-
1
-
-
7744243520
-
The DNA damage response: Sensing and signaling
-
DOI 10.1016/j.ceb.2004.09.005, PII S0955067404001413
-
McGowan, C. H. & Russell, P. The DNA damage response: sensing and signaling. Curr. Opin. Cell Biol. 16, 629-633 (2004). (Pubitemid 39463112)
-
(2004)
Current Opinion in Cell Biology
, vol.16
, Issue.6
, pp. 629-633
-
-
McGowan, C.H.1
Russell, P.2
-
2
-
-
33751419716
-
Surviving the breakup: The DNA damage checkpoint
-
DOI 10.1146/annurev.genet.40.051206.105231
-
Harrison, J. C. & Haber, J. E. Surviving the breakup: the DNA damage checkpoint. Annu. Rev. Genet. 40, 209-235 (2006). (Pubitemid 44956785)
-
(2006)
Annual Review of Genetics
, vol.40
, pp. 209-235
-
-
Harrison, J.C.1
Haber, J.E.2
-
3
-
-
10444237214
-
ATM signaling and genomic stability in response to DNA damage
-
DOI 10.1016/j.mrfmmm.2004.04.020, PII S002751070400377X, Stress Responses
-
Lavin, M. F. et al. ATM signaling and genomic stability in response to DNA damage. Mutat. Res. 569, 123-132 (2005). (Pubitemid 39643262)
-
(2005)
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
, vol.569
, Issue.1-2
, pp. 123-132
-
-
Lavin, M.F.1
Birrell, G.2
Chen, P.3
Kozlov, S.4
Scott, S.5
Gueven, N.6
-
4
-
-
36949005417
-
DNA damage signalling guards against activated oncogenes and tumour progression
-
DOI 10.1038/sj.onc.1210881, PII 1210881
-
Bartek, J., Bartkova, J. & Lukas, J. DNA damage signalling guards against activated oncogenes and tumour progression. Oncogene 26, 7773-7779 (2007). (Pubitemid 350242463)
-
(2007)
Oncogene
, vol.26
, Issue.56
, pp. 7773-7779
-
-
Bartek, J.1
Bartkova, J.2
Lukas, J.3
-
5
-
-
17244367849
-
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
-
DOI 10.1038/nature03482
-
Bartkova, J. et al. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 434, 864-870 (2005). (Pubitemid 40558993)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 864-870
-
-
Bartkova, J.1
Horejsi, Z.2
Koed, K.3
Kramer, A.4
Tort, F.5
Zleger, K.6
Guldberg, P.7
Sehested, M.8
Nesland, J.M.9
Lukas, C.10
Orntoft, T.11
Lukas, J.12
Bartek, J.13
-
6
-
-
17244366865
-
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
-
DOI 10.1038/nature03485
-
Gorgoulis, V. G. et al. Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 434, 907-913 (2005). (Pubitemid 40559004)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 907-913
-
-
Gorgoulis, V.G.1
Vassiliou, L.-V.F.2
Karakaidos, P.3
Zacharatos, P.4
Kotsinas, A.5
Liloglou, T.6
Venere, M.7
DiTullio Jr., R.A.8
Kastrinakis, N.G.9
Levy, B.10
Kletsas, D.11
Yoneta, A.12
Herlyn, M.13
Kittas, C.14
Halazonetis, T.D.15
-
7
-
-
0034676455
-
Surfing the p53 network
-
Vogelstein, B., Lane, D. & Levine, A. J. Surfing the p53 network. Nature 408, 307-310 (2000).
-
(2000)
Nature
, vol.408
, pp. 307-310
-
-
Vogelstein, B.1
Lane, D.2
Levine, A.J.3
-
8
-
-
53049087888
-
Bone morphogenetic protein-Smad pathway as drug targets for osteoporosis and cancer therapy
-
Li, B. Bone morphogenetic protein-Smad pathway as drug targets for osteoporosis and cancer therapy. Endocr. Metab. Immune Disord. Drug Targets 8, 208-219 (2008).
