-
1
-
-
17544367410
-
Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
-
Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 1996;271:12687-12690.
-
(1996)
J Biol Chem
, vol.271
, pp. 12687-12690
-
-
Pitti, R.M.1
Marsters, S.A.2
Ruppert, S.3
Donahue, C.J.4
Moore, A.5
Ashkenazi, A.6
-
2
-
-
13344285339
-
Identifi cation and characterization of a new member of the TNF family that induces apoptosis
-
Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK, et al. Identifi cation and characterization of a new member of the TNF family that induces apoptosis. Immunity 1995;3: 673-682.
-
(1995)
Immunity
, vol.3
, pp. 673-682
-
-
Wiley, S.R.1
Schooley, K.2
Smolak, P.J.3
Din, W.S.4
Huang, C.P.5
Nicholl, J.K.6
-
3
-
-
0032929520
-
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
-
Walczak H, Miller RE, Ariail K, Gliniak B, Griffi th TS, Kubin M, et al. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 1999;5:157-163.
-
(1999)
Nat Med
, vol.5
, pp. 157-163
-
-
Walczak, H.1
Miller, R.E.2
Ariail, K.3
Gliniak, B.4
Griffith, T.S.5
Kubin, M.6
-
4
-
-
0032713075
-
Safety and antitumor activity of recombinant soluble Apo2 ligand
-
Ashkenazi A, Pai RC, Fong S, Leung S, Lawrence DA, Marsters SA, et al. Safety and antitumor activity of recombinant soluble Apo2 ligand. J Clin Invest 1999;104:155-162.
-
(1999)
J Clin Invest
, vol.104
, pp. 155-162
-
-
Ashkenazi, A.1
Pai, R.C.2
Fong, S.3
Leung, S.4
Lawrence, D.A.5
Marsters, S.A.6
-
5
-
-
34547819299
-
The promise of TRAIL-potential and risks of a novel anticancer therapy
-
Koschny R, Walczak H, Ganten TM. The promise of TRAIL-potential and risks of a novel anticancer therapy. J Mol Med 2007;85:923-935.
-
(2007)
J Mol Med
, vol.85
, pp. 923-935
-
-
Koschny, R.1
Walczak, H.2
Ganten, T.M.3
-
6
-
-
0037273848
-
Apo2L/TRAIL and its death and decoy receptors
-
LeBlanc HN, Ashkenazi A. Apo2L/TRAIL and its death and decoy receptors. Cell Death Differ 2003;10:66-75.
-
(2003)
Cell Death Differ
, vol.10
, pp. 66-75
-
-
Leblanc, H.N.1
Ashkenazi, A.2
-
7
-
-
0242467470
-
Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis
-
Joy AM, Beaudry CE, Tran NL, Ponce FA, Holz DR, Demuth T, Berens ME. Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis. J Cell Sci 2003;116(Pt 21):4409-4417.
-
(2003)
J Cell Sci
, vol.116
, Issue.PART 21
, pp. 4409-4417
-
-
Joy, A.M.1
Beaudry, C.E.2
Tran, N.L.3
Ponce, F.A.4
Holz, D.R.5
Demuth, T.6
Berens, M.E.7
-
8
-
-
0030996297
-
The receptor for the cytotoxic ligand TRAIL
-
Pan G, O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J, Dixit VM. The receptor for the cytotoxic ligand TRAIL. Science 1997;276:111-113.
-
(1997)
Science
, vol.276
, pp. 111-113
-
-
Pan, G.1
O'Rourke, K.2
Chinnaiyan, A.M.3
Gentz, R.4
Ebner, R.5
Ni, J.6
Dixit, V.M.7
-
9
-
-
0030762815
-
An antagonist decoy receptor and a death domain-containing receptor for TRAIL
-
Pan G, Ni J, Wei YF, Yu G, Gentz R, Dixit VM. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science 1997;277:815-818.
-
(1997)
Science
, vol.277
, pp. 815-818
-
-
Pan, G.1
Ni, J.2
Wei, Y.F.3
Yu, G.4
Gentz, R.5
Dixit, V.M.6
-
10
-
-
0030792712
-
Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
-
Sheridan JP, Marsters SA, Pitti RM, Gurney A, Skubatch M, Baldwin D, et al. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science 1997;277: 818-821.
-
(1997)
Science
, vol.277
, pp. 818-821
-
-
Sheridan, J.P.1
Marsters, S.A.2
Pitti, R.M.3
Gurney, A.4
Skubatch, M.5
Baldwin, D.6
-
11
-
-
13144265771
-
A novel receptor for Apo2L/TRAIL contains a truncated death domain
-
Marsters SA, Sheridan JP, Pitti RM, Huang A, Skubatch M, Baldwin D, et al. A novel receptor for Apo2L/TRAIL contains a truncated death domain. Curr Biol 1997;7:1003-1006.
-
(1997)
Curr Biol
, vol.7
, pp. 1003-1006
-
-
Marsters, S.A.1
Sheridan, J.P.2
Pitti, R.M.3
Huang, A.4
Skubatch, M.5
Baldwin, D.6
-
12
-
-
7344233085
-
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL
-
Emery JG, McDonnell P, Burke MB, Deen KC, Lyn S, Silverman C, et al. Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J Biol Chem 1998;273:14363-14367.
-
(1998)
J Biol Chem
, vol.273
, pp. 14363-14367
-
-
Emery, J.G.1
McDonnell, P.2
Burke, M.B.3
Deen, K.C.4
Lyn, S.5
Silverman, C.6
-
13
-
-
0030925774
-
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
-
Medema JP, Scaffi di C, Kischkel FC, Shevchenko A, Mann M, Krammer PH, Peter ME. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J 1997;16:2794-2804.
-
(1997)
EMBO J
, vol.16
, pp. 2794-2804
-
-
Medema, J.P.1
Scaffi Di, C.2
Kischkel, F.C.3
Shevchenko, A.4
Mann, M.5
Krammer, P.H.6
Peter, M.E.7
-
14
-
-
0028883850
-
Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
-
Kischkel FC, Hellbardt S, Behrmann I, Germer M, Pawlita M, Krammer PH, Peter ME. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J 1995;14:5579-5588.
