메뉴 건너뛰기




Volumn 16, Issue 7, 1997, Pages 1785-1794

TRF1 is a dimer and bends telomeric DNA

Author keywords

DNA bending; Myb; Rap1p; Telomeric protein; TRF1

Indexed keywords

CURVED DNA; DIMER; DNA BINDING PROTEIN; ONCOPROTEIN; REPETITIVE DNA;

EID: 0030970087     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.7.1785     Document Type: Article
Times cited : (281)

References (68)
  • 1
    • 0030272689 scopus 로고    scopus 로고
    • Telomerase and cancer: Revisiting the telomere hypothesis
    • Autexier,C. and Greider,C.W. (1996) Telomerase and cancer: revisiting the telomere hypothesis. Trends Biol. Sci., 21, 387-391.
    • (1996) Trends Biol. Sci. , vol.21 , pp. 387-391
    • Autexier, C.1    Greider, C.W.2
  • 2
    • 0028096731 scopus 로고
    • A novel DNA binding protein with homology to Myb oncoproteins containing only one repeat can function as a transcriptional activator
    • Baranowskij,N., Frohberg,C., Prat,S. and Willmitzer,L. (1994) A novel DNA binding protein with homology to Myb oncoproteins containing only one repeat can function as a transcriptional activator. EMBO J., 13, 5383-5392.
    • (1994) EMBO J. , vol.13 , pp. 5383-5392
    • Baranowskij, N.1    Frohberg, C.2    Prat, S.3    Willmitzer, L.4
  • 4
    • 0000884978 scopus 로고
    • Using the two-hybrid system to detect protein-protein interaction
    • Harley,D.A. (ed.), IRL Press at Oxford University Press
    • Bartel,P.L., Chien,C., Sternglanz,R. and Fields,S. (1993) Using the two-hybrid system to detect protein-protein interaction. In Harley,D.A. (ed.), Cellular Interactions in Development: A Practical Approach. IRL Press at Oxford University Press, pp. 153-179.
    • (1993) Cellular Interactions in Development: A Practical Approach , pp. 153-179
    • Bartel, P.L.1    Chien, C.2    Sternglanz, R.3    Fields, S.4
  • 6
    • 0010526741 scopus 로고
    • Telomerase
    • Gesteland,R.F. and Atkins,J.F. (eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Blackburn,E.H. (1993) Telomerase. In Gesteland,R.F. and Atkins,J.F. (eds), The RNA World. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 557-576.
    • (1993) The RNA World , pp. 557-576
    • Blackburn, E.H.1
  • 7
    • 0027393752 scopus 로고
    • An essential yeast gene encoding a TTAGGG repeat-binding protein
    • Brigati,C., Kurtz,S., Balderes,D., Vidali,G. and Shore,D. (1993) An essential yeast gene encoding a TTAGGG repeat-binding protein. Mol. Cell. Biol., 13, 1306-1314.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1306-1314
    • Brigati, C.1    Kurtz, S.2    Balderes, D.3    Vidali, G.4    Shore, D.5
  • 10
    • 0025222442 scopus 로고
    • RAP1 protein interacts with yeast telomeres in vivo: Overproduction alters telomere structure and decreases chromosome stability
    • Conrad,M.N., Wright,J.H., Wolf,A.J. and Zakian,V.A. (1990) RAP1 protein interacts with yeast telomeres in vivo: overproduction alters telomere structure and decreases chromosome stability. Cell, 63, 739-750.
    • (1990) Cell , vol.63 , pp. 739-750
    • Conrad, M.N.1    Wright, J.H.2    Wolf, A.J.3    Zakian, V.A.4
  • 11
    • 8244260768 scopus 로고    scopus 로고
    • A Myb-domain protein regulates telomere length and function in fission yeast
    • in press
    • Cooper,J., Nimmo,E., Allshire,R. and Cech,T. (1997) A Myb-domain protein regulates telomere length and function in fission yeast. Nature, in press.
    • (1997) Nature
    • Cooper, J.1    Nimmo, E.2    Allshire, R.3    Cech, T.4
  • 12
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells with express telomerase activity
    • Counter,C.M., Avilion,A.A., LeFeuvre,C.E., Stewart,N.G., Greider,C.W., Harley,C.B. and Bacchetti,S. (1992) Telomere shortening associated with chromosome instability is arrested in immortal cells with express telomerase activity. EMBO J., 11, 1921-1929.
