ICA512 signaling enhances pancreatic β-cell proliferation by regulating cyclins D through STATs

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 2, 2008, Pages 674-679

  Mziaut, Hassan ^a   Kersting, Stephan ^a   Knoch, Klaus Peter ^a   Fan, Wan Hung ^a   Trajkovski, Mirko ^a   Erdmann, Katja ^a   Bergert, Hendrik ^a   Ehehalt, Florian ^a   Saeger, Hans Detlev ^a   Solimena, Michele ^a,b  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

Author keywords

Diabetes; Insulin; Phosphatase; Regeneration; Secretion

Indexed keywords

AUTOANTIGEN; CYCLIN D; CYCLIN D1; CYCLIN D2; INSULIN; ISLET CELL AUTOANTIGEN 512; STAT PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BIOGENESIS; CELL PROLIFERATION; CELL REGENERATION; CONTROLLED STUDY; EXOCYTOSIS; GENETIC TRANSCRIPTION; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; UPREGULATION;

ANIMALS; CELL PROLIFERATION; CYCLINS; DIABETES MELLITUS; GENE EXPRESSION REGULATION; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MODELS, BIOLOGICAL; PHOSPHORYLATION; RATS; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 8; REGENERATION; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; STAT5 TRANSCRIPTION FACTOR;

MUS;

EID: 38649136568     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0710931105     Document Type: Article

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