-
(1995)
EMBO J
, vol.14
, pp. 5579-5588
-
-
Kischkel, F.C.1
Hellbardt, S.2
Behrmann, I.3
Germer, M.4
Pawlita, M.5
Krammer, P.H.6
Peter, M.E.7
-
15
-
-
0033662433
-
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
-
Kischkel FC, Lawrence DA, Chuntharapai A, Schow P, Kim KJ, Ashkenazi A. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity 2000;12:611-620.
-
(2000)
Immunity
, vol.12
, pp. 611-620
-
-
Kischkel, F.C.1
Lawrence, D.A.2
Chuntharapai, A.3
Schow, P.4
Kim, K.J.5
Ashkenazi, A.6
-
16
-
-
0842281645
-
Cell death: Critical control points
-
Danial NN, Korsmeyer SJ. Cell death: critical control points. Cell 2004;116:205-219.
-
(2004)
Cell
, vol.116
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
17
-
-
25144489068
-
Overview of cell death signaling pathways
-
Jin Z, El-Deiry WS. Overview of cell death signaling pathways. Cancer Biol Ther 2005;4:139-163.
-
(2005)
Cancer Biol Ther
, vol.4
, pp. 139-163
-
-
Jin, Z.1
El-Deiry, W.S.2
-
18
-
-
34250753161
-
Cell death modalities: Classifi cation and pathophysiological implications
-
Galluzzi L, Maiuri MC, Vitale I, Zischka H, Castedo M, Zitvogel L, Kroemer G. Cell death modalities: classifi cation and pathophysiological implications. Cell Death Differ 2007;14:1237-1243.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1237-1243
-
-
Galluzzi, L.1
Maiuri, M.C.2
Vitale, I.3
Zischka, H.4
Castedo, M.5
Zitvogel, L.6
Kroemer, G.7
-
19
-
-
0036479001
-
And all of a sudden it's over: Mitochondrial outer-membrane permeabilization in apoptosis
-
Waterhouse NJ, Ricci JE, Green DR. And all of a sudden it's over: mitochondrial outer-membrane permeabilization in apoptosis. Biochimie 2002;84:113-121.
-
(2002)
Biochimie
, vol.84
, pp. 113-121
-
-
Waterhouse, N.J.1
Ricci, J.E.2
Green, D.R.3
-
20
-
-
0030745646
-
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
-
Zou H, Henzel WJ, Liu X, Lutschg A, Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 1997;90:405-413.
-
(1997)
Cell
, vol.90
, pp. 405-413
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
-
21
-
-
0036859738
-
Defi ning characteristics of Types i and II apoptotic cells in response to TRAIL
-
Ozoren N, El-Deiry WS. Defi ning characteristics of Types I and II apoptotic cells in response to TRAIL. Neoplasia 2002;4: 551-557.
-
(2002)
Neoplasia
, vol.4
, pp. 551-557
-
-
Ozoren, N.1
El-Deiry, W.S.2
-
22
-
-
0033210894
-
Selectivity of TRAIL-mediated apoptosis of cancer cells and synergy with drugs: The trail to non-toxic cancer therapeutics (review)
-
Bonavida B, Ng CP, Jazirehi A, Schiller G, Mizutani Y. Selectivity of TRAIL-mediated apoptosis of cancer cells and synergy with drugs: the trail to non-toxic cancer therapeutics (review). Int J Oncol 1999;15:793-802.
-
(1999)
Int J Oncol
, vol.15
, pp. 793-802
-
-
Bonavida, B.1
Ng, C.P.2
Jazirehi, A.3
Schiller, G.4
Mizutani, Y.5
-
23
-
-
21344474349
-
Contribution of epigenetic silencing of tumor necrosis factorrelated apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer
-
Horak P, Pils D, Haller G, Pribill I, Roessler M, Tomek S, et al. Contribution of epigenetic silencing of tumor necrosis factorrelated apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer. Mol Cancer Res 2005;3:335-343.
-
(2005)
Mol Cancer Res
, vol.3
, pp. 335-343
-
-
Horak, P.1
Pils, D.2
Haller, G.3
Pribill, I.4
Roessler, M.5
Tomek, S.6
-
24
-
-
0037621450
-
Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation
-
Hopkins-Donaldson S, Ziegler A, Kurtz S, Bigosch C, Kandioler D, Ludwig C, et al. Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation. Cell Death Differ 2003;10:356-364.
-
(2003)
Cell Death Differ
, vol.10
, pp. 356-364
-
-
Hopkins-Donaldson, S.1
Ziegler, A.2
Kurtz, S.3
Bigosch, C.4
Kandioler, D.5
Ludwig, C.6
-
25
-
-
17744364468
-
Somatic mutations of TRAIL-receptor 1 and TRAIL-receptor 2 genes in non-Hodgkin's lymphoma
-
Lee SH, Shin MS, Kim HS, Lee HK, Park WS, Kim SY, et a l. Somatic mutations of TRAIL-receptor 1 and TRAIL-receptor 2 genes in non-Hodgkin's lymphoma. Oncogene 2001;20: 399-403.
-
(2001)
Oncogene
, vol.20
, pp. 399-403
-
-
Lee, S.H.1
Shin, M.S.2
Kim, H.S.3
Lee, H.K.4
Park, W.S.5
Kim, S.Y.6
-
26
-
-
0035394722
-
Mutations of tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1) and receptor 2 (TRAIL-R2) genes in metastatic breast cancers
-
Shin MS, Kim HS, Lee SH, Park WS, Kim SY, Park JY, et a l. Mutations of tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1) and receptor 2 (TRAIL-R2) genes in metastatic breast cancers. Cancer Res 2001;61: 4942-4946.
-
(2001)
Cancer Res
, vol.61
, pp. 4942-4946
-
-
Shin, M.S.1
Kim, H.S.2
Lee, S.H.3
Park, W.S.4
Kim, S.Y.5
Park, J.Y.6
-
27
-
-
4143115887
-
Defi cient tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis
-
Jin Z, McDonald ER, 3rd, Dicker DT, El-Deiry WS. Defi cient tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis. J Biol Chem 2004;279:35829-35839.
