In vitro and in vivo studies on oxygen free radical and DNA adduct formation in rat lung and liver during benzo[a]pyrene metabolism

Free Radical Research

Volumn 38, Issue 9, 2004, Pages 995-1002

  Briedé, Jacob J ^a   Godschalk, Roger W L ^a   Emans, Marijn T G ^a   De Kok, Theo M C M ^a   Van Agen, Ebienus ^a   Van Maanen, Jan M S ^a   Van Schooten, Frederik Jan ^a   Kleinjans, Jos C S ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

8 Oxo dG; Benzo a pyrene; DNA damage; ESR; Reactive oxygen species

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; BENZO[A]PYRENE; CYTOCHROME P450; DNA; INDOMETACIN; ISOENZYME; OXYGEN RADICAL; PROADIFEN; PROSTAGLANDIN SYNTHASE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DNA REPAIR; ELECTRON SPIN RESONANCE; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME METABOLISM; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; LIVER MICROSOME; LIVER TOXICITY; LUNG TOXICITY; MALE; NONHUMAN; OXIDATION; RAT; TOXICITY TESTING; URINARY EXCRETION;

ANIMALS; BENZO(A)PYRENE; CELLS, CULTURED; DEOXYGUANOSINE; DNA ADDUCTS; DNA DAMAGE; ELECTRON SPIN RESONANCE SPECTROSCOPY; LIVER; LUNG; MALE; MICROSOMES, LIVER; RATS; RATS, INBRED LEW; REACTIVE OXYGEN SPECIES;

EID: 5044245540     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/10715760400000976     Document Type: Article

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