메뉴 건너뛰기




Volumn 227, Issue 4, 2012, Pages 456-469

Tumour suppressor Fus1 provides a molecular link between inflammatory response and mitochondrial homeostasis

Author keywords

asbestos; DN T cells; Fus1; inflammatory response; mitochondria; mitochondrial membrane potential; ROS; UCP2

Indexed keywords

ASBESTOS; GAMMA INTERFERON; HISTONE H2AX; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; MANGANESE SUPEROXIDE DISMUTASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NUCLEAR PROTEIN; PEROXIREDOXIN 1; PROTEIN GAMMA H2AX; RANTES; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 2;

EID: 84863715552     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4039     Document Type: Article
Times cited : (18)

References (93)
  • 1
    • 78049370987 scopus 로고    scopus 로고
    • Oxidative stress, inflammation, and cancer: How are they linked?
    • Reuter S, Gupta SC, Chaturvedi MM, et al., Oxidative stress, inflammation, and cancer: how are they linked? Free Radic Biol Med 2010; 49 (11): 1603-1616.
    • (2010) Free Radic Biol Med , vol.49 , Issue.11 , pp. 1603-1616
    • Reuter, S.1    Gupta, S.C.2    Chaturvedi, M.M.3
  • 2
    • 79952712223 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species drive proinflammatory cytokine production
    • Naik E, Dixit VM,. Mitochondrial reactive oxygen species drive proinflammatory cytokine production. J Exp Med 2011; 208: 417-420.
    • (2011) J Exp Med , vol.208 , pp. 417-420
    • Naik, E.1    Dixit, V.M.2
  • 3
    • 79957597757 scopus 로고    scopus 로고
    • Mitochondria in innate immune responses
    • West AP, Shadel GS, Ghosh S,. Mitochondria in innate immune responses. Nat Rev Immunol 2011; 11: 389-402.
    • (2011) Nat Rev Immunol , vol.11 , pp. 389-402
    • West, A.P.1    Shadel, G.S.2    Ghosh, S.3
  • 4
    • 79151479868 scopus 로고    scopus 로고
    • Elevated mitochondrial superoxide disrupts normal T cell development, impairing adaptive immune responses to an influenza challenge
    • Case AJ, McGill JL, Tygrett LT, et al., Elevated mitochondrial superoxide disrupts normal T cell development, impairing adaptive immune responses to an influenza challenge. Free Radic Biol Med 2011; 50: 448-458.
    • (2011) Free Radic Biol Med , vol.50 , pp. 448-458
    • Case, A.J.1    McGill, J.L.2    Tygrett, L.T.3
  • 5
    • 79953068336 scopus 로고    scopus 로고
    • Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation
    • Krysko DV, Agostinis P, Krysko O, et al., Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation. Trends Immunol 2011; 32: 157-164.
    • (2011) Trends Immunol , vol.32 , pp. 157-164
    • Krysko, D.V.1    Agostinis, P.2    Krysko, O.3
  • 6
    • 33947663485 scopus 로고    scopus 로고
    • Autoimmunity, spontaneous tumourigenesis, and IL-15 insufficiency in mice with a targeted disruption of the tumour suppressor gene Fus1
    • Ivanova AV, Ivanov SV, Pascal V, et al., Autoimmunity, spontaneous tumourigenesis, and IL-15 insufficiency in mice with a targeted disruption of the tumour suppressor gene Fus1. J Pathol 2007; 211: 591-601.
    • (2007) J Pathol , vol.211 , pp. 591-601
    • Ivanova, A.V.1    Ivanov, S.V.2    Pascal, V.3
  • 7
    • 19244370711 scopus 로고    scopus 로고
    • High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints
    • Wistuba II, Behrens C, Virmani AK, et al., High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints. Cancer Res 2000; 60: 1949-1960.
    • (2000) Cancer Res , vol.60 , pp. 1949-1960
    • Wistuba, I.I.1    Behrens, C.2    Virmani, A.K.3
  • 8
    • 70749143916 scopus 로고    scopus 로고
    • Mechanisms of FUS1/TUSC2 deficiency in mesothelioma and its tumorigenic transcriptional effects
    • Ivanova AV, Ivanov SV, Prudkin L, et al., Mechanisms of FUS1/TUSC2 deficiency in mesothelioma and its tumorigenic transcriptional effects. Mol Cancer 2009; 8: 91-107.
    • (2009) Mol Cancer , vol.8 , pp. 91-107
    • Ivanova, A.V.1    Ivanov, S.V.2    Prudkin, L.3
  • 9
    • 40749138663 scopus 로고    scopus 로고
    • Loss and reduction of FUS1 protein expression is a frequent phenomenon in the pathogenesis of lung cancer
    • Prudkin L, Behrens C, Liu DD, et al., Loss and reduction of FUS1 protein expression is a frequent phenomenon in the pathogenesis of lung cancer. Clin Cancer Res 2008; 14: 41-47.
