The role of aryl hydrocarbon receptor in regulation of enzymes involved in metabolic activation of polycyclic aromatic hydrocarbons in a model of rat liver progenitor cells

Chemico-Biological Interactions

Volumn 180, Issue 2, 2009, Pages 226-237

  Vondráček, Jan ^a,b   Krčmář, Pavel ^b   Procházková, Jiřina ^a,b   Trilecová, Lenka ^b   Gavelová, Martina ^c   Skálová, Lenka ^c   Szotáková, Barbora ^c   Bunček, Martin ^d   Radilová, Hana ^d   Kozubík, Alois ^a   Machala, Miroslav ^b  

^a INSTITUTE OF BIOPHYSICS   (Czech Republic)

^b VETERINARY RESEARCH INSTITUTE   (Czech Republic)

^c Charles University in Prague Faculty of Pharmacy   (Czech Republic)

^d GENERI BIOTECH sro   (Czech Republic)

Author keywords

AhR; Aldo keto reductases; Cytochromes P450; NQO1; NRF2; PAHs

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3ALPHA HYDROXYSTEROID DEHYDROGENASE; ALDEHYDE REDUCTASE; AROMATIC HYDROCARBON RECEPTOR; BENZO[A]PYRENE; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; HEME OXYGENASE 1; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ARTICLE; CARCINOGENICITY; CELL PROTECTION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME REGULATION; LIVER CELL; LIVER CELL CARCINOMA; METABOLIC ACTIVATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; STEM CELL; TOXICOKINETICS;

ANIMALS; BENZO(A)PYRENE; CELL LINE; DIMETHYL SULFOXIDE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE SILENCING; HYDROGEN PEROXIDE; LIVER; POLYCYCLIC HYDROCARBONS, AROMATIC; RATS; REACTIVE OXYGEN SPECIES; RECEPTORS, ARYL HYDROCARBON; STEM CELLS; TETRACHLORODIBENZODIOXIN;

RATTUS;

EID: 67349161804     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.03.011     Document Type: Article

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