메뉴 건너뛰기




Volumn 320, Issue 1-2, 2012, Pages 45-51

Phosphodiesterase inhibitor modulation of brain microvascular endothelial cell barrier properties

Author keywords

Cell culture; Endothelial; Histamine; Microcirculation; Phosphodiesterase

Indexed keywords

ALBUMIN; CILOSTAZOL; CLAUDIN 5; DEXTRAN; DIPYRIDAMOLE; F ACTIN; HISTAMINE; KT 5720; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHODIESTERASE INHIBITOR; ROLIPRAM;

EID: 84864606742     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2012.06.005     Document Type: Article
Times cited : (26)

References (73)
  • 1
    • 58549098084 scopus 로고    scopus 로고
    • Blood-brain barrier: Ageing and microvascular disease - Systematic review and meta-analysis
    • A.J. Farrall, and J.M. Wardlaw Blood-brain barrier: ageing and microvascular disease - systematic review and meta-analysis Neurobiol Aging 30 3 2009 337 352
    • (2009) Neurobiol Aging , vol.30 , Issue.3 , pp. 337-352
    • Farrall, A.J.1    Wardlaw, J.M.2
  • 2
    • 74849117723 scopus 로고    scopus 로고
    • The neurovascular unit in the setting of stroke
    • G.J. del Zoppo The neurovascular unit in the setting of stroke J Intern Med 267 2 2010 156 171
    • (2010) J Intern Med , vol.267 , Issue.2 , pp. 156-171
    • Del Zoppo, G.J.1
  • 3
    • 77956326640 scopus 로고    scopus 로고
    • The blood-brain barrier: Geriatric relevance of a critical brain-body interface
    • N. Zeevi, J. Pachter, L.D. McCullough, L. Wolfson, and G.A. Kuchel The blood-brain barrier: geriatric relevance of a critical brain-body interface J Am Geriatr Soc 58 9 2010 1749 1757
    • (2010) J Am Geriatr Soc , vol.58 , Issue.9 , pp. 1749-1757
    • Zeevi, N.1    Pachter, J.2    McCullough, L.D.3    Wolfson, L.4    Kuchel, G.A.5
  • 4
    • 78149240465 scopus 로고    scopus 로고
    • The challenge of mixed cerebrovascular disease
    • M. Fisher The challenge of mixed cerebrovascular disease Ann N Y Acad Sci 1207 2010 18 22
    • (2010) Ann N y Acad Sci , vol.1207 , pp. 18-22
    • Fisher, M.1
  • 5
    • 78650415912 scopus 로고    scopus 로고
    • Cerebral microbleeds in the elderly: A pathological analysis
    • M. Fisher, S. French, P. Ji, and R.C. Kim Cerebral microbleeds in the elderly: a pathological analysis Stroke 41 12 2010 2782 2785
    • (2010) Stroke , vol.41 , Issue.12 , pp. 2782-2785
    • Fisher, M.1    French, S.2    Ji, P.3    Kim, R.C.4
  • 6
    • 28044448943 scopus 로고    scopus 로고
    • Pericapillary haem-rich deposits: Evidence for microhaemorrhages in aging human cerebral cortex
    • K.M. Cullen, Z. Kocsi, and J. Stone Pericapillary haem-rich deposits: evidence for microhaemorrhages in aging human cerebral cortex J Cereb Blood Flow Metab 25 12 2005 1656 1667
    • (2005) J Cereb Blood Flow Metab , vol.25 , Issue.12 , pp. 1656-1667
    • Cullen, K.M.1    Kocsi, Z.2    Stone, J.3
  • 7
    • 53049101053 scopus 로고    scopus 로고
    • Neuropathologic correlates of white matter hyperintensities
    • V.G. Young, G.M. Halliday, and J.J. Kril Neuropathologic correlates of white matter hyperintensities Neurology 71 11 2008 804 811
    • (2008) Neurology , vol.71 , Issue.11 , pp. 804-811
    • Young, V.G.1    Halliday, G.M.2    Kril, J.J.3
  • 8
    • 67049154557 scopus 로고    scopus 로고
    • Use of antithrombotic drugs and the presence of cerebral microbleeds: The Rotterdam Scan Study
    • M.W. Vernooij, M.D. Haag, A. van der Lugt, A. Hofman, G.P. Krestin, and B.H. Stricker Use of antithrombotic drugs and the presence of cerebral microbleeds: the Rotterdam Scan Study Arch Neurol 66 6 2009 714 720
    • (2009) Arch Neurol , vol.66 , Issue.6 , pp. 714-720
    • Vernooij, M.W.1    Haag, M.D.2    Van Der Lugt, A.3    Hofman, A.4    Krestin, G.P.5    Stricker, B.H.6
  • 9
    • 32944473849 scopus 로고    scopus 로고
    • Cilostazol in secondary prevention of stroke: Impact of the Cilostazol Stroke Prevention Study
    • M. Matsumoto Cilostazol in secondary prevention of stroke: impact of the Cilostazol Stroke Prevention Study Atheroscler Suppl 6 4 2005 33 40
