메뉴 건너뛰기




Volumn 1072, Issue , 2006, Pages 78-97

The intestinal microvasculature as a therapeutic target in inflammatory bowel disease

Author keywords

Alicaforsen; Angiogenesis; CCR9; Crohn's disease; Endothelial dysfunction; IBD; ICAM 1; MAdCAM 1; Microvessels; MLN02; Natalizumab; Ridogrel; Traficet EN; Ulcerative colitis

Indexed keywords

ALICAFORSEN; CHEMOKINE RECEPTOR CCR9; CYTOKINE; INTERCELLULAR ADHESION MOLECULE 1; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; NATALIZUMAB; RIDOGREL;

EID: 33749016804     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1326.003     Document Type: Conference Paper
Times cited : (69)

References (142)
  • 1
    • 0031978507 scopus 로고    scopus 로고
    • Leukocyte-endothelial cell interactions: Molecular mechanisms and implications in gastrointestinal disease
    • PANES, J. & D.N. GRANGER. 1998. Leukocyte-endothelial cell interactions: molecular mechanisms and implications in gastrointestinal disease. Gastroenterology 114: 1066-1190.
    • (1998) Gastroenterology , vol.114 , pp. 1066-1190
    • Panes, J.1    Granger, D.N.2
  • 2
    • 0027419790 scopus 로고
    • Cytokines and animal models: A combined path to inflammatory bowel disease pathogenesis
    • FIOCCHI, C. 1993. Cytokines and animal models: a combined path to inflammatory bowel disease pathogenesis. Gastroenterology 104: 1202-1205.
    • (1993) Gastroenterology , vol.104 , pp. 1202-1205
    • Fiocchi, C.1
  • 3
    • 0027409322 scopus 로고
    • Localization of intestinal interleukin 1 activity and protein and gene expression to lamina propria cells
    • YOUNGMAN, K.R. et al. 1993. Localization of intestinal interleukin 1 activity and protein and gene expression to lamina propria cells. Gastroenterology 104: 749-758.
    • (1993) Gastroenterology , vol.104 , pp. 749-758
    • Youngman, K.R.1
  • 4
    • 0031004878 scopus 로고    scopus 로고
    • Enhanced leukocyte binding by intestinal microvascular endothelial cells in inflammatory bowel disease
    • BINION, D.G. et al. 1997. Enhanced leukocyte binding by intestinal microvascular endothelial cells in inflammatory bowel disease. Gastroenterology 112: 1895-1907.
    • (1997) Gastroenterology , vol.112 , pp. 1895-1907
    • Binion, D.G.1
  • 5
    • 0032576359 scopus 로고    scopus 로고
    • Acquired increase in leucocyte binding by intestinal microvascular endothelium in inflammatory bowel disease
    • BINION, D.G. et al. 1998. Acquired increase in leucocyte binding by intestinal microvascular endothelium in inflammatory bowel disease. Lancet 352: 1742-1746.
    • (1998) Lancet , vol.352 , pp. 1742-1746
    • Binion, D.G.1
  • 6
    • 0034333259 scopus 로고    scopus 로고
    • Deficient iNOS in inflammatory bowel disease intestinal microvascular endothelial cells results in increased leukocyte adhesion
    • BINION, D.G. et al. 2000. Deficient iNOS in inflammatory bowel disease intestinal microvascular endothelial cells results in increased leukocyte adhesion. Free Radic. Biol. Med. 29: 881-888.
    • (2000) Free Radic. Biol. Med. , vol.29 , pp. 881-888
    • Binion, D.G.1
  • 7
    • 0028158113 scopus 로고
    • Aberrant binding of lamina propria lymphocytes to vascular endothelium in inflammatory bowel diseases
    • SALMI, M. et al. 1994. Aberrant binding of lamina propria lymphocytes to vascular endothelium in inflammatory bowel diseases. Gastroenterology 106: 596-605.
    • (1994) Gastroenterology , vol.106 , pp. 596-605
    • Salmi, M.1
  • 8
    • 0029089753 scopus 로고
    • Peripheral monocyte and naive T-cell recruitment and activation in Crohn's disease
    • BURGIO, V.L. et al. 1995. Peripheral monocyte and naive T-cell recruitment and activation in Crohn's disease. Gastroenterology 109: 1029-1038.
    • (1995) Gastroenterology , vol.109 , pp. 1029-1038
    • Burgio, V.L.1
  • 9
    • 0035214691 scopus 로고    scopus 로고
    • Antibody blockade of ICAM-1 and VCAM-1 ameliorates inflammation in the SAMP-1/Yit adoptive transfer model of Crohn's disease in mice
    • BURNS, R.C. et al. 2001. Antibody blockade of ICAM-1 and VCAM-1 ameliorates inflammation in the SAMP-1/Yit adoptive transfer model of Crohn's disease in mice. Gastroenterology 121: 1428-1436.
    • (2001) Gastroenterology , vol.121 , pp. 1428-1436
    • Burns, R.C.1
  • 10
    • 13544259959 scopus 로고    scopus 로고
    • L-selectin, alpha 4 beta 1, and alpha 4 beta 7 integrins participate in CD4+ T cell recruitment to chronically inflamed small intestine
    • RIVERA-NIEVES, J. et al. 2005. L-selectin, alpha 4 beta 1, and alpha 4 beta 7 integrins participate in CD4+ T cell recruitment to chronically inflamed small intestine. J. Immunol. 174: 2343-2352.
    • (2005) J. Immunol. , vol.174 , pp. 2343-2352
    • Rivera-Nieves, J.1
  • 11
    • 2442519018 scopus 로고    scopus 로고
    • Selectins in T-cell recruitment to non-lymphoid tissues and sites of inflammation
    • LEY, K. & G.S. KANSAS. 2004. Selectins in T-cell recruitment to non-lymphoid tissues and sites of inflammation. Nat. Rev. Immunol. 4: 325-335.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 325-335
    • Ley, K.1    Kansas, G.S.2
  • 12
    • 30044445549 scopus 로고    scopus 로고
    • Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn's disease
    • BACHMANN, C. et al. 2006. Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn's disease. Gastroenterology 130: 8-16.
    • (2006) Gastroenterology , vol.130 , pp. 8-16
    • Bachmann, C.1
  • 13
    • 0029095952 scopus 로고
    • The selectins: Vascular adhesion molecules
    • TEDDER, T.F. et al. 1995. The selectins: vascular adhesion molecules. FASEB J. 9: 866-873.
    • (1995) FASEB J. , vol.9 , pp. 866-873
    • Tedder, T.F.1
  • 14
    • 0029042710 scopus 로고
    • L-selectin-deficient mice have impaired leukocyte recruitment into inflammatory sites
    • TEDDER, T.F., D.A. STEEBER & P. PIZCUETA 1995. L-selectin-deficient mice have impaired leukocyte recruitment into inflammatory sites. J. Exp. Med. 181: 2259-2264.
    • (1995) J. Exp. Med. , vol.181 , pp. 2259-2264
    • Tedder, T.F.1    Steeber, D.A.2    Pizcueta, P.3
  • 15
    • 0029558032 scopus 로고
    • Regional differences in constitutive and induced ICAM-1 expression in vivo
    • PANES, J. et al. 1995. Regional differences in constitutive and induced ICAM-1 expression in vivo. Am. J. Physiol. 269(6 Pt 2): H1955-H1964.
    • (1995) Am. J. Physiol. , vol.269 , Issue.6 PART 2
    • Panes, J.1
  • 16
    • 0027248939 scopus 로고
    • Attenuation of colitis in the cotton-top tamarin by anti-alpha 4 integrin monoclonal antibody
    • PODOLSKY, D.K. et al. 1993. Attenuation of colitis in the cotton-top tamarin by anti-alpha 4 integrin monoclonal antibody. J. Clin. Invest. 92: 372-380.
