Intraperitoneal injection of dextran sulfate as an anti-adherent drug for the prevention of peritoneal metastasis of cancer shows low toxicity in animals

Anti-Cancer Drugs

Volumn 11, Issue 5, 2000, Pages 393-399

  Hagiwara, Akeo ^a   Sakakura, Chouhei ^a   Shirasu, Morio ^a   Togawa, Takeshi ^a   Sonoyama, Yoshinobu ^a   Fujiyama, Junshin ^a   Ebihara, Yoshimasa ^a   Itoh, Tadao ^a   Yamagishi, Hisakazu ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Anti cancer cell adherent therapy; Dextran sulfate; Peritoneal metastasis; Toxicity

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; DEXTRAN SULFATE; HEMOGLOBIN;

ARTICLE; BODY WEIGHT; DRUG INTOXICATION; DRUG SAFETY; HEMATOCRIT; LETHAL DOSE; LEUKOCYTE COUNT; MOLECULAR WEIGHT; MORTALITY; ORGAN WEIGHT; PERITONEUM METASTASIS; PRIORITY JOURNAL; RABBIT;

ANIMALS; ANTINEOPLASTIC AGENTS; BLOOD CHEMICAL ANALYSIS; BODY WEIGHT; CELL ADHESION; DEXTRAN SULFATE; INJECTIONS, INTRAPERITONEAL; INTESTINE, SMALL; LETHAL DOSE 50; MALE; MICE; NEOPLASM METASTASIS; PERITONEAL NEOPLASMS; RABBITS;

EID: 0033941681     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-200006000-00010     Document Type: Article

References (3)

1. 1. Hagiwara A, Sawai K, Sakakura C, et al. Prevention of peritoneal metastasis of cancer with dextran sulfate - an experimental study in mice. Anti-Cancer Drugs 1997; 8: 894-7.
2. 2. Finny DJ. Probit analysis. London: Cambridge University Press 1980.
3. 3. Togawa T. The mechanism of dextran sulfate as a prophylaxis of peritoneal cancer metastasis. J Kyoto Prefectural University of Medicine 1999; 108: 711-23 (in Japanese with English summary).