-
(2004)
J Biol Chem
, vol.279
, pp. 35829-35839
-
-
Jin, Z.1
McDonald Iii., E.R.2
Dicker, D.T.3
El-Deiry, W.S.4
-
28
-
-
33749164762
-
Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2
-
Merino D, Lalaoui N, Morizot A, Schneider P, Solary E, Micheau O. Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. Mol Cell Biol 2006;26:7046-7055.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7046-7055
-
-
Merino, D.1
Lalaoui, N.2
Morizot, A.3
Schneider, P.4
Solary, E.5
Micheau, O.6
-
29
-
-
0035920230
-
Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1
-
Bernard D, Quatannens B, Vandenbunder B, Abbadie C. Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1. J Biol Chem 2001;276:27322-27328.
-
(2001)
J Biol Chem
, vol.276
, pp. 27322-27328
-
-
Bernard, D.1
Quatannens, B.2
Vandenbunder, B.3
Abbadie, C.4
-
30
-
-
62449196599
-
LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors
-
Shenoy K, Wu Y, Pervaiz S. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors. Cancer Res 2009;69:1941-1950.
-
(2009)
Cancer Res
, vol.69
, pp. 1941-1950
-
-
Shenoy, K.1
Wu, Y.2
Pervaiz, S.3
-
31
-
-
33749568038
-
Curcumin sensitizes tumor necrosis factor-related apoptosisinducing ligand (TRAIL)-mediated apoptosis through CHOPindependent DR5 upregulation
-
Jung EM, Park JW, Choi KS, Lee HI, Lee KS, Kwon TK. Curcumin sensitizes tumor necrosis factor-related apoptosisinducing ligand (TRAIL)-mediated apoptosis through CHOPindependent DR5 upregulation. Carcinogenesis 2006;27: 2008-2017.
-
(2006)
Carcinogenesis
, vol.27
, pp. 2008-2017
-
-
Jung, E.M.1
Park, J.W.2
Choi, K.S.3
Lee, H.I.4
Lee, K.S.5
Kwon, T.K.6
-
32
-
-
32944475745
-
Sulforaphane sensitizes tumor necrosis factorrelated apoptosis-inducing ligand (TRAIL)-resistant hepatoma cells to TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of DR5
-
Kim H, Kim EH, Eom YW, Kim WH, Kwon TK, Lee SJ, Choi KS. Sulforaphane sensitizes tumor necrosis factorrelated apoptosis-inducing ligand (TRAIL)-resistant hepatoma cells to TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of DR5. Cancer Res 2006;66: 1740-1750.
-
(2006)
Cancer Res
, vol.66
, pp. 1740-1750
-
-
Kim, H.1
Kim, E.H.2
Eom, Y.W.3
Kim, W.H.4
Kwon, T.K.5
Lee, S.J.6
Choi, K.S.7
-
33
-
-
31544432335
-
Histone deacetylase inhibitors modulate the sensitivity of tumor necrosis factorrelated apoptosis-inducing ligand-resistant bladder tumor cells
-
Earel JK, Jr., VanOosten RL, Griffi th TS. Histone deacetylase inhibitors modulate the sensitivity of tumor necrosis factorrelated apoptosis-inducing ligand-resistant bladder tumor cells. Cancer Res 2006;66:499-507.
-
(2006)
Cancer Res
, vol.66
, pp. 499-507
-
-
Earel Jr., J.K.1
Vanoosten, R.L.2
Griffith, T.S.3
-
34
-
-
49849089793
-
Proteasome inhibitor PS-341 (VELCADE) induces stabilization of the TRAIL receptor DR5 mRNA through the 3 '-untranslated region
-
Kandasamy K, Kraft AS. Proteasome inhibitor PS-341 (VELCADE) induces stabilization of the TRAIL receptor DR5 mRNA through the 3 '-untranslated region. Mol Cancer Ther 2008;7:1091-1100.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1091-1100
-
-
Kandasamy, K.1
Kraft, A.S.2
-
35
-
-
21344453520
-
Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancer-binding protein homologous protein
-
Yoshida T, Shiraishi T, Nakata S, Horinaka M, Wakada M, Mizutani Y, et al. Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancer-binding protein homologous protein. Cancer Res 2005;65:5662-5667.
-
(2005)
Cancer Res
, vol.65
, pp. 5662-5667
-
-
Yoshida, T.1
Shiraishi, T.2
Nakata, S.3
Horinaka, M.4
Wakada, M.5
Mizutani, Y.6
-
36
-
-
67349228750
-
Withaferin A sensitizes TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP
-
Lee TJ, Um HJ, Min do S, Park JW, Choi KS, Kwon TK. Withaferin A sensitizes TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP. Free Radic Biol Med 2009;46:1639-1649.
-
(2009)
Free Radic Biol Med
, vol.46
, pp. 1639-1649
-
-
Lee, T.J.1
Um, H.J.2
Min Do, S.3
Park, J.W.4
Choi, K.S.5
Kwon, T.K.6
-
37
-
-
34548590339
-
Silibinin sensitizes human glioma cells to TRAILmediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin
-
Son YG, Kim EH, Kim JY, Kim SU, Kwon TK, Yoon AR, et al. Silibinin sensitizes human glioma cells to TRAILmediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin. Cancer Res 2007;67:8274-8284.
-
(2007)
Cancer Res
, vol.67
, pp. 8274-8284
-
-
Son, Y.G.1
Kim, E.H.2
Kim, J.Y.3
Kim, S.U.4
Kwon, T.K.5
Yoon, A.R.6
-
38
-
-
34948894931
-
Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL
-
Wagner KW, Punnoose EA, Januario T, Lawrence DA, Pitti RM, Lancaster K, et al. Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL. Nat Med 2007;13:1070-1077.
-
(2007)
Nat Med
, vol.13
, pp. 1070-1077
-
-
Wagner, K.W.1
Punnoose, E.A.2
Januario, T.3
Lawrence, D.A.4
Pitti, R.M.5
Lancaster, K.6
-
39
-
-
62749084512
-
Palmitoylation of the TRAIL receptor DR4 confers an effi cient TRAILinduced cell death signalling
-
2 p following 192
-
Rossin A, Derouet M, Abdel-Sater F, Hueber AO. Palmitoylation of the TRAIL receptor DR4 confers an effi cient TRAILinduced cell death signalling. Biochem J 2009;419:185-192, 2 p following 192.
