Leptin restores adult hippocampal neurogenesis in a chronic unpredictable stress model of depression and reverses glucocorticoid-induced inhibition of GSK-3Β/Β-catenin signaling

Molecular Psychiatry

Volumn 17, Issue 8, 2012, Pages 790-808

  Garza, J C ^a   Guo, M ^a   Zhang, W ^a   Lu, X Y ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

catenin; chronic unpredictable stress; glucocorticoids; glycogen synthase kinase 3 ; leptin; neurogenesis

Indexed keywords

BETA CATENIN; DEXAMETHASONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; ISOPROTEIN; LEPTIN; LEPTIN RECEPTOR; SERINE; TYROSINE;

ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CHRONIC STRESS; CONTROLLED STUDY; DEPRESSION; DISEASE MODEL; ENZYME PHOSPHORYLATION; GROWTH INHIBITION; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RADIOFREQUENCY ABLATION; SIGNAL TRANSDUCTION; X IRRADIATION;

ANIMALS; BETA CATENIN; CELL PROLIFERATION; CELLS, CULTURED; CRANIAL IRRADIATION; DEPRESSION; DEXAMETHASONE; DISEASE MODELS, ANIMAL; GLYCOGEN SYNTHASE KINASE 3; HIPPOCAMPUS; LEPTIN; MALE; NEUROGENESIS; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STRESS, PSYCHOLOGICAL;

EID: 84864352752     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2011.161     Document Type: Article

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