    • (2008) Clin Cancer Res , vol.14 , pp. 41-47
    • Prudkin, L.1    Behrens, C.2    Liu, D.D.3
  • 10
    • 0035959880 scopus 로고    scopus 로고
    • 1 arrest and growth inhibition of lung cancer cells
    • 1 arrest and growth inhibition of lung cancer cells. Oncogene 2001; 20: 6258-6262.
    • (2001) Oncogene , vol.20 , pp. 6258-6262
    • Kondo, M.1    Ji, L.2    Kamibayashi, C.3
  • 11
    • 2342472611 scopus 로고    scopus 로고
    • Myristoylation of the fus1 protein is required for tumor suppression in human lung cancer cells
    • Uno F, Sasaki J, Nishizaki M, et al., Myristoylation of the fus1 protein is required for tumor suppression in human lung cancer cells. Cancer Res 2004; 64: 2969-2976.
    • (2004) Cancer Res , vol.64 , pp. 2969-2976
    • Uno, F.1    Sasaki, J.2    Nishizaki, M.3
  • 12
    • 8444251047 scopus 로고    scopus 로고
    • Liposomal vector mediated delivery of the 3p FUS1 gene demonstrates potent antitumor activity against human lung cancer in vivo
    • Ito I, Ji L, Tanaka F, et al., Liposomal vector mediated delivery of the 3p FUS1 gene demonstrates potent antitumor activity against human lung cancer in vivo. Cancer Gene Ther 2004; 11: 733-739.
    • (2004) Cancer Gene Ther , vol.11 , pp. 733-739
    • Ito, I.1    Ji, L.2    Tanaka, F.3
  • 13
    • 41749104248 scopus 로고    scopus 로고
    • Tumor suppressor FUS1 signaling pathway
    • Ji L, Roth JA,. Tumor suppressor FUS1 signaling pathway. J Thorac Oncol 2008; 3: 327-330.
    • (2008) J Thorac Oncol , vol.3 , pp. 327-330
    • Ji, L.1    Roth, J.A.2
  • 14
    • 35548969446 scopus 로고    scopus 로고
    • Oncogenic activation of c-Abl in non-small cell lung cancer cells lacking FUS1 expression: Inhibition of c-Abl by the tumor suppressor gene product Fus1
    • Lin J, Sun T, Ji L, et al., Oncogenic activation of c-Abl in non-small cell lung cancer cells lacking FUS1 expression: inhibition of c-Abl by the tumor suppressor gene product Fus1. Oncogene 2007; 26: 6989-6996.
    • (2007) Oncogene , vol.26 , pp. 6989-6996
    • Lin, J.1    Sun, T.2    Ji, L.3
  • 15
    • 33846659089 scopus 로고    scopus 로고
    • Synergistic tumor suppression by coexpression of FUS1 and p53 is associated with down-regulation of murine double minute-2 and activation of the apoptotic protease-activating factor 1-dependent apoptotic pathway in human non-small cell lung cancer cells
    • Deng WG, Kawashima H, Wu G, et al., Synergistic tumor suppression by coexpression of FUS1 and p53 is associated with down-regulation of murine double minute-2 and activation of the apoptotic protease-activating factor 1-dependent apoptotic pathway in human non-small cell lung cancer cells. Cancer Res 2007; 67: 709-717.
    • (2007) Cancer Res , vol.67 , pp. 709-717
    • Deng, W.G.1    Kawashima, H.2    Wu, G.3
  • 16
    • 37149046928 scopus 로고    scopus 로고
    • Enhancement of antitumor activity of cisplatin in human lung cancer cells by tumor suppressor FUS1
    • Deng WG, Wu G, Ueda K, et al., Enhancement of antitumor activity of cisplatin in human lung cancer cells by tumor suppressor FUS1. Cancer Gene Ther 2008; 15: 29-39.
    • (2008) Cancer Gene Ther , vol.15 , pp. 29-39
    • Deng, W.G.1    Wu, G.2    Ueda, K.3
  • 17
    • 28544446058 scopus 로고    scopus 로고
    • Mitochondrial tumour suppressors: A genetic and biochemical update
    • Gottlieb E, Tomlinson IP,. Mitochondrial tumour suppressors: a genetic and biochemical update. Nat Rev Cancer 2005; 5: 857-866.
    • (2005) Nat Rev Cancer , vol.5 , pp. 857-866
    • Gottlieb, E.1    Tomlinson, I.P.2
  • 18
    • 69249123718 scopus 로고    scopus 로고
    • Proline oxidase functions as a mitochondrial tumor suppressor in human cancers
    • Liu Y, Borchert GL, Donald SP, et al., Proline oxidase functions as a mitochondrial tumor suppressor in human cancers. Cancer Res 2009; 69: 6414-6422.
    • (2009) Cancer Res , vol.69 , pp. 6414-6422
    • Liu, Y.1    Borchert, G.L.2    Donald, S.P.3
  • 19
    • 74049094817 scopus 로고    scopus 로고
    • SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress
    • Kim HS, Patel K, Muldoon-Jacobs K, et al., SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. Cancer Cell 17: 41-52.