    • (1993) J. Clin. Invest. , vol.92 , pp. 372-380
    • Podolsky, D.K.1
  • 17
    • 0026660635 scopus 로고
    • Expression of vascular adhesion molecules in inflammatory bowel disease
    • KOIZUMI, M. et al. 1992. Expression of vascular adhesion molecules in inflammatory bowel disease. Gastroenterology 103: 840-847.
    • (1992) Gastroenterology , vol.103 , pp. 840-847
    • Koizumi, M.1
  • 18
    • 0033063325 scopus 로고    scopus 로고
    • VCAM-I and ICAM-I mediate leukocyte-endothelial cell adhesion in rat experimental colitis
    • SANS, M. et al. 1999. VCAM-I and ICAM-I mediate leukocyte-endothelial cell adhesion in rat experimental colitis. Gastroenterology 116: 874-883.
    • (1999) Gastroenterology , vol.116 , pp. 874-883
    • Sans, M.1
  • 19
    • 0033783628 scopus 로고    scopus 로고
    • VCAM-1, but not ICAM-1 or MAdCAM-1, immunoblockade ameliorates DSS-induced colitis in mice
    • SORIANO, A. et al. 2000. VCAM-1, but not ICAM-1 or MAdCAM-1, immunoblockade ameliorates DSS-induced colitis in mice. Lab. Invest. 80: 1541-1551.
    • (2000) Lab. Invest. , vol.80 , pp. 1541-1551
    • Soriano, A.1
  • 20
    • 0030885492 scopus 로고    scopus 로고
    • Proteasome inhibition attenuates nitric oxide synthase expression, VCAM-1 transcription and the development of chronic colitis
    • CONNER, E.M. et al. 1997. Proteasome inhibition attenuates nitric oxide synthase expression, VCAM-1 transcription and the development of chronic colitis. J. Pharmacol. Exp. Ther. 282: 1615-1622.
    • (1997) J. Pharmacol. Exp. Ther. , vol.282 , pp. 1615-1622
    • Conner, E.M.1
  • 21
    • 18244429498 scopus 로고    scopus 로고
    • Cytokine and endothelial cell adhesion molecule expression in interleukin-10-deficient mice
    • KAWACHI, S. et al. 2000. Cytokine and endothelial cell adhesion molecule expression in interleukin-10-deficient mice. Am. J. Physiol. Gastrointest. Liver Physiol. 278: G734-G743.
    • (2000) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.278
    • Kawachi, S.1
  • 22
    • 0036066284 scopus 로고    scopus 로고
    • Antiadhesion molecule therapy in inflammatory bowel disease
    • VAN ASSCHE, G. & P. RUTGEERTS. 2002. Antiadhesion molecule therapy in inflammatory bowel disease. Inflamm. Bowel Dis. 8: 291-300.
    • (2002) Inflamm. Bowel Dis. , vol.8 , pp. 291-300
    • Van Assche, G.1    Rutgeerts, P.2
  • 23
    • 0022574146 scopus 로고
    • Induction by IL 1 and interferon-gamma: Tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1)
    • DUSTIN, M.L. et al. 1986. Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J. Immunol. 137: 245-254.
    • (1986) J. Immunol. , vol.137 , pp. 245-254
    • Dustin, M.L.1
  • 24
    • 0022453692 scopus 로고
    • A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1
    • ROTHLEIN, R. et al. 1986. A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1. J. Immunol. 137: 1270-1274.
    • (1986) J. Immunol. , vol.137 , pp. 1270-1274
    • Rothlein, R.1
  • 25
    • 0023644247 scopus 로고
    • Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)
    • MARLIN, S.D. & T.A. SPRINGER. 1987. Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1). Cell 51: 813-819.
    • (1987) Cell , vol.51 , pp. 813-819
    • Marlin, S.D.1    Springer, T.A.2
  • 26
    • 0025678813 scopus 로고
    • ICAM-1 (CD54): A counter-receptor for Mac-1 (CD11b/CD18)
    • DIAMOND, M.S. et al. 1990. ICAM-1 (CD54): a counter-receptor for Mac-1 (CD11b/CD18). J. Cell. Biol. 111(6 Pt 2): 3129-3139.
    • (1990) J. Cell. Biol. , vol.111 , Issue.6 PART 2 , pp. 3129-3139
    • Diamond, M.S.1
  • 27
    • 0028355977 scopus 로고
    • Treatment of refractory rheumatoid arthritis with a monoclonal antibody to intercellular adhesion molecule 1
    • KAVANAUGH, A.F. et al. 1994. Treatment of refractory rheumatoid arthritis with a monoclonal antibody to intercellular adhesion molecule 1. Arthritis Rheum. 37: 992-999.
    • (1994) Arthritis Rheum. , vol.37 , pp. 992-999
    • Kavanaugh, A.F.1
  • 28
    • 0028220670 scopus 로고
    • Inhibition of endothelial cell adhesion molecule expression with antisense oligonucleotides
    • BENNETT, C.F. et al. 1994. Inhibition of endothelial cell adhesion molecule expression with antisense oligonucleotides. J. Immunol. 152: 3530-3540.
    • (1994) J. Immunol. , vol.152 , pp. 3530-3540
    • Bennett, C.F.1
  • 29
    • 0028077713 scopus 로고
    • Cationic lipid is not required for uptake and selective inhibitory activity of ICAM-1 phosphorothioate antisense oligonucleotides in keratinocytes
    • NESTLE, F.O. et al. 1994. Cationic lipid is not required for uptake and selective inhibitory activity of ICAM-1 phosphorothioate antisense oligonucleotides in keratinocytes. J. Invest. Dermatol. 103: 569-575.
    • (1994) J. Invest. Dermatol. , vol.103 , pp. 569-575
    • Nestle, F.O.1
  • 30
    • 0026052924 scopus 로고
    • Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms
    • CHIANG, M.Y. et al. 1991. Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms. J. Biol. Chem. 266: 18162-18171.
    • (1991) J. Biol. Chem. , vol.266 , pp. 18162-18171
    • Chiang, M.Y.1
  • 31
    • 0026048056 scopus 로고
    • Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection
    • HOKE, G.D. et al. 1991. Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection. Nucleic Acids Res. 19: 5743-5748.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 5743-5748
    • Hoke, G.D.1
  • 32
    • 0022780091 scopus 로고
    • Oligodeoxynucleotide stability in subcellular extracts and culture media
    • WICKSTROM, E. 1986. Oligodeoxynucleotide stability in subcellular extracts and culture media. J. Biochem. Biophys. Methods 13: 97-102.
    • (1986) J. Biochem. Biophys. Methods , vol.13 , pp. 97-102
    • Wickstrom, E.1
  • 33
    • 0031782392 scopus 로고    scopus 로고
    • A placebo-controlled trial of ICAM-1 antisense oligonucleotide in the treatment of Crohn's disease
    • YACYSHYN, B.R. et al. 1998. A placebo-controlled trial of ICAM-1 antisense oligonucleotide in the treatment of Crohn's disease. Gastroenterology 114: 1133-1142.
    • (1998) Gastroenterology , vol.114 , pp. 1133-1142
    • Yacyshyn, B.R.1
  • 34
    • 0035045185 scopus 로고    scopus 로고
    • Absence of efficacy of subcutaneous antisense ICAM-1 treatment of chronic active Crohn's disease
    • SCHREIBER, S. et al. 2001. Absence of efficacy of subcutaneous antisense ICAM-1 treatment of chronic active Crohn's disease. Gastroenterology 120: 1339-1346.
