Optimal insulin treatment in syngeneic islet transplantation

Cell Transplantation

Volumn 9, Issue 1, 2000, Pages 11-18

  Merino, Juan F ^a   Nacher, Victor ^a   Raurell, Mercè ^a   Biarnés, Montserrat ^a   Soler, Joan ^a   Montanya, Eduard ^a,b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

Author keywords

Beta cell mass; Glucose toxicity; Insulin; Islet transplantation

Indexed keywords

INSULIN; STREPTOZOCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; DIABETES MELLITUS; GLUCOSE TOLERANCE; HYPERGLYCEMIA; INSULIN TREATMENT; ISOGRAFT; MALE; MOUSE; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL;

EID: 0033921805     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.1177/096368970000900102     Document Type: Article

References (37)

1. Alejandro, R.; Lehmann, R.; Ricordi, C.; Kenyon, N. S.; Angelico, M. C.; Burke, G.; Esquenazi, V.; Nery, J.; Betancourt, A. E.; Kong, S. S.; Miller, J.; Mintz, D. H. Long term function (6 years) of islet allografts in type I diabetes. Diabetes 46:1983-1989; 1997.
2. Andersson, A.; Korsgren, O.; Jansson, L. Intraportally transplanted pancreatic islets revascularized from hepatic arterial system. Diabetes 38(Suppl. 1): 192-195; 1989.
3. Bonner-Weir, S.; Trent, D. F.; Weir, G. C. Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release. J. Clin. Invest. 71:1544-1554; 1983.
4. Davalli, A. M.; Scaglia, L.; Zangen, D. H.; Hollister, J.; Bonner-Weir, S.; Weir, G. C. Vulnerability of islets in the immediate posttransplantation period. Dynamic changes in structure and function. Diabetes 45:1161-1167; 1996.
5. Davalli, A. M.; Ricordi, C.; Socci, C.; Braghi, S.; Bertuzzi, F.; Fattor, B.; Di Carlo, V.; Pontiroli, A. E.; Pozza, G. Abnormal sensitivity to glucose of human islets cultured in a high glucose medium: Partial reversibility after an additional culture in a normal glucose medium. J. Clin. Endocrinol. Metab. 72:202-208; 1991.
6. Dionne, K. E.; Colton, C. K.; Yarmush, M. L. Effect of oxygen on isolated pancreatic tissue. Trans. Am. Soc. Artif. Intern. Org. XXXV:739-741; 1989.
7. Dionne, K. E.; Colton, C. K.; Yarmush, M. L. Effect of hypoxia on insulin secretion by isolated rat and canine islets of Langerhans. Diabetes 42:12-21; 1993.
8. Eizirik, D. L.; Jansson, L.; Flodstrom, M.; Hellerström, C.; Andersson, A. Mechanisms of defective glucose-induced insulin release in human pancreatic islets transplanted to diabetic nude mice. J. Clin. Endocrinol. Metab. 82:2660-2663; 1997.
9. Eizirik, D.; Korbutt, G. S.; Hellerström, C. Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the beta cell function. J. Clin. Invest. 90:1263-1268; 1992.
10. Jansson, L.; Eizirik, D. L.; Pipeleers, D. G.; Borg, L. A.; Hellerström, C.; Andersson, A. Impairment of glucose-induced insulin secretion in human pancreatic islets transplanted to diabetic nude mice. J. Clin. Invest 96:721-726; 1995.
11. Jansson, S.; Sandler, S. Influence of hyperglycemia on blood perfusion of autotransplanted pancreatic islets in diabetic rats. Diabetes 38(Suppl. 1):196-198; 1989.
12. Juang, J. H.; Bonner-Weir, S.; Wu, Y. J.; Weir, G. C. Beneficial influence of glycemic control upon the growth and function of transplanted islets. Diabetes 43:1334-1339; 1994.
13. Kaiser, N.; Corcos, A. P.; Sarel, I.; Cerasi, E. Monolayer culture of adult rat pancreatic islets on extracellular matrix: Modulation of B-cell function by chronic exposure to high glucose. Endocrinology 129:2067-2076; 1991.
14. Keymeulen, B.; Vetri, M.; Gorus, F.; Vanbrabandt, B.; Pipeleers, D. G. The effect of insulin treatment on function of intraportally grafted islets in streptozocin-diabetic rats. Transplantation 56:60-64; 1993.
15. Korsgren, O.; Jansson, L.; Andersson, A. Effects of hyperglycemia on function of isolated mouse pancreatic islets transplanted under kidney capsule. Diabetes 38:510-515; 1989.
16. Korsgren, O.; Janson, L.; Sandler, S.; Andersson, A. Hyperglycemia-induced B cell toxicity. The late of pancreatic islets transplanted into diabetic mice is dependent on their genetic background. J. Clin. Invest. 86:2161-2168; 1990.
