메뉴 건너뛰기




Volumn 58, Issue , 2012, Pages 193-223

Urinary Metabolomics in Newborns and Infants

Author keywords

Biomarkers; Infant; Metabolomics; Newborn; Nutrimetabolomics; Pharmametabolomics; Prediction; Urine

Indexed keywords


EID: 84862571524     PISSN: 00652423     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-394383-5.00013-8     Document Type: Chapter
Times cited : (36)

References (109)
  • 1
    • 2942709840 scopus 로고    scopus 로고
    • Metabolic profiles to define the genome: can we hear the phenotypes?
    • Griffin J.L. Metabolic profiles to define the genome: can we hear the phenotypes?. Philos. Trans. R. Soc. Lond. B: Biol. Sci. 2004, 359:857-871.
    • (2004) Philos. Trans. R. Soc. Lond. B: Biol. Sci. , vol.359 , pp. 857-871
    • Griffin, J.L.1
  • 2
    • 77957932050 scopus 로고    scopus 로고
    • Metabolomics: the " new clinical chemistry" for personalized neonatal medicine
    • Antonucci R., Atzori L., Barberini L., Fanos V. Metabolomics: the " new clinical chemistry" for personalized neonatal medicine. Minerva Pediatr. 2010, 62(S1):145-148.
    • (2010) Minerva Pediatr. , vol.62 , Issue.S1 , pp. 145-148
    • Antonucci, R.1    Atzori, L.2    Barberini, L.3    Fanos, V.4
  • 4
    • 78650315006 scopus 로고    scopus 로고
    • Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy
    • Dunn W.B., Broadhurst D.I., Atherton H.J., Goodacre R., Griffin J.L. Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy. Chem. Soc. Rev. 2011, 40:387-426.
    • (2011) Chem. Soc. Rev. , vol.40 , pp. 387-426
    • Dunn, W.B.1    Broadhurst, D.I.2    Atherton, H.J.3    Goodacre, R.4    Griffin, J.L.5
  • 5
    • 0032892964 scopus 로고    scopus 로고
    • Secondary metabolite biosynthesis: the first century
    • Bentley R. Secondary metabolite biosynthesis: the first century. Crit. Rev. Biotechnol. 1999, 19:1-40.
    • (1999) Crit. Rev. Biotechnol. , vol.19 , pp. 1-40
    • Bentley, R.1
  • 7
    • 78650737804 scopus 로고    scopus 로고
    • Advances in structure elucidation of small molecules using mass spectrometry
    • Kind T., Fiehn O. Advances in structure elucidation of small molecules using mass spectrometry. Bioanal. Rev. 2010, 2:23-60.
    • (2010) Bioanal. Rev. , vol.2 , pp. 23-60
    • Kind, T.1    Fiehn, O.2
  • 8
    • 79954545526 scopus 로고    scopus 로고
    • An introduction to biological nuclear magnetic resonance spectroscopy
    • [Epub ahead of print]
    • Bothwell G.H., Griffin J.L. An introduction to biological nuclear magnetic resonance spectroscopy. Biol. Rev. Camb. Philos. Soc. 2010, [Epub ahead of print]. 10.1111/j.1469-185X.2010.00157.x.
    • (2010) Biol. Rev. Camb. Philos. Soc.
    • Bothwell, G.H.1    Griffin, J.L.2
  • 9
    • 0035160371 scopus 로고    scopus 로고
    • A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations
    • Raamsdonk L.M., Teusink B., Broadhurst D., Zhang N., Hayes A., Walsh M.C., et al. A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations. Nat. Biotechnol. 2001, 19:45-50.
    • (2001) Nat. Biotechnol. , vol.19 , pp. 45-50
    • Raamsdonk, L.M.1    Teusink, B.2    Broadhurst, D.3    Zhang, N.4    Hayes, A.5    Walsh, M.C.6
  • 10
    • 33750719994 scopus 로고    scopus 로고
    • Global systems biology, personalized medicine and molecular epidemiology
    • Nicholson J.K. Global systems biology, personalized medicine and molecular epidemiology. Mol. Syst. Biol. 2006, 2:52. 10.1038/msb4100095.