    • (1992) EMBO J. , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avilion, A.A.2    LeFeuvre, C.E.3    Stewart, N.G.4    Greider, C.W.5    Harley, C.B.6    Bacchetti, S.7
  • 14
    • 0027633627 scopus 로고
    • BPF-1, a pathogen-induced DNA-binding protein involved in the plant defense response
    • da Costa e Silva,O., Klein,L., Schmelzer,E., Trezzini,G.F. and Hahlbrock,K. (1993) BPF-1, a pathogen-induced DNA-binding protein involved in the plant defense response. Plant J., 4, 125-135.
    • (1993) Plant J. , vol.4 , pp. 125-135
    • Da Costa E Silva, O.1    Klein, L.2    Schmelzer, E.3    Trezzini, G.F.4    Hahlbrock, K.5
  • 15
    • 0002309826 scopus 로고
    • Telomere dynamics and genome instability in human cancer
    • Blackburn,E.H. and Greider,C.W. (eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • de Lange,T. (1995) Telomere dynamics and genome instability in human cancer. In Blackburn,E.H. and Greider,C.W. (eds), Telomeres. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 265-295.
    • (1995) Telomeres , pp. 265-295
    • De Lange, T.1
  • 17
    • 0026502328 scopus 로고
    • Cloning of Drosophila transcription factor Adf-1 reveals homology to Myb oncoproteins
    • England,B.P., Admon,A. and Tjian,R. (1991) Cloning of Drosophila transcription factor Adf-1 reveals homology to Myb oncoproteins. Proc. Natl Acad. Sci. USA, 89, 683-687.
    • (1991) Proc. Natl Acad. Sci. USA , vol.89 , pp. 683-687
    • England, B.P.1    Admon, A.2    Tjian, R.3
  • 18
    • 0025770257 scopus 로고
    • Functional reintroduction of human telomeres into mammalian cells
    • Farr,C., Fantes,J., Goodfellow,P. and Cooke,H. (1991) Functional reintroduction of human telomeres into mammalian cells. Proc. Natl Acad. Sci. USA, 88, 7006-7010.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 7006-7010
    • Farr, C.1    Fantes, J.2    Goodfellow, P.3    Cooke, H.4
  • 20
    • 0024406857 scopus 로고
    • A novel genetic system to detect protein-protein interaction
    • Fields,S. and Song,O. (1989) A novel genetic system to detect protein-protein interaction. Nature, 340, 245-246.
    • (1989) Nature , vol.340 , pp. 245-246
    • Fields, S.1    Song, O.2
  • 22
    • 0027298713 scopus 로고
    • Distortion of the DNA double helix by RAP1 at silencers and multiple telomeric binding sites
    • Gilson,E., Roberge,M., Giraldo,R., Rhodes,D. and Gasser,S.M. (1993) Distortion of the DNA double helix by RAP1 at silencers and multiple telomeric binding sites. J. Mol. Biol., 231, 293-310.
    • (1993) J. Mol. Biol. , vol.231 , pp. 293-310
    • Gilson, E.1    Roberge, M.2    Giraldo, R.3    Rhodes, D.4    Gasser, S.M.5
  • 23
    • 0020645052 scopus 로고
    • Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast
    • Guarente,L. (1983) Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast. Methods Enzymol., 101, 181-191.
    • (1983) Methods Enzymol. , vol.101 , pp. 181-191
    • Guarente, L.1
  • 24
    • 0028557213 scopus 로고
    • Stringent sequence requirements for telomere formation in human cells
    • Hanish,J.P., Yanowitz,J. and de Lange,T. (1994) Stringent sequence requirements for telomere formation in human cells. Proc. Natl Acad. Sci. USA, 91, 8861-8865.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 8861-8865
    • Hanish, J.P.1    Yanowitz, J.2    De Lange, T.3
  • 25
    • 0001934324 scopus 로고
    • Telomeres and aging
    • Blackburn,E.H. and Greider,C.W. (eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Harley,C.B. (1995) Telomeres and aging. In Blackburn,E.H. and Greider,C.W. (eds), Telomeres. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 247-265.