    • (2001) Gastroenterology , vol.120 , pp. 1339-1346
    • Schreiber, S.1
  • 35
    • 7244252832 scopus 로고    scopus 로고
    • A randomised, controlled, double blind, escalating dose study of alicaforsen enema in active ulcerative colitis
    • VAN DEVENTER, S.J., J.A. TAMI & M.K. WEDEL. 2004. A randomised, controlled, double blind, escalating dose study of alicaforsen enema in active ulcerative colitis. Gut 53: 1646-1651.
    • (2004) Gut , vol.53 , pp. 1646-1651
    • Van Deventer, S.J.1    Tami, J.A.2    Wedel, M.K.3
  • 36
    • 0028360991 scopus 로고
    • Trefoil peptides promote epithelial migration through a transforming growth factor beta-independent pathway
    • DIGNASS, A. et al. 1994. Trefoil peptides promote epithelial migration through a transforming growth factor beta-independent pathway. J. Clin. Invest. 94: 376-383.
    • (1994) J. Clin. Invest. , vol.94 , pp. 376-383
    • Dignass, A.1
  • 37
    • 0344496250 scopus 로고    scopus 로고
    • Novel approaches to treating inflammatory bowel disease: Targeting alpha-4 integrin
    • SANDBORN, W.J. & T.A. YEDNOCK. 2003. Novel approaches to treating inflammatory bowel disease: targeting alpha-4 integrin. Am. J. Gastroenterol. 98: 2372-2382.
    • (2003) Am. J. Gastroenterol. , vol.98 , pp. 2372-2382
    • Sandborn, W.J.1    Yednock, T.A.2
  • 38
    • 0037413468 scopus 로고    scopus 로고
    • Natalizumab for active Crohn's disease
    • GHOSH, S. et al. 2003. Natalizumab for active Crohn's disease. N. Engl. J. Med. 348: 24-32.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 24-32
    • Ghosh, S.1
  • 39
    • 27644441529 scopus 로고    scopus 로고
    • Natalizumab induction and maintenance therapy for Crohn's disease
    • SANDBORN, W.J. et al. 2005. Natalizumab induction and maintenance therapy for Crohn's disease. N. Engl. J. Med. 353: 1912-1925.
    • (2005) N. Engl. J. Med. , vol.353 , pp. 1912-1925
    • Sandborn, W.J.1
  • 40
    • 20444469332 scopus 로고    scopus 로고
    • Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin
    • FEAGAN, B.G. et al. 2005. Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin. N. Engl. J. Med. 352: 2499-2507.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 2499-2507
    • Feagan, B.G.1
  • 41
    • 0034326706 scopus 로고    scopus 로고
    • The role of chemokines and chemokine receptors in mucosal inflammation
    • PAPADAKIS, K.A. & S.R. TARGAN. 2000. The role of chemokines and chemokine receptors in mucosal inflammation. Inflamm. Bowel Dis. 6: 303-313.
    • (2000) Inflamm. Bowel Dis. , vol.6 , pp. 303-313
    • Papadakis, K.A.1    Targan, S.R.2
  • 42
    • 2142822265 scopus 로고    scopus 로고
    • Chemokines in inflammatory bowel disease
    • PAPADAKIS, K.A. 2004. Chemokines in inflammatory bowel disease. Curr. Allergy Asthma Rep. 4: 83-89.
    • (2004) Curr. Allergy Asthma Rep. , vol.4 , pp. 83-89
    • Papadakis, K.A.1
  • 43
    • 0038206634 scopus 로고    scopus 로고
    • CC chemokine receptor 9 expression defines a subset of peripheral blood lymphocytes with mucosal T cell phenotype and Th1 or T-regulatory 1 cytokine profile
    • PAPADAKIS, K.A. et al. 2003. CC chemokine receptor 9 expression defines a subset of peripheral blood lymphocytes with mucosal T cell phenotype and Th1 or T-regulatory 1 cytokine profile. J. Immunol. 171: 159-165.
    • (2003) J. Immunol. , vol.171 , pp. 159-165
    • Papadakis, K.A.1
  • 44
    • 0034899072 scopus 로고    scopus 로고
    • CCR9-positive lymphocytes and thymus-expressed chemokine distinguish small bowel from colonic Crohn's disease
    • PAPADAKIS, K.A. et al. 2001. CCR9-positive lymphocytes and thymus-expressed chemokine distinguish small bowel from colonic Crohn's disease. Gastroenterology 121: 246-254.
    • (2001) Gastroenterology , vol.121 , pp. 246-254
    • Papadakis, K.A.1
  • 45
    • 0034327830 scopus 로고    scopus 로고
    • The role of thymus-expressed chemokine and its receptor CCR9 on lymphocytes in the regional specialization of the mucosal immune system
    • PAPADAKIS, K.A. et al. 2000. The role of thymus-expressed chemokine and its receptor CCR9 on lymphocytes in the regional specialization of the mucosal immune system. J. Immunol. 165: 5069-5076.
    • (2000) J. Immunol. , vol.165 , pp. 5069-5076
    • Papadakis, K.A.1
  • 46
    • 5644271509 scopus 로고    scopus 로고
    • CC chemokine ligand 25 enhances resistance to apoptosis in CD4+ T cells from patients with T-cell lineage acute and chronic lymphocytic leukemia by means of living activation
    • QIUPING, Z. et al. 2004. CC chemokine ligand 25 enhances resistance to apoptosis in CD4+ T cells from patients with T-cell lineage acute and chronic lymphocytic leukemia by means of living activation. Cancer Res. 64: 7579-7587.
    • (2004) Cancer Res. , vol.64 , pp. 7579-7587
    • Qiuping, Z.1
  • 47
    • 33749004373 scopus 로고    scopus 로고
    • Cc chemokine receptor 9 (ccr9) antagonist ameliorates experimental ileitis and colitis
    • ZHENG WEI, L.E., T. BAUMGART, W. RUBAS, et al. 2005. Cc chemokine receptor 9 (ccr9) antagonist ameliorates experimental ileitis and colitis. Gastroenterology 128: A-204-205.
    • (2005) Gastroenterology , vol.128 , pp. 204-205
    • Zheng Wei, L.E.1    Baumgart, T.2    Rubas, W.3
  • 48
    • 0032708292 scopus 로고    scopus 로고
    • Remodeling of vascular wall in Crohn's disease
    • FUNAYAMA, Y. et al. 1999. Remodeling of vascular wall in Crohn's disease. Dig. Dis. Sci. 44: 2319-2323.
    • (1999) Dig. Dis. Sci. , vol.44 , pp. 2319-2323
    • Funayama, Y.1
  • 49
    • 0025806992 scopus 로고
    • Granulomatous vasculitis in Crohn's disease
    • WAKEFIELD, A.J. et al. 1991. Granulomatous vasculitis in Crohn's disease. Gastroenterology 100(5 Pt 1): 1279-1287.
    • (1991) Gastroenterology , vol.100 , Issue.5 PART 1 , pp. 1279-1287
    • Wakefield, A.J.1
  • 50
    • 0017342254 scopus 로고
    • Regional intestinal blood flow in ulcerative colitis and Crohn's disease
    • HULTEN, L. et al. 1977. Regional intestinal blood flow in ulcerative colitis and Crohn's disease. Gastroenterology 72: 388-396.
    • (1977) Gastroenterology , vol.72 , pp. 388-396
    • Hulten, L.1
  • 51
    • 0027380474 scopus 로고
    • Neoterminal ileal blood flow after ileocolonic resection for Crohn's disease
    • ANGERSON, W.J. et al. 1993. Neoterminal ileal blood flow after ileocolonic resection for Crohn's disease. Gut 34: 1531-1534.
