prodrug. Pharm Res 2004;21:2153-2157.
    • (2004) Pharm Res , vol.21 , pp. 2153-2157
    • Stevens, P.J.1    Sekido, M.2    Lee, R.J.3
  • 127
    • 33646798446 scopus 로고    scopus 로고
    • Amechanistic study of enhanced doxorubicin uptake and retention in multidrug resistant breast cancer cells using a polymer-lipid hybrid nanoparticle (PLN) system
    • Wong HL, Bendayan R, Rauth AM, Xue HY, Babakhanian K, Wu XY. Amechanistic study of enhanced doxorubicin uptake and retention in multidrug resistant breast cancer cells using a polymer-lipid hybrid nanoparticle (PLN) system. J Pharmacol Exp Ther 2006;317:1372-1381.
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 1372-1381
    • Wong, H.L.1    Bendayan, R.2    Rauth, A.M.3    Xue, H.Y.4    Babakhanian, K.5    Wu, X.Y.6
  • 128
    • 0041181628 scopus 로고    scopus 로고
    • HPMA copolymer-anticancer drug conjugates: Design, activity, and mechanism of action
    • Kopecek J, Kopeckova P, Minko T, Lu ZR. HPMA copolymer-anticancer drug conjugates: design, activity, and mechanism of action. Eur J Pharm Biopharm 2000;50:61-81.
    • (2000) Eur J Pharm Biopharm , vol.50 , pp. 61-81
    • Kopecek, J.1    Kopeckova, P.2    Minko, T.3    Lu, Z.R.4
  • 130
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997;3:730-737.
    • (1997) Nat Med , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 133
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • O'Brien CA, Pollett A, Gallinger S, Dick JE. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007;445:106-110.
    • (2007) Nature , vol.445 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3    Dick, J.E.4
  • 134
    • 23044514578 scopus 로고    scopus 로고
    • Multiple drug resistance in cancer revisited: The cancer stem cell hypothesis
    • Donnenberg VS, Donnenberg AD. Multiple drug resistance in cancer revisited: the cancer stem cell hypothesis. J Clin Pharmacol 2005;45:872-877.
    • (2005) J Clin Pharmacol , vol.45 , pp. 872-877
    • Donnenberg, V.S.1    Donnenberg, A.D.2
  • 135
    • 4644306516 scopus 로고    scopus 로고
    • A distinct "side population" of cells with high drug efflux capacity in human tumor cells
    • Hirschmann-Jax C, Foster AE, Wulf GG. A distinct "side population" of cells with high drug efflux capacity in human tumor cells. Proc Natl Acad Sci USA 2004;101:14228-14233.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 14228-14233
    • Hirschmann-Jax, C.1    Foster, A.E.2    Wulf, G.G.3
  • 137
    • 18144371163 scopus 로고    scopus 로고
    • Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs
    • Gouaze V, Liu YY, Prickett CS, Yu JY, Giuliano AE, Cabot MC. Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs. Cancer Res 2005;65:3861-3867.
    • (2005) Cancer Res , vol.65 , pp. 3861-3867
    • Gouaze, V.1    Liu, Y.Y.2    Prickett, C.S.3    Yu, J.Y.4    Giuliano, A.E.5    Cabot, M.C.6
  • 138
    • 32144447613 scopus 로고    scopus 로고
    • Suppression of glucosylceramide synthase by RNA interference reverses multidrug resistance in human breast cancer cells
    • Sun YL, Zhou GY, Li KN, Gao P, Zhang QH, Zhen JH, Bai YH, Zhang XF. Suppression of glucosylceramide synthase by RNA interference reverses multidrug resistance in human breast cancer cells. Neoplasma 2006;53:1-8.