-
(2008)
Endocr. Metab. Immune Disord. Drug Targets
, vol.8
, pp. 208-219
-
-
Li, B.1
-
9
-
-
12344291865
-
Bone morphogenetic proteins
-
DOI 10.1080/08977190412331279890
-
Chen, D., Zhao, M. & Mundy, G. R. Bone morphogenetic proteins. Growth Factors 22, 233-241 (2004). (Pubitemid 40136452)
-
(2004)
Growth Factors
, vol.22
, Issue.4
, pp. 233-241
-
-
Chen, D.1
Zhao, M.2
Mundy, G.R.3
-
10
-
-
23044466047
-
Specificity and versatility in TGF-β signaling through smads
-
DOI 10.1146/annurev.cellbio.21.022404.142018
-
Feng, X. H. & Derynck, R. Specificity and versatility in tgf-beta signaling through Smads. Annu. Rev. Cell Dev. Biol. 21, 659-693 (2005). (Pubitemid 41740650)
-
(2005)
Annual Review of Cell and Developmental Biology
, vol.21
, pp. 659-693
-
-
Feng, X.-H.1
Derynck, R.2
-
11
-
-
2342488852
-
New insights into TGF-beta-Smad signalling
-
ten Dijke, P. & Hill, C. S. New insights into TGF-beta-Smad signalling. Trends Biochem. Sci. 29, 265-273 (2004).
-
(2004)
Trends Biochem. Sci.
, vol.29
, pp. 265-273
-
-
Ten Dijke, P.1
Hill, C.S.2
-
12
-
-
49849103199
-
Decoding the quantitative nature of TGF-beta/Smad signaling
-
Clarke, D. C. & Liu, X. Decoding the quantitative nature of TGF-beta/Smad signaling. Trends Cell Biol. 18, 430-442 (2008).
-
(2008)
Trends Cell Biol
, vol.18
, pp. 430-442
-
-
Clarke, D.C.1
Liu, X.2
-
13
-
-
27644494876
-
Smad transcription factors
-
DOI 10.1101/gad.1350705
-
Massague, J., Seoane, J. & Wotton, D. Smad transcription factors. Genes Dev. 19, 2783-2810 (2005). (Pubitemid 41739965)
-
(2005)
Genes and Development
, vol.19
, Issue.23
, pp. 2783-2810
-
-
Massague, J.1
Seoane, J.2
Wotton, D.3
-
14
-
-
36448936383
-
TGFβ-SMAD signal transduction: Molecular specificity and functional flexibility
-
DOI 10.1038/nrm2297, PII NRM2297
-
Schmierer, B. & Hill, C. S. TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility. Nat. Rev. Mol. Cell Biol. 8, 970-982 (2007). (Pubitemid 350174642)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.12
, pp. 970-982
-
-
Schmierer, B.1
Hill, C.S.2
-
15
-
-
33646929213
-
A Phosphatase Controls the Fate of Receptor-Regulated Smads
-
DOI 10.1016/j.cell.2006.05.015, PII S009286740600626X
-
Schilling, S. H., Datto, M. B. & Wang, X. F. A phosphatase controls the fate of receptor-regulated Smads. Cell 125, 838-840 (2006). (Pubitemid 43795194)
-
(2006)
Cell
, vol.125
, Issue.5
, pp. 838-840
-
-
Schilling, S.H.1
Datto, M.B.2
Wang, X.-F.3
-
16
-
-
0038400997
-
In or out? The dynamics of Smad nucleocytoplasmic shuttling
-
DOI 10.1016/S0962-8924(03)00075-8
-
Reguly, T. & Wrana, J. L. In or out? The dynamics of Smad nucleocytoplasmic shuttling. Trends Cell Biol. 13, 216-220 (2003). (Pubitemid 36556005)
-
(2003)
Trends in Cell Biology
, vol.13
, Issue.5
, pp. 216-220
-
-
Reguly, T.1
Wrana, J.L.2
-
17
-
-
3142546336
-
Cyclin-dependent kinases regulate the antiproliferative function of Smads
-
DOI 10.1038/nature02650
-
Matsuura, I. et al. Cyclin-dependent kinases regulate the antiproliferative function of Smads. Nature 430, 226-231 (2004). (Pubitemid 38902433)
-
(2004)
Nature
, vol.430
, Issue.6996
, pp. 226-231
-
-
Matsuura, I.1
Denissova, N.G.2
Wang, G.3
He, D.4
Long, J.5
Liu, F.6
-
18
-
-
53449085169
-
Integrating positional information at the level of Smad1/5/8
-
Eivers, E., Fuentealba, L. C. & De Robertis, E. M. Integrating positional information at the level of Smad1/5/8. Curr. Opin. Genet. Dev. 18, 304-310 (2008).