-
(2009)
Biochem J
, vol.419
, pp. 185-192
-
-
Rossin, A.1
Derouet, M.2
Abdel-Sater, F.3
Hueber, A.O.4
-
40
-
-
0037201936
-
Role of sphingomyelinase and ceramide in modulating rafts: Do biophysical pro perties determine biologic outcome?
-
Cremesti AE, Goni FM, Kolesnick R. Role of sphingomyelinase and ceramide in modulating rafts: do biophysical pro perties determine biologic outcome? FEBS Lett 2002;531:47-53.
-
(2002)
FEBS Lett
, vol.531
, pp. 47-53
-
-
Cremesti, A.E.1
Goni, F.M.2
Kolesnick, R.3
-
41
-
-
29244467982
-
Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae
-
Martin S, Phillips DC, Szekely-Szucs K, Elghazi L, Desmots F, Houghton JA. Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae. Cancer Res 2005;65:11447-11458.
-
(2005)
Cancer Res
, vol.65
, pp. 11447-11458
-
-
Martin, S.1
Phillips, D.C.2
Szekely-Szucs, K.3
Elghazi, L.4
Desmots, F.5
Houghton, J.A.6
-
42
-
-
34748906001
-
Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts
-
Psahoulia FH, Drosopoulos KG, Doubravska L, Andera L, Pintzas A. Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts. Mol Cancer Ther 2007;6:2591-2599.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2591-2599
-
-
Psahoulia, F.H.1
Drosopoulos, K.G.2
Doubravska, L.3
Andera, L.4
Pintzas, A.5
-
43
-
-
34548713016
-
LY303511 amplifi es TRAIL-induced apoptosis in tumor cells by enhancing DR5 oligomerization DISC assembly, and mitochondrial permeabilization
-
Poh TW, Huang S, Hirpara JL, Pervaiz S. LY303511 amplifi es TRAIL-induced apoptosis in tumor cells by enhancing DR5 oligomerization, DISC assembly, and mitochondrial permeabilization. Cell Death Differ 2007;14:1813-1825.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1813-1825
-
-
Poh, T.W.1
Huang, S.2
Hirpara, J.L.3
Pervaiz, S.4
-
44
-
-
15744405757
-
Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy
-
Gajate C, Mollinedo F. Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy. J Biol Chem 2005;280: 11641-11647.
-
(2005)
J Biol Chem
, vol.280
, pp. 11641-11647
-
-
Gajate, C.1
Mollinedo, F.2
-
45
-
-
10644246821
-
Redistribution of CD95 DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells
-
Delmas D, Rebe C, Micheau O, Athias A, Gambert P, Grazide S, et al. Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells. Oncogene 2004;23:8979-8986.
-
(2004)
Oncogene
, vol.23
, pp. 8979-8986
-
-
Delmas, D.1
Rebe, C.2
Micheau, O.3
Athias, A.4
Gambert, P.5
Grazide, S.6
-
46
-
-
22044441646
-
Accelerated degradation of caspase-8 protein correlates with TRAIL resistance in a DLD1 human colon cancer cell line
-
Zhang L, Zhu H, Teraishi F, Davis JJ, Guo W, Fan Z, Fang B. Accelerated degradation of caspase-8 protein correlates with TRAIL resistance in a DLD1 human colon cancer cell line. Neoplasia 2005;7:594-602.
-
(2005)
Neoplasia
, vol.7
, pp. 594-602
-
-
Zhang, L.1
Zhu, H.2
Teraishi, F.3
Davis, J.J.4
Guo, W.5
Fan, Z.6
Fang, B.7
-
47
-
-
49849097056
-
Akt-mediated eminent expression of c-FLIP and Mcl-1 confers acquired resistance to TRAIL-induced cytotoxicity to lung cancer cells
-
Wang X, Chen W, Zeng W, Bai L, Tesfaigzi Y, Belinsky SA, Lin Y. Akt-mediated eminent expression of c-FLIP and Mcl-1 confers acquired resistance to TRAIL-induced cytotoxicity to lung cancer cells. Mol Cancer Ther 2008;7:1156-1163.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1156-1163
-
-
Wang, X.1
Chen, W.2
Zeng, W.3
Bai, L.4
Tesfaigzi, Y.5
Belinsky, S.A.6
Lin, Y.7
-
48
-
-
22544479422
-
FLIP is frequently expressed in endometrial carcinoma and has a role in resistance to TRAIL-induced apoptosis
-
Dolcet X, Llobet D, Pallares J, Rue M, Comella JX, Matias-Guiu X. FLIP is frequently expressed in endometrial carcinoma and has a role in resistance to TRAIL-induced apoptosis. Lab Invest 2005;85:885-894.
-
(2005)
Lab Invest
, vol.85
, pp. 885-894
-
-
Dolcet, X.1
Llobet, D.2
Pallares, J.3
Rue, M.4
Comella, J.X.5
Matias-Guiu, X.6
-
49
-
-
43749119838
-
Suppression of cFLIP is suffi cient to sensitize human melanoma cells to TRAIL-and CD95Lmediated apoptosis
-
Geserick P, Drewniok C, Hupe M, Haas TL, Diessenbacher P, Sprick MR, et al. Suppression of cFLIP is suffi cient to sensitize human melanoma cells to TRAIL-and CD95Lmediated apoptosis. Oncogene 2008;27:3211-3220.
-
(2008)
Oncogene
, vol.27
, pp. 3211-3220
-
-
Geserick, P.1
Drewniok, C.2
Hupe, M.3
Haas, T.L.4
Diessenbacher, P.5
Sprick, M.R.6
-
50
-
-
39949085436
-
Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and downregulation of c-FLIP
-
Kim YH, Jung EM, Lee TJ, Kim SH, Choi YH, Park JW, et a l. Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and downregulation of c-FLIP. Free Radic Biol Med 2008;44: 1055-1068.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 1055-1068
-
-
Kim, Y.H.1
Jung, E.M.2
Lee, T.J.3
Kim, S.H.4
Choi, Y.H.5
Park, J.W.6
-
51
-
-
38749133727
-
Proteasome inhibition blocks caspase-8 degradation and sensitizes prostate cancer cells to death receptor-mediated apoptosis
-
Thorpe JA, Christian PA, Schwarze SR. Proteasome inhibition blocks caspase-8 degradation and sensitizes prostate cancer cells to death receptor-mediated apoptosis. Prostate 2008;68:200-209.