    • (1993) Gut , vol.34 , pp. 1531-1534
    • Angerson, W.J.1
  • 52
    • 0030827143 scopus 로고    scopus 로고
    • Assessment of blood flow in the small intestine by laser Doppler flowmetry: Comparison of healthy small intestine and small intestine in Crohn's disease
    • TATEISHI, S.,S. ARIMA & K. FUTAMI. 1997. Assessment of blood flow in the small intestine by laser Doppler flowmetry: comparison of healthy small intestine and small intestine in Crohn's disease. J. Gastroenterol. 32: 457-463.
    • (1997) J. Gastroenterol. , vol.32 , pp. 457-463
    • Tateishi, S.1    Arima, S.2    Futami, K.3
  • 53
    • 0342991848 scopus 로고    scopus 로고
    • Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease
    • BOGER, R.H. et al. 1998. Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease. J. Am. Coll. Cardiol. 32: 1336-1344.
    • (1998) J. Am. Coll. Cardiol. , vol.32 , pp. 1336-1344
    • Boger, R.H.1
  • 54
    • 0030276557 scopus 로고    scopus 로고
    • The non-healing leg ulcer: Peripheral vascular disease, chronic venous insufficiency, and ischemic vasculitis
    • KERSTEIN, M.D. 1996. The non-healing leg ulcer: peripheral vascular disease, chronic venous insufficiency, and ischemic vasculitis. Ostomy Wound Manage. 42(10A Suppl): 19S-35S.
    • (1996) Ostomy Wound Manage. , vol.42 , Issue.10 A SUPPL.
    • Kerstein, M.D.1
  • 55
    • 0036942407 scopus 로고    scopus 로고
    • Intermittent compression pump for nonhealing wounds in patients with limb ischemia. The Mayo Clinic experience (1998-2000)
    • MONTORI, V.M. et al. 2002. Intermittent compression pump for nonhealing wounds in patients with limb ischemia. The Mayo Clinic experience (1998-2000). Int. Angiol. 21: 360-366.
    • (2002) Int. Angiol. , vol.21 , pp. 360-366
    • Montori, V.M.1
  • 56
    • 0026549720 scopus 로고
    • Aetiology of diabetic foot ulceration: A role for the microcirculation?
    • FLYNN, M.D. & J.E. TOOKE. 1992. Aetiology of diabetic foot ulceration: a role for the microcirculation? Diabet. Med. 9: 320-329.
    • (1992) Diabet. Med. , vol.9 , pp. 320-329
    • Flynn, M.D.1    Tooke, J.E.2
  • 57
    • 0031939017 scopus 로고    scopus 로고
    • Endothelial dysfunction and the expression of endothelial nitric oxide synthetase in diabetic neuropathy, vascular disease, and foot ulceration
    • VEVES, A. et al. 1998. Endothelial dysfunction and the expression of endothelial nitric oxide synthetase in diabetic neuropathy, vascular disease, and foot ulceration. Diabetes 47: 457-463.
    • (1998) Diabetes , vol.47 , pp. 457-463
    • Veves, A.1
  • 58
    • 0037900056 scopus 로고    scopus 로고
    • Pathophysiological implications of insulin resistance on vascular endothelial function
    • WHEATCROFT, S.B. et al. 2003. Pathophysiological implications of insulin resistance on vascular endothelial function. Diabet. Med. 20: 255-268.
    • (2003) Diabet. Med. , vol.20 , pp. 255-268
    • Wheatcroft, S.B.1
  • 59
    • 0038449206 scopus 로고    scopus 로고
    • Acquired microvascular dysfunction in inflammatory bowel disease: Loss of nitric oxide-mediated vasodilation
    • HATOUM, O.A. et al. 2003. Acquired microvascular dysfunction in inflammatory bowel disease: loss of nitric oxide-mediated vasodilation. Gastroenterology 125: 58-69.
    • (2003) Gastroenterology , vol.125 , pp. 58-69
    • Hatoum, O.A.1
  • 60
    • 26044451963 scopus 로고    scopus 로고
    • Colonic blood flow responses in experimental colitis: Time course and underlying mechanisms
    • MORI, M. et al. 2005. Colonic blood flow responses in experimental colitis: time course and underlying mechanisms. Am. J. Physiol. Gastrointest. Liver Physiol. 289: G1024-G1029.
    • (2005) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.289
    • Mori, M.1
  • 61
    • 0018417916 scopus 로고
    • Crohn's disease: A scanning electron microscopic study
    • DVORAK, A.M., A.B. CONNELL & G.R. DICKERSIN. 1979. Crohn's disease: a scanning electron microscopic study. Hum. Pathol. 10: 165-177.
    • (1979) Hum. Pathol. , vol.10 , pp. 165-177
    • Dvorak, A.M.1    Connell, A.B.2    Dickersin, G.R.3
  • 62
    • 0018596460 scopus 로고
    • Crohn's disease: Electron microscopic studies
    • DVORAK, A.M. & G.R. DICKERSIN. 1979. Crohn's disease: electron microscopic studies. Pathol. Annu. 14(Pt 2): 259-306.
    • (1979) Pathol. Annu. , vol.14 , Issue.PART 2 , pp. 259-306
    • Dvorak, A.M.1    Dickersin, G.R.2
  • 63
    • 0029080027 scopus 로고
    • Isolation and longterm culture of human intestinal microvascular endothelial cells
    • HARALDSEN, G. et al. 1995. Isolation and longterm culture of human intestinal microvascular endothelial cells. Gut 37: 225-234.
    • (1995) Gut , vol.37 , pp. 225-234
    • Haraldsen, G.1
  • 64
    • 0030001831 scopus 로고    scopus 로고
    • Cytokine-regulated expression of E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in human microvascular endothelial cells
    • HARALDSEN, G. et al. 1996. Cytokine-regulated expression of E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in human microvascular endothelial cells. J. Immunol. 156: 2558-2565.
    • (1996) J. Immunol. , vol.156 , pp. 2558-2565
    • Haraldsen, G.1
  • 65
    • 0031659995 scopus 로고    scopus 로고
    • iNOS expression in human intestinal microvascular endothelial cells inhibits leukocyte adhesion
    • BINION, D.G. et al. 1998. iNOS expression in human intestinal microvascular endothelial cells inhibits leukocyte adhesion. Am. J. Physiol. 275(3 Pt 1): G592-G603.
    • (1998) Am. J. Physiol. , vol.275 , Issue.3 PART 1
    • Binion, D.G.1
  • 66
    • 0025731835 scopus 로고
    • Nitric oxide: An endogenous modulator of leukocyte adhesion
    • KUBES, P., M. SUZUKI & D.N. GRANGER. 1991. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc. Natl. Acad. Sci. USA 88: 4651-4655.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4651-4655
    • Kubes, P.1    Suzuki, M.2    Granger, D.N.3
  • 67
    • 0034253943 scopus 로고    scopus 로고
    • Nitric oxide and intestinal inflammation
    • KUBES, P. & D.M. MCCAFFERTY. 2000. Nitric oxide and intestinal inflammation. Am. J. Med. 109: 150-158.
    • (2000) Am. J. Med. , vol.109 , pp. 150-158
    • Kubes, P.1    Mccafferty, D.M.2
  • 69
    • 0027984808 scopus 로고
    • Endothelins: Molecular biology, biochemistry, pharmacology, physiology, and pathophysiology
    • RUBANYI, G.M. & M.A. POLOKOFF. 1994. Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacol. Rev. 46: 325-415.