17. Lager, I.; Lönnroth, P.; Von Schenck, H.; Smith, U. Reversal of insulin resistance in type 1 diabetes after treatment with continuous subcutaneous insulin infusion. Br. Med. J. 287:1001-1004; 1983.
18. Leahy, J. L.; Bonner Weir, S.; Weir, G. C. β-cell dysfunction induced by chronic hyperglycemia. Diabetes Care 15: 442-455; 1992.
19. Leahy, J. L.; Weir, G. C. Evolution of abnormal insulin secretory responses during 48 h. in vivo hyperglycemia. Diabetes 37:217-222; 1988.
20. Leiter, E. H. Analysis of differential survival of syngeneic islets transplanted into hyperglycemic C57BL/6J versus C57BL/ksJ mice. Transplantation 44:401-406; 1987.
21. Menger, M. D.; Jaeger, S.; Walter, P.; Feifel, G.; Hammersen, F.; Messmer, K. Angiogenesis and hemodynamics of microvasculature of transplanted islets of Langerhans. Diabetes 38(Suppl. 1):199-201; 1989.
22. Menger, M. D.; Vajkoczy, P.; Leiderer, R.; Jager, S.; Messmer, K. Influence of experimental hyperglycemia on microvascular blood perfusion of pancreatic islets isografts. J. Clin. Invest. 90:1361-1369; 1992.
23. Merino, J. F.; Naeher, V.; Raurell, M.; Aranda, O.; Soler, J.; Montanya, E. Improved outcome of islet transplantation in insulin-treated diabetic mice: Effects on beta-cell mass and function. Diabetologia 40:1004-1010; 1997.
24. Montaña, E.; Bonner-Weir, S.; Weir, G. C. Beta cell mass and growth after syngeneic islet cell transplantation in normal and streptozocin diabetic C57BL/6 mice. J. Clin. Invest. 91:780-787; 1993.
25. Montaña, E.; Bonner-Weir, S.; Weir, G. C. Transplanted beta cell response to increased metabolic demand. Changes in beta cell replication and mass. J. Clin. Invest. 93:1577-1582; 1994.
26. Nacher, V.; Merino, J. F.; Raurell, M.; Soler, E.; Montanya. E. Normoglycemia restores β-cell replicative response to glucose in transplanted islets exposed to chronic hyperglycemia. Diabetes 47:192-196; 1998.
27. Nacher, V.; Raurell, M.; Merino, J. F.; Aranda, O.; Soler, J.; Montana, E. Beta cell growth and mass are preserved in long-term syngeneic islet transplantation in streptozocin-induced diabetic Lewis rats. Diabetes 45:1541-1546; 1996.
28. Ozhato, H.; Porter, J.; Monaco, A.; Montana, E.; Maki, T. Minimun number of islets required to maintain euglycemia and their reduced immunogenicity after transplantation into diabetic mice. Transplantation 56:270-274; 1993.
29. Purrello, F.; Vetri, M.; Gatta, C.; Gullo, D.; Vigneri, R. Effects of high glucose on insulin secretion by isolated rat islets and purified beta cells and possible role of glycosylation. Diabetes 38:1417-1422; 1988.
30. Robertson, R. P.; Oson, L. K.; Zhang, H. J. Differentiating glucose toxicity from glucose desensitisation: A new message from the insulin gene. Diabetes 43:1085-1089; 1994.
31. Rossetti, L.; Shulman, G. I.; Zawalich, W.; DeFronzo, R. A. Effect of chronic hyperglycemia on in vivo insulin secretion in partially pancreatectomized rats. J. Clin. Invest. 80:1037-1044; 1987.
32. Rossetti, L.; Laughlin, M. R. Correction of chronic hyperglycemia with vanadate but not with phlorizin, normalizes in vivo glycogen repletion and in vitro glycogen synthase activity in diabetic skeletal muscle. J. Clin. Invest. 84; 892-899; 1989.
33. Sandler, S.; Jansson, L. Blood flow measurements in autotransplanted pancreatic islets on the rat. Impairment of the blood perfusion of the graft during hyperglycemia. J. Clin. Invest. 80:17-21; 1987.
34. Vuorinen-Markkola, H.; Koivisto, V. A.; Yki-Jarvinen, H. Mechanisms of hyperglycemia-induced insulin resistance in whole body and skeletal muscle of type 1 diabetic patients. Diabetes 41:571-580; 1992.
35. Warnock, G. L.; Kneteman, N. M.; Rajotte, R. V. Effect of diabetes on the function of transplanted human islets of Langerhans. Transplant. Proc. 22:804-805; 1990.
36. Yki-Järvinen. Glucose toxicity. Endocr. Rev. 13:415-431; 1992.
37. Yki-Järvinen, H.; Helve, E.; Koivisto, V. A. Hyperglycemia decreases glucose uptake in type 1 diabetes. Diabetes 36:892-896; 1987.