    • (2006) Mol. Syst. Biol. , vol.2 , pp. 52
    • Nicholson, J.K.1
  • 12
    • 0031686598 scopus 로고    scopus 로고
    • Effect of slow growth on metabolism of Escherichia coli, as revealed by global metabolite pool (" metabolome" ) analysis
    • Tweeddale H., Notley-McRobb L., Ferenci T. Effect of slow growth on metabolism of Escherichia coli, as revealed by global metabolite pool (" metabolome" ) analysis. J. Bacteriol. 1998, 180:5109-5116.
    • (1998) J. Bacteriol. , vol.180 , pp. 5109-5116
    • Tweeddale, H.1    Notley-McRobb, L.2    Ferenci, T.3
  • 13
    • 53749085229 scopus 로고    scopus 로고
    • A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology
    • Herrgard M.J., Swainston N., Dobson P., Dunn W.B., Arga K.Y., Arvas M., et al. A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology. Nat. Biotechnol. 2008, 26:1155-1160.
    • (2008) Nat. Biotechnol. , vol.26 , pp. 1155-1160
    • Herrgard, M.J.1    Swainston, N.2    Dobson, P.3    Dunn, W.B.4    Arga, K.Y.5    Arvas, M.6
  • 14
    • 36348980985 scopus 로고    scopus 로고
    • Current progress in computational metabolomics
    • Wishart D.S. Current progress in computational metabolomics. Brief. Bioinform. 2007, 8:279-293.
    • (2007) Brief. Bioinform. , vol.8 , pp. 279-293
    • Wishart, D.S.1
  • 15
    • 0036007687 scopus 로고    scopus 로고
    • Metabolomics-the link between genotypes and phenotypes
    • Fiehn O. Metabolomics-the link between genotypes and phenotypes. Plant Mol. Biol. 2002, 48:155-171.
    • (2002) Plant Mol. Biol. , vol.48 , pp. 155-171
    • Fiehn, O.1
  • 16
    • 54549091125 scopus 로고    scopus 로고
    • Systems biology: metabonomics
    • Nicholson J.K., Lindon J.C. Systems biology: metabonomics. Nature 2008, 455:1054-1056.
    • (2008) Nature , vol.455 , pp. 1054-1056
    • Nicholson, J.K.1    Lindon, J.C.2
  • 17
    • 85086969575 scopus 로고    scopus 로고
    • Metabolomics comes of age?
    • Preti G. Metabolomics comes of age?. The Scientist 2005, 19:8-12.
    • (2005) The Scientist , vol.19 , pp. 8-12
    • Preti, G.1
  • 18
    • 0015111451 scopus 로고
    • Metabolic profiles: gas-phase methods for analysis of metabolites
    • Horning E.C., Horning M.G. Metabolic profiles: gas-phase methods for analysis of metabolites. Clin. Chem. 1971, 17:802-809.
    • (1971) Clin. Chem. , vol.17 , pp. 802-809
    • Horning, E.C.1    Horning, M.G.2
  • 19
    • 0015131404 scopus 로고
    • Quantitative analysis of urine vapor and breath by gas-liquid partition chromatography
    • Pauling L., Robinson A.B., Teranishi R., Cary P. Quantitative analysis of urine vapor and breath by gas-liquid partition chromatography. Proc. Natl. Acad. Sci. U.S.A. 1971, 68:2374-2376.
    • (1971) Proc. Natl. Acad. Sci. U.S.A. , vol.68 , pp. 2374-2376
    • Pauling, L.1    Robinson, A.B.2    Teranishi, R.3    Cary, P.4
  • 20
    • 0021403120 scopus 로고
    • Use of high-resolution proton nuclear magnetic resonance spectroscopy for rapid multi-component analysis of urine
    • Bales J.R., Higham D.P., Howe I., Nicholson J.K., Sadler P.J. Use of high-resolution proton nuclear magnetic resonance spectroscopy for rapid multi-component analysis of urine. Clin. Chem. 1984, 30:426-432.
    • (1984) Clin. Chem. , vol.30 , pp. 426-432
    • Bales, J.R.1    Higham, D.P.2    Howe, I.3    Nicholson, J.K.4    Sadler, P.J.5
  • 22
    • 0032694577 scopus 로고    scopus 로고
    • 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
    • Nicholson J.K., Lindon J.C., Holmes E. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 1999, 29:1181-1189.