    • (1994) Pharmacol. Rev. , vol.46 , pp. 325-415
    • Rubanyi, G.M.1    Polokoff, M.A.2
  • 70
    • 0026557257 scopus 로고
    • High endothelin-1 immunoreactivity in Crohn's disease and ulcerative colitis
    • MURCH, S.H. et al. 1992. High endothelin-1 immunoreactivity in Crohn's disease and ulcerative colitis. Lancet 339: 381-385.
    • (1992) Lancet , vol.339 , pp. 381-385
    • Murch, S.H.1
  • 71
    • 0033072530 scopus 로고    scopus 로고
    • Growth factors in inflammatory bowel disease. Inflamm
    • BECK, P.L. & D.K. PODOLSKY. 1999. Growth factors in inflammatory bowel disease. Inflamm. Bowel Dis. 5: 44-60.
    • (1999) Bowel Dis. , vol.5 , pp. 44-60
    • Beck, P.L.1    Podolsky, D.K.2
  • 72
    • 0028934099 scopus 로고
    • Is proximal demarcation of ulcerative colitis determined by the territory of the inferior mesenteric artery?
    • HAMILTON, M.I. et al. 1995. Is proximal demarcation of ulcerative colitis determined by the territory of the inferior mesenteric artery? Lancet 345: 688-690.
    • (1995) Lancet , vol.345 , pp. 688-690
    • Hamilton, M.I.1
  • 73
    • 0024445939 scopus 로고
    • Pathogenesis of Crohn's disease: Multifocal gastrointestinal infarction
    • WAKEFIELD, A.J. et al. 1989. Pathogenesis of Crohn's disease: multifocal gastrointestinal infarction. Lancet 2: 1057-1062.
    • (1989) Lancet , vol.2 , pp. 1057-1062
    • Wakefield, A.J.1
  • 74
    • 0033975333 scopus 로고    scopus 로고
    • Established and emerging biological activity markers of inflammatory bowel disease
    • NIELSEN, O.H. et al. 2000. Established and emerging biological activity markers of inflammatory bowel disease. Am. J. Gastroenterol 95: 359-367.
    • (2000) Am. J. Gastroenterol , vol.95 , pp. 359-367
    • Nielsen, O.H.1
  • 75
    • 0028236232 scopus 로고
    • Tumor necrosis factor alpha-producing cells in the intestinal mucosa of children with inflammatory bowel disease
    • BREESE, E.J. et al. 1994. Tumor necrosis factor alpha-producing cells in the intestinal mucosa of children with inflammatory bowel disease. Gastroenterology 106: 1455-1466.
    • (1994) Gastroenterology , vol.106 , pp. 1455-1466
    • Breese, E.J.1
  • 76
    • 0028793499 scopus 로고
    • Endothelin-1 mediates coronary vasoconstriction caused by exogenous and endogenous cytokines
    • KLEMM, P. et al. 1995. Endothelin-1 mediates coronary vasoconstriction caused by exogenous and endogenous cytokines. J. Cardiovasc. Pharmacol. 26(Suppl 3): S419-S421.
    • (1995) J. Cardiovasc. Pharmacol. , vol.26 , Issue.SUPPL. 3
    • Klemm, P.1
  • 77
    • 0030041401 scopus 로고    scopus 로고
    • What turns on the endothelins?
    • WARNER, T.D. & P. KLEMM. 1996. What turns on the endothelins? Inflamm. Res. 45: 51-53.
    • (1996) Inflamm. Res. , vol.45 , pp. 51-53
    • Warner, T.D.1    Klemm, P.2
  • 78
    • 0026594285 scopus 로고
    • Colonic endothelin-1 immunoreactivity in active ulcerative colitis
    • RACHMILEWITZ, D. et al. 1992. Colonic endothelin-1 immunoreactivity in active ulcerative colitis. Lancet 339: 1062.
    • (1992) Lancet , vol.339 , pp. 1062
    • Rachmilewitz, D.1
  • 79
    • 0016748441 scopus 로고
    • Thromboxanes: A new group of biologically active compounds derived from prostaglandin endoperoxides
    • HAMBERG, M., J. SVENSSON & B. SAMUELSSON. 1975. Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. Proc. Natl. Acad. Sci. USA 72: 2994-2998.
    • (1975) Proc. Natl. Acad. Sci. USA , vol.72 , pp. 2994-2998
    • Hamberg, M.1    Svensson, J.2    Samuelsson, B.3
  • 80
    • 0027303354 scopus 로고
    • Inflammatory mediator changes in cotton-top tamarins (CTT) after SC-41930 anti-colitic therapy
    • regular weight
    • CLAPP, N. et al. 1993. Inflammatory mediator changes in cotton-top tamarins (CTT) after SC-41930 anti-colitic therapy. Agents Actions 39(Spec. No. regular weight): C8-C10.
    • (1993) Agents Actions , vol.39 , Issue.SPEC. NO.
    • Clapp, N.1
  • 81
    • 0027201188 scopus 로고
    • Anti-colitic efficacy of SC-41930 in colitic cotton-top tamarins
    • regular weight
    • CLAPP, N. et al. 1993. Anti-colitic efficacy of SC-41930 in colitic cotton-top tamarins. Agents Actions 39(Spec. No. regular weight): C36-C38.
    • (1993) Agents Actions , vol.39 , Issue.SPEC. NO.
    • Clapp, N.1
  • 82
    • 0021965707 scopus 로고
    • Metabolism of arachidonic acid in acetic acid colitis in rats: Similarity to human inflammatory bowel disease
    • SHARON, P & W.F. STENSON. 1985. Metabolism of arachidonic acid in acetic acid colitis in rats: similarity to human inflammatory bowel disease. Gastroenterology 88(1 Pt 1): 55-63.
    • (1985) Gastroenterology , vol.88 , Issue.1 PART 1 , pp. 55-63
    • Sharon, P.1    Stenson, W.F.2
  • 83
    • 0025095341 scopus 로고
    • Participation of thromboxane and other eicosanoid synthesis in the course of experimental inflammatory colitis
    • VILASECA, J. et al. 1990. Participation of thromboxane and other eicosanoid synthesis in the course of experimental inflammatory colitis. Gastroenterology 98: 269-277.
    • (1990) Gastroenterology , vol.98 , pp. 269-277
    • Vilaseca, J.1
  • 84
    • 0026516115 scopus 로고
    • Effect of ingestion of eicosapentaenoic acid ethyl ester on carrageenan-induced colitis in guinea pigs
    • KITSUKAWA, Y. et al. 1992. Effect of ingestion of eicosapentaenoic acid ethyl ester on carrageenan-induced colitis in guinea pigs. Gastroenterology 102: 1859-1866.
    • (1992) Gastroenterology , vol.102 , pp. 1859-1866
    • Kitsukawa, Y.1
  • 85
    • 0020612014 scopus 로고
    • Prostanoid synthesis by cultured intestinal epithelial and mononuclear cells in inflammatory bowel disease
    • ZIFRONI, A. et al. 1983. Prostanoid synthesis by cultured intestinal epithelial and mononuclear cells in inflammatory bowel disease. Gut 24: 659-664.
    • (1983) Gut , vol.24 , pp. 659-664
    • Zifroni, A.1
  • 86
    • 0027293793 scopus 로고
    • Review article: Thromboxanes in inflammatory bowel disease: Pathogenic and therapeutic implications
    • RAMPTON, D.S. & C.E. COLLINS. 1993. Review article: thromboxanes in inflammatory bowel disease: pathogenic and therapeutic implications. Aliment. Pharmacol. Ther. 7: 357-367.