    • (2005) Atheroscler Suppl , vol.6 , Issue.4 , pp. 33-40
    • Matsumoto, M.1
  • 10
    • 44049106204 scopus 로고    scopus 로고
    • Protective effects of cilostazol against transient focal cerebral ischemia and chronic cerebral hypoperfusion injury
    • J.H. Lee, S.Y. Park, H.K. Shin, C.D. Kim, W.S. Lee, and K.W. Hong Protective effects of cilostazol against transient focal cerebral ischemia and chronic cerebral hypoperfusion injury CNS Neurosci Ther 14 2 2008 143 152
    • (2008) CNS Neurosci Ther , vol.14 , Issue.2 , pp. 143-152
    • Lee, J.H.1    Park, S.Y.2    Shin, H.K.3    Kim, C.D.4    Lee, W.S.5    Hong, K.W.6
  • 11
    • 77956884231 scopus 로고    scopus 로고
    • Cilostazol for prevention of secondary stroke (CSPS 2): An aspirin-controlled, double-blind, randomised non-inferiority trial
    • Y. Shinohara, Y. Katayama, S. Uchiyama, T. Yamaguchi, S. Handa, and K. Matsuoka Cilostazol for prevention of secondary stroke (CSPS 2): an aspirin-controlled, double-blind, randomised non-inferiority trial Lancet Neurol 9 10 2010 959 968
    • (2010) Lancet Neurol , vol.9 , Issue.10 , pp. 959-968
    • Shinohara, Y.1    Katayama, Y.2    Uchiyama, S.3    Yamaguchi, T.4    Handa, S.5    Matsuoka, K.6
  • 12
    • 33847672708 scopus 로고    scopus 로고
    • Re-discovering PDE3 inhibitors - New opportunities for a long neglected target
    • P.E. Thompson, V. Manganiello, and E. Degerman Re-discovering PDE3 inhibitors - new opportunities for a long neglected target Curr Top Med Chem 7 4 2007 421 436
    • (2007) Curr Top Med Chem , vol.7 , Issue.4 , pp. 421-436
    • Thompson, P.E.1    Manganiello, V.2    Degerman, E.3
  • 13
    • 31144433061 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents
    • C. Lugnier Cyclic nucleotide phosphodiesterase (PDE) superfamily: a new target for the development of specific therapeutic agents Pharmacol Ther 109 3 2006 366 398
    • (2006) Pharmacol Ther , vol.109 , Issue.3 , pp. 366-398
    • Lugnier, C.1
  • 14
    • 79953329375 scopus 로고    scopus 로고
    • PDE4D and PDE4B function in distinct subcellular compartments in mouse embryonic fibroblasts
    • B.E. Blackman, K. Horner, J. Heidmann, D. Wang, W. Richter, and T.C. Rich PDE4D and PDE4B function in distinct subcellular compartments in mouse embryonic fibroblasts J Biol Chem 286 2011 12590 12601
    • (2011) J Biol Chem , vol.286 , pp. 12590-12601
    • Blackman, B.E.1    Horner, K.2    Heidmann, J.3    Wang, D.4    Richter, W.5    Rich, T.C.6
  • 15
    • 34447265905 scopus 로고    scopus 로고
    • Biochemistry and physiology of cyclic nucleotide phosphodiesterases: Essential components in cyclic nucleotide signaling
    • M. Conti, and J. Beavo Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling Annu Rev Biochem 76 2007 481 511
    • (2007) Annu Rev Biochem , vol.76 , pp. 481-511
    • Conti, M.1    Beavo, J.2
  • 16
    • 0031702870 scopus 로고    scopus 로고
    • Dipyridamole trials in stroke prevention
    • H.C. Diener Dipyridamole trials in stroke prevention Neurology 51 3 Suppl 3 1998 S17 S19
    • (1998) Neurology , vol.51 , Issue.3 SUPPL 3
    • Diener, H.C.1
  • 17
    • 78149241207 scopus 로고    scopus 로고
    • Effect of dipyridamole during acute stroke: Exploring antithrombosis and neuroprotective benefits
    • C.D. d'Esterre, and T.Y. Lee Effect of dipyridamole during acute stroke: exploring antithrombosis and neuroprotective benefits Ann N Y Acad Sci 1207 2010 71 75
    • (2010) Ann N y Acad Sci , vol.1207 , pp. 71-75
    • D'Esterre, C.D.1    Lee, T.Y.2
  • 18
    • 33750317276 scopus 로고    scopus 로고
    • Tadalafil, a long-acting type 5 phosphodiesterase isoenzyme inhibitor, improves neurological functional recovery in a rat model of embolic stroke
    • L. Zhang, Z. Zhang, R.L. Zhang, Y. Cui, M.C. LaPointe, and B. Silver Tadalafil, a long-acting type 5 phosphodiesterase isoenzyme inhibitor, improves neurological functional recovery in a rat model of embolic stroke Brain Res 1118 1 2006 192 198
    • (2006) Brain Res , vol.1118 , Issue.1 , pp. 192-198
