Erratum: Chemical and genetic evidence for the involvement of Wnt antagonist Dickkopf2 in regulation of glucose metabolism (Proceedings of the National Academy of Sciences of the United States of America (2012) 109, 28 (11402-11407) DOI: 10.1073/pnas.1205015109);Chemical and genetic evidence for the involvement of Wnt antagonist Dickkopf2 in regulation of glucose metabolism

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 28, 2012, Pages 11402-11407

  Li, Xiaofeng ^a,b   Shan, Jufang ^c   Chang, Woochul ^a   Kim, Ingyu ^a   Bao, Ju ^c   Lee, Ho Jin ^c   Zhang, Xinxin ^c   Samuel, Varman T ^a,d   Shulman, Gerald I ^a   Liu, Dakai ^b   Zheng, Jie J ^c   Wu, Dianqing ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Enzo Therapeutics   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

Signal transduction

Indexed keywords

DICKKOPF2; GLUCOSE; GLYCOGEN; GLYCOPROTEIN; INSULIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; GLUCOSE METABOLISM; INTESTINE; LIVER; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL;

MUS;

EID: 84863935919     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1215480109     Document Type: Erratum

References (45)

1. Logan CY, Nusse R (2004) The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 20:781-810. (Pubitemid 39488658)
2. Clevers H (2006) Wnt/beta-catenin signaling in development and disease. Cell 127:469-480.
3. Moon RT, Kohn AD, De Ferrari GV, Kaykas A (2004) WNT and beta-catenin signalling: Diseases and therapies. Nat Rev Genet 5:691-701. (Pubitemid 39150127)
4. MacDonald BT, Tamai K, He X (2009) Wnt/beta-catenin signaling: Components, mechanisms, and diseases. Dev Cell 17:9-26.
5. Monaghan AP, et al. (1999) Dickkopf genes are co-ordinately expressed in mesodermal lineages. Mech Dev 87:45-56. (Pubitemid 29428085)
6. Krupnik VE, et al. (1999) Functional and structural diversity of the human Dickkopf gene family. Gene 238:301-313. (Pubitemid 29447031)
7. Mao B, et al. (2001) LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature 411:321-325. (Pubitemid 32467039)
8. Semënov MV, et al. (2001) Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. Curr Biol 11:951-961.
9. Bafico A, Liu G, Yaniv A, Gazit A, Aaronson SA (2001) Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow. Nat Cell Biol 3:683-686. (Pubitemid 32624426)
10. Niehrs C (2006) Function and biological roles of the Dickkopf family of Wnt modulators. Oncogene 25:7469-7481.
11. Li L, Mao J, Sun L, Liu W, Wu D (2002) Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled. J Biol Chem 277:5977-5981. (Pubitemid 34968379)
12. Brott BK, Sokol SY (2002) Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins. Mol Cell Biol 22:6100-6110. (Pubitemid 34857830)
13. Chen L, et al. (2008) Structural insight into the mechanisms of Wnt signaling antagonism by Dkk. J Biol Chem 283:23364-23370.
14. Wang K, et al. (2008) Characterization of the Kremen-binding site on Dkk1 and elucidation of the role of Kremen in Dkk-mediated Wnt antagonism. J Biol Chem 283:23371-23375.
15. Zhang Y, et al. (2004) The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with Mesd. Mol Cell Biol 24:4677-4684. (Pubitemid 38668035)
16. Smith TF, Gaitatzes C, Saxena K, Neer EJ (1999) The WD repeat: A common architecture for diverse functions. Trends Biochem Sci 24:181-185. (Pubitemid 29348450)
17. Jeon H, et al. (2001) Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair. Nat Struct Biol 8:499-504. (Pubitemid 32525007)
18. Sondek J, Bohm A, Lambright DG, Hamm HE, Sigler PB (1996) Crystal structure of a G-protein beta gamma dimer at 2.1A resolution. Nature 379:369-374.