-
(2008)
Curr. Opin. Genet. Dev.
, vol.18
, pp. 304-310
-
-
Eivers, E.1
Fuentealba, L.C.2
De Robertis, E.M.3
-
19
-
-
33846688094
-
Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker
-
DOI 10.1016/j.molcel.2007.01.006, PII S109727650700010X
-
Sapkota, G., Alarcon, C., Spagnoli, F. M., Brivanlou, A. H. & Massague, J. Balancing BMP signaling through integrated inputs into the Smad1 linker. Mol. Cell 25, 441-454 (2007). (Pubitemid 46199289)
-
(2007)
Molecular Cell
, vol.25
, Issue.3
, pp. 441-454
-
-
Sapkota, G.1
Alarcon, C.2
Spagnoli, F.M.3
Brivanlou, A.H.4
Massague, J.5
-
20
-
-
47549090432
-
TGFbeta in cancer
-
Massague, J. TGFbeta in Cancer. Cell 134, 215-230 (2008).
-
(2008)
Cell
, vol.134
, pp. 215-230
-
-
Massague, J.1
-
21
-
-
0034829630
-
Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes
-
Zhou, X. P. et al. Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes. Am. J. Hum. Genet. 69, 704-711 (2001).
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 704-711
-
-
Zhou, X.P.1
-
22
-
-
42949160593
-
The bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancers
-
Kodach, L. L. et al. The bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancers. Gastroenterology 134, 1332-1341 (2008).
-
(2008)
Gastroenterology
, vol.134
, pp. 1332-1341
-
-
Kodach, L.L.1
-
23
-
-
0034972978
-
Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis
-
DOI 10.1038/88919
-
Howe, J. R. et al. Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis. Nat. Genet. 28, 184-187 (2001). (Pubitemid 32538067)
-
(2001)
Nature Genetics
, vol.28
, Issue.2
, pp. 184-187
-
-
Howe, J.R.1
Bair, J.L.2
Sayed, M.G.3
Anderson, M.E.4
Mitros, F.A.5
Petersen, G.M.6
Velculescu, V.E.7
Traverso, G.8
Vogelstein, B.9
-
24
-
-
52549113913
-
Bone morphogenetic protein signalling in colorectal cancer
-
Hardwick, J. C., Kodach, L. L., Offerhaus, G. J. & van den Brink, G. R. Bone morphogenetic protein signalling in colorectal cancer. Nat. Rev. Cancer. 8, 806-812 (2008).
-
(2008)
Nat. Rev. Cancer.
, vol.8
, pp. 806-812
-
-
Hardwick, J.C.1
Kodach, L.L.2
Offerhaus, G.J.3
Van Den Brink, G.R.4
-
25
-
-
33745958768
-
Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo
-
DOI 10.1016/j.ydbio.2006.04.442, PII S0012160606007226
-
Arnold, S. J., Maretto, S., Islam, A., Bikoff, E. K. & Robertson, E. J. Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo. Dev. Biol. 296, 104-118 (2006). (Pubitemid 44061758)
-
(2006)
Developmental Biology
, vol.296
, Issue.1
, pp. 104-118
-
-
Arnold, S.J.1
Maretto, S.2
Islam, A.3
Bikoff, E.K.4
Robertson, E.J.5
-
26
-
-
37549046846
-
Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice
-
Pangas, S. A. et al. Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice. Mol. Cell Biol. 28, 248-257 (2008).
-
(2008)
Mol. Cell Biol.