    • (1993) Aliment. Pharmacol. Ther. , vol.7 , pp. 357-367
    • Rampton, D.S.1    Collins, C.E.2
  • 88
    • 0020696959 scopus 로고
    • Stimulation and inhibition of prostacyclin formation in the gastric mucosa and ileum in vitro by anti-inflammatory agents
    • BOUGHTON-SMITH, N.K. & B.J. WHITTLE. 1983. Stimulation and inhibition of prostacyclin formation in the gastric mucosa and ileum in vitro by anti-inflammatory agents. Br. J. Pharmacol. 78: 173-180.
    • (1983) Br. J. Pharmacol. , vol.78 , pp. 173-180
    • Boughton-Smith, N.K.1    Whittle, B.J.2
  • 89
    • 0022297664 scopus 로고
    • Modulation of human colonic arachidonic acid metabolism by sulfasalazine
    • HAWKEY, C.J., N.K. BOUGHTON-SMITH & B.J. WHITTLE. 1985. Modulation of human colonic arachidonic acid metabolism by sulfasalazine. Dig. Dis. Sci. 30: 1161-1165.
    • (1985) Dig. Dis. Sci. , vol.30 , pp. 1161-1165
    • Hawkey, C.J.1    Boughton-Smith, N.K.2    Whittle, B.J.3
  • 90
    • 0022340674 scopus 로고
    • Prostaglandins and the gastrointestinal mucosa: Are they important in its function, disease, or treatment?
    • HAWKEY, C.J. & D.S. RAMPTON. 1985. Prostaglandins and the gastrointestinal mucosa: are they important in its function, disease, or treatment? Gastroenterology 89: 1162-1188.
    • (1985) Gastroenterology , vol.89 , pp. 1162-1188
    • Hawkey, C.J.1    Rampton, D.S.2
  • 91
    • 0027866677 scopus 로고
    • Gastroduodenal problems associated with non-steroidal, anti-inflammatory drugs (NSAIDs)
    • HAWKEY, C.J. 1993. Gastroduodenal problems associated with non-steroidal, anti-inflammatory drugs (NSAIDs). Scand. J. Gastroenterol. 200(Suppl): 94-95.
    • (1993) Scand. J. Gastroenterol. , vol.200 , Issue.SUPPL. , pp. 94-95
    • Hawkey, C.J.1
  • 92
    • 0023730122 scopus 로고
    • Use of colonic eicosanoid concentrations as predictors of relapse in ulcerative colitis: Double blind placebo controlled study on sulphasalazine maintenance treatment
    • LAURITSEN, K. et al. 1988. Use of colonic eicosanoid concentrations as predictors of relapse in ulcerative colitis: double blind placebo controlled study on sulphasalazine maintenance treatment. Gut 29: 1316-1321.
    • (1988) Gut , vol.29 , pp. 1316-1321
    • Lauritsen, K.1
  • 94
    • 0023759738 scopus 로고
    • Longterm olsalazine treatment: Pharmacokinetics, tolerance and effects on local eicosanoid formation in ulcerative colitis and Crohn's colitis
    • LAURITSEN, K. et al. 1988. Longterm olsalazine treatment: pharmacokinetics, tolerance and effects on local eicosanoid formation in ulcerative colitis and Crohn's colitis. Gut 29: 974-982.
    • (1988) Gut , vol.29 , pp. 974-982
    • Lauritsen, K.1
  • 95
    • 0023948516 scopus 로고
    • In vivo profiles of eicosanoids in ulcerative colitis, Crohn's colitis, and Clostridium difficile colitis
    • LAURITSEN, K. et al. 1988. In vivo profiles of eicosanoids in ulcerative colitis, Crohn's colitis, and Clostridium difficile colitis. Gastroenterology 95: 11-17.
    • (1988) Gastroenterology , vol.95 , pp. 11-17
    • Lauritsen, K.1
  • 96
    • 0018088258 scopus 로고
    • Chemotactic activity of thromboxane B2, prostaglandins and their metabolites for polymorphonuclear leucocytes
    • KITCHEN, E.A., J.R. BOOT & W. DAWSON. 1978. Chemotactic activity of thromboxane B2, prostaglandins and their metabolites for polymorphonuclear leucocytes. Prostaglandins 16: 239-244.
    • (1978) Prostaglandins , vol.16 , pp. 239-244
    • Kitchen, E.A.1    Boot, J.R.2    Dawson, W.3
  • 97
    • 0025921808 scopus 로고
    • Thromboxane A2 induces leukotriene B4 synthesis that in turn mediates neutrophil diapedesis via CD 18 activation
    • GOLDMAN, G. et al. 1991. Thromboxane A2 induces leukotriene B4 synthesis that in turn mediates neutrophil diapedesis via CD 18 activation. Microvasc. Res. 41: 367-375.
    • (1991) Microvasc. Res. , vol.41 , pp. 367-375
    • Goldman, G.1
  • 98
    • 0025811231 scopus 로고
    • Thromboxane-induced neutrophil adhesion to pulmonary microvascular and aortic endothelium is regulated by CD 18
    • WILES, M.E. et al. 1991. Thromboxane-induced neutrophil adhesion to pulmonary microvascular and aortic endothelium is regulated by CD 18. Inflammation 15: 181-199.
    • (1991) Inflammation , vol.15 , pp. 181-199
    • Wiles, M.E.1
  • 99
    • 0023900030 scopus 로고
    • Endothelial-secreted arachidonic acid metabolites modulate polymorphonuclear leukocyte chemotaxis and diapedesis in vitro
    • DOUKAS, J., H.B. HECHTMAN & D. SHEPRO. 1988. Endothelial-secreted arachidonic acid metabolites modulate polymorphonuclear leukocyte chemotaxis and diapedesis in vitro. Blood 71: 771-779.
    • (1988) Blood , vol.71 , pp. 771-779
    • Doukas, J.1    Hechtman, H.B.2    Shepro, D.3
  • 100
    • 0027331413 scopus 로고
    • Thromboxane A2 receptor is highly expressed in mouse immature thymocytes and mediates DNA fragmentation and apoptosis
    • USHIKUBI, F. et al. 1993. Thromboxane A2 receptor is highly expressed in mouse immature thymocytes and mediates DNA fragmentation and apoptosis. J. Exp. Med. 178: 1825-1830.
    • (1993) J. Exp. Med. , vol.178 , pp. 1825-1830
    • Ushikubi, F.1
  • 101
    • 0018416641 scopus 로고
    • Effect of inhibitors of arachidonic acid metabolism on mitogenesis in human lymphocytes: Possible role of thromboxanes and products of the lipoxygenase pathway
    • KELLY, J.P., M.C. JOHNSON & C.W. PARKER. 1979. Effect of inhibitors of arachidonic acid metabolism on mitogenesis in human lymphocytes: possible role of thromboxanes and products of the lipoxygenase pathway. J. Immunol. 122: 1563-1571.
    • (1979) J. Immunol. , vol.122 , pp. 1563-1571
    • Kelly, J.P.1    Johnson, M.C.2    Parker, C.W.3
  • 102
    • 0022134815 scopus 로고
    • Hypersensitive prostaglandin and thromboxane response to hormones in rabbit colitis
    • ZIPSER, R.D. et al. 1985. Hypersensitive prostaglandin and thromboxane response to hormones in rabbit colitis. Am. J. Physiol. 249(4 Pt 1): G457-G463.
    • (1985) Am. J. Physiol. , vol.249 , Issue.4 PART 1
    • Zipser, R.D.1
  • 103
    • 0026675356 scopus 로고
    • Mucosal capillary thrombi in rectal biopsies
    • DHILLON, A.P. et al. 1992. Mucosal capillary thrombi in rectal biopsies. Histopathology 21: 127-133.