    • Zhang, L.1    Zhang, Z.2    Zhang, R.L.3    Cui, Y.4    Lapointe, M.C.5    Silver, B.6
  • 19
    • 0034279221 scopus 로고    scopus 로고
    • Both protein kinase A and mitogen-activated protein kinase are required in the amygdala for the macromolecular synthesis-dependent late phase of long-term potentiation
    • Y.-Y. Huang, K.C. Martin, and E.R. Kandel Both protein kinase A and mitogen-activated protein kinase are required in the amygdala for the macromolecular synthesis-dependent late phase of long-term potentiation J Neurosci 20 17 2000 6317 6325
    • (2000) J Neurosci , vol.20 , Issue.17 , pp. 6317-6325
    • Huang, Y.-Y.1    Martin, K.C.2    Kandel, E.R.3
  • 20
    • 0142138142 scopus 로고    scopus 로고
    • A simple method for isolation and characterization of mouse brain microvascular endothelial cells
    • Z. Wu, F.M. Hofman, and B.V. Zlokovic A simple method for isolation and characterization of mouse brain microvascular endothelial cells J Neurosci Methods 130 1 2003 53 63
    • (2003) J Neurosci Methods , vol.130 , Issue.1 , pp. 53-63
    • Wu, Z.1    Hofman, F.M.2    Zlokovic, B.V.3
  • 21
    • 73549089880 scopus 로고    scopus 로고
    • Epac1 mediates protein kinase A-independent mechanism of forskolin-activated intestinal chloride secretion
    • K.M. Hoque, O.M. Woodward, D.B. van Rossum, N.C. Zachos, L. Chen, and G.P. Leung Epac1 mediates protein kinase A-independent mechanism of forskolin-activated intestinal chloride secretion J Gen Physiol 135 1 2010 43 58
    • (2010) J Gen Physiol , vol.135 , Issue.1 , pp. 43-58
    • Hoque, K.M.1    Woodward, O.M.2    Van Rossum, D.B.3    Zachos, N.C.4    Chen, L.5    Leung, G.P.6
  • 22
    • 11144305139 scopus 로고    scopus 로고
    • Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway
    • S. Fukuhara, A. Sakurai, H. Sano, A. Yamagishi, S. Somekawa, and N. Takakura Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway Mol Cell Biol 25 1 2005 136 146
    • (2005) Mol Cell Biol , vol.25 , Issue.1 , pp. 136-146
    • Fukuhara, S.1    Sakurai, A.2    Sano, H.3    Yamagishi, A.4    Somekawa, S.5    Takakura, N.6
  • 23
    • 33846565008 scopus 로고    scopus 로고
    • Cilostazol inhibits the redistribution of the actin cytoskeleton and junctional proteins on the blood-brain barrier under hypoxia/reoxygenation
    • H. Torii, H. Kubota, H. Ishihara, and M. Suzuki Cilostazol inhibits the redistribution of the actin cytoskeleton and junctional proteins on the blood-brain barrier under hypoxia/reoxygenation Pharmacol Res 55 2 2007 104 110
    • (2007) Pharmacol Res , vol.55 , Issue.2 , pp. 104-110
    • Torii, H.1    Kubota, H.2    Ishihara, H.3    Suzuki, M.4
  • 24
    • 79551501886 scopus 로고    scopus 로고
    • Lipoamide or lipoic acid stimulates mitochondrial biogenesis in 3T3-L1 adipocytes via the endothelial NO synthase-cGMP-protein kinase G signalling pathway
    • W. Shen, J. Hao, Z. Feng, C. Tian, W. Chen, and L. Packer Lipoamide or lipoic acid stimulates mitochondrial biogenesis in 3T3-L1 adipocytes via the endothelial NO synthase-cGMP-protein kinase G signalling pathway Br J Pharmacol 162 5 2011 1213 1224
    • (2011) Br J Pharmacol , vol.162 , Issue.5 , pp. 1213-1224
    • Shen, W.1    Hao, J.2    Feng, Z.3    Tian, C.4    Chen, W.5    Packer, L.6
  • 25
    • 79954630982 scopus 로고    scopus 로고
    • Activation of MEK1/ERK1/2/iNOS/sGC/PKG pathway associated with peroxynitrite formation contributes to hypotension and vascular hyporeactivity in endotoxemic rats
    • B. Korkmaz, K. Buharalioglu, S. Sahan-Firat, T,. Cuez, A. Tuncay Demiryurek, and B. Tunctan Activation of MEK1/ERK1/2/iNOS/sGC/PKG pathway associated with peroxynitrite formation contributes to hypotension and vascular hyporeactivity in endotoxemic rats Nitric Oxide 24 3 2011 160 172
    • (2011) Nitric Oxide , vol.24 , Issue.3 , pp. 160-172
    • Korkmaz, B.1    Buharalioglu, K.2    Sahan-Firat, S.3    Cuez, T.4    Tuncay Demiryurek, A.5    Tunctan, B.6
  • 27
    • 39349095242 scopus 로고    scopus 로고