    • Cancer Cell , vol.17 , pp. 41-52
    • Kim, H.S.1    Patel, K.2    Muldoon-Jacobs, K.3
  • 20
    • 24144461689 scopus 로고    scopus 로고
    • Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-ΰB and IRF 3
    • Seth RB, Sun L, Ea CK, et al., Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-ΰB and IRF 3. Cell 2005; 122: 669-682.
    • (2005) Cell , vol.122 , pp. 669-682
    • Seth, R.B.1    Sun, L.2    Ea, C.K.3
  • 21
    • 79961133270 scopus 로고    scopus 로고
    • MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response
    • Hou F, Sun L, Zheng H, et al., MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response. Cell 2011; 146 (3): 448-461.
    • (2011) Cell , vol.146 , Issue.3 , pp. 448-461
    • Hou, F.1    Sun, L.2    Zheng, H.3
  • 22
    • 79955161193 scopus 로고    scopus 로고
    • Mitochondria: Sovereign of inflammation?
    • Tschopp J,. Mitochondria: Sovereign of inflammation? Eur J Immunol 2011; 41: 1196-1202.
    • (2011) Eur J Immunol , vol.41 , pp. 1196-1202
    • Tschopp, J.1
  • 23
    • 79955515913 scopus 로고    scopus 로고
    • 2+ and ROS take center stage to orchestrate TNFα-mediated inflammatory responses
    • 2+ and ROS take center stage to orchestrate TNFα-mediated inflammatory responses. J Clin Invest; 121: 1683-1685.
    • J Clin Invest , vol.121 , pp. 1683-1685
    • Dada, L.A.1    Sznajder, J.I.2
  • 24
    • 0037403861 scopus 로고    scopus 로고
    • Multiple roles of oxidants in the pathogenesis of asbestos-induced diseases
    • Shukla A, Gulumian M, Hei TK, et al., Multiple roles of oxidants in the pathogenesis of asbestos-induced diseases. Free Radic Biol Med 2003; 34: 1117-1129.
    • (2003) Free Radic Biol Med , vol.34 , pp. 1117-1129
    • Shukla, A.1    Gulumian, M.2    Hei, T.K.3
  • 25
    • 46749153312 scopus 로고    scopus 로고
    • Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study
    • Poland CA, Duffin R, Kinloch I, et al., Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat Nanotechnol 2008; 3: 423-428.
    • (2008) Nat Nanotechnol , vol.3 , pp. 423-428
    • Poland, C.A.1    Duffin, R.2    Kinloch, I.3
  • 26
    • 40349113411 scopus 로고    scopus 로고
    • +/- mouse by intraperitoneal application of multi-wall carbon nanotube
    • +/- mouse by intraperitoneal application of multi-wall carbon nanotube. J Toxicol Sci 2008; 33: 105-116.
    • (2008) J Toxicol Sci , vol.33 , pp. 105-116
    • Takagi, A.1    Hirose, A.2    Nishimura, T.3
  • 27
    • 80053320089 scopus 로고    scopus 로고
    • Long, needle-like carbon nanotubes and asbestos activate the NLRP3 inflammasome through a similar mechanism
    • Palomaki J, Valimaki E, Sund J, et al., Long, needle-like carbon nanotubes and asbestos activate the NLRP3 inflammasome through a similar mechanism. ACS Nano 2011; 5: 6861-6870.
    • (2011) ACS Nano , vol.5 , pp. 6861-6870
    • Palomaki, J.1    Valimaki, E.2    Sund, J.3
  • 28
    • 79959263560 scopus 로고    scopus 로고
    • Osteopontin modulates inflammation, mucin production, and gene expression signatures after inhalation of asbestos in a murine model of fibrosis
    • Sabo-Attwood T, Ramos-Nino ME, Eugenia-Ariza M, et al., Osteopontin modulates inflammation, mucin production, and gene expression signatures after inhalation of asbestos in a murine model of fibrosis. Am J Pathol 2011; 178: 1975-1985.
    • (2011) Am J Pathol , vol.178 , pp. 1975-1985
    • Sabo-Attwood, T.1    Ramos-Nino, M.E.2    Eugenia-Ariza, M.3
  • 29
    • 77956247365 scopus 로고    scopus 로고
    • Inflammation precedes the development of human malignant mesotheliomas in a SCID mouse xenograft model
    • Hillegass JM, Shukla A, Lathrop SA, et al., Inflammation precedes the development of human malignant mesotheliomas in a SCID mouse xenograft model. Ann NY Acad Sci 2010; 1203: 7-14.
    • (2010) Ann NY Acad Sci , vol.1203 , pp. 7-14
    • Hillegass, J.M.1    Shukla, A.2    Lathrop, S.A.3
  • 30
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • Dostert C, Petrilli V, Van Bruggen R, et al., Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 2008; 320: 674-677.
    • (2008) Science , vol.320 , pp. 674-677
    • Dostert, C.1    Petrilli, V.2    Van Bruggen, R.3
  • 31
    • 0031799746 scopus 로고    scopus 로고
    • Mechanisms in the pathogenesis of asbestosis and silicosis
    • Mossman BT, Churg A,. Mechanisms in the pathogenesis of asbestosis and silicosis. Am J Respir Crit Care Med 1998; 157: 1666-1680.
