Mitochondrial dysfunction and transactivation of p53-dependent apoptotic genes in BaP-treated human fetal lung fibroblasts

Human and Experimental Toxicology

Volumn 30, Issue 12, 2011, Pages 1904-1913

  Yang, Guangtao ^a   Jiang, Ying ^a   Rao, Kaimin ^a   Chen, Xi ^a   Wang, Qian ^a   Liu, Ailin ^a   Xiong, Wei ^a   Yuan, Jing ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Benzo(a)pyrene; Human fetal lung fibroblasts (MRC 5) cells; Mitochondrial dysfunction; Oxidative stress

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; BENZO[A]PYRENE; CASPASE 3; CASPASE 9; CYTOCHROME C; MESSENGER RNA; PROTEIN NOXA; PROTEIN P53; PUMA PROTEIN; REACTIVE OXYGEN METABOLITE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL MEMBRANE DEPOLARIZATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG FIBROBLAST; MEMBRANE POTENTIAL; MITOCHONDRIAL DNA DISORDER; PRIORITY JOURNAL; PROTEIN EXPRESSION; TOXICITY TESTING; TRANSACTIVATION; TRANSCRIPTION REGULATION;

APOPTOSIS; BENZO(A)PYRENE; CARCINOGENS; CELL LINE; CELL SURVIVAL; CYTOCHROMES C; FETUS; FIBROBLASTS; GENE EXPRESSION; HUMANS; LUNG; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL DISEASES; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RIBOSOMAL PROTEINS; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84863070611     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327111401637     Document Type: Article

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