Gaseous nitrogen oxide repressed benzo[a]pyrene-induced human lung fibroblast cell apoptosis via inhibiting JNK1 signals

Archives of Toxicology

Volumn 79, Issue 12, 2005, Pages 694-704

  Chen, Jing Hsien ^a   Chou, Fen Pi ^a   Lin, Hui Hsuan ^a   Wang, Chau Jong ^a  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Anti apoptosis; Benzo a pyrene (B a P); Gaseous nitrogen oxide; JNK1

Indexed keywords

BENZO[A]PYRENE; CYTOCHROME C; FAS LIGAND; FREE RADICAL; NITROGEN OXIDE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MCL 1; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE 1;

AIR POLLUTANT; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CELL CYCLE; CELL PROLIFERATION; HEPATOMA CELL; HUMAN; HUMAN CELL; INDOOR AIR POLLUTION; LUNG FIBROBLAST; LUNG PARENCHYMA; MACROPHAGE; POLLUTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ANTIGENS, CD95; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BENZO(A)PYRENE; CARCINOGENS; CELL CYCLE; CELLS, CULTURED; FAS LIGAND PROTEIN; FIBROBLASTS; HUMANS; LUNG; MEMBRANE GLYCOPROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 8; NITRIC OXIDE; RECEPTORS, TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 28544437773     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-005-0001-0     Document Type: Article

References (52)