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 1666-1680
    • Mossman, B.T.1    Churg, A.2
  • 32
    • 0037823496 scopus 로고    scopus 로고
    • Soluble ICAM-1, MCP-1, and MIP-2 protein secretion by rat pleural mesothelial cells following exposure to amosite asbestos
    • Hill GD, Mangum JB, Moss OR, et al., Soluble ICAM-1, MCP-1, and MIP-2 protein secretion by rat pleural mesothelial cells following exposure to amosite asbestos. Exp Lung Res 2003; 29: 277-290.
    • (2003) Exp Lung Res , vol.29 , pp. 277-290
    • Hill, G.D.1    Mangum, J.B.2    Moss, O.R.3
  • 33
    • 0031217344 scopus 로고    scopus 로고
    • Pleural macrophage recruitment and activation in asbestos-induced pleural injury
    • Choe N, Tanaka S, Xia W, et al., Pleural macrophage recruitment and activation in asbestos-induced pleural injury. Environ Health Perspect 1997; 105 (suppl 5): 1257-1260.
    • (1997) Environ Health Perspect , vol.105 , Issue.SUPPL. 5 , pp. 1257-1260
    • Choe, N.1    Tanaka, S.2    Xia, W.3
  • 34
    • 77955446834 scopus 로고    scopus 로고
    • Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation
    • Yang H, Rivera Z, Jube S, et al., Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation. Proc Natl Acad Sci USA 2010; 107: 12611-12616.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 12611-12616
    • Yang, H.1    Rivera, Z.2    Jube, S.3
  • 35
    • 77952317021 scopus 로고    scopus 로고
    • Asbestos, carbon nanotubes and the pleural mesothelium: A review of the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma
    • Donaldson K, Murphy FA, Duffin R, et al., Asbestos, carbon nanotubes and the pleural mesothelium: a review of the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma. Part Fibre Toxicol 2010; 7: 5.
    • (2010) Part Fibre Toxicol , vol.7 , pp. 5
    • Donaldson, K.1    Murphy, F.A.2    Duffin, R.3
  • 36
    • 0033961085 scopus 로고    scopus 로고
    • Pulmonary and intraperitoneal inflammation induced by cellulose fibres
    • Cullen RT, Searl A, Miller BG, et al., Pulmonary and intraperitoneal inflammation induced by cellulose fibres. J Appl Toxicol 2000; 20: 49-60.
    • (2000) J Appl Toxicol , vol.20 , pp. 49-60
    • Cullen, R.T.1    Searl, A.2    Miller, B.G.3
  • 37
    • 5444256371 scopus 로고    scopus 로고
    • Inflammation as a tumor promoter in cancer induction
    • Philip M, Rowley DA, Schreiber H,. Inflammation as a tumor promoter in cancer induction. Semin Cancer Biol 2004; 14: 433-439.
    • (2004) Semin Cancer Biol , vol.14 , pp. 433-439
    • Philip, M.1    Rowley, D.A.2    Schreiber, H.3
  • 38
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens LM, Werb Z,. Inflammation and cancer. Nature 2002; 420: 860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 39
    • 33947607214 scopus 로고    scopus 로고
    • Inflammation and cancer: A failure of resolution?
    • Lawrence T,. Inflammation and cancer: a failure of resolution? Trends Pharmacol Sci 2007; 28: 162-165.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 162-165
    • Lawrence, T.1
  • 41
    • 0033843374 scopus 로고    scopus 로고
    • Increased phosphorylated extracellular signal-regulated kinase immunoreactivity associated with proliferative and morphologic lung alterations after chrysotile asbestos inhalation in mice
    • Robledo RF, Buder-Hoffmann SA, Cummins AB, et al., Increased phosphorylated extracellular signal-regulated kinase immunoreactivity associated with proliferative and morphologic lung alterations after chrysotile asbestos inhalation in mice. Am J Pathol 2000; 156: 1307-1316.
    • (2000) Am J Pathol , vol.156 , pp. 1307-1316
    • Robledo, R.F.1    Buder-Hoffmann, S.A.2    Cummins, A.B.3
  • 42
    • 0037370828 scopus 로고    scopus 로고
    • Persistent localization of activated extracellular signal-regulated kinases (ERK1/2) is epithelial cell-specific in an inhalation model of asbestosis
    • Cummins AB, Palmer C, Mossman BT, et al., Persistent localization of activated extracellular signal-regulated kinases (ERK1/2) is epithelial cell-specific in an inhalation model of asbestosis. Am J Pathol 2003; 162: 713-720.
    • (2003) Am J Pathol , vol.162 , pp. 713-720
    • Cummins, A.B.1    Palmer, C.2    Mossman, B.T.3
  • 43
    • 42949162548 scopus 로고    scopus 로고
    • Targeting the MEK1 cascade in lung epithelium inhibits proliferation and fibrogenesis by asbestos
    • Manning CB, Sabo-Attwood T, Robledo RF, et al., Targeting the MEK1 cascade in lung epithelium inhibits proliferation and fibrogenesis by asbestos. Am J Respir Cell Mol Biol 2008; 38: 618-626.