-
(2008)
Prostate
, vol.68
, pp. 200-209
-
-
Thorpe, J.A.1
Christian, P.A.2
Schwarze, S.R.3
-
52
-
-
0034786019
-
BCL-2 BCL-X(L) sequester BH3 domain-only molecules preventing BAX-and BAK-mediated mitochondrial apoptosis
-
Cheng EH, Wei MC, Weiler S, Flavell RA, Mak TW, Lindsten T, Korsmeyer SJ. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX-and BAK-mediated mitochondrial apoptosis. Mol Cell 2001;8:705-711.
-
(2001)
Mol Cell
, vol.8
, pp. 705-711
-
-
Cheng, E.H.1
Wei, M.C.2
Weiler, S.3
Flavell, R.A.4
Mak, T.W.5
Lindsten, T.6
Korsmeyer, S.J.7
-
53
-
-
0037379739
-
Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factorrelated apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: Differential regulation of cytochrome c and Smac/DIABLO release
-
Kandasamy K, Srinivasula SM, Alnemri ES, Thompson CB, Korsmeyer SJ, Bryant JL, Srivastava RK. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factorrelated apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release. Cancer Res 2003;63:1712-1721.
-
(2003)
Cancer Res
, vol.63
, pp. 1712-1721
-
-
Kandasamy, K.1
Srinivasula, S.M.2
Alnemri, E.S.3
Thompson, C.B.4
Korsmeyer, S.J.5
Bryant, J.L.6
Srivastava, R.K.7
-
54
-
-
0037085935
-
Requirement of BAX for TRAIL/Apo2Linduced apoptosis of colorectal cancers: Synergism with sulindac-mediated inhibition of Bcl-x(L)
-
Ravi R, Bedi A. Requirement of BAX for TRAIL/Apo2Linduced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L). Cancer Res 2002;62: 1583-1587.
-
(2002)
Cancer Res
, vol.62
, pp. 1583-1587
-
-
Ravi, R.1
Bedi, A.2
-
55
-
-
0036141029
-
TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO
-
Deng Y, Lin Y, Wu X. TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO. Genes Dev 2002;16:33-45.
-
(2002)
Genes Dev
, vol.16
, pp. 33-45
-
-
Deng, Y.1
Lin, Y.2
Wu, X.3
-
56
-
-
0036131142
-
Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax
-
LeBlanc H, Lawrence D, Varfolomeev E, Totpal K, Morlan J, Schow P, et al. Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax. Nat Med 2002;8:274-281.
-
(2002)
Nat Med
, vol.8
, pp. 274-281
-
-
Leblanc, H.1
Lawrence, D.2
Varfolomeev, E.3
Totpal, K.4
Morlan, J.5
Schow, P.6
-
57
-
-
2442663096
-
Mcl-1 mediates tumor necrosis factorrelated apoptosis-inducing ligand resistance in human cholangiocarcinoma cells
-
Taniai M, Grambihler A, Higuchi H, Werneburg N, Bronk SF, Farrugia DJ, et al. Mcl-1 mediates tumor necrosis factorrelated apoptosis-inducing ligand resistance in human cholangiocarcinoma cells. Cancer Res 2004;64:3517-3524.
-
(2004)
Cancer Res
, vol.64
, pp. 3517-3524
-
-
Taniai, M.1
Grambihler, A.2
Higuchi, H.3
Werneburg, N.4
Bronk, S.F.5
Farrugia, D.J.6
-
58
-
-
14644437742
-
Mechanisms of resistance to TRAIL-induced apoptosis in cancer
-
Zhang L, Fang B. Mechanisms of resistance to TRAIL-induced apoptosis in cancer. Cancer Gene Ther 2005;12:228-237.
-
(2005)
Cancer Gene Ther
, vol.12
, pp. 228-237
-
-
Zhang, L.1
Fang, B.2
-
59
-
-
0034805181
-
Overexpression of BCL2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cells
-
Sun SY, Yue P, Zhou JY, Wang Y, Choi Kim HR, Lotan R, Wu GS. Overexpression of BCL2 blocks TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human lung cancer cells. Biochem Biophys Res Commun 2001;280: 788-797.
-
(2001)
Biochem Biophys Res Commun
, vol.280
, pp. 788-797
-
-
Sun, S.Y.1
Yue, P.2
Zhou, J.Y.3
Wang, Y.4
Choi Kim, H.R.5
Lotan, R.6
Wu, G.S.7
-
60
-
-
42349098051
-
BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells
-
Huang S, Sinicrope FA. BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells. Cancer Res 2008;68:2944-2951.
-
(2008)
Cancer Res
, vol.68
, pp. 2944-2951
-
-
Huang, S.1
Sinicrope, F.A.2
-
61
-
-
11144230279
-
Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells
-
Sinicrope FA, Penington RC, Tang XM. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells. Clin Cancer Res 2004;10: 8284-8292.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8284-8292
-
-
Sinicrope, F.A.1
Penington, R.C.2
Tang, X.M.3
-
62
-
-
63249129117
-
Daidzein overcomes TRAIL-resistance in malignant glioma cells by modulating the expression of the intrinsic apoptotic inhibitor, bcl-2
-
Siegelin MD, Gaiser T, Habel A, Siegelin Y. Daidzein overcomes TRAIL-resistance in malignant glioma cells by modulating the expression of the intrinsic apoptotic inhibitor, bcl-2. Neurosci Lett 2009;454:223-228.
