Role of cAMP-dependent protein kinase A activity in endothelial cell cytoskeleton rearrangement

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 280, Issue 6 24-6, 2001, Pages

  Liu, Feng ^a   Verin, Alexander D ^a   Borbiev, Talai ^a   Garcia, Joe G N ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

Caldesmon; Mitogen activated protein kinase; Raf 1

Indexed keywords

ACTIN; CALDESMON; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; MYOSIN LIGHT CHAIN; RAF PROTEIN;

ANIMAL CELL; ARTICLE; CATTLE; CELL STRUCTURE; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVATION; ENZYME ACTIVITY; NONHUMAN; PHENOTYPE; PHOSPHORYLATION; PRIORITY JOURNAL; PULMONARY ARTERY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

EID: 0034990531     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2001.280.6.l1309     Document Type: Article

References (52)

1. 2 receptor mechanism
2. 2+-inhibitable adenylyl cyclase and pulmonary microvascular permeability
3. Abolition of actin bundling by phosphorylation of human erythrocyte protein 4.9
4. The actions of cyclic AMP-dependent protein kinase
5. Inhibition by cAMP of Rasdependent activation of Raf
6. Adenylyl cyclases and the interaction between calcium and cAMP signaling
7. Mammal-specific, ERK-dependent, caldesmon phosphorylation in smooth muscle
8. cAMP-dependent protein kinase inhibits the mitogenic action of vascular endothelial growth factor and fibroblast growth factor in capillary endothelial cells by blocking Raf activation
9. A role of MAP kinase in differentiated smooth muscle contraction evoked by α-adrenoreceptor stimulation
10. Caldesmon inhibits active crossbridge in unstimulated vascular smooth muscle: An antisense oligodeoxynucleotide approach
11. Structure and function of cyclic nucleotide-dependent protein kinases
12. Regulation of endothelial cell gap formation and barrier dysfunction: Role of myosin light chain phosphorylation
13. Myosin light chain kinase in endothelium: Molecular cloning and regulation
14. Regulation of endothelial cell gap formation and paracellular permeability
15. Adherent neutrophils activate endothelial myosin light chain kinase: Role in transendothelial migration
16. Pertussis toxin directly activates endothelial cell p42/44 MAP kinases via a novel signaling pathway
17. Activation of MAP kinase in airway smooth muscle
18. Activation of MAP kinases and phosphorylation of caldesmon in canine colonic smooth muscle
19. Mechanism of inhibition of Raf-1 by protein kinase A
20. 2-induced filamin redistribution in endothelial cells is modulated by the cyclic AMP-dependent protein kinase pathway
21. Phosphorylation of caldesmon by ERK MAP kinases in smooth muscle
22. Antiproliferative effect of elevated glucose in human microvascular endothelial cells
23. Role of the cyclic AMP-dependent protein kinase in signal transducton
24. erk mitogen-activated protein kinase in vitro and demonstration of another caldesmon kinase in intact gizzard smooth muscle
25. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
26. Adducin regulation: Definition of the calmodulin-binding domain and sites of phosphorylation by protein kinases A and C
27. Negative regulation of Raf-1 by phosphorylation of serine 621
28. Signal transduction and regulation of lung endothelial cell permeability. Interaction between calcium and cAMP
29. Protein kinase A activity is required for the budding of constitutive transport vesicles from the trans-Golgi network
30. 2+ sensitivity in rabbit smooth muscle
31. Mechanisms of cholera toxin prevention of thrombin- and PMA-induced endothelial cell barrier dysfunction
32. Regulation of endothelial barrier function by the cAMP-dependent protein kinase
33. Mechanisms of pertussis toxin-induced barrier dysfunction in bovine pulmonary artery endothelial cell monolayers
34. Caldesmon and a 20-kDa actin-binding fragment of caldesmon inhibit tension development in skinned gizzard muscle fiber bundles
35. Restoration of the cAMP second messenger pathway enhances cardiac preservation for transplantation in a heterotopic rat model
36. Inhibition of glycogenolysis in isolated rat hepatocytes by the Rp diastereomer of adenosine 3′,5′-phosphorothioate
37. Role of endothelial cell cytoskeleton in control of endothelial permeability
38. Role of tyrosine phosphorylation in thrombin-induced endothelial cell contraction and barrier function
39. Caldesmon, a novel regulatory protein in smooth muscle and non-muscle actomyosin system
40. 77 and vimentin and enhances albumin permeability across cultured bovine pulmonary artery endothelial cell monolayers
41. Control of cAMP in lung endothelial cell phenotypes. Implications for control of barrier function
42. 2+-inhibitable adenylyl cyclase modulates pulmonary artery endothelial cell cAMP content and barrier function
43. Mammalian membrane-bound adenylyl cyclases
44. cAMP-dependent protein kinase: Framework for a diverse family of regulatory enzymes
45. Biochemical regulation of the nonmuscle myosin light chain kinase isoform in bovine endothelium
46. Mechanisms of phorbol ester-induced endothelial cell barrier dysfunction: Role of Ras-dependent ERK activation
47. Regulation of endothelial cell gap formation and barrier function by myosin-associated phosphatase activities
48. Cyclic AMP-dependent phosphorylation of filamin in mammalian smooth muscle
49. Both N-terminal myosin-binding and C-terminal actin-binding sites on smooth muscle caldesmon are required for caldesmon-mediated inhibition of actin filament velocity
50. Cyclic GMP-mediated decrease in permeability of human umbilical and pulmonary artery endothelial cell monolayers
51. Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphate
52. Mitosis-specific phosphorylation causes 83K non-muscle caldesmon to dissociate from microfilaments