    • Alkaline pH- and cAMP-induced V-ATPase membrane accumulation is mediated by protein kinase A in epididymal clear cells
    • N.M. Pastor-Soler, K.R. Hallows, C. Smolak, F. Gong, D. Brown, and S. Breton Alkaline pH- and cAMP-induced V-ATPase membrane accumulation is mediated by protein kinase A in epididymal clear cells Am J Physiol Cell Physiol 294 2 2008 C488 C494
    • (2008) Am J Physiol Cell Physiol , vol.294 , Issue.2
    • Pastor-Soler, N.M.1    Hallows, K.R.2    Smolak, C.3    Gong, F.4    Brown, D.5    Breton, S.6
  • 28
    • 0031031742 scopus 로고    scopus 로고
    • In vitro models to predict blood-brain barrier permeability
    • E.P. Eddy, B.E. Maleef, T.K. Hart, and P.L. Smith In vitro models to predict blood-brain barrier permeability Adv Drug Deliv Rev 23 1-3 1997 185 198
    • (1997) Adv Drug Deliv Rev , vol.23 , Issue.13 , pp. 185-198
    • Eddy, E.P.1    Maleef, B.E.2    Hart, T.K.3    Smith, P.L.4
  • 29
    • 17444406065 scopus 로고    scopus 로고
    • Permeability studies on in vitro blood-brain barrier models: Physiology, pathology, and pharmacology
    • M.A. Deli, C.S. Abraham, Y. Kataoka, and M. Niwa Permeability studies on in vitro blood-brain barrier models: physiology, pathology, and pharmacology Cell Mol Neurobiol 25 1 2005 59 127
    • (2005) Cell Mol Neurobiol , vol.25 , Issue.1 , pp. 59-127
    • Deli, M.A.1    Abraham, C.S.2    Kataoka, Y.3    Niwa, M.4
  • 31
    • 44149106107 scopus 로고    scopus 로고
    • CAMP induced Rac 1-mediated cytoskeletal reorganization in microvascular endothelium
    • Y. Baumer, D. Drenckhahn, and J. Waschke cAMP induced Rac 1-mediated cytoskeletal reorganization in microvascular endothelium Histochem Cell Biol 129 6 2008 765 778
    • (2008) Histochem Cell Biol , vol.129 , Issue.6 , pp. 765-778
    • Baumer, Y.1    Drenckhahn, D.2    Waschke, J.3
  • 32
  • 33
    • 77749279859 scopus 로고    scopus 로고
    • Nitric oxide-induced changes in endothelial expression of phosphodiesterases 2, 3, and 5
    • C.J. Schankin, L.S. Kruse, V.M. Reinisch, S. Jungmann, J.C. Kristensen, and S. Grau Nitric oxide-induced changes in endothelial expression of phosphodiesterases 2, 3, and 5 Headache 50 3 2010 431 441
    • (2010) Headache , vol.50 , Issue.3 , pp. 431-441
    • Schankin, C.J.1    Kruse, L.S.2    Reinisch, V.M.3    Jungmann, S.4    Kristensen, J.C.5    Grau, S.6
  • 34
    • 0033985281 scopus 로고    scopus 로고
    • Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity
    • T. Sudo, K. Tachibana, K. Toga, S. Tochizawa, Y. Inoue, and Y. Kimura Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity Biochem Pharmacol 59 4 2000 347 356
    • (2000) Biochem Pharmacol , vol.59 , Issue.4 , pp. 347-356
    • Sudo, T.1    Tachibana, K.2    Toga, K.3    Tochizawa, S.4    Inoue, Y.5    Kimura, Y.6
  • 35
    • 0035544829 scopus 로고    scopus 로고
    • Cilostazol (pletal): A dual inhibitor of cyclic nucleotide phosphodiesterase type 3 and adenosine uptake
    • Y. Liu, Y. Shakur, M. Yoshitake, and J. Ji Kambayashi Cilostazol (pletal): a dual inhibitor of cyclic nucleotide phosphodiesterase type 3 and adenosine uptake Cardiovasc Drug Rev 19 4 2001 369 386
    • (2001) Cardiovasc Drug Rev , vol.19 , Issue.4 , pp. 369-386
    • Liu, Y.1    Shakur, Y.2    Yoshitake, M.3    Kambayashi, J.J.4
  • 36
    • 1942484380 scopus 로고    scopus 로고
    • Analysis of the effects of phosphodiesterase type 3 and 4 inhibitors in cerebral arteries
    • S. Birk, L. Edvinsson, J. Olesen, and C. Kruuse Analysis of the effects of phosphodiesterase type 3 and 4 inhibitors in cerebral arteries Eur J Pharmacol 489 1-2 2004 93 100
    • (2004) Eur J Pharmacol , vol.489 , Issue.12 , pp. 93-100
    • Birk, S.1    Edvinsson, L.2    Olesen, J.3    Kruuse, C.4
  • 37
    • 0347416957 scopus 로고    scopus 로고
    • Phosphorylation of the vasodilator-stimulated phosphoprotein (VASP) by the anti-platelet drug, cilostazol, in platelets
    • T. Sudo, H. Ito, and Y. Kimura Phosphorylation of the vasodilator-stimulated phosphoprotein (VASP) by the anti-platelet drug, cilostazol, in platelets Platelets 14 6 2003 381 390