-
(2009)
Neurosci Lett
, vol.454
, pp. 223-228
-
-
Siegelin, M.D.1
Gaiser, T.2
Habel, A.3
Siegelin, Y.4
-
63
-
-
0037500905
-
X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosisinducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: Sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO)
-
Ng CP, Bonavida B. X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosisinducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO). Mol Cancer Ther 2002;1:1051-1058.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 1051-1058
-
-
Ng, C.P.1
Bonavida, B.2
-
64
-
-
67349093843
-
Stable XIAP knockdown clones of HCT116 colon cancer cells are more sensitive to TRAIL, taxanes and irradiation in vitro
-
Connolly K, Mitter R, Muir M, Jodrell D, Guichard S. Stable XIAP knockdown clones of HCT116 colon cancer cells are more sensitive to TRAIL, taxanes and irradiation in vitro. Cancer Chemother Pharmacol 2009;64:307-316.
-
(2009)
Cancer Chemother Pharmacol
, vol.64
, pp. 307-316
-
-
Connolly, K.1
Mitter, R.2
Muir, M.3
Jodrell, D.4
Guichard, S.5
-
65
-
-
67650727602
-
Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation
-
Gill C, Dowling C, O'Neill AJ, Watson RW. Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation. Mol Cancer 2009;8:39.
-
(2009)
Mol Cancer
, vol.8
, pp. 39
-
-
Gill, C.1
Dowling, C.2
O'Neill, A.J.3
Watson, R.W.4
-
66
-
-
0035476255
-
Tumor necrosis factor-related apoptosis-inducing ligandinduced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria
-
Zhang XD, Zhang XY, Gray CP, Nguyen T, Hersey P. Tumor necrosis factor-related apoptosis-inducing ligandinduced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria. Cancer Res 2001;61:7339-7348.
-
(2001)
Cancer Res
, vol.61
, pp. 7339-7348
-
-
Zhang, X.D.1
Zhang, X.Y.2
Gray, C.P.3
Nguyen, T.4
Hersey, P.5
-
67
-
-
65549139431
-
Small molecule XIAP inhibitors enhance TRAILinduced apoptosis and antitumor activity in preclinical models of pancreatic carcinoma
-
Vogler M, Walczak H, Stadel D, Haas TL, Genze F, Jovanovic M, et al. Small molecule XIAP inhibitors enhance TRAILinduced apoptosis and antitumor activity in preclinical models of pancreatic carcinoma. Cancer Res 2009;69: 2425-2434.
-
(2009)
Cancer Res
, vol.69
, pp. 2425-2434
-
-
Vogler, M.1
Walczak, H.2
Stadel, D.3
Haas, T.L.4
Genze, F.5
Jovanovic, M.6
-
68
-
-
85042587668
-
Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance
-
Fakler M, Loeder S, Vogler M, Schneider K, Jeremias I, Debatin KM, Fulda S. Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance. Blood 2009;113:1710-1722.
-
(2009)
Blood
, vol.113
, pp. 1710-1722
-
-
Fakler, M.1
Loeder, S.2
Vogler, M.3
Schneider, K.4
Jeremias, I.5
Debatin, K.M.6
Fulda, S.7
-
69
-
-
4143082567
-
TRAIL promotes the survival, migration and proliferation of vascular smooth muscle cells
-
Secchiero P, Zerbinati C, Rimondi E, Corallini F, Milani D, Grill V, et al. TRAIL promotes the survival, migration and proliferation of vascular smooth muscle cells. Cell Mol Life Sci 2004;61:1965-1974.
-
(2004)
Cell Mol Life Sci
, vol.61
, pp. 1965-1974
-
-
Secchiero, P.1
Zerbinati, C.2
Rimondi, E.3
Corallini, F.4
Milani, D.5
Grill, V.6
-
70
-
-
13444278636
-
Rottlerin sensitizes glioma cells to TRAIL-induced apoptosis by inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP
-
Kim EH, Kim SU, Choi KS. Rottlerin sensitizes glioma cells to TRAIL-induced apoptosis by inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP. Oncogene 2005;24:838-849.
-
(2005)
Oncogene
, vol.24
, pp. 838-849
-
-
Kim, E.H.1
Kim, S.U.2
Choi, K.S.3
-
71
-
-
0842329845
-
Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP
-
Kim EH, Kim SU, Shin DY, Choi KS. Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP. Oncogene 2004;23:446-456.
-
(2004)
Oncogene
, vol.23
, pp. 446-456
-
-
Kim, E.H.1
Kim, S.U.2
Shin, D.Y.3
Choi, K.S.4
-
72
-
-
56249131797
-
The fl avonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivin
-
Siegelin MD, Reuss DE, Habel A, Herold-Mende C, von Deimling A. The fl avonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivin. Mol Cancer Ther 2008;7:3566-3574.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3566-3574
-
-
Siegelin, M.D.1
Reuss, D.E.2
Habel, A.3
Herold-Mende, C.4
Von Deimling, A.5
-
73
-
-
65949095390
-
Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells
-
Siegelin MD, Reuss DE, Habel A, Rami A, von Deimling A. Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells. Neuro Oncol 2009;11:122-131.
-
(2009)
Neuro Oncol
, vol.11
, pp. 122-131
-
-
Siegelin, M.D.1
Reuss, D.E.2
Habel, A.3
Rami, A.4
Von Deimling, A.5
-
75
-
-
4544359913
-
Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species
-
Starkov AA, Fiskum G, Chinopoulos C, Lorenzo BJ, Browne SE, Patel MS, Beal MF. Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species. J Neurosci 2004;24:7779-7788.
-
(2004)
J Neurosci
, vol.24
, pp. 7779-7788
-
-
Starkov, A.A.1
Fiskum, G.2
Chinopoulos, C.3
Lorenzo, B.J.4
Browne, S.E.5
Patel, M.S.6
Beal, M.F.7
-
76
-
-
33749047437
-
Localizing NADPH oxidase-derived ROS
-
Ushio-Fukai M. Localizing NADPH oxidase-derived ROS. Sci STKE 2006;2006:re8.
-
(2006)
Sci STKE
, vol.2006
-
-
Ushio-Fukai, M.1
-
77
-
-
31744443116
-
Lipid raft clustering and redox signaling platform formation in coronary arterial endothelial cells
-
Zhang AY, Yi F, Zhang G, Gulbins E, Li PL. Lipid raft clustering and redox signaling platform formation in coronary arterial endothelial cells. Hypertension 2006;47: 74-80.