    • (1995) Telomeres , pp. 247-265
    • Harley, C.B.1
  • 27
    • 0029018708 scopus 로고
    • Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system
    • Hollenberg,S.M., Sternglanz,R., Cheng,P.F. and Weintraub,H. (1995) Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system. Mol. Cell. Biol., 15, 3813-3822.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3813-3822
    • Hollenberg, S.M.1    Sternglanz, R.2    Cheng, P.F.3    Weintraub, H.4
  • 28
    • 0023403099 scopus 로고
    • GCN4, a eukaryotic transcriptional activator protein, binds as a dimer to target DNA
    • Hope,I.A. and Struhl,K. (1987) GCN4, a eukaryotic transcriptional activator protein, binds as a dimer to target DNA. EMBO J., 6, 2781-2784.
    • (1987) EMBO J. , vol.6 , pp. 2781-2784
    • Hope, I.A.1    Struhl, K.2
  • 29
    • 0028342824 scopus 로고
    • DNA-binding domain and recognition sequence of the yeast BAS1 protein, a divergent member of the Myb family of transcription factors
    • Hovring,P.I., Bostad,A., Ording,E., Myrset,A.H. and Gabrielsen,O.S. (1994) DNA-binding domain and recognition sequence of the yeast BAS1 protein, a divergent member of the Myb family of transcription factors. J. Biol. Chem., 269, 17663-17669.
    • (1994) J. Biol. Chem. , vol.269 , pp. 17663-17669
    • Hovring, P.I.1    Bostad, A.2    Ording, E.3    Myrset, A.H.4    Gabrielsen, O.S.5
  • 30
    • 0029963828 scopus 로고    scopus 로고
    • The crystal structure of the DNA-binding domain of yeast RAP1 in complex with telomeric DNA
    • Konig,P., Giraldo,R., Chapman,L. and Rhodes,D. (1996) The crystal structure of the DNA-binding domain of yeast RAP1 in complex with telomeric DNA. Cell, 85, 125-136.
    • (1996) Cell , vol.85 , pp. 125-136
    • Konig, P.1    Giraldo, R.2    Chapman, L.3    Rhodes, D.4
  • 31
    • 0022706076 scopus 로고
    • Variations of intramolecular ligation rates allow the detection of protein-induced bends in DNA
    • Kotlarz,D., Fritsch,A. and Buc,H. (1986) Variations of intramolecular ligation rates allow the detection of protein-induced bends in DNA. EMBO J., 5, 799-803.
    • (1986) EMBO J. , vol.5 , pp. 799-803
    • Kotlarz, D.1    Fritsch, A.2    Buc, H.3
  • 32
    • 0029743764 scopus 로고    scopus 로고
    • Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats
    • Krauskopf,A. and Blackburn,E.H. (1996) Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats. Nature, 383, 354-357.
    • (1996) Nature , vol.383 , pp. 354-357
    • Krauskopf, A.1    Blackburn, E.H.2
  • 33
    • 0026657008 scopus 로고
    • C-terminal truncation of RAP1 results in the deregulation of telomere size, stability, and function in Saccharomyces cerevisiae
    • Kyrion,G., Boakye,K.A. and Lustig,A.J. (1992) C-terminal truncation of RAP1 results in the deregulation of telomere size, stability, and function in Saccharomyces cerevisiae. Mol. Cell. Biol., 12, 5159-5173.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 5159-5173
    • Kyrion, G.1    Boakye, K.A.2    Lustig, A.J.3
  • 34
    • 0028091868 scopus 로고
    • Isolation and functional analysis of a Kluyveromyces lactis RAP1 homologue
    • Larson,G.P., Castanotto,D., Rossi,J.J. and Malafa,M.P. (1994) Isolation and functional analysis of a Kluyveromyces lactis RAP1 homologue. Gene, 150, 35-1.
    • (1994) Gene , vol.150 , pp. 35-41
    • Larson, G.P.1    Castanotto, D.2    Rossi, J.J.3    Malafa, M.P.4
  • 35
    • 0029778954 scopus 로고    scopus 로고
    • A novel mechanism for telomere size control in Saccharomyces cerevisiae
    • Li,B. and Lustig,A.J. (1996) A novel mechanism for telomere size control in Saccharomyces cerevisiae. Genes Dev., 10, 1310-1326.
