Histamine-induced phosphorylation of the regulatory light chain of myosin II disrupts the barrier integrity of corneal endothelial cells

Investigative Ophthalmology and Visual Science

Volumn 47, Issue 9, 2006, Pages 4011-4018

  Srinivas, Sangly P ^a   Satpathy, Minati ^a   Guo, Ying ^a   Anandan, Vasuki ^a  

^a INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CHELERYTHRINE; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; GLYCEROL; HISTAMINE; HORSERADISH PEROXIDASE; MYOSIN ADENOSINE TRIPHOSPHATASE; MYOSIN II; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN PHOSPHATASE; PHALLOIDIN; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PROTEIN KINASE C INHIBITOR; UREA; CALCIUM; HISTAMINE H1 RECEPTOR; MYOSIN LIGHT CHAIN KINASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CORNEA ENDOTHELIUM; COW; CYTOSKELETON; ENZYME ACTIVATION; ENZYME LOCALIZATION; GEL ELECTROPHORESIS; IMMUNOCYTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; CALCIUM SIGNALING; CATTLE; CELL CULTURE; CELL MEMBRANE PERMEABILITY; DRUG ANTAGONISM; DRUG EFFECT; FLUORESCENCE MICROSCOPY; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; TIGHT JUNCTION;

ACTINS; ANIMALS; BLOTTING, WESTERN; CALCIUM; CALCIUM SIGNALING; CATTLE; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; CYCLIC AMP; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOTHELIUM, CORNEAL; HISTAMINE; MICROSCOPY, FLUORESCENCE; MYOSIN LIGHT CHAINS; MYOSIN TYPE II; MYOSIN-LIGHT-CHAIN KINASE; MYOSIN-LIGHT-CHAIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN KINASE C; RECEPTORS, HISTAMINE H1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TETRADECANOYLPHORBOL ACETATE; TIGHT JUNCTIONS;

EID: 33749143832     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.05-1127     Document Type: Article

References (31)