    • (1992) Histopathology , vol.21 , pp. 127-133
    • Dhillon, A.P.1
  • 104
    • 0035054310 scopus 로고    scopus 로고
    • Ridogrel enemas in distal ulcerative colitis
    • AUWERDA, J.J. et al. 2001. Ridogrel enemas in distal ulcerative colitis. Eur. J. Gastroenterol. Hepatol. 13: 397-400.
    • (2001) Eur. J. Gastroenterol. Hepatol. , vol.13 , pp. 397-400
    • Auwerda, J.J.1
  • 105
    • 0036161782 scopus 로고    scopus 로고
    • Efficacy and safety of oral ridogrel in the treatment of ulcerative colitis: Two multicentre, randomized, double-blind studies
    • TYTGAT, G.N. et al. 2002. Efficacy and safety of oral ridogrel in the treatment of ulcerative colitis: two multicentre, randomized, double-blind studies. Aliment. Pharmacol. Ther. 16: 87-99.
    • (2002) Aliment. Pharmacol. Ther. , vol.16 , pp. 87-99
    • Tytgat, G.N.1
  • 106
    • 0030952289 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis
    • RISAU, W. 1997. Mechanisms of angiogenesis. Nature 386: 671-674.
    • (1997) Nature , vol.386 , pp. 671-674
    • Risau, W.1
  • 107
    • 0021978223 scopus 로고
    • Tumor angiogenesis
    • FOLKMAN, J. 1985. Tumor angiogenesis. Adv. Cancer Res. 43: 175-203.
    • (1985) Adv. Cancer Res. , vol.43 , pp. 175-203
    • Folkman, J.1
  • 108
    • 0032703283 scopus 로고    scopus 로고
    • Angiogenesis and arthritis
    • WALSH, D.A. 1999. Angiogenesis and arthritis. Rheumatology (Oxford) 38: 103-112.
    • (1999) Rheumatology (Oxford) , vol.38 , pp. 103-112
    • Walsh, D.A.1
  • 109
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • FOLKMAN, J. 1995. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. 1: 27-31.
    • (1995) Nat. Med. , vol.1 , pp. 27-31
    • Folkman, J.1
  • 110
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • HANAHAN, D. & J. FOLKMAN. 1996. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86: 353-364.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 111
    • 0030639289 scopus 로고    scopus 로고
    • Role of the macrophage in angiogenesis-dependent diseases
    • POLVERINI, P.J. 1997. Role of the macrophage in angiogenesis-dependent diseases. EXS 79: 11-28.
    • (1997) EXS , vol.79 , pp. 11-28
    • Polverini, P.J.1
  • 112
    • 0033597718 scopus 로고    scopus 로고
    • Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis
    • CARMELIET, P. et al. 1999. Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis. Cell 98: 147-157.
    • (1999) Cell , vol.98 , pp. 147-157
    • Carmeliet, P.1
  • 113
    • 0032925156 scopus 로고    scopus 로고
    • Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188
    • CARMELIET, P. et al. 1999. Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Nat. Med. 5: 495-502.
    • (1999) Nat. Med. , vol.5 , pp. 495-502
    • Carmeliet, P.1
  • 114
    • 0032889971 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor and vascular endothelial growth factor receptors in vascular development
    • CARMELIET, P. & D. COLLEN. 1999. Role of vascular endothelial growth factor and vascular endothelial growth factor receptors in vascular development. Curr. Top. Microbiol. Immunol. 237: 133-158.
    • (1999) Curr. Top. Microbiol. Immunol. , vol.237 , pp. 133-158
    • Carmeliet, P.1    Collen, D.2
  • 115
    • 0032710319 scopus 로고    scopus 로고
    • Clinical applications of angiogenic growth factors and their inhibitors
    • FERRARA, N. & K. ALITALO. 1999. Clinical applications of angiogenic growth factors and their inhibitors. Nat. Med. 5: 1359-1364.
    • (1999) Nat. Med. , vol.5 , pp. 1359-1364
    • Ferrara, N.1    Alitalo, K.2
  • 116
    • 0029117902 scopus 로고
    • Expression of basic fibroblast growth factor in synovial tissue from patients with rheumatoid arthritis and degenerative joint disease
    • Qu, Z. et al. 1995. Expression of basic fibroblast growth factor in synovial tissue from patients with rheumatoid arthritis and degenerative joint disease. Lab. Invest. 73: 339-346.
    • (1995) Lab. Invest. , vol.73 , pp. 339-346
    • Qu, Z.1
  • 117
    • 0029117071 scopus 로고
    • Mast cells are a major source of basic fibroblast growth factor in chronic inflammation and cutaneous hemangioma
    • Qu, Z. et al. 1995. Mast cells are a major source of basic fibroblast growth factor in chronic inflammation and cutaneous hemangioma. Am. J. Pathol. 147: 564-573.
    • (1995) Am. J. Pathol. , vol.147 , pp. 564-573
    • Qu, Z.1
  • 118
    • 0031913045 scopus 로고    scopus 로고
    • Focally regulated endothelial proliferation and cell death in human synovium
    • WALSH, D.A. et al. 1998. Focally regulated endothelial proliferation and cell death in human synovium. Am. J. Pathol. 152: 691-702.
    • (1998) Am. J. Pathol. , vol.152 , pp. 691-702
    • Walsh, D.A.1
  • 119
    • 0031665137 scopus 로고    scopus 로고
    • Joint physiology and synovial cell proliferation
    • WALSH, D.A. & P.I. MAPP. 1998. Joint physiology and synovial cell proliferation. Br. J. Rheumatol. 37: 1032-1033.
    • (1998) Br. J. Rheumatol. , vol.37 , pp. 1032-1033
    • Walsh, D.A.1    Mapp, P.I.2
  • 120
    • 0032408615 scopus 로고    scopus 로고
    • Vascular turnover during carrageenan synovitis in the rat
    • WALSH, D.A., H.A. RODWAY & A. CLAXSON. 1998. Vascular turnover during carrageenan synovitis in the rat. Lab. Invest. 78: 1513-1521.
    • (1998) Lab. Invest. , vol.78 , pp. 1513-1521
    • Walsh, D.A.1    Rodway, H.A.2    Claxson, A.3
  • 121
    • 27444447371 scopus 로고    scopus 로고
    • Histidine-richglycoprotein specifically binds to necrotic cells via its amino-terminal domain and facilitates necrotic cell phagocytosis
    • JONES, A.L. et al. 2005. Histidine-richglycoprotein specifically binds to necrotic cells via its amino-terminal domain and facilitates necrotic cell phagocytosis. J. Biol. Chem. 280: 35733-35741.
    • (2005) J. Biol. Chem. , vol.280 , pp. 35733-35741
    • Jones, A.L.1
  • 122
    • 1942439974 scopus 로고    scopus 로고
    • Fibrinogen catabolism within the procoagulant VX-2 tumor of rabbit lung in vivo: Effluxing fibrin(ogen) fragments contain antiangiogenic activity
    • HATTON, M.W. et al. 2004. Fibrinogen catabolism within the procoagulant VX-2 tumor of rabbit lung in vivo: effluxing fibrin(ogen) fragments contain antiangiogenic activity. J. Lab. Clin. Med. 143: 241-254.
    • (2004) J. Lab. Clin. Med. , vol.143 , pp. 241-254
    • Hatton, M.W.1
  • 123
    • 0142112011 scopus 로고    scopus 로고
    • Hemostatic regulators of tumor angiogenesis: A source of antiangiogenic agents for cancer treatment?
    • DALY, M.E. et al. 2003. Hemostatic regulators of tumor angiogenesis: a source of antiangiogenic agents for cancer treatment? J. Natl. Cancer Inst. 95: 1660-1073.