    • (1996) Genes Dev. , vol.10 , pp. 1310-1326
    • Li, B.1    Lustig, A.J.2
  • 36
    • 0026029612 scopus 로고
    • A yeast protein that binds to vertebrate telomeres and conversed yeast telomeric junctions
    • Liu,Z. and Tye,B.-K. (1991) A yeast protein that binds to vertebrate telomeres and conversed yeast telomeric junctions. Genes Dev., 5, 49-59.
    • (1991) Genes Dev. , vol.5 , pp. 49-59
    • Liu, Z.1    Tye, B.-K.2
  • 37
  • 38
    • 0028446507 scopus 로고
    • A novel DNA-binding domain in the Shrunken initiator-binding protein (IBP1)
    • Lugert,T. and Werr,W. (1994) A novel DNA-binding domain in the Shrunken initiator-binding protein (IBP1). Plant Mol. Biol., 25, 493-506.
    • (1994) Plant Mol. Biol. , vol.25 , pp. 493-506
    • Lugert, T.1    Werr, W.2
  • 39
    • 0024973811 scopus 로고
    • A mutant with a defect in telomere elongation leads to senescence in yeast
    • Lundblad,V. and Szostak,J.W. (1989) A mutant with a defect in telomere elongation leads to senescence in yeast. Cell, 57, 633-643.
    • (1989) Cell , vol.57 , pp. 633-643
    • Lundblad, V.1    Szostak, J.W.2
  • 40
    • 0025252456 scopus 로고
    • Involvement of the silencer and UAS binding protein RAP1 in regulation of telomere length
    • Lustig,A.J., Kurtz,S. and Shore,D. (1990) Involvement of the silencer and UAS binding protein RAP1 in regulation of telomere length. Science, 250, 549-553.
    • (1990) Science , vol.250 , pp. 549-553
    • Lustig, A.J.1    Kurtz, S.2    Shore, D.3
  • 41
    • 0029102354 scopus 로고
    • Runaway telomere elongation caused by telomerase RNA gene mutations
    • McEachern,M.J. and Blackburn,E.H. (1995) Runaway telomere elongation caused by telomerase RNA gene mutations. Nature, 376, 403-409.
    • (1995) Nature , vol.376 , pp. 403-409
    • McEachern, M.J.1    Blackburn, E.H.2
  • 42
    • 0024325562 scopus 로고
    • The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
    • Morin,G.B. (1989) The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell, 59, 521-529.
    • (1989) Cell , vol.59 , pp. 521-529
    • Morin, G.B.1
  • 43
    • 0027510020 scopus 로고
    • A bipartite DNA-binding domain in yeast Reb1p
    • Morrow,B.E., Ju,Q. and Warner,J.R. (1993) A bipartite DNA-binding domain in yeast Reb1p. Mol. Cell. Biol., 13, 1173-1182.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1173-1182
    • Morrow, B.E.1    Ju, Q.2    Warner, J.R.3
  • 45
    • 0028589212 scopus 로고
    • Imaging the asymmetrical DNA bend induced by repressor activator protein 1 with scanning tunneling microscopy
    • Muller,T., Gilson,E., Schmidt,R., Giraldo,R., Sogo,J., Gross,H. and Gasser,S.M. (1994) Imaging the asymmetrical DNA bend induced by repressor activator protein 1 with scanning tunneling microscopy. J. Struct. Biol., 113, 1-12.
    • (1994) J. Struct. Biol. , vol.113 , pp. 1-12
    • Muller, T.1    Gilson, E.2    Schmidt, R.3    Giraldo, R.4    Sogo, J.5    Gross, H.6    Gasser, S.M.7
  • 46
    • 0028138773 scopus 로고
    • Solution structure of a specific DNA complex of the Myb DNA-binding domain with cooperative recognition helices
    • Ogata,K., Morikawa,S., Nakamura,H., Sekikawa,A., Inoue,T., Kanai,H., Sarai,A., Ishii,S. and Nishimura,Y. (1994) Solution structure of a specific DNA complex of the Myb DNA-binding domain with cooperative recognition helices. Cell, 79, 639-648.
