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Volumn 11, Issue 12, 2012, Pages 2337-2347

Timeless preserves telomere length by promoting efficient DNA replication through human telomeres

Author keywords

Replication efficiency; Telomere; Telomere aberration; The fork protection complex; Timeless; TRF1

Indexed keywords

PROTEIN TIMELESS; SHORT HAIRPIN RNA; TELOMERASE; TELOMERIC REPEAT BINDING FACTOR 1; TELOMERIC REPEAT BINDING FACTOR 2;

EID: 84862872436     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.20810     Document Type: Article
Times cited : (59)

References (75)
  • 1
    • 0015184804 scopus 로고
    • Principle of marginotomy in template synthesis of polynucleotides
    • PMID:5158754
    • Olovnikov AM. Principle of marginotomy in template synthesis of polynucleotides. Dokl Akad Nauk SSSR 1971; 201:1496-9; PMID:5158754.
    • (1971) Dokl Akad Nauk SSSR , vol.201 , pp. 1496-1499
    • Olovnikov, A.M.1
  • 2
    • 0015844590 scopus 로고
    • A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon
    • PMID:4754905
    • Olovnikov AM. A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon. J Theor Biol 1973; 41:181-90; PMID:4754905; http://dx.doi.org/ 10.1016/0022- 5193(73)90198-7.
    • (1973) J Theor Biol , vol.41 , pp. 181-190
    • Olovnikov, A.M.1
  • 3
    • 0015515155 scopus 로고
    • Origin of concatemeric T7 DNA
    • PMID:4507727
    • Watson JD. Origin of concatemeric T7 DNA. Nat New Biol 1972; 239:197-201; PMID:4507727.
    • (1972) Nat New Biol , vol.239 , pp. 197-201
    • Watson, J.D.1
  • 4
    • 0029162563 scopus 로고
    • Telomere elongation in immortal human cells without detectable telomerase activity
    • PMID:7556065
    • Bryan TM, Englezou A, Gupta J, Bacchetti S, Reddel RR. Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J 1995; 14:4240-8; PMID:7556065.
    • (1995) EMBO J , vol.14 , pp. 4240-4248
    • Bryan, T.M.1    Englezou, A.2    Gupta, J.3    Bacchetti, S.4    Reddel, R.R.5
  • 5
    • 0023663881 scopus 로고
    • The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity
    • PMID:3319189
    • Greider CW, Blackburn EH. The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity. Cell 1987; 51:887-98; PMID:3319189; http://dx.doi. org/10.1016/0092-8674(87) 90576-9.
    • (1987) Cell , vol.51 , pp. 887-898
    • Greider, C.W.1    Blackburn, E.H.2
  • 6
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
    • PMID:3907856
    • Greider CW, Blackburn EH. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 1985; 43:405-13; PMID:3907856; http://dx.doi.org/10.1016/0092-8674(85)90170-9.
    • (1985) Cell , vol.43 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 7
    • 24944460598 scopus 로고    scopus 로고
    • Shelterin: The protein complex that shapes and safeguards human telomeres
    • PMID:16166375
    • de Lange T. Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev 2005; 19:2100-10; PMID:16166375; http://dx.doi. org/10.1101/gad.1346005.
    • (2005) Genes Dev , vol.19 , pp. 2100-2110
    • De Lange, T.1
  • 8
    • 84984754548 scopus 로고    scopus 로고
    • Telomeric localization of TRF2, a novel human telobox protein
    • PMID:9326951
    • Bilaud T, Brun C, Ancelin K, Koering CE, Laroche T, Gilson E. Telomeric localization of TRF2, a novel human telobox protein. Nat Genet 1997; 17:236-9; PMID:9326951; http://dx.doi.org/10.1038/ng1097- 236.
    • (1997) Nat Genet , vol.17 , pp. 236-239
    • Bilaud, T.1    Brun, C.2    Ancelin, K.3    Koering, C.E.4    Laroche, T.5    Gilson, E.6
  • 9
    • 84984775429 scopus 로고    scopus 로고
    • Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2
    • PMID:9326950
    • Broccoli D, Smogorzewska A, Chong L, de Lange T. Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2. Nat Genet 1997; 17:231-5; PMID:9326950; http://dx.doi.org/10.1038/ng1097- 231.
    • (1997) Nat Genet , vol.17 , pp. 231-235
    • Broccoli, D.1    Smogorzewska, A.2    Chong, L.3    De Lange, T.4
  • 10
    • 0031027618 scopus 로고    scopus 로고
    • Control of telomere length by the human telomeric protein TRF1
    • PMID:9034193
    • van Steensel B, de Lange T. Control of telomere length by the human telomeric protein TRF1. Nature 1997; 385:740-3; PMID:9034193; http://dx.doi. org/10.1038/385740a0.
    • (1997) Nature , vol.385 , pp. 740-743
    • Van Steensel, B.1    De Lange, T.2
  • 11
    • 0035844082 scopus 로고    scopus 로고
    • Pot1, the putative telomere endbinding protein in fission yeast and humans
    • PMID:11349150
    • Baumann P, Cech TR. Pot1, the putative telomere endbinding protein in fission yeast and humans. Science 2001; 292:1171-5; PMID:11349150; http://dx.doi.org/10.1126/science.1060036.
