Protective unfolded protein response in human pancreatic beta cells transplanted into mice

PLoS ONE

Volumn 5, Issue 6, 2010, Pages

  Kennedy, Jeffrey ^a   Katsuta, Hitoshi ^a   Jung, Min Ho ^a   Marselli, Lorella ^a   Goldfine, Allison B ^a   Balis, Ulysses J ^b   Sgroi, Dennis ^b   Bonner Weir, Susan ^a   Weir, Gordon C ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; MEMBRANE PROTEIN; PROTEIN IRE1; PROTEIN KINASE LIKE ENDOPLASMIC RETICULUM KINASE; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BIOTINYLATION; CELL TRANSPLANTATION; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERGLYCEMIA; LASER CAPTURE MICRODISSECTION; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SCID MOUSE; UPREGULATION; ANIMAL; CYTOLOGY; ENDOPLASMIC RETICULUM; GLUCOSE BLOOD LEVEL; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; MOUSE MUTANT; PANCREAS ISLET; PANCREAS ISLET TRANSPLANTATION; PROTEIN DENATURATION;

MUS;

ANIMALS; APOPTOSIS; BLOOD GLUCOSE; ENDOPLASMIC RETICULUM; HUMANS; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, INBRED ICR; MICE, SCID; PROTEIN DENATURATION;

EID: 77955341234     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011211     Document Type: Article

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