Cereport(TM) (RMP-7) increases the permeability of human brain microvascular endothelial cell monolayers

Pharmaceutical Research

Volumn 16, Issue 9, 1999, Pages 1360-1365

  Mackic, Jasmina B ^a   Stins, Monique ^a   Jovanovic, Suzana ^a   Kim, Kwang Sik ^a   Bartus, Raymond T ^b   Zlokovic, Berislav V ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b ALKERMES INC   (United States)

Author keywords

Bradykinin B2 receptor; Brain endothelium; Cereport; Human; Permeability

Indexed keywords

BRADYKININ B2 RECEPTOR AGONIST; CYCLIC AMP; CYCLIC GMP; DEXTRAN; INULIN; LOBRADIMIL; PHOSPHODIESTERASE; ROLIPRAM; BRADYKININ; BRADYKININ B2 RECEPTOR; BRADYKININ RECEPTOR; CARBON; DIAGNOSTIC AGENT; DRUG DERIVATIVE; PHOSPHODIESTERASE INHIBITOR; PURINE DERIVATIVE; RADIOACTIVE IODINE; TRITIUM; ZAPRINAST;

ARTICLE; BASOLATERAL MEMBRANE; BINDING AFFINITY; BRAIN BLOOD VESSEL; DOSE RESPONSE; DRUG DELIVERY SYSTEM; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM; BINDING COMPETITION; BLOOD BRAIN BARRIER; BRAIN CORTEX; CELL CULTURE; CYTOLOGY; DRUG EFFECT; METABOLISM; MICROCIRCULATION; PHYSIOLOGY; VASCULARIZATION;

BINDING, COMPETITIVE; BLOOD-BRAIN BARRIER; BRADYKININ; CARBON RADIOISOTOPES; CELLS, CULTURED; CEREBRAL CORTEX; DEXTRANS; ENDOTHELIUM, VASCULAR; HUMANS; INULIN; IODINE RADIOISOTOPES; MICROCIRCULATION; PHOSPHODIESTERASE INHIBITORS; PURINONES; RECEPTOR, BRADYKININ B2; RECEPTORS, BRADYKININ; ROLIPRAM; TRITIUM;

EID: 0033192720     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018938722768     Document Type: Article

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