    • (2001) Science , vol.292 , pp. 1171-1175
    • Baumann, P.1    Cech, T.R.2
  • 12
    • 0028557213 scopus 로고
    • Stringent sequence requirements for the formation of human telomeres
    • PMID:8090736
    • Hanish JP, Yanowitz JL, de Lange T. Stringent sequence requirements for the formation of human telomeres. Proc Natl Acad Sci USA 1994; 91:8861- 5; PMID:8090736; http://dx.doi.org/10.1073/pnas.91.19.8861.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8861-8865
    • Hanish, J.P.1    Yanowitz, J.L.2    De Lange, T.3
  • 13
    • 33645747064 scopus 로고    scopus 로고
    • Semi-conservative DNA replication through telomeres requires Taz1
    • PMID:16598261
    • Miller KM, Rog O, Cooper JP. Semi-conservative DNA replication through telomeres requires Taz1. Nature 2006; 440:824-8; PMID:16598261; http://dx.doi.org/10.1038/nature04638.
    • (2006) Nature , vol.440 , pp. 824-828
    • Miller, K.M.1    Rog, O.2    Cooper, J.P.3
  • 14
    • 1942518292 scopus 로고    scopus 로고
    • Anatomy and dynamics of DNA replication fork movement in yeast telomeric regions
    • PMID:15082794
    • Makovets S, Herskowitz I, Blackburn EH. Anatomy and dynamics of DNA replication fork movement in yeast telomeric regions. Mol Cell Biol 2004; 24:4019- 31; PMID:15082794; http://dx.doi.org/10.1128/MCB.24.9.4019-31.2004.
    • (2004) Mol Cell Biol , vol.24 , pp. 4019-4031
    • Makovets, S.1    Herskowitz, I.2    Blackburn, E.H.3
  • 15
    • 67649635974 scopus 로고    scopus 로고
    • Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication
    • PMID:19596237
    • Sfeir A, Kosiyatrakul ST, Hockemeyer D, MacRae SL, Karlseder J, Schildkraut CL, et al. Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication. Cell 2009; 138:90-103; PMID:19596237; http://dx.doi.org/10.1016/j.cell.2009.06.021.
    • (2009) Cell , vol.138 , pp. 90-103
    • Sfeir, A.1    Kosiyatrakul, S.T.2    Hockemeyer, D.3    MacRae, S.L.4    Karlseder, J.5    Schildkraut, C.L.6
  • 16
    • 2942569579 scopus 로고    scopus 로고
    • Telomere-bound TRF1 and TRF2 stall the replication fork at telomeric repeats
    • PMID:15007108
    • Ohki R, Ishikawa F. Telomere-bound TRF1 and TRF2 stall the replication fork at telomeric repeats. Nucleic Acids Res 2004; 32:1627-37; PMID:15007108; http://dx.doi.org/10.1093/nar/gkh309.
    • (2004) Nucleic Acids Res , vol.32 , pp. 1627-1637
    • Ohki, R.1    Ishikawa, F.2
  • 17
    • 65449158366 scopus 로고    scopus 로고
    • Differential arrival of leading and lagging strand DNA polymerases at fission yeast telomeres
    • PMID:19214192
    • Moser BA, Subramanian L, Chang YT, Noguchi C, Noguchi E, Nakamura TM. Differential arrival of leading and lagging strand DNA polymerases at fission yeast telomeres. EMBO J 2009; 28:810-20; PMID:19214192; http://dx.doi.org/10. 1038/emboj.2009.31.
    • (2009) EMBO J , vol.28 , pp. 810-820
    • Moser, B.A.1    Subramanian, L.2    Chang, Y.T.3    Noguchi, C.4    Noguchi, E.5    Nakamura, T.M.6
  • 18
    • 4544250127 scopus 로고    scopus 로고
    • Swi1 and Swi3 are components of a replication fork protection complex in fission yeast
    • PMID:15367656
    • Noguchi E, Noguchi C, McDonald WH, Yates JR, 3rd, Russell P. Swi1 and Swi3 are components of a replication fork protection complex in fission yeast. Mol Cell Biol 2004; 24:8342-55; PMID:15367656; http://dx.doi.org/10.1128/MCB.24. 19.8342-55.2004.
    • (2004) Mol Cell Biol , vol.24 , pp. 8342-8355
    • Noguchi, E.1    Noguchi, C.2    McDonald, W.H.3    Yates III, J.R.4    Russell, P.5
  • 19
    • 33845320139 scopus 로고    scopus 로고
    • Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function
    • PMID:17116885
    • Chou DM, Elledge SJ. Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function. Proc Natl Acad Sci USA 2006; 103:18143-7; PMID:17116885; http://dx.doi.org/10.1073/ pnas.0609251103.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 18143-18147
    • Chou, D.M.1    Elledge, S.J.2
  • 20
    • 33846327177 scopus 로고    scopus 로고
    • Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors
    • PMID:17141802
    • Gotter AL, Suppa C, Emanuel BS. Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors. J Mol Biol 2007; 366:36-52; PMID:17141802; http://dx.doi.org/10.1016/j.jmb.2006.10.097.