    • (2003) Platelets , vol.14 , Issue.6 , pp. 381-390
    • Sudo, T.1    Ito, H.2    Kimura, Y.3
  • 38
    • 40749113625 scopus 로고    scopus 로고
    • Translational therapeutics of dipyridamole
    • H.H. Kim, and J.K. Liao Translational therapeutics of dipyridamole Arterioscler Thromb Vasc Biol 28 3 2008 s39 s42
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , Issue.3
    • Kim, H.H.1    Liao, J.K.2
  • 41
    • 0029775029 scopus 로고    scopus 로고
    • Signal transduction and glial cell modulation of cultured brain microvessel endothelial cell tight junctions
    • T.J. Raub Signal transduction and glial cell modulation of cultured brain microvessel endothelial cell tight junctions Am J Physiol 271 2 Pt 1 1996 C495 C503
    • (1996) Am J Physiol , vol.271 , Issue.2 PART 1
    • Raub, T.J.1
  • 42
    • 0141535306 scopus 로고    scopus 로고
    • Human blood-derived macrophages enhance barrier function of cultured primary bovine and human brain capillary endothelial cells
    • D. Zenker, D. Begley, H. Bratzke, H. Rubsamen-Waigmann, and H. von Briesen Human blood-derived macrophages enhance barrier function of cultured primary bovine and human brain capillary endothelial cells J Physiol 551 Pt 3 2003 1023 1032
    • (2003) J Physiol , vol.551 , Issue.PART 3 , pp. 1023-1032
    • Zenker, D.1    Begley, D.2    Bratzke, H.3    Rubsamen-Waigmann, H.4    Von Briesen, H.5
  • 43
    • 79955709685 scopus 로고    scopus 로고
    • Blockade of phosphodiesterase-III protects against oxygen-glucose deprivation in endothelial cells by upregulation of VE-cadherin
    • M. Ishiguro, Y. Suzuki, K. Mishiro, M. Kakino, K. Tsuruma, and M. Shimazawa Blockade of phosphodiesterase-III protects against oxygen-glucose deprivation in endothelial cells by upregulation of VE-cadherin Curr Neurovasc Res 8 2 2011 86 94
    • (2011) Curr Neurovasc Res , vol.8 , Issue.2 , pp. 86-94
    • Ishiguro, M.1    Suzuki, Y.2    Mishiro, K.3    Kakino, M.4    Tsuruma, K.5    Shimazawa, M.6
  • 44
    • 78650163900 scopus 로고    scopus 로고
    • Phosphodiesterase-III inhibitor prevents hemorrhagic transformation induced by focal cerebral ischemia in mice treated with tPA
    • M. Ishiguro, K. Mishiro, Y. Fujiwara, H. Chen, H. Izuta, and K. Tsuruma Phosphodiesterase-III inhibitor prevents hemorrhagic transformation induced by focal cerebral ischemia in mice treated with tPA PLoS One 5 12 2010 e15178
    • (2010) PLoS One , vol.5 , Issue.12 , pp. 15178
    • Ishiguro, M.1    Mishiro, K.2    Fujiwara, Y.3    Chen, H.4    Izuta, H.5    Tsuruma, K.6
  • 45
    • 0034754016 scopus 로고    scopus 로고
    • The kinetics, function, and regulation of P-selectin expressed by human brain microvessel endothelial cells in primary culture
    • A.S. Easton, and K. Dorovini-Zis The kinetics, function, and regulation of P-selectin expressed by human brain microvessel endothelial cells in primary culture Microvasc Res 62 3 2001 335 345
    • (2001) Microvasc Res , vol.62 , Issue.3 , pp. 335-345
    • Easton, A.S.1    Dorovini-Zis, K.2
  • 46
    • 0032937268 scopus 로고    scopus 로고
    • Treatment with BBB022A or rolipram stabilizes the blood-brain barrier in experimental autoimmune encephalomyelitis: An additional mechanism for the therapeutic effect of type IV phosphodiesterase inhibitors
    • V.A. Folcik, T. Smith, S. O'Bryant, J.A. Kawczak, B. Zhu, and H. Sakurai Treatment with BBB022A or rolipram stabilizes the blood-brain barrier in experimental autoimmune encephalomyelitis: an additional mechanism for the therapeutic effect of type IV phosphodiesterase inhibitors J Neuroimmunol 97 1-2 1999 119 128
    • (1999) J Neuroimmunol , vol.97 , Issue.12 , pp. 119-128
    • Folcik, V.A.1    Smith, T.2    O'Bryant, S.3    Kawczak, J.A.4    Zhu, B.5    Sakurai, H.6
  • 47
    • 77954878301 scopus 로고    scopus 로고
    • Amelioration of inflammation and cytotoxicity by dipyridamole in brain endothelial cells
    • S. Guo, M. Stins, M. Ning, and E.H. Lo Amelioration of inflammation and cytotoxicity by dipyridamole in brain endothelial cells Cerebrovasc Dis 30 3 2010 290 296