    • (2008) Am J Respir Cell Mol Biol , vol.38 , pp. 618-626
    • Manning, C.B.1    Sabo-Attwood, T.2    Robledo, R.F.3
  • 44
    • 34447542043 scopus 로고    scopus 로고
    • Asbestos-mediated CREB phosphorylation is regulated by protein kinase A and extracellular signal-regulated kinases 1/2
    • Barlow CA, Barrett TF, Shukla A, et al., Asbestos-mediated CREB phosphorylation is regulated by protein kinase A and extracellular signal-regulated kinases 1/2. Am J Physiol Lung Cell Mol Physiol 2007; 292: L1361-1369.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.292
    • Barlow, C.A.1    Barrett, T.F.2    Shukla, A.3
  • 45
    • 0030920424 scopus 로고    scopus 로고
    • Switching gears during T-cell maturation: RANTES and late transcription
    • Ortiz BD, Nelson PJ, Krensky AM,. Switching gears during T-cell maturation: RANTES and late transcription. Immunol Today 1997; 18: 468-471.
    • (1997) Immunol Today , vol.18 , pp. 468-471
    • Ortiz, B.D.1    Nelson, P.J.2    Krensky, A.M.3
  • 46
    • 0033653644 scopus 로고    scopus 로고
    • Transcriptional regulation of RANTES expression in T lymphocytes
    • Song A, Nikolcheva T, Krensky AM,. Transcriptional regulation of RANTES expression in T lymphocytes. Immunol Rev 2000; 177: 236-245.
    • (2000) Immunol Rev , vol.177 , pp. 236-245
    • Song, A.1    Nikolcheva, T.2    Krensky, A.M.3
  • 47
    • 35748974543 scopus 로고    scopus 로고
    • Immunological effects of silica and asbestos
    • Otsuki T, Maeda M, Murakami S, et al., Immunological effects of silica and asbestos. Cell Mol Immunol 2007; 4: 261-268.
    • (2007) Cell Mol Immunol , vol.4 , pp. 261-268
    • Otsuki, T.1    Maeda, M.2    Murakami, S.3
  • 48
    • 0020681656 scopus 로고
    • Asbestos exposure correlates with alterations in circulating T cell subsets
    • Miller LG, Sparrow D, Ginns LC,. Asbestos exposure correlates with alterations in circulating T cell subsets. Clin Exp Immunol 1983; 51: 110-116.
    • (1983) Clin Exp Immunol , vol.51 , pp. 110-116
    • Miller, L.G.1    Sparrow, D.2    Ginns, L.C.3
  • 49
    • 77749280258 scopus 로고    scopus 로고
    • Variability of CD3 membrane expression and T cell activation capacity
    • El
    • El, Hentati FZ, Gruy F, Iobagiu C, et al., Variability of CD3 membrane expression and T cell activation capacity. Cytom B Clin Cytom 2010; 78: 105-114.
    • (2010) Cytom B Clin Cytom , vol.78 , pp. 105-114
    • Hentati, F.Z.1    Gruy, F.2    Iobagiu, C.3
  • 50
    • 34848839897 scopus 로고    scopus 로고
    • Modulation of CD4 co-receptor limits spontaneous autoimmunity when high-affinity transgenic TCR specific for self-antigen is expressed on a genetically resistant background
    • Illes Z, Waldner H, Reddy J, et al., Modulation of CD4 co-receptor limits spontaneous autoimmunity when high-affinity transgenic TCR specific for self-antigen is expressed on a genetically resistant background. Int Immunol 2007; 19: 1235-1248.
    • (2007) Int Immunol , vol.19 , pp. 1235-1248
    • Illes, Z.1    Waldner, H.2    Reddy, J.3
  • 51
    • 33750518197 scopus 로고    scopus 로고
    • The uncoupling protein 2 modulates the cytokine balance in innate immunity
    • Rousset S, Emre Y, Join-Lambert O, et al., The uncoupling protein 2 modulates the cytokine balance in innate immunity. Cytokine 2006; 35: 135-142.
    • (2006) Cytokine , vol.35 , pp. 135-142
    • Rousset, S.1    Emre, Y.2    Join-Lambert, O.3
  • 52
    • 77951274305 scopus 로고    scopus 로고
    • Uncoupling protein UCP2: When mitochondrial activity meets immunity
    • Emre Y, Nubel T,. Uncoupling protein UCP2: when mitochondrial activity meets immunity. FEBS Lett 2010; 584: 1437-1442.
    • (2010) FEBS Lett , vol.584 , pp. 1437-1442
    • Emre, Y.1    Nubel, T.2
  • 53
    • 0242663915 scopus 로고    scopus 로고
    • 2+- and redox-dependent production of nitric oxide
    • 2+- and redox-dependent production of nitric oxide. J Immunol 2003; 171: 5188-5197.