-
(2006)
Hypertension
, vol.47
, pp. 74-80
-
-
Zhang, A.Y.1
Yi, F.2
Zhang, G.3
Gulbins, E.4
Li, P.L.5
-
78
-
-
77949593677
-
Targeting and regulation of reactive oxygen species generation by Nox family NADPH oxidases
-
Leto TL, Morand S, Hurt D, Ueyama T. Targeting and regulation of reactive oxygen species generation by Nox family NADPH oxidases. Antioxid Redox Signal 2009;11:2607-2619.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 2607-2619
-
-
Leto, T.L.1
Morand, S.2
Hurt, D.3
Ueyama, T.4
-
79
-
-
70449715463
-
Reactive oxygen species and peroxisomes: Struggling for balance
-
Bonekamp NA, Volkl A, Fahimi HD, Schrader M. Reactive oxygen species and peroxisomes: struggling for balance. Biofactors 2009;35:346-355.
-
(2009)
Biofactors
, vol.35
, pp. 346-355
-
-
Bonekamp, N.A.1
Volkl, A.2
Fahimi, H.D.3
Schrader, M.4
-
80
-
-
4444268690
-
Mechanisms that regulate production of reactive oxygen species by cytochrome P450
-
Zangar RC, Davydov DR, Verma S. Mechanisms that regulate production of reactive oxygen species by cytochrome P450. Toxicol Appl Pharmacol 2004;199:316-331.
-
(2004)
Toxicol Appl Pharmacol
, vol.199
, pp. 316-331
-
-
Zangar, R.C.1
Davydov, D.R.2
Verma, S.3
-
81
-
-
0029187630
-
Diversity of glutathione peroxidases
-
Ursini F, Maiorino M, Brigelius-Flohe R, Aumann KD, Roveri A, Schomburg D, Flohe L. Diversity of glutathione peroxidases. Methods Enzymol 1995;252:38-53.
-
(1995)
Methods Enzymol
, vol.252
, pp. 38-53
-
-
Ursini, F.1
Maiorino, M.2
Brigelius-Flohe, R.3
Aumann, K.D.4
Roveri, A.5
Schomburg, D.6
Flohe, L.7
-
82
-
-
0016808562
-
Purifi cation and characterization of the fl avoenzyme glutathione reductase from rat liver
-
Carlberg I, Mannervik B. Purifi cation and characterization of the fl avoenzyme glutathione reductase from rat liver. J Biol Chem 1975;250:5475-5480.
-
(1975)
J Biol Chem
, vol.250
, pp. 5475-5480
-
-
Carlberg, I.1
Mannervik, B.2
-
83
-
-
0034652113
-
Thioredoxin reductase
-
Mustacich D, Powis G. Thioredoxin reductase. Biochem J 2000;346(Pt 1):1-8.
-
(2000)
Biochem J
, vol.346
, Issue.PART 1
, pp. 1-8
-
-
Mustacich, D.1
Powis, G.2
-
84
-
-
0033775891
-
Physiological functions of thioredoxin and thioredoxin reductase
-
Arner ES, Holmgren A. Physiological functions of thioredoxin and thioredoxin reductase. Eur J Biochem 2000;267: 6102-6109.
-
(2000)
Eur J Biochem
, vol.267
, pp. 6102-6109
-
-
Arner, E.S.1
Holmgren, A.2
-
85
-
-
79953147660
-
Human catalase: Looking for complete identity
-
Goyal MM, Basak A. Human catalase: looking for complete identity. Protein Cell 2010;1:888-897.
-
(2010)
Protein Cell
, vol.1
, pp. 888-897
-
-
Goyal, M.M.1
Basak, A.2
-
86
-
-
0032955318
-
Reactive oxygen intermediates regulate cellular response to apoptotic stimuli: An hypothesis
-
Clement MV, Pervaiz S. Reactive oxygen intermediates regulate cellular response to apoptotic stimuli: an hypothesis. Free Radic Res 1999;30:247-252.
-
(1999)
Free Radic Res
, vol.30
, pp. 247-252
-
-
Clement, M.V.1
Pervaiz, S.2
-
87
-
-
0026636441
-
Free radicals, antioxidants, and human disease: Where are we now?
-
Halliwell B, Gutteridge JM, Cross CE. Free radicals, antioxidants, and human disease: where are we now? J Lab Clin Med 1992;119:598-620.
-
(1992)
J Lab Clin Med
, vol.119
, pp. 598-620
-
-
Halliwell, B.1
Gutteridge, J.M.2
Cross, C.E.3
-
88
-
-
0034797708
-
Intracellular superoxide and hydrogen peroxide concentrations: A critical balance that determines survival or death
-
Clement MV, Pervaiz S. Intracellular superoxide and hydrogen peroxide concentrations: a critical balance that determines survival or death. Redox Rep 2001;6:211-224.
-
(2001)
Redox Rep
, vol.6
, pp. 211-224
-
-
Clement, M.V.1
Pervaiz, S.2
-
89
-
-
0036086130
-
Free radicals in the physiological control of cell function
-
Droge W. Free radicals in the physiological control of cell function. Physiol Rev 2002;82:47-95.
-
(2002)
Physiol Rev
, vol.82
, pp. 47-95
-
-
Droge, W.1
-
90
-
-
1342347866
-
Pro-oxidant activity of low doses of resveratrol inhibits hydrogen peroxide-induced apoptosis
-
Ahmad KA, Clement MV, Pervaiz S. Pro-oxidant activity of low doses of resveratrol inhibits hydrogen peroxide-induced apoptosis. Ann N Y Acad Sci 2003;1010:365-373.
-
(2003)
Ann N y Acad Sci
, vol.1010
, pp. 365-373
-
-
Ahmad, K.A.1
Clement, M.V.2
Pervaiz, S.3
-
91
-
-
0242524405
-
Decrease in intracellular superoxide sensitizes Bcl-2-overexpressing tumor cells to receptor and drug-induced apoptosis independent of the mitochondria
-
Clement MV, Hirpara JL, Pervaiz S. Decrease in intracellular superoxide sensitizes Bcl-2-overexpressing tumor cells to receptor and drug-induced apoptosis independent of the mitochondria. Cell Death Differ 2003;10:1273-1285.