    • (2010) Cerebrovasc Dis , vol.30 , Issue.3 , pp. 290-296
    • Guo, S.1    Stins, M.2    Ning, M.3    Lo, E.H.4
  • 48
    • 0033192720 scopus 로고    scopus 로고
    • Cereport (RMP-7) increases the permeability of human brain microvascular endothelial cell monolayers
    • J.B. Mackic, M. Stins, S. Jovanovic, K.S. Kim, R.T. Bartus, and B.V. Zlokovic Cereport (RMP-7) increases the permeability of human brain microvascular endothelial cell monolayers Pharm Res 16 9 1999 1360 1365
    • (1999) Pharm Res , vol.16 , Issue.9 , pp. 1360-1365
    • MacKic, J.B.1    Stins, M.2    Jovanovic, S.3    Kim, K.S.4    Bartus, R.T.5    Zlokovic, B.V.6
  • 49
    • 83755183462 scopus 로고    scopus 로고
    • Tissue plasminogen activator expression and barrier properties of human brain microvascular endothelial cells
    • F. Yang, S. Liu, S.J. Wang, C. Yu, A. Paganini-Hill, and M.J. Fisher Tissue plasminogen activator expression and barrier properties of human brain microvascular endothelial cells Cell Physiol Biochem 28 4 2011 631 638
    • (2011) Cell Physiol Biochem , vol.28 , Issue.4 , pp. 631-638
    • Yang, F.1    Liu, S.2    Wang, S.J.3    Yu, C.4    Paganini-Hill, A.5    Fisher, M.J.6
  • 50
    • 79952492956 scopus 로고    scopus 로고
    • Cilostazol enhances integrin-dependent homing of progenitor cells by activation of cAMP-dependent protein kinase in synergy with Epac1
    • D.H. Lee, H.R. Lee, H.K. Shin, S.Y. Park, K.W. Hong, and E.K. Kim Cilostazol enhances integrin-dependent homing of progenitor cells by activation of cAMP-dependent protein kinase in synergy with Epac1 J Neurosci Res 89 2011 650 660
    • (2011) J Neurosci Res , vol.89 , pp. 650-660
    • Lee, D.H.1    Lee, H.R.2    Shin, H.K.3    Park, S.Y.4    Hong, K.W.5    Kim, E.K.6
  • 51
    • 84862789135 scopus 로고    scopus 로고
    • PDE4 regulates tissue plasminogen activator expression of human brain microvascular endothelial cells
    • F. Yang, S. Liu, C. Yu, S.J. Wang, A. Paganini-Hill, and M.J. Fisher PDE4 regulates tissue plasminogen activator expression of human brain microvascular endothelial cells Thromb Res 129 2012 750 753
    • (2012) Thromb Res , vol.129 , pp. 750-753
    • Yang, F.1    Liu, S.2    Yu, C.3    Wang, S.J.4    Paganini-Hill, A.5    Fisher, M.J.6
  • 52
    • 0033761535 scopus 로고    scopus 로고
    • Phosphodiesterases and cyclic nucleotide signaling in endocrine cells
    • M. Conti Phosphodiesterases and cyclic nucleotide signaling in endocrine cells Mol Endocrinol 14 9 2000 1317 1327
    • (2000) Mol Endocrinol , vol.14 , Issue.9 , pp. 1317-1327
    • Conti, M.1
  • 53
    • 77949472038 scopus 로고    scopus 로고
    • Compartmentalized cyclic adenosine 3′,5′-monophosphate at the plasma membrane clusters PDE3A and cystic fibrosis transmembrane conductance regulator into microdomains
    • H. Penmatsa, W. Zhang, S. Yarlagadda, C. Li, V.G. Conoley, and J. Yue Compartmentalized cyclic adenosine 3′,5′-monophosphate at the plasma membrane clusters PDE3A and cystic fibrosis transmembrane conductance regulator into microdomains Mol Biol Cell 21 6 2010 1097 1110
    • (2010) Mol Biol Cell , vol.21 , Issue.6 , pp. 1097-1110
    • Penmatsa, H.1    Zhang, W.2    Yarlagadda, S.3    Li, C.4    Conoley, V.G.5    Yue, J.6
  • 54
    • 28844435999 scopus 로고    scopus 로고
    • Compartmentalization of adenylate cyclase and cAMP signalling
    • D.M. Cooper Compartmentalization of adenylate cyclase and cAMP signalling Biochem Soc Trans 33 Pt 6 2005 1319 1322
    • (2005) Biochem Soc Trans , vol.33 , Issue.PART 6 , pp. 1319-1322
    • Cooper, D.M.1
  • 55
    • 0034990531 scopus 로고    scopus 로고
    • Role of cAMP-dependent protein kinase A activity in endothelial cell cytoskeleton rearrangement
    • F. Liu, A.D. Verin, T. Borbiev, and J.G. Garcia Role of cAMP-dependent protein kinase A activity in endothelial cell cytoskeleton rearrangement Am J Physiol Lung Cell Mol Physiol 280 6 2001 L1309 L1317
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.280 , Issue.6