    • (1999) Xenobiotica , vol.29 , pp. 1181-1189
    • Nicholson, J.K.1    Lindon, J.C.2    Holmes, E.3
  • 23
    • 53349117682 scopus 로고    scopus 로고
    • Metabolomics: biochemistry's new look
    • Blow N. Metabolomics: biochemistry's new look. Nature 2008, 455:697-700.
    • (2008) Nature , vol.455 , pp. 697-700
    • Blow, N.1
  • 25
    • 18844406001 scopus 로고    scopus 로고
    • Measuring the metabolome: current analytical technologies
    • Dunn W.B., Bailey N.J., Johnson H.E. Measuring the metabolome: current analytical technologies. Analyst 2005, 130:606-625.
    • (2005) Analyst , vol.130 , pp. 606-625
    • Dunn, W.B.1    Bailey, N.J.2    Johnson, H.E.3
  • 27
    • 85171930921 scopus 로고    scopus 로고
    • Paintomics 2.0. (accessed February ).
    • Paintomics 2.0. (accessed February 2011). http://www.paintomics.org/cgi-bin/main2.cgi.
    • (2011)
  • 28
    • 78650572031 scopus 로고    scopus 로고
    • Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data
    • García-Alcalde F., García-López F., Dopazo J., Conesa A. Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data. Bioinformatics 2011, 27:137-139.
    • (2011) Bioinformatics , vol.27 , pp. 137-139
    • García-Alcalde, F.1    García-López, F.2    Dopazo, J.3    Conesa, A.4
  • 29
    • 84889421961 scopus 로고    scopus 로고
    • John Wiley & Sons Ltd., Chichester, United Kingdom, [1-509]
    • Brereton R.G. Chemometrics for Pattern Recognition 2009, John Wiley & Sons Ltd., Chichester, United Kingdom, [1-509]. 10.1002/9780470746462.
    • (2009) Chemometrics for Pattern Recognition
    • Brereton, R.G.1
  • 30
    • 72549095180 scopus 로고    scopus 로고
    • Chemometrics in metabolomics-a review in human disease diagnosis
    • Madsen R., Lundstedt T., Trygg J. Chemometrics in metabolomics-a review in human disease diagnosis. Anal. Chim. Acta 2010, 659:23-33.
    • (2010) Anal. Chim. Acta , vol.659 , pp. 23-33
    • Madsen, R.1    Lundstedt, T.2    Trygg, J.3
  • 31
    • 38949209075 scopus 로고    scopus 로고
    • NMR based metabolic profiling and metabonomic approaches to problems in molecular toxicology
    • Coen M., Holmes E., Lindon J.C., Nicholson J.K. NMR based metabolic profiling and metabonomic approaches to problems in molecular toxicology. Chem. Res. Toxicol. 2008, 21:9-27.
    • (2008) Chem. Res. Toxicol. , vol.21 , pp. 9-27
    • Coen, M.1    Holmes, E.2    Lindon, J.C.3    Nicholson, J.K.4
  • 35
    • 50249099816 scopus 로고    scopus 로고
    • Metabolic phenotyping in health and disease
    • Holmes E., Wilson I.D., Nicholson J.K. Metabolic phenotyping in health and disease. Cell 2008, 134:714-717.
    • (2008) Cell , vol.134 , pp. 714-717
    • Holmes, E.1    Wilson, I.D.2    Nicholson, J.K.3
  • 36
    • 0031010090 scopus 로고    scopus 로고
    • Measurement of albumin and low molecular weight proteins in the urine of newborn infants using a cotton wool ball collection method
    • Fell J.M., Thakkar H., Newman D.J., et al. Measurement of albumin and low molecular weight proteins in the urine of newborn infants using a cotton wool ball collection method. Acta Paediatr. 1997, 86:518-522.
    • (1997) Acta Paediatr. , vol.86 , pp. 518-522
    • Fell, J.M.1    Thakkar, H.2    Newman, D.J.3
  • 37
    • 0034934783 scopus 로고    scopus 로고
    • Urinary PGE(2) concentrations measured by a new EIA method in infants with urinary tract infections or renal malformations
    • Cuzzolin L., Mangiarotti P., Fanos V. Urinary PGE(2) concentrations measured by a new EIA method in infants with urinary tract infections or renal malformations. Prostaglandins Leukot. Essent. Fatty Acids 2001, 64:317-322.