    • (2003) J Immunol , vol.171 , pp. 5188-5197
    • Nagy, G.1    Koncz, A.2    Perl, A.3
  • 54
    • 0037100275 scopus 로고    scopus 로고
    • Persistent mitochondrial hyperpolarization, increased reactive oxygen intermediate production, and cytoplasmic alkalinization characterize altered IL-10 signaling in patients with systemic lupus erythematosus
    • Gergely P Jr, Niland B, Gonchoroff N, et al., Persistent mitochondrial hyperpolarization, increased reactive oxygen intermediate production, and cytoplasmic alkalinization characterize altered IL-10 signaling in patients with systemic lupus erythematosus. J Immunol 2002; 169: 1092-1101.
    • (2002) J Immunol , vol.169 , pp. 1092-1101
    • Gergely, Jr.P.1    Niland, B.2    Gonchoroff, N.3
  • 55
    • 79851495475 scopus 로고    scopus 로고
    • Frequent absence of tumor suppressor FUS1 protein expression in human bone and soft tissue sarcomas
    • Li G, Kawashima H, Ji L, et al., Frequent absence of tumor suppressor FUS1 protein expression in human bone and soft tissue sarcomas. Anticancer Res 2011; 31: 11-21.
    • (2011) Anticancer Res , vol.31 , pp. 11-21
    • Li, G.1    Kawashima, H.2    Ji, L.3
  • 56
    • 0034327412 scopus 로고    scopus 로고
    • The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: Identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium
    • Lerman MI, Minna JD,. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium. Cancer Res 2000; 60: 6116-6133.
    • (2000) Cancer Res , vol.60 , pp. 6116-6133
    • Lerman, M.I.1    Minna, J.D.2
  • 57
    • 53849116091 scopus 로고    scopus 로고
    • Role of IL-10 in the resolution of airway inflammation
    • Ogawa Y, Duru EA, Ameredes BT,. Role of IL-10 in the resolution of airway inflammation. Curr Mol Med 2008; 8: 437-445.
    • (2008) Curr Mol Med , vol.8 , pp. 437-445
    • Ogawa, Y.1    Duru, E.A.2    Ameredes, B.T.3
  • 58
    • 33746787729 scopus 로고    scopus 로고
    • RANTES (CCL5) regulates airway responsiveness after repeated allergen challenge
    • Koya T, Takeda K, Kodama T, et al., RANTES (CCL5) regulates airway responsiveness after repeated allergen challenge. Am J Respir Cell Mol Biol 2006; 35: 147-154.
    • (2006) Am J Respir Cell Mol Biol , vol.35 , pp. 147-154
    • Koya, T.1    Takeda, K.2    Kodama, T.3
  • 60
    • 65249143925 scopus 로고    scopus 로고
    • Protumorigenic role of HAPLN1 and its IgV domain in malignant pleural mesothelioma
    • Ivanova AV, Goparaju CM, Ivanov SV, et al., Protumorigenic role of HAPLN1 and its IgV domain in malignant pleural mesothelioma. Clin Cancer Res 2009; 15: 2602-2611.
    • (2009) Clin Cancer Res , vol.15 , pp. 2602-2611
    • Ivanova, A.V.1    Goparaju, C.M.2    Ivanov, S.V.3
  • 61
    • 77951109790 scopus 로고    scopus 로고
    • CCL5 as an adjuvant for cancer immunotherapy
    • Lapteva N, Huang XF,. CCL5 as an adjuvant for cancer immunotherapy. Expert Opin Biol Ther 2010; 10: 725-733.
    • (2010) Expert Opin Biol Ther , vol.10 , pp. 725-733
    • Lapteva, N.1    Huang, X.F.2
  • 62
    • 33644841500 scopus 로고    scopus 로고
    • The role and mechanisms of double negative regulatory T cells in the suppression of immune responses
    • Chen W, Ford MS, Young KJ, et al., The role and mechanisms of double negative regulatory T cells in the suppression of immune responses. Cell Mol Immunol 2004; 1: 328-335.
    • (2004) Cell Mol Immunol , vol.1 , pp. 328-335
    • Chen, W.1    Ford, M.S.2    Young, K.J.3
  • 63
    • 33749607355 scopus 로고    scopus 로고
    • Double-negative regulatory T cells: Non-conventional regulators
    • Thomson CW, Lee BP, Zhang L,. Double-negative regulatory T cells: non-conventional regulators. Immunol Res 2006; 35: 163-178.
    • (2006) Immunol Res , vol.35 , pp. 163-178
    • Thomson, C.W.1    Lee, B.P.2    Zhang, L.3
  • 64
    • 33847048512 scopus 로고    scopus 로고
    • - double-negative T cells in peripheral blood of children with Behcet's disease
    • - double-negative T cells in peripheral blood of children with Behcet's disease. Autoimmun Rev 2007; 6: 237-240.
    • (2007) Autoimmun Rev , vol.6 , pp. 237-240
    • Ling, E.1    Shubinsky, G.2    Press, J.3
  • 65
    • 34547857758 scopus 로고    scopus 로고
    • Peptide-activated double-negative T cells can prevent autoimmune type-1 diabetes development
    • Ford MS, Chen W, Wong S, et al., Peptide-activated double-negative T cells can prevent autoimmune type-1 diabetes development. Eur J Immunol 2007; 37: 2234-2241.
