The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR

Nature Immunology

Volumn 10, Issue 7, 2009, Pages 769-777

  Liu, Guangwei ^a   Burns, Samir ^a   Huang, Gonghua ^a   Boyd, Kelli ^a   Proia, Richard L ^b   Flavell, Richard A ^c   Chi, Hongbo ^a,c  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (4 HYDROXYPHENYL) 4 MORPHOLINOPYRIDO[3',2':4,5]FURO[3,2 D]PYRIMIDINE; 2 MORPHOLINO 8 PHENYLCHROMONE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; GREEN FLUORESCENT PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE INHIBITOR; RAG1 PROTEIN; RAPAMYCIN; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 1; STAT5 PROTEIN; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; CARRIER PROTEIN; CD45 ANTIGEN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; FRAP1 PROTEIN, MOUSE; INTERLEUKIN 2 RECEPTOR ALPHA; PHOSPHOTRANSFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOIMMUNITY; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL COMPARTMENTALIZATION; CELL MATURATION; CELLULAR DISTRIBUTION; COLITIS; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; GENE FUNCTION; HOMEOSTASIS; HUMAN; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTE DIFFERENTIATION; NONHUMAN; PRE T LYMPHOCYTE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; THYMUS; ADOPTIVE TRANSFER; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; COLON; CYTOLOGY; FLOW CYTOMETRY; GENETICS; IMMUNOLOGY; MALE; METABOLISM; MOUSE; MOUSE MUTANT; NEWBORN; PATHOLOGY; TRANSGENIC MOUSE; TRANSPLANTATION;

ADOPTIVE TRANSFER; ANIMALS; ANIMALS, NEWBORN; ANTIGENS, CD45; CARRIER PROTEINS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; COLON; FEMALE; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; HOMEOSTASIS; IMMUNE TOLERANCE; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, LYSOSPHINGOLIPID; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; THYMUS GLAND;

EID: 67649185215     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.1743     Document Type: Article

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