    • (2001) Prostaglandins Leukot. Essent. Fatty Acids , vol.64 , pp. 317-322
    • Cuzzolin, L.1    Mangiarotti, P.2    Fanos, V.3
  • 39
    • 78650175031 scopus 로고    scopus 로고
    • Recent and potential developments in the analysis of urine: a review
    • Ryan D., Robards K., Prenzler P.D., Kendall M. Recent and potential developments in the analysis of urine: a review. Anal. Chim. Acta 2011, 684:8-20.
    • (2011) Anal. Chim. Acta , vol.684 , pp. 8-20
    • Ryan, D.1    Robards, K.2    Prenzler, P.D.3    Kendall, M.4
  • 43
    • 79959255971 scopus 로고    scopus 로고
    • Reduced progesterone metabolites in human late pregnancy
    • Hill M., Pařízek A., Kancheva R., Jirásek J.E. Reduced progesterone metabolites in human late pregnancy. Physiol. Res. 2010, 60:225-241.
    • (2010) Physiol. Res. , vol.60 , pp. 225-241
    • Hill, M.1    Pařízek, A.2    Kancheva, R.3    Jirásek, J.E.4
  • 44
  • 45
    • 44349102404 scopus 로고    scopus 로고
    • Multidimensional proteomics analysis of amniotic fluid to provide insight into the mechanisms of idiopathic preterm birth
    • Buhimschi I.A., Zhao G., Rosenberg V.A., Abdel-Razeq S., Thung S., Buhimschi C.S. Multidimensional proteomics analysis of amniotic fluid to provide insight into the mechanisms of idiopathic preterm birth. PLoS One 2008, 3:e2049.
    • (2008) PLoS One , vol.3
    • Buhimschi, I.A.1    Zhao, G.2    Rosenberg, V.A.3    Abdel-Razeq, S.4    Thung, S.5    Buhimschi, C.S.6
  • 47
    • 77957240409 scopus 로고    scopus 로고
    • Robust early pregnancy prediction of later preeclampsia using metabolomic biomarkers
    • Kenny L.C., Broadhurst D.I., Dunn W., Brown M., North R.A., McCowan L., et al. Robust early pregnancy prediction of later preeclampsia using metabolomic biomarkers. Hypertension 2010, 56:741-749.
    • (2010) Hypertension , vol.56 , pp. 741-749
    • Kenny, L.C.1    Broadhurst, D.I.2    Dunn, W.3    Brown, M.4    North, R.A.5    McCowan, L.6
  • 48
    • 78149389419 scopus 로고    scopus 로고
    • Impact of prenatal disorders on the metabolic profile of second trimester amniotic fluid: a nuclear magnetic resonance metabonomic study
    • Graca G., Duarte I.F., Barros A.S., Goodfellow B.J., Diaz S.O., Pinto J., et al. Impact of prenatal disorders on the metabolic profile of second trimester amniotic fluid: a nuclear magnetic resonance metabonomic study. J. Proteome Res. 2010, 9:6016-6024.
    • (2010) J. Proteome Res. , vol.9 , pp. 6016-6024
    • Graca, G.1    Duarte, I.F.2    Barros, A.S.3    Goodfellow, B.J.4    Diaz, S.O.5    Pinto, J.6
  • 49
    • 70549092085 scopus 로고    scopus 로고
    • Delivery by Caesarean section, rather than vaginal delivery, promotes hepatic steatosis in piglets
    • Hyde M.J., Griffin J.L., Herrera E., Byrne C.D., Clarke L., Kemp P.R. Delivery by Caesarean section, rather than vaginal delivery, promotes hepatic steatosis in piglets. Clin. Sci. 2009, 118:47-59.