    • (2007) Eur J Immunol , vol.37 , pp. 2234-2241
    • Ford, M.S.1    Chen, W.2    Wong, S.3
  • 66
    • 0034327735 scopus 로고    scopus 로고
    • Human double-negative T cells in systemic lupus erythematosus provide help for IgG and are restricted by CD1c
    • Sieling PA, Porcelli SA, Duong BT, et al., Human double-negative T cells in systemic lupus erythematosus provide help for IgG and are restricted by CD1c. J Immunol 2000; 165: 5338-5344.
    • (2000) J Immunol , vol.165 , pp. 5338-5344
    • Sieling, P.A.1    Porcelli, S.A.2    Duong, B.T.3
  • 67
    • 58849162766 scopus 로고    scopus 로고
    • Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys
    • Crispin JC, Oukka M, Bayliss G, et al., Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys. J Immunol 2008; 181: 8761-8766.
    • (2008) J Immunol , vol.181 , pp. 8761-8766
    • Crispin, J.C.1    Oukka, M.2    Bayliss, G.3
  • 68
    • 0034876118 scopus 로고    scopus 로고
    • - T cells in humans with the autoimmune lymphoproliferative syndrome express a novel CD45 isoform that is analogous to murine B220 and represents a marker of altered O-glycan biosynthesis
    • - T cells in humans with the autoimmune lymphoproliferative syndrome express a novel CD45 isoform that is analogous to murine B220 and represents a marker of altered O-glycan biosynthesis. Clin Immunol 2001; 100: 314-324.
    • (2001) Clin Immunol , vol.100 , pp. 314-324
    • Bleesing, J.J.1    Brown, M.R.2    Dale, J.K.3
  • 69
    • 0038545422 scopus 로고    scopus 로고
    • Inhibition of graft-versus-host disease by double-negative regulatory T cells
    • Young KJ, DuTemple B, Phillips MJ, et al., Inhibition of graft-versus-host disease by double-negative regulatory T cells. J Immunol 2003; 171: 134-141.
    • (2003) J Immunol , vol.171 , pp. 134-141
    • Young, K.J.1    Dutemple, B.2    Phillips, M.J.3
  • 71
    • 0030743779 scopus 로고    scopus 로고
    • - T cells differentiate extrathymically in an lck-independent manner and participate in early response against Listeria monocytogenes infection through interferon-γ production
    • - T cells differentiate extrathymically in an lck-independent manner and participate in early response against Listeria monocytogenes infection through interferon-γ production. Immunology 1997; 91: 511-519.
    • (1997) Immunology , vol.91 , pp. 511-519
    • Kadena, T.1    Matsuzaki, G.2    Fujise, S.3
  • 72
    • 34249826035 scopus 로고    scopus 로고
    • - T cells and cytokine serum levels in young and adult rats
    • - T cells and cytokine serum levels in young and adult rats. Exp Parasitol 2007; 116: 366-374.
    • (2007) Exp Parasitol , vol.116 , pp. 366-374
    • Nagib, P.R.1    Dutra, W.O.2    Chiari, E.3
  • 73
    • 70449719356 scopus 로고    scopus 로고
    • + T cells and display an inflammatory effector phenotype
    • + T cells and display an inflammatory effector phenotype. J Immunol 2009; 183: 4675-4681.
    • (2009) J Immunol , vol.183 , pp. 4675-4681
    • Crispin, J.C.1    Tsokos, G.C.2
  • 78
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov SI, Greten FR, Karin M,. Immunity, inflammation, and cancer. Cell 2010; 140: 883-899.
    • (2010) Cell , vol.140 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 79
    • 33746599842 scopus 로고    scopus 로고
    • Regulatory T cells in cancer
    • Beyer M, Schultze JL,. Regulatory T cells in cancer. Blood 2006; 108: 804-811.
    • (2006) Blood , vol.108 , pp. 804-811
    • Beyer, M.1    Schultze, J.L.2
  • 80
    • 70349637849 scopus 로고    scopus 로고
    • Stanniocalcin-1 suppresses superoxide generation in macrophages through induction of mitochondrial UCP2
    • Wang Y, Huang L, Abdelrahim M, et al., Stanniocalcin-1 suppresses superoxide generation in macrophages through induction of mitochondrial UCP2. J Leukoc Biol 2009; 86: 981-988.
    • (2009) J Leukoc Biol , vol.86 , pp. 981-988
    • Wang, Y.1    Huang, L.2    Abdelrahim, M.3
  • 81
    • 79251500689 scopus 로고    scopus 로고
    • Manipulating the bioenergetics of alloreactive T cells causes their selective apoptosis and arrests graft-versus-host disease
    • Gatza E, Wahl DR, Opipari AW, et al., Manipulating the bioenergetics of alloreactive T cells causes their selective apoptosis and arrests graft-versus-host disease. Sci Transl Med 2011; 3: 67ra68.