1. Fischbarg J, Hernandez J, Liebovitch LS, Koniarek JP. The mechanism of fluid and electrolyte transport across corneal endothelium: critical revision and update of a model. Curr Eye Res. 1985;4:351-360.
2. Fischbarg J, Maurice DM. An update on corneal hydration control. Exp Eye Res. 2004;78:537-541.
3. Riley M. Pump and leak in regulation of fluid transport in rabbit cornea. Curr Eye Res. 1985;4:371-376.
4. Bonanno JA. Identity and regulation of ion transport mechanisms in the corneal endothelium. Prog Retin Eye Res. 2003;22:69-94.
5. Riley MV, Winkler BS, Starnes CA, et al. Regulation of corneal endothelial barrier function by adenosine, cyclic AMP, and protein kinases. Invest Ophthalmol Vis Sci. 1998;39:2076-2084.
6. Satpathy M, Gallagher P, Lizotte-Waniewski M, Srinivas SP. Thrombin-induced phosphorylation of the regulatory light chain of myosin II in cultured bovine corneal endothelial cells. Exp Eye Res. 2004;79:477-486.
7. Srinivas SP, Satpathy M, Gallagher P, et al. Adenosine induces dephosphorylation of myosin II regulatory light chain in cultured bovine corneal endothelial cells. Exp Eye Res. 2004;79:543-551.
8. Satpathy M, Gallagher P, Jin Y, Srinivas SP. Extracellular ATP opposes thrombin-induced myosin light chain phosphorylation and loss of barrier integrity in corneal endothelial cells. Exp Eye Res. 2005;81:183-192.
9. Madara JL, Moore R, Carlson S. Alteration of intestinal tight junction structure and permeability by cytoskeletal contraction. Am J Physiol. 1987;253:C854-C861.
10. Madara JL. Regulation of the movement of solutes across tight junctions. Annu Rev Physiol. 1998;60:143-159.
11. Garcia JG, Davis HW, Patterson CE. Regulation of endothelial cell gap formation and barrier dysfunction: role of myosin light chain phosphorylation. J Cell Physiol. 1995;163:510-522.
12. Turner JR, Rill BK, Carlson SL, Carnes D, et al. Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation. Am J Physiol. 1997;273:C1378-C1385.
13. Turner JR. 'Putting the squeeze' on the tight junction: understanding cytoskeletal regulation. Semin Cell Dev Biol. 2000;11:301-308.
14. Yuan SY. Protein kinase signaling in the modulation of microvascular permeability. Vascul Pharmacol. 2002;39:213-223.
15. Kamm KE, Stull JT. Dedicated myosin light chain kinases with diverse cellular functions. J Biol Chem. 2001;276:4527-4530.
16. Somlyo AP, Somlyo AV. Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol Rev. 2003;83:1325-1358.
17. Kolosova IA, Ma SF, Adyshev DM, et al. Role of CPI-17 in the regulation of endothelial cytoskeleton. Am J Physiol. 2004;287: L970-L980.
18. Qiao J, Huang F, Lum H. PKA inhibits RhoA activation: a protection mechanism against endothelial barrier dysfunction. Am J Physiol. 2003;284:L972-L980.
19. Lang P, Gesbert F, Delespine-Carmagnat M, et al. Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes. EMBO J. 1996;15:510-519.
20. Goeckeler ZM, Wysolmerski RB. Myosin phosphatase and cofilin mediate cAMP/PKA-induced decline in endothelial cell isometric tension and myosin II RLC phosphorylation. J Biol Chem. 2005;280:33083-33095.
21. Srinivas SP, Yeh JC, Ong A, Bonanno JA. Ca2+ mobilization in bovine corneal endothelial cells by P2 purinergic receptors. Curr Eye Res. 1998;17:994-1004.
22. Srinivas SP, Ong A, Goon L, Bonanno JA. Lysosomal Ca(2+) stores in bovine corneal endothelium. Invest Ophthalmol Vis Sci. 2002;43:2341-2350.
23. Hirase T, Kawashima S, Wong EY, Ueyama T, et al. Regulation of tight junction permeability and occludin phosphorylation by Rhoa-p160ROCK-dependent and -independent mechanisms. J Biol Chem. 2001;276:10423-10431.
24. Crawford KM, MacCallum DK, Ernst SA. Histamine H1 receptor-mediated Ca2+ signaling in cultured bovine corneal endothelial cells. Invest Ophthalmol Vis Sci. 1992;33:3041-3049.
25. Crawford KM, MacCallum DK, Ernst SA. Agonist-induced Ca2+ mobilization in cultured bovine and human corneal endothelial cells. Curr Eye Res. 1993;12:303-311.
26. Eto M, Ohmori T, Suzuki M, Furuya K, et al. A novel protein phosphatase-1 inhibitory protein potentiated by protein kinase C. Isolation from porcine aorta media and characterization. J Biochem (Tokyo). 1995;118:1104-1107.
27. Eto M, Senba S, Morita F, Yazawa M. Molecular cloning of a novel phosphorylation-dependent inhibitory protein of protein phosphatase-1 (CPI17) in smooth muscle: its specific localization in smooth muscle. FEBS Lett. 1997;410:356-360.
28. Tan-Allen KY, Sun XC, Bonanno JA. Characterization of adenosine receptors in bovine corneal endothelium. Exp Eye Res. 2005;80:687-696.
29. Eto M, Kitazawa T, Yazawa M, et al. Histamine-induced vasoconstriction involves phosphorylation of a specific inhibitor protein for myosin phosphatase by protein kinase C alpha and delta isoforms. J Biol Chem. 2001;276:29072-29078.
30. Riley MV, Winkler BS, Starnes CA, Peters MI. Adenosine promotes regulation of corneal hydration through cyclic adenosine monophosphate. Invest Ophthalmol Vis Sci. 1996;37:1-10.
31. Wigham CG, Turner HC, Swan J, Hodson SA. Modulation of corneal endothelial hydration control mechanisms by rolipram. Pflugers Arch. 2000;440:866-870.