    • Liu, F.1    Verin, A.D.2    Borbiev, T.3    Garcia, J.G.4
  • 56
    • 59849129267 scopus 로고    scopus 로고
    • The actin cytoskeleton in endothelial cell phenotypes
    • N. Prasain, and T. Stevens The actin cytoskeleton in endothelial cell phenotypes Microvasc Res 77 1 2009 53 63
    • (2009) Microvasc Res , vol.77 , Issue.1 , pp. 53-63
    • Prasain, N.1    Stevens, T.2
  • 57
    • 29244463365 scopus 로고    scopus 로고
    • Astrocyte-endothelial interactions at the blood-brain barrier
    • N.J. Abbott, L. Ronnback, and E. Hansson Astrocyte-endothelial interactions at the blood-brain barrier Nat Rev Neurosci 7 1 2006 41 53
    • (2006) Nat Rev Neurosci , vol.7 , Issue.1 , pp. 41-53
    • Abbott, N.J.1    Ronnback, L.2    Hansson, E.3
  • 58
    • 0142026252 scopus 로고    scopus 로고
    • Cyclic AMP induces phosphorylation of claudin-5 immunoprecipitates and expression of claudin-5 gene in blood-brain-barrier endothelial cells via protein kinase A-dependent and -independent pathways
    • T. Ishizaki, H. Chiba, T. Kojima, M. Fujibe, T. Soma, and H. Miyajima Cyclic AMP induces phosphorylation of claudin-5 immunoprecipitates and expression of claudin-5 gene in blood-brain-barrier endothelial cells via protein kinase A-dependent and -independent pathways Exp Cell Res 290 2 2003 275 288
    • (2003) Exp Cell Res , vol.290 , Issue.2 , pp. 275-288
    • Ishizaki, T.1    Chiba, H.2    Kojima, T.3    Fujibe, M.4    Soma, T.5    Miyajima, H.6
  • 59
    • 34248173562 scopus 로고    scopus 로고
    • A functional in vitro model of rat blood-brain barrier for molecular analysis of efflux transporters
    • N. Perrière, S. Yousif, S. Cazaubon, N. Chaverot, F. Bourasset, and S. Cisternino A functional in vitro model of rat blood-brain barrier for molecular analysis of efflux transporters Brain Res 1150 2007 1 13
    • (2007) Brain Res , vol.1150 , pp. 1-13
    • Perrière, N.1    Yousif, S.2    Cazaubon, S.3    Chaverot, N.4    Bourasset, F.5    Cisternino, S.6
  • 61
    • 78951495581 scopus 로고    scopus 로고
    • Histamine: New thoughts about a familiar mediator
    • B.L. Jones, and G.L. Kearns Histamine: new thoughts about a familiar mediator Clin Pharmacol Ther 89 2011 189 197
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 189-197
    • Jones, B.L.1    Kearns, G.L.2
  • 62
    • 0033962411 scopus 로고    scopus 로고
    • Inflammatory mediators and modulation of blood-brain barrier permeability
    • N.J. Abbott Inflammatory mediators and modulation of blood-brain barrier permeability Cell Mol Neurobiol 20 2 2000 131 147
    • (2000) Cell Mol Neurobiol , vol.20 , Issue.2 , pp. 131-147
    • Abbott, N.J.1
  • 63
    • 0032583083 scopus 로고    scopus 로고
    • Transient and prolonged increase in endothelial permeability induced by histamine and thrombin: Role of protein kinases, calcium, and RhoA
    • G.P. van Nieuw Amerongen, R. Draijer, M.A. Vermeer, and V.W. van Hinsbergh Transient and prolonged increase in endothelial permeability induced by histamine and thrombin: role of protein kinases, calcium, and RhoA Circ Res 83 11 1998 1115 1123
    • (1998) Circ Res , vol.83 , Issue.11 , pp. 1115-1123
    • Van Nieuw Amerongen, G.P.1    Draijer, R.2    Vermeer, M.A.3    Van Hinsbergh, V.W.4
  • 64
    • 33749143832 scopus 로고    scopus 로고
    • Histamine-induced phosphorylation of the regulatory light chain of myosin II disrupts the barrier integrity of corneal endothelial cells
    • S.P. Srinivas, M. Satpathy, Y. Guo, and V. Anandan Histamine-induced phosphorylation of the regulatory light chain of myosin II disrupts the barrier integrity of corneal endothelial cells Invest Ophthalmol Vis Sci 47 9 2006 4011 4018
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , Issue.9 , pp. 4011-4018
    • Srinivas, S.P.1    Satpathy, M.2    Guo, Y.3    Anandan, V.4
  • 65
    • 0344826048 scopus 로고    scopus 로고
    • Histamine induces cytoskeletal changes in human eosinophils via the H(4) receptor