    • (1994) Cell , vol.79 , pp. 639-648
    • Ogata, K.1    Morikawa, S.2    Nakamura, H.3    Sekikawa, A.4    Inoue, T.5    Kanai, H.6    Sarai, A.7    Ishii, S.8    Nishimura, Y.9
  • 49
    • 0028174134 scopus 로고
    • The Myb oncogene product induces DNA-bending
    • Saikumar,P., Gabriel,J.L. and Reddy,E.P. (1994) The Myb oncogene product induces DNA-bending. Oncogene, 9, 1279-1287.
    • (1994) Oncogene , vol.9 , pp. 1279-1287
    • Saikumar, P.1    Gabriel, J.L.2    Reddy, E.P.3
  • 50
    • 0025087145 scopus 로고
    • Role of tryptophan repeats and flanking amino acids in Myb-DNA interactions
    • Saikumar,P., Murali,R. and Reddy,E.P. (1990) Role of tryptophan repeats and flanking amino acids in Myb-DNA interactions. Proc. Natl Acad. Sci. USA, 87, 8452-8456.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 8452-8456
    • Saikumar, P.1    Murali, R.2    Reddy, E.P.3
  • 51
    • 0027421043 scopus 로고
    • Loss of a yeast telomere: Arrest, recovery, and chromosome loss
    • Sandell,L. and Zakian,V. (1993) Loss of a yeast telomere: arrest, recovery, and chromosome loss. Cell, 75, 729-741.
    • (1993) Cell , vol.75 , pp. 729-741
    • Sandell, L.1    Zakian, V.2
  • 52
    • 0028130685 scopus 로고
    • RAP1: A protean regulator in yeast
    • Shore,D. (1994) RAP1: a protean regulator in yeast. Trends Genet., 10, 408-12.
    • (1994) Trends Genet. , vol.10 , pp. 408-412
    • Shore, D.1
  • 53
    • 0027944347 scopus 로고
    • TLC1: Template RNA component of Saccharomyces cerevisiae telomerase
    • Singer,M.S. and Gottschling,D.E. (1994) TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science, 266, 404-409.
    • (1994) Science , vol.266 , pp. 404-409
    • Singer, M.S.1    Gottschling, D.E.2
  • 55
    • 0031040086 scopus 로고    scopus 로고
    • TRF1, a mammalian telomeric protein
    • Smith,S. and de Lange,T. (1997) TRF1, a mammalian telomeric protein. Trends Genet., 13, 21-26.
    • (1997) Trends Genet. , vol.13 , pp. 21-26
    • Smith, S.1    De Lange, T.2
  • 56
    • 0029394940 scopus 로고
    • MYB.Ph3 transcription factor from Petunia hybrida induces similar DNA-bending/distortions on its two types of binding site
    • Solano,R., Nieto,C. and Paz-Ares,J. (1995) MYB.Ph3 transcription factor from Petunia hybrida induces similar DNA-bending/distortions on its two types of binding site. Plant J., 8, 673-682.
    • (1995) Plant J. , vol.8 , pp. 673-682
    • Solano, R.1    Nieto, C.2    Paz-Ares, J.3
  • 57
    • 0028948315 scopus 로고
    • DNA-binding and chromatin localization properties of CHD1
    • Stokes,D.G. and Perry,R.P. (1995) DNA-binding and chromatin localization properties of CHD1. Mol. Cell. Biol., 15, 2745-2753.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2745-2753
    • Stokes, D.G.1    Perry, R.P.2
  • 58
    • 0023771741 scopus 로고
    • Empirical estimation of protein-induced bending angles: Applications to 1 site specific recombination complexes
    • Thompson,J.F. and Landy,A. (1988) Empirical estimation of protein-induced bending angles: applications to 1 site specific recombination complexes. Nucleic Acids Res., 16, 9687-9705.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 9687-9705
    • Thompson, J.F.1    Landy, A.2
  • 59
    • 0027299443 scopus 로고
    • DNA target selectivity by the vitamin D3 receptor: Mechanism of dimer binding to an asymmetric repeat element
    • Towers,T.L., Luisi,B.F., Asianov,A. and Freedman,L.P. (1993) DNA target selectivity by the vitamin D3 receptor: mechanism of dimer binding to an asymmetric repeat element. Proc. Natl Acad. Sci. USA, 90, 6310-6314.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 6310-6314
    • Towers, T.L.1    Luisi, B.F.2    Asianov, A.3    Freedman, L.P.4
  • 60
    • 0031027618 scopus 로고    scopus 로고
    • Control of telomere length by the human telomeric protein TRF1
    • in press
    • van Steensel,B. and de Lange,T. (1997) Control of telomere length by the human telomeric protein TRF1. Nature, in press.