1. Adler V, Pincus MR, Minamoto T, Fuchs SY, Bluth MJ, W, B-RP, Friedman FK, Robinson RC, Chen JM, Wang XW, Harris CC, Ronai Z (1997) Conformation-dependent phosphorylation of p53. Proc Natl Acad Sci USA 94:1686-1691
2. Angerer J, Mannschreck C, Gundel J (1997) Biological monitoring and biochemical effect monitoring of exposure to polycyclic aromatic hydrocarbons. Int Arch Occup Environ Health 70:365-377
3. Chang WC, Lee YC, Liu CL, Hsu JD, Wang HC, Chen CC, Wang CJ (2001) Increased expression of iNOS and c-fos via regulation of protein tyrosine phosphorylation and MEK1/ERK2 proteins in terminal bronchiole lesions in the lungs of rats exposed to cigarette smoke. Arch Toxicol 75:28-35
4. Chan-Hui PY, Weaver R (1998) Human mitogen-activated protein kinase kinase kinase mediates the stress-induced activation of mitogen-activated protein kinase cascades. Biochem J 336:599-609
5. Chen Y, Lai MZ (2001) c-Jun NH2-terminal kinase activation leads to a FADD-dependent but Fas ligand-independent cell death in Jurkat T cells. J Biol Chem 276:8350-8357
6. Chen YR, Wang X, Templeton D, Davis RJ, Tan TH (1996) The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation duration of JNK activation may determine cell death and proliferation. J Biol Chem 271:31929-31936
7. Chen Z, Seimiya H, Naito M, Mashima T, Kizaki A, Dan S, Imaizumi M, Ichijo H, Miyazono K, Tsuruo T (1999) ASK1 mediates apoptotic cell death induced by genotoxic stress. Oncogene 18:173-180
8. Chen JH, Tseng TH, Ho YC, Lin HH, Lin WL, Wang CJ (2003) Gaseous nitrogen oxides stimulate cell cycle progression by retinoblastoma phosphorylation via activation of cyclins/Cdks. Toxicol Sci 76:83-90
9. Chen J, Yan Y, Li J, Ma Q, Stoner GD, Ye J, Huang C (2005) Differential requirement of signal pathways for benzo[a]pyrene (B[a]P)-induced nitric oxide synthase (iNOS) in rat esophageal epithelial cells. Carcinogenesis 26:1035-1043
10. Chin BY, Choi ME, Burdick MD, Strieter RM, Risby TH, Choi AM (1998) Induction of apoptosis by particulate matter: role of TNF-alpha and MAPK. Am J Physiol 275:L942-L949
11. Chipuk JE, Kuwana T, Bouchier-Hayes L, Droin NM, Newmeyer DD, Schuler M, Green DR (2004) Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 303:1010-1014
12. Cobb MH, Goldsmith EJ (1995) How MAP kinases are regulated. J Biol Chem 270:14843-14846
13. Drew B, Leeuwenburgh C (2002) Aging and the role of reactive nitrogen species. Ann N Y Acad Sci 959:66-81
14. Fuchs S, Adler V, Pincus MR, Ronai Z (1998) MEKK1/JNK signaling stabilizes and activates p53. Proc Natl Acad Sci USA 95:10541-10546
15. Gibson EM, Henson ES, Villanueva J, Gibson SB (2002) MEK kinase 1 induces mitochondrial permeability transition leading to apoptosis independent of cytochrome c release. J Biol Chem 277:10573-10580
16. Gosset P, Garcon G, Casset A, Fleurisse L, Hannothiaux MH, Creusy C, Shirali P (2003) Benzo(a)pyrene-coated onto Fe(2)O(3) particles-induced apoptotic events in the lungs of Sprague-Dawley rats. Toxicol Lett 143:223-232
17. Herr I, Debatin KM (2001) Cellular stress response and apoptosis in cancer therapy. Blood 98:2603-2614
18. Hollstein M, McCann J, Angelosanto FA, Nichols WW (1979) Short-term tests for carcinogens and mutagens. Mutat Res 65:133-226
19. Hoyt JC, Robbins RA, Habib M, Springall DR, Buttery LD, Polak JM, Barnes PJ (2003) Cigarette smoke decreases inducible nitric oxide synthase in lung epithelial cells. Exp Lung Res 29:17-28
20. Hsieh YS, Wang HC, Tseng TW, Chang WC, Wang CJ (2001) Gaseous nitric oxide-induced 8-nitroguanine formation in human lung fibroblast cells and cell-free DNA. Toxicol Appl Pharmacol 172:210-216
21. Huberman E, Sachs L, Yang SK, Gelboin V (1976) Identification of mutagenic metabolites of benzo(a)pyrene in mammalian cells. Proc Natl Acad Sci USA 73:607-611
22. Hunter T, Pines J (1994) Cyclins and cancer II: Cyclin D and CDK inhibitors come of age. Cell 79:573-582
23. Kim YM, Bergonia H, Lancaster JR (1995) Nitrogen oxide-induced autoprotection in isolated rat hepatocytes. FEBS Lett 374:228-232
24. Kim YM, de Vera ME, Watkins SC, Billiar TR (1997) Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-alpha-induced apoptosis by inducing heat shock protein 70 expression. J Biol Chem 272:1402-1411
25. Kim YM, Talanian RV, Billiar TR (1997) Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms. J Biol Chem 272:31138-31148
26. Kim YM, Chung HT, Kim SS, Han JA, Yoo YM, Kim KM, Lee GH, Yun HY, Green A, Li J, Simmons RL, Billiar TR (1999) Nitric oxide protects PC 12 cells from serum deprivation-induced apoptosis by cGMP-dependent inhibition of caspase signaling. J Neurosci 19:6740-6747
