Adeno-associated virus-mediated knockdown of melanocortin-4 receptor in the paraventricular nucleus of the hypothalamus promotes high-fat diet-induced hyperphagia and obesity

Journal of Endocrinology

Volumn 197, Issue 3, 2008, Pages 471-482

  Garza, Jacob C ^a   Kim, Chung Sub ^a   Liu, Jing ^a   Zhang, Wei ^a   Lu, Xin Yun ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DICER; MELANOCORTIN 4 RECEPTOR; MESSENGER RNA; PARVOVIRUS VECTOR; SHORT HAIRPIN RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FOOD INTAKE; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; HYPERPHAGIA; HYPOTHALAMUS PERIVENTRICULAR NUCLEUS; IN SITU HYBRIDIZATION; LIPID DIET; MALE; NONHUMAN; OBESITY; PATHOGENESIS; PRIORITY JOURNAL; RAT; RNA INTERFERENCE; WEIGHT GAIN;

ANIMALS; CORTICOTROPIN-RELEASING HORMONE; DEPENDOVIRUS; DIETARY FATS; GENE SILENCING; HUMANS; HYPERPHAGIA; MALE; OBESITY; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, MELANOCORTIN, TYPE 4; RIBONUCLEASE III; THYROTROPIN-RELEASING HORMONE;

EID: 44949092261     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1677/JOE-08-0009     Document Type: Article

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