    • (2007) J Mol Biol , vol.366 , pp. 36-52
    • Gotter, A.L.1    Suppa, C.2    Emanuel, B.S.3
  • 21
    • 34147201111 scopus 로고    scopus 로고
    • The human Tim/ Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement
    • PMID:17296725
    • Unsal-Kaçmaz K, Chastain PD, Qu PP, Minoo P, Cordeiro-Stone M, Sancar A, et al. The human Tim/ Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. Mol Cell Biol 2007; 27:3131-42; PMID:17296725; http://dx.doi.org/10.1128/MCB.02190-06.
    • (2007) Mol Cell Biol , vol.27 , pp. 3131-3142
    • Unsal-Kaçmaz, K.1    Chastain, P.D.2    Qu, P.P.3    Minoo, P.4    Cordeiro-Stone, M.5    Sancar, A.6
  • 22
    • 16244408025 scopus 로고    scopus 로고
    • Coupling of human circadian and cell cycles by the timeless protein
    • PMID:15798197
    • Unsal-Kaçmaz K, Mullen TE, Kaufmann WK, Sancar A. Coupling of human circadian and cell cycles by the timeless protein. Mol Cell Biol 2005; 25:3109- 16; PMID:15798197; http://dx.doi.org/10.1128/ MCB.25.8.3109-16.2005.
    • (2005) Mol Cell Biol , vol.25 , pp. 3109-3116
    • Unsal-Kaçmaz, K.1    Mullen, T.E.2    Kaufmann, W.K.3    Sancar, A.4
  • 23
    • 34047261441 scopus 로고    scopus 로고
    • Human Tim/Timelessinteracting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint
    • PMID:17102137
    • Yoshizawa-Sugata N, Masai H. Human Tim/Timelessinteracting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint. J Biol Chem 2007; 282:2729-40; PMID:17102137; http://dx.doi.org/10. 1074/jbc.M605596200.
    • (2007) J Biol Chem , vol.282 , pp. 2729-2740
    • Yoshizawa-Sugata, N.1    Masai, H.2
  • 24
    • 77149171759 scopus 로고    scopus 로고
    • Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion
    • PMID:20124417
    • Leman AR, Noguchi C, Lee CY, Noguchi E. Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion. J Cell Sci 2010; 123:660-70; PMID:20124417; http://dx.doi.org/10.1242/jcs.057984.
    • (2010) J Cell Sci , vol.123 , pp. 660-670
    • Leman, A.R.1    Noguchi, C.2    Lee, C.Y.3    Noguchi, E.4
  • 25
    • 0038496744 scopus 로고    scopus 로고
    • Chromosome cohesion is regulated by a clock gene paralogue TIM-1
    • PMID:12827206
    • Chan RC, Chan A, Jeon M, Wu TF, Pasqualone D, Rougvie AE, et al. Chromosome cohesion is regulated by a clock gene paralogue TIM-1. Nature 2003; 424:1002-9; PMID:12827206; http://dx.doi.org/10.1038/nature01697.
    • (2003) Nature , vol.424 , pp. 1002-1009
    • Chan, R.C.1    Chan, A.2    Jeon, M.3    Wu, T.F.4    Pasqualone, D.5    Rougvie, A.E.6
  • 26
    • 35448949105 scopus 로고    scopus 로고
    • Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in Xenopus egg extracts
    • PMID:17846426
    • Errico A, Costanzo V, Hunt T. Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in Xenopus egg extracts. Proc Natl Acad Sci USA 2007; 104:14929-34; PMID:17846426; http://dx.doi.org/10.1073/pnas.0706347104.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 14929-14934
    • Errico, A.1    Costanzo, V.2    Hunt, T.3
  • 27
    • 0142027841 scopus 로고    scopus 로고
    • Swi1 prevents replication fork collapse and controls checkpoint kinase Cds1
    • PMID:14560029
    • Noguchi E, Noguchi C, Du LL, Russell P. Swi1 prevents replication fork collapse and controls checkpoint kinase Cds1. Mol Cell Biol 2003; 23:7861-74; PMID:14560029; http://dx.doi.org/10.1128/MCB.23.21.7861-74.2003.
    • (2003) Mol Cell Biol , vol.23 , pp. 7861-7874
    • Noguchi, E.1    Noguchi, C.2    Du, L.L.3    Russell, P.4
  • 28
    • 0034664767 scopus 로고    scopus 로고
    • Swi1 and swi3 perform imprinting, pausing and termination of DNA replication in S. pombe
    • PMID:11030618
    • Dalgaard JZ, Klar AJ. swi1 and swi3 perform imprinting, pausing and termination of DNA replication in S. pombe. Cell 2000; 102:745-51; PMID:11030618; http://dx.doi.org/10.1016/S0092-8674(00)00063-5.
    • (2000) Cell , vol.102 , pp. 745-751
    • Dalgaard, J.Z.1    Klar, A.J.2
  • 29
    • 0035109312 scopus 로고    scopus 로고
    • Tof1p regulates DNA damage responses during S phase in Saccharomyces cerevisiae
    • PMID:11156979
    • Foss EJ. Tof1p regulates DNA damage responses during S phase in Saccharomyces cerevisiae. Genetics 2001; 157:567-77; PMID:11156979.