, vol.28
, pp. 248-257
-
-
Pangas, S.A.1
-
27
-
-
2942580631
-
Essential roles of BMPR-IA signaling in differentiation and growth of hair follicles and in skin tumorigenesis
-
DOI 10.1002/gene.20021
-
Ming, K. K., Li, A. G., Wang, X. J., Wurst, W. & Behringer, R. R. Essential roles of BMPR-IA signaling in differentiation and growth of hair follicles and in skin tumorigenesis. Genesis 39, 10-25 (2004). (Pubitemid 38738012)
-
(2004)
Genesis
, vol.39
, Issue.1
, pp. 10-25
-
-
Kwan, K.M.1
Li, A.G.2
Wang, X.-J.3
Wurst, W.4
Behringer, R.R.5
-
28
-
-
33745618456
-
Atm-deficient mice: An osteoporosis model with defective osteoblast differentiation and increased osteoclastogenesis
-
DOI 10.1093/hmg/ddl116
-
Rasheed, N., Wang, X., Niu, Q. T., Yeh, J. & Li, B. Atm-deficient mice: an osteoporosis model with defective osteoblast differentiation and increased osteoclastogenesis. Hum. Mol. Genet. 15, 1938-1948 (2006). (Pubitemid 43983268)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.12
, pp. 1938-1948
-
-
Rasheed, N.1
Wang, X.2
Niu, Q.-T.3
Yeh, J.4
Li, B.5
-
29
-
-
0034091809
-
Mice deficient in Abl are osteoporotic and have defects in osteoblast maturation
-
DOI 10.1038/73542
-
Li, B. et al. Mice deficient in Abl are osteoporotic and have defects in osteoblast maturation. Nat. Genet. 24, 304-308 (2000). (Pubitemid 30132204)
-
(2000)
Nature Genetics
, vol.24
, Issue.3
, pp. 304-308
-
-
Li, B.1
Boast, S.2
De Los Santos, K.3
Schieren, I.4
Quiroz, M.5
Teitelbaum, S.L.6
Tondravi, M.M.7
Goff, S.P.8
-
30
-
-
29944437296
-
P53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling
-
DOI 10.1083/jcb.200507106
-
Wang, X. et al. p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling. J. Cell Biol. 172, 115-125 (2006). (Pubitemid 43042634)
-
(2006)
Journal of Cell Biology
, vol.172
, Issue.1
, pp. 115-125
-
-
Wang, X.1
Kua, H.-Y.2
Hu, Y.3
Guo, K.4
Zeng, Q.5
Wu, Q.6
Ng, H.-H.7
Karsenty, G.8
De Crombrugghe, B.9
Yeh, J.10
Li, B.11
-
31
-
-
0034798285
-
ATM: Genome stability, neuronal development, and cancer cross paths
-
DOI 10.1016/S0065-230X(01)83007-4
-
Shiloh, Y. & Kastan, M. B. ATM: genome stability, neuronal development, and cancer cross paths. Adv. Cancer Res. 83, 209-254 (2001). (Pubitemid 32959266)
-
(2001)
Advances in Cancer Research
, vol.83
, pp. 209-254
-
-
Shiloh, Y.1
Kastan, M.B.2
-
32
-
-
0034576494
-
The many substrates and functions of ATM
-
Kastan, M. B. & Lim, D. S. The many substrates and functions of ATM. Nat. Rev. Mol. Cell Biol. 1, 179-186 (2000).
-
(2000)
Nat. Rev. Mol. Cell Biol.
, vol.1
, pp. 179-186
-
-
Kastan, M.B.1
Lim, D.S.2
-
33
-
-
0033621392
-
Substrate specificities and identification of putative substrates of ATM kinase family members
-
DOI 10.1074/jbc.274.53.37538
-
Kim, S. T., Lim, D. S., Canman, C. E. & Kastan, M. B. Substrate specificities and identification of putative substrates of ATM kinase family members. J. Biol. Chem. 274, 37538-37543 (1999). (Pubitemid 30026807)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.53
, pp. 37538-37543
-
-
Kim, S.-T.1
Lim, D.-S.2
Canman, C.E.3
Kastan, M.B.4
-
34
-
-
33644996932
-
Identification of phosphatases for Smad in the BMP/DPP pathway
-
Chen, H. B., Shen, J., Ip, Y. T. & Xu, L. Identification of phosphatases for Smad in the BMP/DPP pathway. Genes Dev. 20, 648-653 (2006).