-
(2003)
Cell Death Differ
, vol.10
, pp. 1273-1285
-
-
Clement, M.V.1
Hirpara, J.L.2
Pervaiz, S.3
-
92
-
-
0030065418
-
Superoxide anion is a natural inhibitor of FAS-mediated cell death
-
Clement MV, Stamenkovic I. Superoxide anion is a natural inhibitor of FAS-mediated cell death. EMBO J 1996;15: 216-225.
-
(1996)
EMBO J
, vol.15
, pp. 216-225
-
-
Clement, M.V.1
Stamenkovic, I.2
-
93
-
-
0032573495
-
Apoptosis induced by hydrogen peroxide is mediated by decreased superoxide anion concentration and reduction of intracellular milieu
-
Clement MV, Ponton A, Pervaiz S. Apoptosis induced by hydrogen peroxide is mediated by decreased superoxide anion concentration and reduction of intracellular milieu. FEBS Lett 1998;440:13-18.
-
(1998)
FEBS Lett
, vol.440
, pp. 13-18
-
-
Clement, M.V.1
Ponton, A.2
Pervaiz, S.3
-
94
-
-
7444223594
-
Hydrogen peroxide-mediated cytosolic acidification is a signal for mitochondrial translocation of Bax during drug-induced apoptosis of tumor cells
-
Ahmad KA, Iskandar KB, Hirpara JL, Clement MV, Pervaiz S. Hydrogen peroxide-mediated cytosolic acidification is a signal for mitochondrial translocation of Bax during drug-induced apoptosis of tumor cells. Cancer Res 2004;64:7867-7878.
-
(2004)
Cancer Res
, vol.64
, pp. 7867-7878
-
-
Ahmad, K.A.1
Iskandar, K.B.2
Hirpara, J.L.3
Clement, M.V.4
Pervaiz, S.5
-
95
-
-
0035808388
-
Intracellular acidifi cation triggered by mitochondrial-derived hydrogen peroxide is an effector mechanism for drug-induced apoptosis in tumor cells
-
Hirpara JL, Clement MV, Pervaiz S. Intracellular acidifi cation triggered by mitochondrial-derived hydrogen peroxide is an effector mechanism for drug-induced apoptosis in tumor cells. J Biol Chem 2001;276:514-521.
-
(2001)
J Biol Chem
, vol.276
, pp. 514-521
-
-
Hirpara, J.L.1
Clement, M.V.2
Pervaiz, S.3
-
96
-
-
0029763774
-
Hydrogen peroxide induces complex formation of SHC-Grb2-SOS with receptor tyrosine kinase and activates Ras and extracellular signal-regulated protein kinases group of mitogen-activated protein kinases
-
Rao GN. Hydrogen peroxide induces complex formation of SHC-Grb2-SOS with receptor tyrosine kinase and activates Ras and extracellular signal-regulated protein kinases group of mitogen-activated protein kinases. Oncogene 1996;13: 713-719.
-
(1996)
Oncogene
, vol.13
, pp. 713-719
-
-
Rao, G.N.1
-
97
-
-
33947250704
-
Phosphorylation of the survival kinase Akt by superoxide is dependent on an ascorbatereversible oxidation of PTEN
-
Lim S, Clement MV. Phosphorylation of the survival kinase Akt by superoxide is dependent on an ascorbatereversible oxidation of PTEN. Free Radic Biol Med 2007;42:1178-1192.
-
(2007)
Free Radic Biol Med
, vol.42
, pp. 1178-1192
-
-
Lim, S.1
Clement, M.V.2
-
98
-
-
0035959749
-
Activation of the RacGTPase inhibits apoptosis in human tumor cells
-
Pervaiz S, Cao J, Chao OS, Chin YY, Clement MV. Activation of the RacGTPase inhibits apoptosis in human tumor cells. Oncogene 2001;20:6263-6268.
-
(2001)
Oncogene
, vol.20
, pp. 6263-6268
-
-
Pervaiz, S.1
Cao, J.2
Chao, O.S.3
Chin, Y.Y.4
Clement, M.V.5
-
99
-
-
50949098870
-
Proteasome inhibitors enhance TRAIL-induced apoptosis through the intronic regulation of DR5: Involvement of NF-kappa B and reactive oxygen species-mediated p53 activation
-
Chen JJ, Chou CW, Chang YF, Chen CC. Proteasome inhibitors enhance TRAIL-induced apoptosis through the intronic regulation of DR5: involvement of NF-kappa B and reactive oxygen species-mediated p53 activation. J Immunol 2008;180: 8030-8039.
-
(2008)
J Immunol
, vol.180
, pp. 8030-8039
-
-
Chen, J.J.1
Chou, C.W.2
Chang, Y.F.3
Chen, C.C.4
-
100
-
-
78751522712
-
ROS and CHOP are critical for dibenzylideneacetone to sensitize tumor cells to TRAIL through induction of death receptors and downregulation of cell survival proteins
-
Prasad S, Yadav VR, Ravindran J, Aggarwal BB. ROS and CHOP are critical for dibenzylideneacetone to sensitize tumor cells to TRAIL through induction of death receptors and downregulation of cell survival proteins. Cancer Res;71: 538-549.
-
Cancer Res
, vol.71
, pp. 538-549
-
-
Prasad, S.1
Yadav, V.R.2
Ravindran, J.3
Aggarwal, B.B.4
-
101
-
-
84863012720
-
Death receptors 4 and 5 activate Nox1 NADPH oxidase through ribofl avin kinase to induce reactive oxygen species-mediated apoptotic cell death
-
Park KJ, Lee CH, Kim A, Jeong KJ, Kim CH, Kim YS. Death receptors 4 and 5 activate Nox1 NADPH oxidase through ribofl avin kinase to induce reactive oxygen species-mediated apoptotic cell death. J Biol Chem 2012;287:3313-3325.
-
(2012)
J Biol Chem
, vol.287
, pp. 3313-3325
-
-
Park, K.J.1
Lee, C.H.2
Kim, A.3
Jeong, K.J.4
Kim, C.H.5
Kim, Y.S.6
|