    • (2001) Genetics , vol.157 , pp. 567-577
    • Foss, E.J.1
  • 30
    • 34948812991 scopus 로고    scopus 로고
    • Mrc1 and Tof1 regulate DNA replication forks in different ways during normal S phase
    • PMID:17652453
    • Hodgson B, Calzada A, Labib K. Mrc1 and Tof1 regulate DNA replication forks in different ways during normal S phase. Mol Biol Cell 2007; 18:3894-902; PMID:17652453; http://dx.doi.org/10.1091/mbc.E07-05-0500.
    • (2007) Mol Biol Cell , vol.18 , pp. 3894-3902
    • Hodgson, B.1    Calzada, A.2    Labib, K.3
  • 31
    • 4644291834 scopus 로고    scopus 로고
    • Swi1- And swi3-dependent and independent replication fork arrest at the ribosomal DNA of Schizosaccharomyces pombe
    • PMID:15371597
    • Krings G, Bastia D. swi1- and swi3-dependent and independent replication fork arrest at the ribosomal DNA of Schizosaccharomyces pombe. Proc Natl Acad Sci USA 2004; 101:14085-90; PMID:15371597; http://dx.doi.org/10.1073/pnas. 0406037101.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 14085-14090
    • Krings, G.1    Bastia, D.2
  • 32
    • 0024978857 scopus 로고
    • A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
    • PMID:2463488
    • Greider CW, Blackburn EH. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature 1989; 337:331-7; PMID:2463488; http://dx.doi.org/10.1038/337331a0.
    • (1989) Nature , vol.337 , pp. 331-337
    • Greider, C.W.1    Blackburn, E.H.2
  • 33
    • 0024325562 scopus 로고
    • The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
    • PMID:2805070
    • Morin GB. The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell 1989; 59:521-9; PMID:2805070; http://dx.doi.org/10.1016/0092-8674(89)90035-4.
    • (1989) Cell , vol.59 , pp. 521-529
    • Morin, G.B.1
  • 34
    • 0032699183 scopus 로고    scopus 로고
    • Inhibitory effect of telomere- mimic phosphorothioate oligodeoxy nucleotides (S-ODNS) on human tumor cell lines
    • PMID:10545800
    • Saeki T, Takashima S, Tachibana M, Koga M, Hiyama E, Salomon DS, et al. Inhibitory effect of telomere- mimic phosphorothioate oligodeoxy nucleotides (S-ODNS) on human tumor cell lines. Oncology 1999; 57:27-36; PMID:10545800; http://dx.doi.org/10.1159/000055272.
    • (1999) Oncology , vol.57 , pp. 27-36
    • Saeki, T.1    Takashima, S.2    Tachibana, M.3    Koga, M.4    Hiyama, E.5    Salomon, D.S.6
  • 35
    • 0025129726 scopus 로고
    • Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10
    • PMID:1975513
    • Soule HD, Maloney TM, Wolman SR, Peterson WD Jr, Brenz R, McGrath CM, et al. Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. Cancer Res 1990; 50:6075-86; PMID:1975513.
    • (1990) Cancer Res , vol.50 , pp. 6075-6086
    • Soule, H.D.1    Maloney, T.M.2    Wolman, S.R.3    Peterson Jr., W.D.4    Brenz, R.5    McGrath, C.M.6
  • 37
    • 34248658251 scopus 로고    scopus 로고
    • Mrc1, a non-essential DNA replication protein, is required for telomere end protection following loss of capping by Cdc13, Yku or telomerase
    • PMID:17323081
    • Grandin N, Charbonneau M. Mrc1, a non-essential DNA replication protein, is required for telomere end protection following loss of capping by Cdc13, Yku or telomerase. Mol Genet Genomics 2007; 277:685-99; PMID:17323081; http://dx.doi.org/10.1007/s00438-007-0218-0.
    • (2007) Mol Genet Genomics , vol.277 , pp. 685-699
    • Grandin, N.1    Charbonneau, M.2
  • 38
    • 0344441890 scopus 로고    scopus 로고
    • A DNA damage checkpoint response in telomere- initiated senescence
    • Fagagna FdAd. PMID:14608368
    • d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T, et al.; Fagagna FdAd. A DNA damage checkpoint response in telomere- initiated senescence. Nature 2003; 426:194- 8; PMID:14608368; http://dx.doi.org/10.1038/nature02118.
    • (2003) Nature , vol.426 , pp. 194-198
    • D'Adda Di Fagagna, F.1    Reaper, P.M.2    Clay-Farrace, L.3    Fiegler, H.4    Carr, P.5    Von Zglinicki, T.6
  • 39
    • 0042420304 scopus 로고    scopus 로고
    • DNA damage foci at dysfunctional telomeres
    • PMID:12956959
    • Takai H, Smogorzewska A, de Lange T. DNA damage foci at dysfunctional telomeres. Curr Biol 2003; 13:1549-56; PMID:12956959; http://dx.doi.org/10.1016/ S0960-9822(03)00542-6.