-
(2006)
Genes Dev
, vol.20
, pp. 648-653
-
-
Chen, H.B.1
Shen, J.2
Ip, Y.T.3
Xu, L.4
-
35
-
-
33646950265
-
PPM1A Functions as a Smad Phosphatase to Terminate TGFβ Signaling
-
DOI 10.1016/j.cell.2006.03.044, PII S0092867406005174
-
Lin, X. et al. PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling. Cell 125, 915-928 (2006). (Pubitemid 43795197)
-
(2006)
Cell
, vol.125
, Issue.5
, pp. 915-928
-
-
Lin, X.1
Duan, X.2
Liang, Y.-Y.3
Su, Y.4
Wrighton, K.H.5
Long, J.6
Hu, M.7
Davis, C.M.8
Wang, J.9
Brunicardi, F.C.10
Shi, Y.11
Chen, Y.-G.12
Meng, A.13
Feng, X.-H.14
-
36
-
-
33846002754
-
Protein serine/threonine phosphatase PPM1A dephosphorylates Smad1 in the bone morphogenetic protein signaling pathway
-
DOI 10.1074/jbc.M605169200
-
Duan, X., Liang, Y. Y., Feng, X. H. & Lin, X. Protein serine/threonine phosphatase PPM1A dephosphorylates Smad1 in the bone morphogenetic protein signaling pathway. J. Biol. Chem. 281, 36526-36532 (2006). (Pubitemid 46042119)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.48
, pp. 36526-36532
-
-
Duan, X.1
Liang, Y.-Y.2
Feng, X.-H.3
Lin, X.4
-
37
-
-
33747044916
-
Unique players in the BMP pathway: Small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling
-
DOI 10.1073/pnas.0605133103
-
Knockaert, M., Sapkota, G., Alarcon, C., Massague, J. & Brivanlou, A. H. Unique players in the BMP pathway: small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling. Proc. Natl Acad. Sci. USA 103, 11940-11945 (2006). (Pubitemid 44215790)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.32
, pp. 11940-11945
-
-
Knockaert, M.1
Sapkota, G.2
Alarcon, C.3
Massague, J.4
Brivanlou, A.H.5
-
38
-
-
77953366105
-
Protein phosphatase magnesium-dependent 1A-mediated inhibition of BMP signaling is independent of Smad dephosphorylation
-
Kokabu, S. et al. Protein phosphatase magnesium-dependent 1A-mediated inhibition of BMP signaling is independent of Smad dephosphorylation. J. Bone Miner. Res. 25, 653-660.
-
J. Bone Miner. Res.
, vol.25
, pp. 653-660
-
-
Kokabu, S.1
-
39
-
-
31544457877
-
P53 ubiquitination: Mdm2 and beyond
-
DOI 10.1016/j.molcel.2006.01.020, PII S1097276506000402
-
Brooks, C. L. & Gu, W. p53 ubiquitination: Mdm2 and beyond. Mol. Cell 21, 307-315 (2006). (Pubitemid 43163526)
-
(2006)
Molecular Cell
, vol.21
, Issue.3
, pp. 307-315
-
-
Brooks, C.L.1
Gu, W.2
-
41
-
-
0035093737
-
DNA double-strand breaks: Signaling, repair and the cancer connection
-
DOI 10.1038/85798
-
Khanna, K. K. & Jackson, S. P. DNA double-strand breaks: signaling, repair and the cancer connection. Nat. Genet. 27, 247-254 (2001). (Pubitemid 32201842)
-
(2001)
Nature Genetics
, vol.27
, Issue.3
, pp. 247-254
-
-
Khanna, K.K.1
Jackson, S.P.2
-
42
-
-
77957654497
-
Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus
-
Mira, H. et al. Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus. Cell Stem Cell 7, 78-89 (2010).
-
(2010)
Cell Stem Cell
, vol.7
, pp. 78-89
-
-
Mira, H.1
-
43
-
-
58949102946
-
A two-step mechanism for stem cell activation during hair regeneration
-
Greco, V. et al. A two-step mechanism for stem cell activation during hair regeneration. Cell Stem Cell 4, 155-169 (2009).
