Novel interactions between NFATc1 (nuclear factor of activated T cells c1) and STAT-3 (signal transducer and activator of transcription-3) mediate G protein-coupled receptor agonist, thrombin-induced biphasic expression of cyclin D1, with first phase influencing cell migration and second phase directing cell proliferation

Journal of Biological Chemistry

Volumn 287, Issue 27, 2012, Pages 22463-22482

  Kundumani Sridharan, Venkatesh ^a   Van Quyen, Dong ^a   Subramani, Jaganathan ^a   Singh, Nikhlesh K ^a   Chin, Y Eugene ^b   Rao, Gadiparthi N ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MIGRATION; COMPLEX BINDING; COOPERATIVE INTERACTIONS; CYCLIND1; DUAL FUNCTION; G PROTEIN COUPLED RECEPTORS; NUCLEAR FACTOR OF ACTIVATED T-CELLS; OVER-EXPRESSION; REPORTER GENE ASSAYS; SECOND PHASE; SIGNAL TRANSDUCERS; VASCULAR SMOOTH MUSCLE CELLS;

AMINO ACIDS; CELL PROLIFERATION; CYTOLOGY; ENZYMES; GENES; PHOSPHORYLATION; TRANSCRIPTION;

ACETYLATION;

CYCLIN D1; ENHANCEOSOME; PROTEIN P300; STAT3 PROTEIN; THROMBIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NFATC1; TYROSINE; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; CELL MIGRATION; CELL NUCLEUS; CELL PROLIFERATION; CELL TRANSPORT; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOPLASM; GEL MOBILITY SHIFT ASSAY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; REPORTER GENE; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ACETYLATION; ANIMALS; BASE SEQUENCE; CELL DIVISION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN D1; GENE EXPRESSION REGULATION; MALE; MOLECULAR SEQUENCE DATA; MUSCLE, SMOOTH, VASCULAR; NFATC TRANSCRIPTION FACTORS; PROMOTER REGIONS, GENETIC; RATS; RECEPTORS, G-PROTEIN-COUPLED; STAT3 TRANSCRIPTION FACTOR; THROMBIN;

EID: 84863308707     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.362996     Document Type: Article

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