Apoptotic Mitochondrial Dysfunction Induced by Benzo(a)pyrene in Liver Epithelial Cells: Role of p53 and pHi Changes

Annals of the New York Academy of Sciences

Volumn 1010, Issue , 2003, Pages 167-170

  Huc, Laurence ^a   Gilot, David ^a   Gardyn, Claire ^a   Rissel, Mary ^a   Dimanche Boitrel, Marie Thérèse ^a   Guillouzo, André ^a   Fardel, Olivier ^a   Lagadic Gossmann, Dominique ^a  

^a UNIVERSITÉ DE RENNES 1   (France)

Author keywords

Apoptosis; Benzo(a)pyrene; Intracellular pH; Mitochondria; p53; Rat liver epithelial cell; Reactive oxygen species

Indexed keywords

BENZO[A]PYRENE; CASPASE 3; PROTEIN P53;

ALKALINIZATION; ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; CELL PH; CONFERENCE PAPER; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EPITHELIUM CELL; LIVER CELL; LIVER MITOCHONDRION; LIVER TOXICITY; MITOCHONDRION; NONHUMAN; RAT;

ANIMALIA; RATTUS;

EID: 1342284298     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1299.028     Document Type: Conference Paper

References (5)

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3. FLEURY, C., B. MIGNOTTE & J.L. VAYSSIERE. 2002. Mitochondrial reactive oxygen species in cell death signaling. Biochimie 84: 131-141.
4. PERVAIZ, S. & M.-V. CLÉMENT. 2002. A permissive apoptotic environment: Function of a decrease in intracellular superoxide anion and cytosolic acidification. Biochem. Biophys. Res. Commun. 290: 1145-1150.
5. i changes in rat liver cells treated with benzo(a)pyrene. Pharmacologist 44(suppl. 1): A124 (abstract).