27. Kim YM, Chung HT, Simmons RL, Billiar TR (2000) Cellular non-heme iron content is a determinant of nitric oxide-mediated apoptosis, necrosis, caspase inhibition. J Biol Chem 275:10954-10961
28. Kuwano K, Miyazaki H, Hagimoto N, Kawasaki M, Fujita M, Kunitake R, Kaneko Y, Hara N (1999) The involvement of Fas-Fas ligand pathway in fibrosing lung diseases. Am J Respir Cell Mol Biol 20:53-60
29. Kwan R, Burnside J, Kurosaki T, Cheng G (2001) MEKK1 is essential for DT40 cell apoptosis in response to microtubule disruption. Mol Cell Biol 21:7183-7190
30. Kwon YG, Min JK, Kim KM, Lee DJ, Billiar TR, Kim YM (2000) Sphingosine 1-phosphate protects human umbilical vein endothelial cells from serum-deprived apoptosis by nitric oxide production. J Biol Chem 276:10627-10633
31. Leaderer B (1982) Air pollutant emixxions from kerosene space heater. Science 218:1113-1116
32. Lei W, Yu R, Mandlekar S, Kong AN (1998) Induction of apoptosis and activation of interleukin 1beta-converting enzyme/ Ced-3 protease (caspase-3) and c-Jun NH2-terminal kinase 1 by benzo(a)pyrene. Cancer Res 58:2102-2106
33. Li H, Zhu H, Xu CJ, Yuan J (1998) Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 94:491-501
34. Luo X, Budihardjo I, Zou H, Slaughter C, Wang X (1998) Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94:481-490
35. Maruyama J, Jiang BH, Maruyama K, Takata M, Miyasaka K (2004) Prolonged nitric oxide inhalation during recovery from chronic hypoxia does not decrease nitric oxide-dependent relaxation in pulmonary arteries. Chest 126:1919-1925
36. Mihara M, Erster S, Zaika A, Petrenko O, Chittenden T, Pancoska P, Moll UM (2003) p53 has a direct apoptogenic role at the mitochondria. Mol Cell 11:577-590
37. Milne DM, Campbell LE, Campbell DG, Meek DW (1995) p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1. J Biol Chem 270:5511-5518
38. Ou J, Carlos TM, Watkins SC, Saavedra JE, Keefer LK, Kim YM, Harbrecht BG, Billiar TR (1997) Differential effects of nonselective nitric oxide synthase (NOS) and selective inducible NOS inhibition on hepatic necrosis, apoptosis, ICAM-1 expression, and neutrophil accumulation during endotoxemia. Nitric Oxide 1:404-416
39. Petruzzelli S, Celi A, Pulera N, Baliva F, Viegi G, Carrozzi L, Ciacchini G, Bottai M, Di Pede F, Paoletti P, Giuntini C (1998) Serum antibodies to benzo(a)pyrene diol epoxide-DNA adducts in the general population: effects of air pollution, tobacco smoking, and family history of lung diseases. Cancer Res 58:4122-4126
40. Pitot HC, Dragan YP (1996) Chemical carcinogenesis. In: Klassen CD (ed) Casarett and Doull's toxicology. McGraw-Hill Book Co, New York, pp 201-267
41. Radi R, Cassina A, Hodara R (2002) Nitric oxide and peroxynitrite interactions with mitochondria. Biol Chem 383:401-409
42. Romanska HM, Ikonen TS, Bishop AE, Morris RE, Polak JM (2000) Up-regulation of inducible nitric oxide synthase in fibroblasts parallels the onset and progression of fibrosis in an experimental model of post-transplant obliterative airway disease. J Pathol 191:71-77
43. Rorke EA, Sizemore N, Mukhtar H, Couch LH, Howard PC (1998) Polycyclic aromatic hydrocarbons enhance terminal cell death of human ectocervical cells. Int J Oncol 13:557-563
44. Rowlands JC, Gustafsson JA (1997) Aryl hydrocarbon receptor-mediated signal transduction. Crit Rev Toxicol 27:109-134
45. Salas VM, Burchiel SW (1998) Apoptosis in Daudi human B cells in response to benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol. Toxicol Appl Pharmacol 151:367-376
46. Samet JM, Marbury MC, Spengler JD (1987) Health effects and sources of indoor air pollution, Part 1. Am Rev Respir Dis 136:1486-1508
47. Sánchez-Pérez I, Murguia JR, Perona R (1998) Cisplatin induces a persistent activation of JNK that is related to cell death. Oncogene 16:533-540
48. Soh JW, Mao Y, Liu L, Thompson WJ, Pamukcu R, Weinstein IB (2001) Protein kinase G activates the JNK1 pathway via phosphorylation of MEKK1. J Biol Chem 276:16406-16410
49. Tanaka T, Yoshimi M, Maeyama T, Hagimoto N, Kuwano K, Hara N (2002) Resistance to Fas-mediated apoptosis in human lung fibroblast. Eur Respir J 20:359-368
50. Vayssier-Taussat M, Camilli T, Aron Y, Meplan C, Hainaut P, Polla BS, Weksler B (2001) Effects of tobacco smoke and benzo[a]pyrene on human endothelial cell and monocyte stress responses. Am J Physiol Heart Circ Physiol 280:H1293-H1300
51. Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME (1995) Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270:1326-1331
52. Young L, Adamson IY (1993) Epithelial-fibroblast interactions in bleomycin-induced lung injury and repair. Environ Health Perspect 101:56-61