    • (2003) Curr Biol , vol.13 , pp. 1549-1556
    • Takai, H.1    Smogorzewska, A.2    De Lange, T.3
  • 40
    • 0344076342 scopus 로고    scopus 로고
    • Comprehensive and definitive molecular cytogenetic characterization of HeLa cells by spectral karyotyping
    • PMID:9892199
    • Macville M, Schröck E, Padilla-Nash H, Keck C, Ghadimi BM, Zimonjic D, et al. Comprehensive and definitive molecular cytogenetic characterization of HeLa cells by spectral karyotyping. Cancer Res 1999; 59:141-50; PMID:9892199.
    • (1999) Cancer Res , vol.59 , pp. 141-150
    • Macville, M.1    Schröck, E.2    Padilla-Nash, H.3    Keck, C.4    Ghadimi, B.M.5    Zimonjic, D.6
  • 41
    • 0034899458 scopus 로고    scopus 로고
    • In vitro reconstitution of the end replication problem
    • PMID:11486015
    • Ohki R, Tsurimoto T, Ishikawa F. In vitro reconstitution of the end replication problem. Mol Cell Biol 2001; 21:5753-66; PMID:11486015; http://dx.doi.org/10.1128/MCB.21.17.5753-66.2001.
    • (2001) Mol Cell Biol , vol.21 , pp. 5753-5766
    • Ohki, R.1    Tsurimoto, T.2    Ishikawa, F.3
  • 42
    • 0022519177 scopus 로고
    • Chromatin assembly during SV40 DNA replication in vitro
    • PMID:3011272
    • Stillman B. Chromatin assembly during SV40 DNA replication in vitro. Cell 1986; 45:555-65; PMID:3011272; http://dx.doi.org/10.1016/0092-8674(86)90287-4.
    • (1986) Cell , vol.45 , pp. 555-565
    • Stillman, B.1
  • 43
    • 0007914702 scopus 로고
    • Simian virus 40 DNA replication in vitro
    • PMID:6095264
    • Li JJ, Kelly TJ. Simian virus 40 DNA replication in vitro. Proc Natl Acad Sci USA 1984; 81:6973- 7; PMID:6095264; http://dx.doi.org/10.1073/pnas.81.22. 6973.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 6973-6977
    • Li, J.J.1    Kelly, T.J.2
  • 44
    • 0036844340 scopus 로고    scopus 로고
    • Recombinational repair and restart of damaged replication forks
    • PMID:12415303
    • McGlynn P, Lloyd RG. Recombinational repair and restart of damaged replication forks. Nat Rev Mol Cell Biol 2002; 3:859-70; PMID:12415303; http://dx.doi.org/10.1038/nrm951.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 859-870
    • McGlynn, P.1    Lloyd, R.G.2
  • 45
    • 68049139532 scopus 로고    scopus 로고
    • Therapeutic doses of hydroxyurea cause telomere dysfunction and reduce TRF2 binding to telomeres
    • PMID:19363303
    • Snyder AR, Zhou J, Deng Z, Lieberman PM. Therapeutic doses of hydroxyurea cause telomere dysfunction and reduce TRF2 binding to telomeres. Cancer Biol Ther 2009; 8:1136-45; PMID:19363303; http://dx.doi.org/10.4161/cbt.8.12.8446.
    • (2009) Cancer Biol Ther , vol.8 , pp. 1136-1145
    • Snyder, A.R.1    Zhou, J.2    Deng, Z.3    Lieberman, P.M.4
  • 46
    • 0034595211 scopus 로고    scopus 로고
    • DNA synthesis at individual replication forks requires the essential initiation factor Cdc45p
    • PMID:10790374
    • Tercero JA, Labib K, Diffley JFX. DNA synthesis at individual replication forks requires the essential initiation factor Cdc45p. EMBO J 2000; 19:2082- 93; PMID:10790374; http://dx.doi.org/10.1093/emboj/19.9.2082.
    • (2000) EMBO J , vol.19 , pp. 2082-2093
    • Tercero, J.A.1    Labib, K.2    Diffley, J.F.X.3
  • 47
    • 0030930990 scopus 로고    scopus 로고
    • Roles of replication protein-A subunits 2 and 3 in DNA replication fork movement in Saccharomyces cerevisiae
    • PMID:9093844
    • Maniar HS, Wilson R, Brill SJ. Roles of replication protein-A subunits 2 and 3 in DNA replication fork movement in Saccharomyces cerevisiae. Genetics 1997; 145:891-902; PMID:9093844.
    • (1997) Genetics , vol.145 , pp. 891-902
    • Maniar, H.S.1    Wilson, R.2    Brill, S.J.3
  • 48
    • 67649768531 scopus 로고    scopus 로고
    • Timeless Maintains Genomic Stability and Suppresses Sister Chromatid Exchange during Unperturbed DNA Replication
    • PMID:19112184
    • Urtishak KA, Smith KD, Chanoux RA, Greenberg RA, Johnson FB, Brown EJ. Timeless Maintains Genomic Stability and Suppresses Sister Chromatid Exchange during Unperturbed DNA Replication. J Biol Chem 2009; 284:8777-85; PMID:19112184; http://dx.doi.org/10.1074/jbc.M806103200.