    • (2011) Sci Transl Med , vol.3
    • Gatza, E.1    Wahl, D.R.2    Opipari, A.W.3
  • 83
    • 77955483825 scopus 로고    scopus 로고
    • Up-regulation of the ATPase inhibitory factor 1 (IF1) of the mitochondrial H + -ATP synthase in human tumors mediates the metabolic shift of cancer cells to a Warburg phenotype
    • Sanchez-Cenizo L, Formentini L, Aldea M, et al., Up-regulation of the ATPase inhibitory factor 1 (IF1) of the mitochondrial H + -ATP synthase in human tumors mediates the metabolic shift of cancer cells to a Warburg phenotype. J Biol Chem 2010; 285: 25308-25313.
    • (2010) J Biol Chem , vol.285 , pp. 25308-25313
    • Sanchez-Cenizo, L.1    Formentini, L.2    Aldea, M.3
  • 84
    • 0025163754 scopus 로고
    • Cytotoxicity of long and short crocidolite asbestos fibers in vitro and in vivo
    • Goodglick LA, Kane AB,. Cytotoxicity of long and short crocidolite asbestos fibers in vitro and in vivo. Cancer Res 1990; 50: 5153-5163.
    • (1990) Cancer Res , vol.50 , pp. 5153-5163
    • Goodglick, L.A.1    Kane, A.B.2
  • 85
    • 4243403960 scopus 로고    scopus 로고
    • Asbestos-induced alveolar epithelial cell apoptosis: Role of mitochondrial dysfunction caused by iron-derived free radicals
    • Kamp DW, Panduri V, Weitzman SA, et al., Asbestos-induced alveolar epithelial cell apoptosis: role of mitochondrial dysfunction caused by iron-derived free radicals. Mol Cell Biochem 2002; 234-235: 153-160.
    • (2002) Mol Cell Biochem , vol.234-235 , pp. 153-160
    • Kamp, D.W.1    Panduri, V.2    Weitzman, S.A.3
  • 86
    • 0037308538 scopus 로고    scopus 로고
    • The mitochondria-regulated death pathway mediates asbestos-induced alveolar epithelial cell apoptosis
    • Panduri V, Weitzman SA, Chandel N, et al., The mitochondria-regulated death pathway mediates asbestos-induced alveolar epithelial cell apoptosis. Am J Respir Cell Mol Biol 2003; 28: 241-248.
    • (2003) Am J Respir Cell Mol Biol , vol.28 , pp. 241-248
    • Panduri, V.1    Weitzman, S.A.2    Chandel, N.3
  • 87
    • 0033667705 scopus 로고    scopus 로고
    • Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production
    • Arsenijevic D, Onuma H, Pecqueur C, et al., Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production. Nat Genet 2000; 26: 435-439.
    • (2000) Nat Genet , vol.26 , pp. 435-439
    • Arsenijevic, D.1    Onuma, H.2    Pecqueur, C.3
  • 89
    • 77953384917 scopus 로고    scopus 로고
    • Redox regulation in cancer: A double-edged sword with therapeutic potential
    • Acharya A, Das I, Chandhok D, et al., Redox regulation in cancer: a double-edged sword with therapeutic potential. Oxid Med Cell Longev 2010; 3: 23-34.
    • (2010) Oxid Med Cell Longev , vol.3 , pp. 23-34
    • Acharya, A.1    Das, I.2    Chandhok, D.3
  • 90
    • 77955274524 scopus 로고    scopus 로고
    • Redox metabolism and malignancy
    • Grek CL, Tew KD,. Redox metabolism and malignancy. Curr Opin Pharmacol 2010; 10: 362-368.
    • (2010) Curr Opin Pharmacol , vol.10 , pp. 362-368
    • Grek, C.L.1    Tew, K.D.2
  • 91
    • 77954562833 scopus 로고    scopus 로고
    • Metastasis: Cancer cells' escape from oxidative stress
    • Pani G, Galeotti T, Chiarugi P,. Metastasis: cancer cells' escape from oxidative stress. Cancer Metast Rev 2010; 29: 351-378.
    • (2010) Cancer Metast Rev , vol.29 , pp. 351-378
    • Pani, G.1    Galeotti, T.2    Chiarugi, P.3
  • 92
    • 33645841353 scopus 로고    scopus 로고
    • Biphasic effects of dietary antioxidants on oxidative stress-mediated carcinogenesis
    • Lee KW, Lee HJ,. Biphasic effects of dietary antioxidants on oxidative stress-mediated carcinogenesis. Mech Ageing Dev 2006; 127: 424-431.
    • (2006) Mech Ageing Dev , vol.127 , pp. 424-431
    • Lee, K.W.1    Lee, H.J.2
  • 93
    • 34548840599 scopus 로고    scopus 로고
    • Genotoxicity of poorly soluble particles
    • Schins RP, Knaapen AM,. Genotoxicity of poorly soluble particles. Inhal Toxicol 2007; 19 (suppl 1): 189-198.
    • (2007) Inhal Toxicol , vol.19 , Issue.SUPPL. 1 , pp. 189-198
    • Schins, R.P.1    Knaapen, A.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.