    • (2003) J. Natl. Cancer Inst. , vol.95 , pp. 1660-11073
    • Daly, M.E.1
  • 124
    • 0036604429 scopus 로고    scopus 로고
    • Generation of biologically active angiostatin kringle 1-3 by activated human neutrophils
    • SCAPINI, P. et al. 2002. Generation of biologically active angiostatin kringle 1-3 by activated human neutrophils. J. Immunol. 168: 5798-5804.
    • (2002) J. Immunol. , vol.168 , pp. 5798-5804
    • Scapini, P.1
  • 125
    • 0036786256 scopus 로고    scopus 로고
    • Basic fibroblast growth factor stimulates osteoclast recruitment, development, and bone pit resorption in association with angiogenesis in vivo on the chick chorioallantoic membrane and activates isolated avian osteoclast resorption in vitro
    • COLLIN-OSDOBY, P. et al. 2002. Basic fibroblast growth factor stimulates osteoclast recruitment, development, and bone pit resorption in association with angiogenesis in vivo on the chick chorioallantoic membrane and activates isolated avian osteoclast resorption in vitro. J. Bone Miner. Res. 17: 1859-1871.
    • (2002) J. Bone Miner. Res. , vol.17 , pp. 1859-1871
    • Collin-Osdoby, P.1
  • 126
    • 12144271043 scopus 로고    scopus 로고
    • Mechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cells
    • OGAWA, H. et al. 2005. Mechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cells. Am. J. Physiol. Cell. Physiol. 288: C272-C281.
    • (2005) Am. J. Physiol. Cell. Physiol. , vol.288
    • Ogawa, H.1
  • 127
    • 0036928539 scopus 로고    scopus 로고
    • Inflammation and free radicals in tumor development and progression
    • OKADA, F. 2002. Inflammation and free radicals in tumor development and progression. Redox. Rep. 7: 357-368.
    • (2002) Redox. Rep. , vol.7 , pp. 357-368
    • Okada, F.1
  • 128
    • 17844404308 scopus 로고    scopus 로고
    • Involvement of mast cells in angiogenesis and chronic inflammation
    • CRIVELLATO, E. & D. RIBATTI. 2005. Involvement of mast cells in angiogenesis and chronic inflammation. Curr. Drug Targets Inflamm. Allergy 4: 9-11.
    • (2005) Curr. Drug Targets Inflamm. Allergy , vol.4 , pp. 9-11
    • Crivellato, E.1    Ribatti, D.2
  • 129
    • 0035433215 scopus 로고    scopus 로고
    • Association between shear stress, angiogenesis, and VEGF in skeletal muscles in vivo
    • MILKIEWICZ, M. et al. 2001. Association between shear stress, angiogenesis, and VEGF in skeletal muscles in vivo. Microcirculation 8: 229-241.
    • (2001) Microcirculation , vol.8 , pp. 229-241
    • Milkiewicz, M.1
  • 130
    • 0036791647 scopus 로고    scopus 로고
    • Pulsatile flow-induced angiogenesis: Role of G(i) subunits
    • CULLEN, J.P. et al. 2002. Pulsatile flow-induced angiogenesis: role of G(i) subunits. Arterioscler. Thromb. Vasc. Biol. 22: 1610-1616.
    • (2002) Arterioscler. Thromb. Vasc. Biol. , vol.22 , pp. 1610-1616
    • Cullen, J.P.1
  • 133
    • 0038071763 scopus 로고    scopus 로고
    • Expression of platelet-derived endothelial cell growth factor in inflammatory bowel disease
    • SAITO, S. et al. 2003. Expression of platelet-derived endothelial cell growth factor in inflammatory bowel disease. J. Gastroenterol. 38: 229-237.
    • (2003) J. Gastroenterol. , vol.38 , pp. 229-237
    • Saito, S.1
  • 134
    • 0035072493 scopus 로고    scopus 로고
    • VEGF, basic-FGF, and TGF-beta in Crohn's disease and ulcerative colitis: A novel mechanism of chronic intestinal inflammation
    • KANAZAWA, S. et al. 2001. VEGF, basic-FGF, and TGF-beta in Crohn's disease and ulcerative colitis: a novel mechanism of chronic intestinal inflammation. Am. J. Gastroenterol. 96: 822-828.
    • (2001) Am. J. Gastroenterol. , vol.96 , pp. 822-828
    • Kanazawa, S.1
  • 135
    • 4944228048 scopus 로고    scopus 로고
    • Activity of Crohn disease: Value of Color-Power-Doppler and contrast-enhanced ultrasonography
    • ROBOTTI, D. et al. 2004. Activity of Crohn disease: value of Color-Power-Doppler and contrast-enhanced ultrasonography. Abdom. Imaging 29: 648-652.
    • (2004) Abdom. Imaging , vol.29 , pp. 648-652
    • Robotti, D.1
  • 136
    • 4043146471 scopus 로고    scopus 로고
    • Doppler sonography in the diagnosis of inflammatory bowel disease
    • DI SABATINO, A., E. ARMELLINI & G.R. CORAZZA. 2004. Doppler sonography in the diagnosis of inflammatory bowel disease. Dig. Dis. 22: 63-66.
    • (2004) Dig. Dis. , vol.22 , pp. 63-66
    • Di Sabatino, A.1    Armellini, E.2    Corazza, G.R.3
  • 137
    • 26044463899 scopus 로고    scopus 로고
    • Starving the inflamed gut: Angiogenesis blocked as a novel therapeutic approach to experimental colitis
    • DANESE, S.S.M., D. SPENCER, I. BECK, et al. 2005. Starving the inflamed gut: angiogenesis blocked as a novel therapeutic approach to experimental colitis. Gastroenterology 128: A-40.
    • (2005) Gastroenterology , vol.128
    • Danese, S.S.M.1    Spencer, D.2    Beck, I.3
  • 139
    • 0030847525 scopus 로고    scopus 로고
    • Modulation of angiogenesis in a model of chronic inflammation
    • JACKSON, J.R. et al. 1997. Modulation of angiogenesis in a model of chronic inflammation. Inflamm. Res. 46(Suppl 2:) S129-S130.
    • (1997) Inflamm. Res. , vol.46 , Issue.SUPPL. 2
    • Jackson, J.R.1
  • 140
    • 0024419176 scopus 로고
    • Inhibition of in vitro vascular endothelial cell proliferation and in vivo neovascularization by low-dose methotrexate
    • HIRATA, S. et al. 1989. Inhibition of in vitro vascular endothelial cell proliferation and in vivo neovascularization by low-dose methotrexate. Arthritis Rheum. 32: 1065-1073.
    • (1989) Arthritis Rheum. , vol.32 , pp. 1065-1073
    • Hirata, S.1
  • 141
    • 17844393860 scopus 로고    scopus 로고
    • Antiangiogenesis for rheumatoid arthritis
    • ROCCARO, A.M. et al. 2005. Antiangiogenesis for rheumatoid arthritis. Curr. Drug Targets Inflamm. Allergy 4: 27-30.
    • (2005) Curr. Drug Targets Inflamm. Allergy , vol.4 , pp. 27-30
    • Roccaro, A.M.1
  • 142
    • 0036257310 scopus 로고    scopus 로고
    • Treatment with the angiogenesis inhibitor endostatin: A novel therapy in rheumatoid arthritis
    • MATSUNO, H. et al. 2002. Treatment with the angiogenesis inhibitor endostatin: a novel therapy in rheumatoid arthritis. J. Rheumatol. 29: 890-895.
    • (2002) J. Rheumatol. , vol.29 , pp. 890-895
    • Matsuno, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.