    • (2009) J Biol Chem , vol.284 , pp. 8777-8785
    • Urtishak, K.A.1    Smith, K.D.2    Chanoux, R.A.3    Greenberg, R.A.4    Johnson, F.B.5    Brown, E.J.6
  • 49
    • 71749086347 scopus 로고    scopus 로고
    • Csm3, Tof1 and Mrc1 form a heterotrimeric mediator complex that associates with DNA replication forks
    • PMID:19819872
    • Bando M, Katou Y, Komata M, Tanaka H, Itoh T, Sutani T, et al. Csm3, Tof1 and Mrc1 form a heterotrimeric mediator complex that associates with DNA replication forks. J Biol Chem 2009; 284:34355- 65; PMID:19819872; http://dx.doi.org/10.1074/jbc.M109.065730.
    • (2009) J Biol Chem , vol.284 , pp. 34355-34365
    • Bando, M.1    Katou, Y.2    Komata, M.3    Tanaka, H.4    Itoh, T.5    Sutani, T.6
  • 50
    • 64249134709 scopus 로고    scopus 로고
    • Telomeres do the (un)twist: Helicase actions at chromosome termini
    • PMID:19245831
    • Chavez A, Tsou AM, Johnson FB. Telomeres do the (un)twist: helicase actions at chromosome termini. Biochim Biophys Acta 2009; 1792:329-40; PMID:19245831.
    • (2009) Biochim Biophys Acta , vol.1792 , pp. 329-340
    • Chavez, A.1    Tsou, A.M.2    Johnson, F.B.3
  • 51
    • 77955842962 scopus 로고    scopus 로고
    • Telomeres: Structures in need of unwinding
    • PMID:20637196
    • Paeschke K, McDonald KR, Zakian VA. Telomeres: structures in need of unwinding. FEBS Lett 2010; 584:3760-72; PMID:20637196; http://dx.doi.org/10. 1016/j.febslet.2010.07.007.
    • (2010) FEBS Lett , vol.584 , pp. 3760-3772
    • Paeschke, K.1    McDonald, K.R.2    Zakian, V.A.3
  • 52
    • 67649639511 scopus 로고    scopus 로고
    • Large-scale expansions of Friedreich's ataxia GAA repeats in yeast
    • PMID:19595718
    • Shishkin AA, Voineagu I, Matera R, Cherng N, Chernet BT, Krasilnikova MM, et al. Large-scale expansions of Friedreich's ataxia GAA repeats in yeast. Mol Cell 2009; 35:82-92; PMID:19595718; http://dx.doi.org/10.1016/j.molcel.2009.06. 017.
    • (2009) Mol Cell , vol.35 , pp. 82-92
    • Shishkin, A.A.1    Voineagu, I.2    Matera, R.3    Cherng, N.4    Chernet, B.T.5    Krasilnikova, M.M.6
  • 53
    • 59649105477 scopus 로고    scopus 로고
    • Replisome stalling and stabilization at CGG repeats, which are responsible for chromosomal fragility
    • PMID:19136957
    • Voineagu I, Surka CF, Shishkin AA, Krasilnikova MM, Mirkin SM. Replisome stalling and stabilization at CGG repeats, which are responsible for chromosomal fragility. Nat Struct Mol Biol 2009; 16:226- 8; PMID:19136957; http://dx.doi.org/10.1038/nsmb.1527.
    • (2009) Nat Struct Mol Biol , vol.16 , pp. 226-228
    • Voineagu, I.1    Surka, C.F.2    Shishkin, A.A.3    Krasilnikova, M.M.4    Mirkin, S.M.5
  • 54
    • 48249141027 scopus 로고    scopus 로고
    • Replication stalling at unstable inverted repeats: Interplay between DNA hairpins and fork stabilizing proteins
    • PMID:18632578
    • Voineagu I, Narayanan V, Lobachev KS, Mirkin SM. Replication stalling at unstable inverted repeats: interplay between DNA hairpins and fork stabilizing proteins. Proc Natl Acad Sci USA 2008; 105:9936- 41; PMID:18632578; http://dx.doi.org/10.1073/pnas.0804510105.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 9936-9941
    • Voineagu, I.1    Narayanan, V.2    Lobachev, K.S.3    Mirkin, S.M.4
  • 55
    • 40649114958 scopus 로고    scopus 로고
    • Mrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms
    • (Amst) PMID:18321795
    • Razidlo DF, Lahue RS. Mrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms. DNA Repair (Amst) 2008; 7:633-40; PMID:18321795; http://dx.doi.org/10.1016/j.dnarep.2008.01.009.
    • (2008) DNA Repair , vol.7 , pp. 633-640
    • Razidlo, D.F.1    Lahue, R.S.2
  • 56
    • 0030970087 scopus 로고    scopus 로고
    • TRF1 is a dimer and bends telomeric DNA
    • PMID:9130722
    • Bianchi A, Smith S, Chong L, Elias P, de Lange T. TRF1 is a dimer and bends telomeric DNA. EMBO J 1997; 16:1785-94; PMID:9130722; http://dx.doi.org/ 10.1093/emboj/16.7.1785.
    • (1997) EMBO J , vol.16 , pp. 1785-1794
    • Bianchi, A.1    Smith, S.2    Chong, L.3    Elias, P.4    De Lange, T.5
  • 57
    • 0031038170 scopus 로고    scopus 로고
    • Regulation of telomere length and function by a Myb-domain protein in fission yeast
    • PMID:9034194
    • Cooper JP, Nimmo ER, Allshire RC, Cech TR. Regulation of telomere length and function by a Myb-domain protein in fission yeast. Nature 1997; 385:744-7; PMID:9034194; http://dx.doi.org/10.1038/385744a0.