    • (2009) Clin. Sci. , vol.118 , pp. 47-59
    • Hyde, M.J.1    Griffin, J.L.2    Herrera, E.3    Byrne, C.D.4    Clarke, L.5    Kemp, P.R.6
  • 50
    • 67649200145 scopus 로고    scopus 로고
    • Developmental delineation of metabolic-patterns of neonatal mice by using NMR-metabolic profiling on highly-diluted urine
    • Shimizu Y.I., Sunaga E., Aoyagi S., Kanazawa K., Takahashi S., Takahashi Y., et al. Developmental delineation of metabolic-patterns of neonatal mice by using NMR-metabolic profiling on highly-diluted urine. J. Toxicol. Sci. 2009, 34:343-347.
    • (2009) J. Toxicol. Sci. , vol.34 , pp. 343-347
    • Shimizu, Y.I.1    Sunaga, E.2    Aoyagi, S.3    Kanazawa, K.4    Takahashi, S.5    Takahashi, Y.6
  • 51
    • 77956743345 scopus 로고    scopus 로고
    • Metabolomics reveals relationship between plasma inositols and birth weight: possible markers for fetal programming of type 2 diabetes
    • [pii: 378268]
    • Nissen P.M., Nebel C., Oksbjerg N., Bertram H.C. Metabolomics reveals relationship between plasma inositols and birth weight: possible markers for fetal programming of type 2 diabetes. J. Biomed. Biotechnol. 2011, [pii: 378268].
    • (2011) J. Biomed. Biotechnol.
    • Nissen, P.M.1    Nebel, C.2    Oksbjerg, N.3    Bertram, H.C.4
  • 56
    • 56049090767 scopus 로고    scopus 로고
    • Proteomics- and metabolomics-based neonatal diagnostics in assessing and managing the critically ill neonate
    • Spitzer A.R., Chace D. Proteomics- and metabolomics-based neonatal diagnostics in assessing and managing the critically ill neonate. Clin. Perinatol. 2008, 35:695-716.
    • (2008) Clin. Perinatol. , vol.35 , pp. 695-716
    • Spitzer, A.R.1    Chace, D.2
  • 57
    • 25144444439 scopus 로고    scopus 로고
    • Perinatal asphyxia
    • Lippincott, Williams & Wilkins, New York, J.P. Cloherty, R. Stark Ann (Eds.)
    • Aurora S., Snyder E.Y. Perinatal asphyxia. Manual of Neonatal Care 1997, 536-555. Lippincott, Williams & Wilkins, New York. fourth ed. J.P. Cloherty, R. Stark Ann (Eds.).
    • (1997) Manual of Neonatal Care , pp. 536-555
    • Aurora, S.1    Snyder, E.Y.2
  • 58
    • 77949702635 scopus 로고    scopus 로고
    • Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigs
    • Solberg R., Enot D., Deigner H.P., Koal T., Scholl-Bürgi S., Saugstad O.D., et al. Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigs. PLoS One 2010, 5:e9606.
    • (2010) PLoS One , vol.5
    • Solberg, R.1    Enot, D.2    Deigner, H.P.3    Koal, T.4    Scholl-Bürgi, S.5    Saugstad, O.D.6
  • 59
    • 1942422633 scopus 로고    scopus 로고
    • Metabolomic analysis of adrenal lipids during hypoxia in the neonatal rat: implications in steroidogenesis
    • Bruder E.D., Lee P.C., Raff H. Metabolomic analysis of adrenal lipids during hypoxia in the neonatal rat: implications in steroidogenesis. Am. J. Physiol. Endocrinol. Metab. 2004, 286:E697-E703.
    • (2004) Am. J. Physiol. Endocrinol. Metab. , vol.286
    • Bruder, E.D.1    Lee, P.C.2    Raff, H.3
  • 61
    • 77957953807 scopus 로고    scopus 로고
    • A metabolomic approach in an experimental model of hypoxia-reoxygenation in newborn piglets: urine predicts outcome
    • Atzori L., Xanthos T., Barberini L., Antonucci R., Murgia F., Lussu M., et al. A metabolomic approach in an experimental model of hypoxia-reoxygenation in newborn piglets: urine predicts outcome. J. Matern. Fetal Neonatal Med. 2010, 23(S3):134-137.
