Overexpression of candidate tumor suppressor gene FUS1 isolated from the 3p21.3 homozygous deletion region leads to G1 arrest and growth inhibition of lung cancer cells

Oncogene

Volumn 20, Issue 43, 2001, Pages 6258-6262

  Kondo, Masashi ^a   Ji, Lin ^b   Kamibayashi, Craig ^a   Tomizawa, Yoshio ^a   Randle, Dwight ^a   Sekido, Yoshitaka ^c   Yokota, Jun ^d   Kashuba, Vladimir ^e   Zabarovsky, Eugene ^e   Kuzmin, Igor ^f   Lerman, Michael ^f   Roth, Jack ^b   Minna, John D ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^e KAROLINSKA INSTITUTE   (Sweden)

^f NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Growth inhibition; Lung cancer; Tumor suppressor gene

Indexed keywords

GENE PRODUCT; MUTANT PROTEIN; PROTEIN FUS1; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE G1 PHASE; COLONY FORMATION; CONTROLLED STUDY; GENE DELETION; GENE FUNCTION; GENE ISOLATION; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LUNG CANCER; LUNG CARCINOGENESIS; LUNG NON SMALL CELL CANCER; METHYLATION; PRIORITY JOURNAL; PROMOTER REGION; TUMOR SUPPRESSOR GENE;

ALLELES; BLOTTING, WESTERN; CELL DIVISION; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 3; DNA METHYLATION; FUNGAL PROTEINS; HOMOZYGOTE; HUMANS; LUNG NEOPLASMS; MODELS, GENETIC; MUTATION; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0035959880     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1204832     Document Type: Article

References (21)