    • (1997) Nature , vol.385 , pp. 744-747
    • Cooper, J.P.1    Nimmo, E.R.2    Allshire, R.C.3    Cech, T.R.4
  • 58
    • 74049122810 scopus 로고    scopus 로고
    • In vivo stoichiometry of shelterin components
    • PMID:19864690
    • Takai KK, Hooper S, Blackwood S, Gandhi R, de Lange T. In vivo stoichiometry of shelterin components. J Biol Chem 2010; 285:1457-67; PMID:19864690; http://dx.doi.org/10.1074/jbc.M109.038026.
    • (2010) J Biol Chem , vol.285 , pp. 1457-1467
    • Takai, K.K.1    Hooper, S.2    Blackwood, S.3    Gandhi, R.4    De Lange, T.5
  • 59
    • 25444495864 scopus 로고    scopus 로고
    • The mating type switchactivating protein Sap1 Is required for replication fork arrest at the rRNA genes of fission yeast
    • PMID:16166653
    • Mejía-Ramírez E, Sánchez-Gorostiaga A, Krimer DB, Schvartzman JB, Hernández P. The mating type switchactivating protein Sap1 Is required for replication fork arrest at the rRNA genes of fission yeast. Mol Cell Biol 2005; 25:8755-61; PMID:16166653; http://dx.doi.org/10.1128/MCB. 25.19.8755-61.2005.
    • (2005) Mol Cell Biol , vol.25 , pp. 8755-8761
    • Mejía-Ramírez, E.1    Sánchez-Gorostiaga, A.2    Krimer, D.B.3    Schvartzman, J.B.4    Hernández, P.5
  • 60
    • 56049104484 scopus 로고    scopus 로고
    • Rtf1-mediated eukaryotic site-specific replication termination
    • PMID:18723894
    • Eydmann T, Sommariva E, Inagawa T, Mian S, Klar AJS, Dalgaard JZ. Rtf1-mediated eukaryotic site-specific replication termination. Genetics 2008; 180:27-39; PMID:18723894; http://dx.doi.org/10.1534/genetics.108.089243.
    • (2008) Genetics , vol.180 , pp. 27-39
    • Eydmann, T.1    Sommariva, E.2    Inagawa, T.3    Mian, S.4    Klar, A.J.S.5    Dalgaard, J.Z.6
  • 61
    • 70349194379 scopus 로고    scopus 로고
    • A non-canonical function of topoisomerase II in disentangling dysfunctional telomeres
    • PMID:19680223
    • Germe T, Miller K, Cooper JP. A non-canonical function of topoisomerase II in disentangling dysfunctional telomeres. EMBO J 2009; 28:2803-11; PMID:19680223; http://dx.doi.org/10.1038/emboj.2009.223.
    • (2009) EMBO J , vol.28 , pp. 2803-2811
    • Germe, T.1    Miller, K.2    Cooper, J.P.3
  • 62
    • 78649670285 scopus 로고    scopus 로고
    • Hypoxia suppression of Bim and Bmf blocks anoikis and luminal clearing during mammary morphogenesis
    • PMID:20861305
    • Whelan KA, Caldwell SA, Shahriari KS, Jackson SR, Franchetti LD, Johannes GJ, et al. Hypoxia suppression of Bim and Bmf blocks anoikis and luminal clearing during mammary morphogenesis. Mol Biol Cell 2010; 21:3829-37; PMID:20861305; http://dx.doi.org/10.1091/mbc.E10-04-0353.
    • (2010) Mol Biol Cell , vol.21 , pp. 3829-3837
    • Whelan, K.A.1    Caldwell, S.A.2    Shahriari, K.S.3    Jackson, S.R.4    Franchetti, L.D.5    Johannes, G.J.6
  • 63
    • 68949198783 scopus 로고    scopus 로고
    • TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres
    • PMID:19716786
    • Deng Z, Norseen J, Wiedmer A, Riethman H, Lieberman PM. TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres. Mol Cell 2009; 35:403-13; PMID:19716786; http://dx.doi.org/10.1016/j.molcel. 2009.06.025.
    • (2009) Mol Cell , vol.35 , pp. 403-413
    • Deng, Z.1    Norseen, J.2    Wiedmer, A.3    Riethman, H.4    Lieberman, P.M.5
  • 64
    • 0037370498 scopus 로고    scopus 로고
    • A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
    • PMID:12590264
    • Rubinson DA, Dillon CP, Kwiatkowski AV, Sievers C, Yang L, Kopinja J, et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet 2003; 33:401-6; PMID:12590264; http://dx.doi.org/10.1038/ng1117.
    • (2003) Nat Genet , vol.33 , pp. 401-406
    • Rubinson, D.A.1    Dillon, C.P.2    Kwiatkowski, A.V.3    Sievers, C.4    Yang, L.5    Kopinja, J.6
  • 66
    • 0036059104 scopus 로고    scopus 로고
    • Telomere biology and cellular aging in nonhuman primate cells
    • PMID:11777339
    • Steinert S, White DM, Zou Y, Shay JW, Wright WE. Telomere biology and cellular aging in nonhuman primate cells. Exp Cell Res 2002; 272:146- 52; PMID:11777339; http://dx.doi.org/10.1006/excr.2001.5409.