    • (1997) Nature
    • Van Steensel, B.1    De Lange, T.2
  • 61
    • 0024328696 scopus 로고
    • Asymmetric DNA bending induced by the yeast multifunctional factor TUF
    • Vignais,M.-L. and Sentenac,A. (1989) Asymmetric DNA bending induced by the yeast multifunctional factor TUF. J. Biol. Chem., 264, 8463-8466.
    • (1989) J. Biol. Chem. , vol.264 , pp. 8463-8466
    • Vignais, M.-L.1    Sentenac, A.2
  • 62
    • 0025007621 scopus 로고
    • A truncated human chromosome 16 associated with a thalassaemia is stabilized by addition of telomeric repeat (TTAGGG)n
    • Wilkie,A.O.M., Lamb,J., Harris,P.C., Finney,R.D. and Higgs,D.R. (1990) A truncated human chromosome 16 associated with a thalassaemia is stabilized by addition of telomeric repeat (TTAGGG)n. Nature, 346, 868-871.
    • (1990) Nature , vol.346 , pp. 868-871
    • Wilkie, A.O.M.1    Lamb, J.2    Harris, P.C.3    Finney, R.D.4    Higgs, D.R.5
  • 63
    • 0021268779 scopus 로고
    • The locus of sequence-directed and protein-induced DNA bending
    • Wu,H.M. and Crothers,D.M. (1984) The locus of sequence-directed and protein-induced DNA bending. Nature, 308, 509-513.
    • (1984) Nature , vol.308 , pp. 509-513
    • Wu, H.M.1    Crothers, D.M.2
  • 64
    • 0025279059 scopus 로고
    • In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs
    • Yu,G.-L., Bradley,J.D., Attardi,L.D. and Blackburn,E.H. (1990) In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs. Nature, 344, 126-132.
    • (1990) Nature , vol.344 , pp. 126-132
    • Yu, G.-L.1    Bradley, J.D.2    Attardi, L.D.3    Blackburn, E.H.4
  • 65
    • 0002672219 scopus 로고
    • Saccharomyces telomeres: Function, structure and replication
    • Blackburn,E.H. and Greider,C.W. (eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Zakian,V.A. (1995a) Saccharomyces telomeres: function, structure and replication. In Blackburn,E.H. and Greider,C.W. (eds), Telomeres. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 107-138.
    • (1995) Telomeres , pp. 107-138
    • Zakian, V.A.1
  • 66
    • 0029563009 scopus 로고
    • Telomeres: Beginning to understand the end
    • Zakian,V.A. (1995b) Telomeres: beginning to understand the end. Science, 270, 1601-1607.
    • (1995) Science , vol.270 , pp. 1601-1607
    • Zakian, V.A.1
  • 67
    • 0028071873 scopus 로고
    • The yeast activator HAP1-a Ga14 family member-binds DNA in a directly repeated orientation
    • Zhang,L. and Guarente,L. (1994) The yeast activator HAP1-a Ga14 family member-binds DNA in a directly repeated orientation. Genes Dev., 8, 2110-2119.
    • (1994) Genes Dev. , vol.8 , pp. 2110-2119
    • Zhang, L.1    Guarente, L.2
  • 68
    • 0026668731 scopus 로고
    • A mammalian factor that binds telomeric TTAGGG repeats in vitro
    • Zhong,Z., Shiue,L., Kaplan,S. and de Lange,T. (1992) A mammalian factor that binds telomeric TTAGGG repeats in vitro. Mol. Cell. Biol., 13, 4834-4843.
    • (1992) Mol. Cell. Biol. , vol.13 , pp. 4834-4843
    • Zhong, Z.1    Shiue, L.2    Kaplan, S.3    De Lange, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.