    • (2010) J. Matern. Fetal Neonatal Med. , vol.23 , Issue.S3 , pp. 134-137
    • Atzori, L.1    Xanthos, T.2    Barberini, L.3    Antonucci, R.4    Murgia, F.5    Lussu, M.6
  • 62
    • 0025110027 scopus 로고
    • Hypoxanthine, xanthine, and uric acid concentration in the cerebrospinal fluid, plasma and urine of hypoxemic pigs
    • Poulsen J.P., Oyasaeter S., Sanderud J., Rognum T.O., Saugstad O.D. Hypoxanthine, xanthine, and uric acid concentration in the cerebrospinal fluid, plasma and urine of hypoxemic pigs. Pediatr. Res. 1990, 28:477-481.
    • (1990) Pediatr. Res. , vol.28 , pp. 477-481
    • Poulsen, J.P.1    Oyasaeter, S.2    Sanderud, J.3    Rognum, T.O.4    Saugstad, O.D.5
  • 64
    • 57149085729 scopus 로고    scopus 로고
    • Correlation between Apgar Score and urinary uric acid to creatinine ratio in perinatal asphyxia
    • Pallab B., Sabyasachi S., Nabendu C., Harendranath D. Correlation between Apgar Score and urinary uric acid to creatinine ratio in perinatal asphyxia. Indian J. Clin. Biochem. 2008, 23:361-364.
    • (2008) Indian J. Clin. Biochem. , vol.23 , pp. 361-364
    • Pallab, B.1    Sabyasachi, S.2    Nabendu, C.3    Harendranath, D.4
  • 65
    • 47249140727 scopus 로고    scopus 로고
    • Can urinary excretion rate of malondialdehyde, uric acid and protein predict the severity and impending death in perinatal asphyxia?
    • Banupriya C., Ratnakar P., Doureradjou N., Mondal N., Vishnu B., Koner B.C. Can urinary excretion rate of malondialdehyde, uric acid and protein predict the severity and impending death in perinatal asphyxia?. Clin. Biochem. 2008, 41:968-973.
    • (2008) Clin. Biochem. , vol.41 , pp. 968-973
    • Banupriya, C.1    Ratnakar, P.2    Doureradjou, N.3    Mondal, N.4    Vishnu, B.5    Koner, B.C.6
  • 66
    • 77957746621 scopus 로고    scopus 로고
    • Metabolomic study on vitamins B1, B2, and PP supplementation to improve serum metabolic profiles in mice under acute hypoxia based on 1H NMR analysis
    • Liu J., Wu J.Q., Yang J.J., Wei J.Y., Gao W.N., Guo C.J. Metabolomic study on vitamins B1, B2, and PP supplementation to improve serum metabolic profiles in mice under acute hypoxia based on 1H NMR analysis. Biomed. Environ. Sci. 2010, 23:312-318.
    • (2010) Biomed. Environ. Sci. , vol.23 , pp. 312-318
    • Liu, J.1    Wu, J.Q.2    Yang, J.J.3    Wei, J.Y.4    Gao, W.N.5    Guo, C.J.6
  • 69
    • 36649020263 scopus 로고    scopus 로고
    • Metabolomics identifies perturbations in human disorders of propionate metabolism
    • Wikoff W., Gangoiti J., Barshop B., Siuzdak G. Metabolomics identifies perturbations in human disorders of propionate metabolism. Clin. Chem. 2007, 53:2169-2176.
    • (2007) Clin. Chem. , vol.53 , pp. 2169-2176
    • Wikoff, W.1    Gangoiti, J.2    Barshop, B.3    Siuzdak, G.4
  • 70
    • 0036713474 scopus 로고    scopus 로고
    • Metabolomics and individual metabolic assessment: the next great challenge for nutrition
    • German J.B., Roberts M.A., Fay L., Watkins S.M. Metabolomics and individual metabolic assessment: the next great challenge for nutrition. J. Nutr. 2002, 132:2486-2487.
    • (2002) J. Nutr. , vol.132 , pp. 2486-2487
    • German, J.B.1    Roberts, M.A.2    Fay, L.3    Watkins, S.M.4
  • 71
    • 77958104174 scopus 로고    scopus 로고
    • Challenges of molecular nutrition research 6: the nutritional phenotype database to store, share and evaluate nutritional systems biology studies
    • van Ommen B., Bouwman J., Dragsted L.O., Drevon C.A., Elliott R., de Groot P., et al. Challenges of molecular nutrition research 6: the nutritional phenotype database to store, share and evaluate nutritional systems biology studies. Genes Nutr. 2010, 5:189-203.