    • (2002) Exp Cell Res , vol.272 , pp. 146-152
    • Steinert, S.1    White, D.M.2    Zou, Y.3    Shay, J.W.4    Wright, W.E.5
  • 68
    • 45949088031 scopus 로고    scopus 로고
    • Analysis of Telomere Length and Telomerase Activity
    • Coligan JE, Ed. New York, NY: John Wiley and Sons, Inc.
    • Hathcock KS, Hodes RJ, Weng N-P. Analysis of Telomere Length and Telomerase Activity. In: Coligan JE, Ed. Current Protocols in Immunology. New York, NY: John Wiley and Sons, Inc. 2004.
    • (2004) Current Protocols in Immunology
    • Hathcock, K.S.1    Hodes, R.J.2    Weng, N.-P.3
  • 69
    • 77956255536 scopus 로고    scopus 로고
    • FEN1 ensures telomere stability by facilitating replication fork re-initiation
    • PMID:20551483
    • Saharia A, Teasley DC, Duxin JP, Dao B, Chiappinelli KB, Stewart SA. FEN1 ensures telomere stability by facilitating replication fork re-initiation. J Biol Chem 2010; 285:27057-66; PMID:20551483; http://dx.doi.org/10.1074/jbc.M110. 112276.
    • (2010) J Biol Chem , vol.285 , pp. 27057-27066
    • Saharia, A.1    Teasley, D.C.2    Duxin, J.P.3    Dao, B.4    Chiappinelli, K.B.5    Stewart, S.A.6
  • 70
    • 33847661809 scopus 로고    scopus 로고
    • Protocol for the fast chromatin immunoprecipitation (ChIP) method
    • PMID:17406230
    • Nelson JD, Denisenko O, Bomsztyk K. Protocol for the fast chromatin immunoprecipitation (ChIP) method. Nat Protoc 2006; 1:179-85; PMID:17406230; http://dx.doi.org/10.1038/nprot.2006.27.
    • (2006) Nat Protoc , vol.1 , pp. 179-185
    • Nelson, J.D.1    Denisenko, O.2    Bomsztyk, K.3
  • 71
    • 0034749425 scopus 로고    scopus 로고
    • DNA damage-dependent nuclear dynamics of the Mre11 complex
    • PMID:11113202
    • Mirzoeva OK, Petrini JH. DNA damage-dependent nuclear dynamics of the Mre11 complex. Mol Cell Biol 2001; 21:281-8; PMID:11113202; http://dx.doi.org/ 10.1128/MCB.21.1.281-8.2001.
    • (2001) Mol Cell Biol , vol.21 , pp. 281-288
    • Mirzoeva, O.K.1    Petrini, J.H.2
  • 72
    • 0035241668 scopus 로고    scopus 로고
    • Improvements in cytogenetic slide preparation: Controlled chromosome spreading, chemical aging and gradual denaturing
    • PMID:11169574
    • Henegariu O, Heerema NA, Lowe Wright L, Bray-Ward P, Ward DC, Vance GH. Improvements in cytogenetic slide preparation: controlled chromosome spreading, chemical aging and gradual denaturing. Cytometry 2001; 43:101-9; PMID:11169574; http://dx.doi.org/10.1002/1097-0320(20010201)43:2<101::AIDCYTO1024>3.0. CO;2-8.
    • (2001) Cytometry , vol.43 , pp. 101-109
    • Henegariu, O.1    Heerema, N.A.2    Lowe Wright, L.3    Bray-Ward, P.4    Ward, D.C.5    Vance, G.H.6
  • 74
    • 0036670615 scopus 로고    scopus 로고
    • Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres
    • PMID:12196391
    • Nakamura TM, Moser BA, Russell P. Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres. Genetics 2002; 161:1437-52; PMID:12196391.
    • (2002) Genetics , vol.161 , pp. 1437-1452
    • Nakamura, T.M.1    Moser, B.A.2    Russell, P.3
  • 75
    • 39449099352 scopus 로고    scopus 로고
    • RFCCtf18 and the Swi1-Swi3 complex function in separate and redundant pathways required for the stabilization of replication forks to facilitate sister chromatid cohesion in Schizosaccharomyces pombe
    • PMID:18045993
    • Ansbach AB, Noguchi C, Klansek IW, Heidlebaugh M, Nakamura TM, Noguchi E. RFCCtf18 and the Swi1-Swi3 complex function in separate and redundant pathways required for the stabilization of replication forks to facilitate sister chromatid cohesion in Schizosaccharomyces pombe. Mol Biol Cell 2008; 19:595-607; PMID:18045993; http://dx.doi.org/10.1091/mbc.E07-06-0618.
    • (2008) Mol Biol Cell , vol.19 , pp. 595-607
    • Ansbach, A.B.1    Noguchi, C.2    Klansek, I.W.3    Heidlebaugh, M.4    Nakamura, T.M.5    Noguchi, E.6


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