    • K.F. Buckland, T.J. Williams, and D.M. Conroy Histamine induces cytoskeletal changes in human eosinophils via the H(4) receptor Br J Pharmacol 140 6 2003 1117 1127
    • (2003) Br J Pharmacol , vol.140 , Issue.6 , pp. 1117-1127
    • Buckland, K.F.1    Williams, T.J.2    Conroy, D.M.3
  • 66
    • 34548590352 scopus 로고    scopus 로고
    • Histamine-induced myosin light chain phosphorylation breaks down the barrier integrity of cultured corneal epithelial cells
    • Y. Guo, C. Ramachandran, M. Satpathy, and S.P. Srinivas Histamine-induced myosin light chain phosphorylation breaks down the barrier integrity of cultured corneal epithelial cells Pharm Res 24 10 2007 1824 1833
    • (2007) Pharm Res , vol.24 , Issue.10 , pp. 1824-1833
    • Guo, Y.1    Ramachandran, C.2    Satpathy, M.3    Srinivas, S.P.4
  • 67
    • 0031951374 scopus 로고    scopus 로고
    • 2 +]i and force in middle cerebral artery of the rabbit
    • 2 +]i and force in middle cerebral artery of the rabbit Br J Pharmacol 123 5 1998 869 878
    • (1998) Br J Pharmacol , vol.123 , Issue.5 , pp. 869-878
    • Shiraishi, Y.1    Kanmura, Y.2    Itoh, T.3
  • 68
    • 0028246186 scopus 로고
    • Modulation of tight junction structure in blood-brain barrier endothelial cells. Effects of tissue culture, second messengers and cocultured astrocytes
    • H. Wolburg, J. Neuhaus, U. Kniesel, B. Krauss, E. Schmid, and M. Ocalan Modulation of tight junction structure in blood-brain barrier endothelial cells. Effects of tissue culture, second messengers and cocultured astrocytes J Cell Sci 107 5 1994 1347 1357
    • (1994) J Cell Sci , vol.107 , Issue.5 , pp. 1347-1357
    • Wolburg, H.1    Neuhaus, J.2    Kniesel, U.3    Krauss, B.4    Schmid, E.5    Ocalan, M.6
  • 69
    • 51649106480 scopus 로고    scopus 로고
    • Cilostazol inhibits oxidative stress-induced premature senescence via upregulation of Sirt1 in human endothelial cells
    • H. Ota, M. Eto, M.R. Kano, S. Ogawa, K. Iijima, and M. Akishita Cilostazol inhibits oxidative stress-induced premature senescence via upregulation of Sirt1 in human endothelial cells Arterioscler Thromb Vasc Biol 28 9 2008 1634 1639
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , Issue.9 , pp. 1634-1639
    • Ota, H.1    Eto, M.2    Kano, M.R.3    Ogawa, S.4    Iijima, K.5    Akishita, M.6
  • 70
    • 1442319158 scopus 로고    scopus 로고
    • The pharmacology of cilostazol
    • K. Schror The pharmacology of cilostazol Diabetes Obes Metab 4 Suppl. 2 2002 S14 S19
    • (2002) Diabetes Obes Metab , vol.4 , Issue.SUPPL. 2
    • Schror, K.1
  • 71
    • 33750369864 scopus 로고    scopus 로고
    • Activation of endothelial nitric oxide synthase by cilostazol via a cAMP/protein kinase A-and phosphatidylinositol 3-kinase/Akt-dependent mechanism
    • Hashimoto Activation of endothelial nitric oxide synthase by cilostazol via a cAMP/protein kinase A-and phosphatidylinositol 3-kinase/Akt-dependent mechanism Atherosclerosis 189 2 2006 350
    • (2006) Atherosclerosis , vol.189 , Issue.2 , pp. 350
    • Hashimoto1
  • 72
    • 77949904247 scopus 로고    scopus 로고
    • The effects of cilostazol on tissue oxygenation upon an ischemic-reperfusion injury in the mouse cerebrum
    • T. Morikawa, K. Hattori, M. Kajimura, and M. Suematsu The effects of cilostazol on tissue oxygenation upon an ischemic-reperfusion injury in the mouse cerebrum Adv Exp Med Biol 662 2010 89 94
    • (2010) Adv Exp Med Biol , vol.662 , pp. 89-94
    • Morikawa, T.1    Hattori, K.2    Kajimura, M.3    Suematsu, M.4
  • 73
    • 67650492748 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced endothelial barrier breakdown is cyclic adenosine monophosphate dependent in vivo and in vitro
    • N. Schlegel, Y. Baumer, D. Drenckhahn, and J. Waschke Lipopolysaccharide-induced endothelial barrier breakdown is cyclic adenosine monophosphate dependent in vivo and in vitro Crit Care Med 37 5 2009 1735 1743
    • (2009) Crit Care Med , vol.37 , Issue.5 , pp. 1735-1743
    • Schlegel, N.1    Baumer, Y.2    Drenckhahn, D.3    Waschke, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.