    • (2010) Genes Nutr. , vol.5 , pp. 189-203
    • van Ommen, B.1    Bouwman, J.2    Dragsted, L.O.3    Drevon, C.A.4    Elliott, R.5    de Groot, P.6
  • 72
    • 50149086997 scopus 로고    scopus 로고
    • Application of metabolomics in drug discovery and development
    • Wishart D.S. Application of metabolomics in drug discovery and development. Drugs R&D 2008, 9:307-322.
    • (2008) Drugs R&D , vol.9 , pp. 307-322
    • Wishart, D.S.1
  • 73
    • 33750095958 scopus 로고    scopus 로고
    • Effect of the acute standardization on the urinary, plasma and salivary metabolic profiles of healthy humans
    • Walsh M.C., Brennan L., Malthouse J.P.G., Roche H.M., Gibney M.I. Effect of the acute standardization on the urinary, plasma and salivary metabolic profiles of healthy humans. Am. J. Clin. Nutr. 2006, 84:531-539.
    • (2006) Am. J. Clin. Nutr. , vol.84 , pp. 531-539
    • Walsh, M.C.1    Brennan, L.2    Malthouse, J.P.G.3    Roche, H.M.4    Gibney, M.I.5
  • 74
    • 79251506649 scopus 로고    scopus 로고
    • Dietary intake patterns are reflected in metabolomic profiles: potential role in dietary assessment studies
    • O'Sullivan A., Gibney M.J., Brennan L. Dietary intake patterns are reflected in metabolomic profiles: potential role in dietary assessment studies. Am. J. Clin. Nutr. 2011, 93:314-321.
    • (2011) Am. J. Clin. Nutr. , vol.93 , pp. 314-321
    • O'Sullivan, A.1    Gibney, M.J.2    Brennan, L.3
  • 75
    • 78649735772 scopus 로고    scopus 로고
    • Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting
    • Suhre K., Meisinger C., Döring A., Altmaier E., Belcredi P., Gieger C., et al. Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting. PLoS One 2010, 5:e13953.
    • (2010) PLoS One , vol.5
    • Suhre, K.1    Meisinger, C.2    Döring, A.3    Altmaier, E.4    Belcredi, P.5    Gieger, C.6
  • 76
    • 79551489208 scopus 로고    scopus 로고
    • Personalized medicine in diabetes
    • Malandrino N., Smith R.J. Personalized medicine in diabetes. Clin. Chem. 2011, 57:231-240.
    • (2011) Clin. Chem. , vol.57 , pp. 231-240
    • Malandrino, N.1    Smith, R.J.2
  • 77
    • 79951549589 scopus 로고    scopus 로고
    • Intrauterine growth restriction and postnatal high-protein diet affect the kidneys in adult rats
    • Shen Q., Xu H., Wei L.M., Chen J., Liu H.M. Intrauterine growth restriction and postnatal high-protein diet affect the kidneys in adult rats. Nutrition 2011, 27:364-371.
    • (2011) Nutrition , vol.27 , pp. 364-371
    • Shen, Q.1    Xu, H.2    Wei, L.M.3    Chen, J.4    Liu, H.M.5
  • 78
    • 77955127791 scopus 로고    scopus 로고
    • Effect of postnatal high-protein diet on kidney function of rats exposed to intrauterine protein restriction
    • Chen J., Xu H., Shen Q., Guo W., Sun L. Effect of postnatal high-protein diet on kidney function of rats exposed to intrauterine protein restriction. Pediatr. Res. 2010, 68:100-104.
    • (2010) Pediatr. Res. , vol.68 , pp. 100-104
    • Chen, J.1    Xu, H.2    Shen, Q.3    Guo, W.4    Sun, L.5
  • 80
    • 77957959421 scopus 로고    scopus 로고
    • Fortification of maternal milk for very low birth weight (VLBW) pre-term neonates
    • Reali A., Greco F., Fanaro S., Atzei A., Puddu M., Moi M., et al. Fortification of maternal milk for very low birth weight (VLBW) pre-term neonates. Early Hum. Dev. 2010, 86(S1):33-36.
