Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 8, 2012, Pages 2760-2765

  Chiba, Naokazu ^a,b   Comaills, Valentine ^c   Shiotani, Bunsyo ^b   Takahashi, Fumiyuki ^a,b   Shimada, Toshiyuki ^a,b   Tajima, Ken ^a,b   Winokur, Daniel ^b   Hayashida, Tetsu ^a,b   Willers, Henning ^a   Brachtel, Elena ^a   Vivanco, Maria D M ^c   Haber, Daniel A ^b   Zou, Lee ^b   Maheswaran, Shyamala ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c CIC BIOGUNE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; ATR PROTEIN; HISTONE H2AX; HOMEOBOX B9 PROTEIN; HOMEODOMAIN PROTEIN; P53 BINDING PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; BREAST TUMOR; CELL STRAIN MCF 7; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; EPITHELIAL MESENCHYMAL TRANSITION; IN VITRO STUDY; IONIZING RADIATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RADIOSENSITIVITY; SINGLE STRANDED DNA BREAK; TUMOR MICROENVIRONMENT;

CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL NUCLEUS; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; ENZYME ACTIVATION; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HISTONES; HOMEODOMAIN PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PROTEIN-SERINE-THREONINE KINASES; RADIATION TOLERANCE; RADIATION, IONIZING; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; TUMOR SUPPRESSOR PROTEINS;

EID: 84857415007     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1018867108     Document Type: Article

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