    • (2006) Neoplasma , vol.53 , pp. 1-8
    • Sun, Y.L.1    Zhou, G.Y.2    Li, K.N.3    Gao, P.4    Zhang, Q.H.5    Zhen, J.H.6    Bai, Y.H.7    Zhang, X.F.8
  • 141
    • 34250365663 scopus 로고    scopus 로고
    • P-glycoprotein mediates celecoxib-induced apoptosis in multiple drug-resistant cell lines
    • Fantappiè O, Solazzo M, Lasagna N, Platini F, Tessitore L, Mazzant R. P-glycoprotein mediates celecoxib-induced apoptosis in multiple drug-resistant cell lines. Cancer Res 2007;67:4915-4923.
    • (2007) Cancer Res , vol.67 , pp. 4915-4923
    • Fantappiè, O.1    Solazzo, M.2    Lasagna, N.3    Platini, F.4    Tessitore, L.5    Mazzant, R.6
  • 144
    • 21744437791 scopus 로고    scopus 로고
    • Repopulation of cancer cells during therapy: An important cause of treatment failure
    • Kim JJ, Tannock IF. Repopulation of cancer cells during therapy: An important cause of treatment failure. Nat Rev Cancer 2005;5:516-525.
    • (2005) Nat Rev Cancer , vol.5 , pp. 516-525
    • Kim, J.J.1    Tannock, I.F.2
  • 145
    • 33847284493 scopus 로고    scopus 로고
    • Evaluation of the in vivo efficacy, toxicity and lymphatic drainage of loco-regional administered polymer-lipid hybrid nanoparticles (PLN) loaded with doxorubicin in a murine solid tumor model
    • Wong HL, Rauth AM, Bendayan R, Wu XY. Evaluation of the in vivo efficacy, toxicity and lymphatic drainage of loco-regional administered polymer-lipid hybrid nanoparticles (PLN) loaded with doxorubicin in a murine solid tumor model. Eur J Pharm Biopharm 2007;65:300-308.
    • (2007) Eur J Pharm Biopharm , vol.65 , pp. 300-308
    • Wong, H.L.1    Rauth, A.M.2    Bendayan, R.3    Wu, X.Y.4
  • 146
    • 0035126527 scopus 로고    scopus 로고
    • Enhancement of paclitaxel delivery to solid tumors by apoptosis-inducing pretreatment: Effect of treatment schedule
    • Jang SH, Wientjes MG, Au JL. Enhancement of paclitaxel delivery to solid tumors by apoptosis-inducing pretreatment: effect of treatment schedule. J Pharmacol Exp Ther 2001;296:1035-1042.
    • (2001) J Pharmacol Exp Ther , vol.296 , pp. 1035-1042
    • Jang, S.H.1    Wientjes, M.G.2    Au, J.L.3
  • 147
    • 19944422751 scopus 로고    scopus 로고
    • Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: Role of oxygenation, angiopoietin-1, and matrix metalloproteinases
    • Winkler F, Kozin SV, Tong RT, Chae S, Booth M, Garkavtsev I, Xu L, Hicklin D, Fukumura D, Tomaso ED. Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases. Cancer Cell 2004;6:553-563.
    • (2004) Cancer Cell , vol.6 , pp. 553-563
    • Winkler, F.1    Kozin, S.V.2    Tong, R.T.3    Chae, S.4    Booth, M.5    Garkavtsev, I.6    Xu, L.7    Hicklin, D.8    Fukumura, D.9    Tomaso, E.D.10
  • 148
    • 0038578294 scopus 로고    scopus 로고
    • Dynamic imaging of collagen and its modulation in tumors in vivo using secondharmonic generation
    • Brown E, Mckee T, di Tomaso, Pluen A, Seed B, Boucher Y, Rakesh K. Jain RK. Dynamic imaging of collagen and its modulation in tumors in vivo using secondharmonic generation. Nat Med 2003;9:796-800.
    • (2003) Nat Med , vol.9 , pp. 796-800
    • Brown, E.1    Mckee, T.2    Di Tomaso3    Pluen, A.4    Seed, B.5    Boucher, Y.6    Rakesh, K.7    Jain, R.K.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.