Endoplasmic reticulum stress response promotes cytotoxic phenotype of CD8αβ + intraepithelial lymphocytes in a mouse model for Crohn's disease-like ileitis

Journal of Immunology

Volumn 189, Issue 3, 2012, Pages 1510-1520

  Chang, Jung Su ^a,b   Ocvirk, Soeren ^a   Berger, Emanuel ^a   Kisling, Sigrid ^a   Binder, Uli ^a   Skerra, Arne ^a   Lee, Amy S ^c   Haller, Dirk ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; CD8 ANTIGEN; CHAPERONE; GLUCOSE REGULATED PROTEIN 78; GRANZYME B; INTERLEUKIN 2; RAG2 PROTEIN; X BOX BINDING PROTEIN 1;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD8 ALPHA ALPHA+ INTRAEPITHELIAL LYMPHOCYTE; CD8 ALPHA BETA+ INTRAEPITHELIAL LYMPHOCYTE; CHROMATIN IMMUNOPRECIPITATION; CHRONIC INFLAMMATION; CONTROLLED STUDY; CROHN DISEASE LIKE ILEITIS; CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; ILEITIS; INTESTINE EPITHELIUM CELL; LAMINA PROPRIA; LYMPHOCYTE; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MOUSE; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; UNFOLDED PROTEIN RESPONSE;

ANIMALS; ANTIGENS, CD8; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CROHN DISEASE; CYTOTOXICITY, IMMUNOLOGIC; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM STRESS; EPITHELIAL CELLS; ILEITIS; IMMUNOPHENOTYPING; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC;

EID: 84864148120     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1200166     Document Type: Article

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