19. Takagi J, Yang Y, Liu JH, Wang JH, Springer TA (2003) Complex between nidogen and laminin fragments reveals a paradigmatic beta-propeller interface. Nature 424:969-974. (Pubitemid 37051691)
20. Cheng Z, et al. (2011) Crystal structures of the extracellular domain of LRP6 and its complex with DKK1. Nat Struct Mol Biol 18:1204-1210.
21. Chen S, et al. (2011) Structural and functional studies of LRP6 ectodomain reveal a platform for Wnt signaling. Dev Cell 21:848-861.
22. Ahn VE, et al. (2011) Structural basis of Wnt signaling inhibition by Dickkopf binding to LRP5/6. Dev Cell 21:862-873.
23. Jin T (2008) The WNT signalling pathway and diabetes mellitus. Diabetologia 51:1771-1780.
24. Grant SF, et al. (2006) Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 38:320-323.
25. Scott LJ, et al. (2007) A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 316:1341-1345. (Pubitemid 46871655)
26. Yi F, Brubaker PL, Jin T (2005) TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta. J Biol Chem 280:1457-1464.
27. Mani A, et al. (2007) LRP6 mutation in a family with early coronary disease and metabolic risk factors. Science 315:1278-1282. (Pubitemid 46364265)
28. Fujino T, et al. (2003) Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion. Proc Natl Acad Sci USA 100:229-234. (Pubitemid 36078057)
29. Rulifson IC, et al. (2007) Wnt signaling regulates pancreatic beta cell proliferation. Proc Natl Acad Sci USA 104:6247-6252. (Pubitemid 47186080)
30. Hurst T (1994) Flexible 3D searching - The directed tweak technique. J Chem Inf Comput Sci 34:190-196.
31. Hoffmann D, et al. (1999) Two-stage method for protein-ligand docking. J Med Chem 42:4422-4433. (Pubitemid 29504146)
32. Kramer B, Rarey M, Lengauer T (1999) Evaluation of the FLEXX incremental construction algorithm for protein-ligand docking. Proteins 37:228-241. (Pubitemid 29503004)
33. Li X, et al. (2005) Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation. Nat Genet 37:945-952. (Pubitemid 43086150)
34. Williams BO, Insogna KL (2009) Where Wnts went: The exploding field of Lrp5 and Lrp6 signaling in bone. J Bone Miner Res 24:171-178.
35. MacDonald BT, et al. (2007) Bone mass is inversely proportional to Dkk1 levels in mice. Bone 41:331-339. (Pubitemid 47199155)
36. Glantschnig H, et al. (2010) Generation and selection of novel fully human monoclonal antibodies that neutralize Dickkopf-1 (DKK1) inhibitory function in vitro and increase bone mass in vivo. J Biol Chem 285:40135-40147.
37. Li J, et al. (2006) Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia. Bone 39:754-766. (Pubitemid 44311706)
38. Abu-Hamdah R, et al. (2009) Clinical review: The extrapancreatic effects of glucagon-like peptide-1 and related peptides. J Clin Endocrinol Metab 94:1843-1852.
39. Ramnanan CJ, Edgerton DS, Kraft G, Cherrington AD (2011) Physiologic action of glucagon on liver glucose metabolism. Diabetes Obes Metab 13(Suppl 1):118-125.
40. Miller RA, Birnbaum MJ (2010) An energetic tale of AMPK-independent effects of metformin. J Clin Invest 120:2267-2270.
41. Printen JA, Brady MJ, Saltiel AR (1997) PTG, a protein phosphatase 1-binding protein with a role in glycogen metabolism. Science 275:1475-1478. (Pubitemid 27111295)
42. Zeve D, et al. (2012) Wnt signaling activation in adipose progenitors promotes insulin-independent muscle glucose uptake. Cell Metab 15:492-504.
43. Morvan F, et al. (2006) Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass. J Bone Miner Res 21:934-945. (Pubitemid 43788000)
44. Shoichet BK (2004) Virtual screening of chemical libraries. Nature 432:862-865.
45. Bonacci TM, et al. (2006) Differential targeting of Gbetagamma-subunit signaling with small molecules. Science 312:443-446.