-
(2009)
Cell Stem Cell
, vol.4
, pp. 155-169
-
-
Greco, V.1
-
44
-
-
6944224156
-
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-β-catenin signaling
-
DOI 10.1038/ng1430
-
He, X. C. et al. BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling. Nat. Genet. 36, 1117-1121 (2004). (Pubitemid 41184475)
-
(2004)
Nature Genetics
, vol.36
, Issue.10
, pp. 1117-1121
-
-
He, X.C.1
Zhang, J.2
Tong, W.-G.3
Tawfik, O.4
Ross, J.5
Scoville, D.H.6
Tian, Q.7
Zeng, X.8
He, X.9
Wiedemann, L.M.10
Mishina, Y.11
Li, L.12
-
45
-
-
0035736487
-
HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation
-
DOI 10.1038/ncb1101-973
-
Zhou, B. P. et al. HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation. Nat. Cell Biol. 3, 973-982 (2001). (Pubitemid 34428742)
-
(2001)
Nature Cell Biology
, vol.3
, Issue.11
, pp. 973-982
-
-
Zhou, B.P.1
Liao, Y.2
Xia, W.3
Zou, Y.4
Spohn, B.5
Hung, M.-C.6
-
46
-
-
77956392880
-
S6K1 is a multifaceted regulator of Mdm2 that connects nutrient status and DNA damage response
-
Lai, K. P. et al. S6K1 is a multifaceted regulator of Mdm2 that connects nutrient status and DNA damage response. Embo J. 29, 2994-3006 (2010).
-
(2010)
Embo J
, vol.29
, pp. 2994-3006
-
-
Lai, K.P.1
-
47
-
-
79953141390
-
Mdm2 links genotoxic stress and metabolism to p53
-
Wang, Z. & Li, B. Mdm2 links genotoxic stress and metabolism to p53. Protein Cell 1, 1063-1072 (2010).
-
(2010)
Protein Cell
, vol.1
, pp. 1063-1072
-
-
Wang, Z.1
Li, B.2
-
48
-
-
36248995245
-
Integrating Patterning Signals: Wnt/GSK3 Regulates the Duration of the BMP/Smad1 Signal
-
DOI 10.1016/j.cell.2007.09.027, PII S0092867407012160
-
Fuentealba, L. C. et al. Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal. Cell 131, 980-993 (2007). (Pubitemid 350138081)
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 980-993
-
-
Fuentealba, L.C.1
Eivers, E.2
Ikeda, A.3
Hurtado, C.4
Kuroda, H.5
Pera, E.M.6
De Robertis, E.M.7
-
49
-
-
0038274163
-
Links between tumor suppressors: P53 is required for TGF-β gene responses by cooperating with Smads
-
DOI 10.1016/S0092-8674(03)00308-8
-
Cordenonsi, M. et al. Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads. Cell 113, 301-314 (2003). (Pubitemid 36556113)
-
(2003)
Cell
, vol.113
, Issue.3
, pp. 301-314
-
-
Cordenonsi, M.1
Dupont, S.2
Maretto, S.3
Insinga, A.4
Imbriano, C.5
Piccolo, S.6
-
50
-
-
43949093106
-
P53 Regulation Orchestrates the TGF-β Response
-
DOI 10.1016/j.cell.2008.05.013, PII S0092867408006284
-
Piccolo, S. p53 regulation orchestrates the TGF-beta response. Cell 133, 767-769 (2008). (Pubitemid 351707697)
-
(2008)
Cell
, vol.133
, Issue.5
, pp. 767-769
-
-
Piccolo, S.1
-
51
-
-
33846974670
-
Integration of TGF-beta and Ras/MAPK signaling through p53 phosphorylation
-
Cordenonsi, M. et al. Integration of TGF-beta and Ras/MAPK signaling through p53 phosphorylation. Science 315, 840-843 (2007).
