Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs

Cancer Research

Volumn 65, Issue 9, 2005, Pages 3861-3867

  Gouazé, Valérie ^a   Liu, Yong Yu ^a   Prickett, Carlton S ^a   Yu, Jing Y ^a   Giuliano, Armando E ^a   Cabot, Myles C ^a  

^a JOHN WAYNE CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 PHENYL 2 PALMITOYLAMINO 3 MORPHOLINO 1 PROPANOL; ANTINEOPLASTIC AGENT; CERAMIDE; CERAMIDE GLUCOSYLTRANSFERASE; GANGLIOSIDE; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; PROPANOL; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VINBLASTINE;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER RESISTANCE; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION;

ADENOCARCINOMA; BREAST NEOPLASMS; CELL LINE, TUMOR; DOWN-REGULATION; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; GANGLIOSIDES; GLUCOSYLTRANSFERASES; HUMANS; MORPHOLINES; OLIGONUCLEOTIDES, ANTISENSE; P-GLYCOPROTEIN; PACLITAXEL; SPHINGOLIPIDS; TRANSFECTION; VINBLASTINE;

EID: 18144371163     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-2329     Document Type: Article

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