-
(2007)
Science
, vol.315
, pp. 840-843
-
-
Cordenonsi, M.1
-
52
-
-
43949119465
-
Ectodermal Factor Restricts Mesoderm Differentiation by Inhibiting p53
-
DOI 10.1016/j.cell.2008.03.035, PII S009286740800500X
-
Sasai, N., Yakura, R., Kamiya, D., Nakazawa, Y. & Sasai, Y. Ectodermal factor restricts mesoderm differentiation by inhibiting p53. Cell 133, 878-890 (2008). (Pubitemid 351707684)
-
(2008)
Cell
, vol.133
, Issue.5
, pp. 878-890
-
-
Sasai, N.1
Yakura, R.2
Kamiya, D.3
Nakazawa, Y.4
Sasai, Y.5
-
53
-
-
0037108674
-
Transforming growth factor-β1 mediates cellular response to DNA damage in situ
-
Ewan, K. B. et al. Transforming growth factor-beta1 mediates cellular response to DNA damage in situ. Cancer Res. 62, 5627-5631 (2002). (Pubitemid 35204711)
-
(2002)
Cancer Research
, vol.62
, Issue.20
, pp. 5627-5631
-
-
Ewan, K.B.1
Henshall-Powell, R.L.2
Ravani, S.A.3
Pajares, M.J.4
Arteaga, C.5
Warters, R.6
Akhurst, R.J.7
Barcellos-Hoff, M.H.8
-
54
-
-
33845388985
-
TGFβ1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner
-
Zhang, S. et al. TGFbeta1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner. Cell Cycle 5, 2787-2795 (2006). (Pubitemid 44901741)
-
(2006)
Cell Cycle
, vol.5
, Issue.23
, pp. 2787-2795
-
-
Zhang, S.1
Ekman, M.2
Thakur, N.3
Bu, S.4
Davoodpour, P.5
Grimsby, S.6
Tagami, S.7
Heldin, C.-H.8
Landstrom, M.9
-
55
-
-
79851482754
-
ATM/ATR and SMAD3 pathways contribute to 3-indole-induced G arrest in cancer cells and xenograft models
-
Huang, S. M., Lu, K. T. & Wang, Y. C. ATM/ATR and SMAD3 pathways contribute to 3-indole-induced G arrest in cancer cells and xenograft models. Anticancer Res. 31, 203-208.
-
Anticancer Res.
, vol.31
, pp. 203-208
-
-
Huang, S.M.1
Lu, K.T.2
Wang, Y.C.3
-
56
-
-
84857415007
-
Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses
-
Chiba, N. et al. Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses. Proc. Natl Acad. Sci. USA 109, 2760-2765 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 2760-2765
-
-
Chiba, N.1
-
57
-
-
34250189244
-
TGFβ-1 dependent fast stimulation of ATM and p53 phosphorylation following exposure to ionizing radiation does not involve TGFβ-receptor I signalling
-
DOI 10.1016/j.radonc.2007.05.013, PII S0167814007001909, Highlights from the 10th International ESTRO-Wolfsberg Meeting on Molecular Radiation Biology/Oncology 2007
-
Wiegman, E. M., Blaese, M. A., Loeffler, H., Coppes, R. P. & Rodemann, H. P. TGFbeta-1 dependent fast stimulation of ATM and p53 phosphorylation following exposure to ionizing radiation does not involve TGFbeta-receptor I signalling. Radiother. Oncol. 83, 289-295 (2007). (Pubitemid 46907986)
-
(2007)
Radiotherapy and Oncology
, vol.83
, Issue.3
, pp. 289-295
-
-
Wiegman, E.M.1
Blaese, M.A.2
Loeffler, H.3
Coppes, R.P.4
Rodemann, H.P.5
-
58
-
-
0037184969
-
Acetylation of p53 inhibits its ubiquitination by Mdm2
-
DOI 10.1074/jbc.C200578200
-
Li, M., Luo, J., Brooks, C. L. & Gu, W. Acetylation of p53 inhibits its ubiquitination by Mdm2. J. Biol. Chem. 277, 50607-50611 (2002). (Pubitemid 36042220)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.52
, pp. 50607-50611
-
-
Li, M.1
Luo, J.2
Brooks, C.L.3
Gu, W.4
|