    • (2010) Early Hum. Dev. , vol.86 , Issue.S1 , pp. 33-36
    • Reali, A.1    Greco, F.2    Fanaro, S.3    Atzei, A.4    Puddu, M.5    Moi, M.6
  • 81
    • 36849092870 scopus 로고    scopus 로고
    • The effects of two different doses of amino acid administrations on growth and blood amino acids in premature neonates admitted to the NICU: a randomized controlled trial
    • Clark R.H., Chace D.H., Spitzer A.R. The effects of two different doses of amino acid administrations on growth and blood amino acids in premature neonates admitted to the NICU: a randomized controlled trial. Pediatrics 2007, 120:1286-1296.
    • (2007) Pediatrics , vol.120 , pp. 1286-1296
    • Clark, R.H.1    Chace, D.H.2    Spitzer, A.R.3
  • 82
    • 33645747471 scopus 로고    scopus 로고
    • Predicting the clinical outcome of congenital unilateral ureteropelvic junction obstruction in newborn by urinary proteome analysis
    • Decramer S., Wittke S., Mischak H., Zürbig P., Walden M., Bouissou F., et al. Predicting the clinical outcome of congenital unilateral ureteropelvic junction obstruction in newborn by urinary proteome analysis. Nat. Med. 2006, 12:398-400.
    • (2006) Nat. Med. , vol.12 , pp. 398-400
    • Decramer, S.1    Wittke, S.2    Mischak, H.3    Zürbig, P.4    Walden, M.5    Bouissou, F.6
  • 83
    • 77955013540 scopus 로고    scopus 로고
    • Urinary proteome analysis identifies infants but not older requiring pyelopasty
    • Drube J., Zürbig P., Schiffer E., Lau E., Ure B., Glüer S., et al. Urinary proteome analysis identifies infants but not older requiring pyelopasty. Pediatr. Nephrol. 2010, 25:1673-1678.
    • (2010) Pediatr. Nephrol. , vol.25 , pp. 1673-1678
    • Drube, J.1    Zürbig, P.2    Schiffer, E.3    Lau, E.4    Ure, B.5    Glüer, S.6
  • 85
    • 77954965747 scopus 로고    scopus 로고
    • Urinary proteome analysis and the management of ureteropelvic junction obstruction
    • Mesrobian H.G. Urinary proteome analysis and the management of ureteropelvic junction obstruction. Pediatr. Nephrol. 2010, 25:1595-1596.
    • (2010) Pediatr. Nephrol. , vol.25 , pp. 1595-1596
    • Mesrobian, H.G.1
  • 86
    • 79251601094 scopus 로고    scopus 로고
    • Metabolomics: biomarkers of disease and drug toxicity
    • Stewart J.D., Bolt H.M. Metabolomics: biomarkers of disease and drug toxicity. Arch. Toxicol. 2011, 85:3-4.
    • (2011) Arch. Toxicol. , vol.85 , pp. 3-4
    • Stewart, J.D.1    Bolt, H.M.2
  • 87
    • 77957281554 scopus 로고    scopus 로고
    • Metabolomics for early detection of drug-induced kidney injury: review of the current status
    • Boudonck K.J., Rose D.J., Karoly E.D., Lee D.P., Lawton K.A., Lapinskas P.J. Metabolomics for early detection of drug-induced kidney injury: review of the current status. Bioanalysis 2009, 1:1645-1663.
    • (2009) Bioanalysis , vol.1 , pp. 1645-1663
    • Boudonck, K.J.1    Rose, D.J.2    Karoly, E.D.3    Lee, D.P.4    Lawton, K.A.5    Lapinskas, P.J.6
  • 89
    • 77957997338 scopus 로고    scopus 로고
    • Metabonomic analysis of serum metabolites in kidney transplant recipients with cyclosporine A- or tacrolimus-based immunosuppression
    • Kim C.D., Kim E.Y., Yoo H., Lee J.W., Ryu do H., Noh D.W., et al. Metabonomic analysis of serum metabolites in kidney transplant recipients with cyclosporine A- or tacrolimus-based immunosuppression. Transplantation 2010, 90:748-756.
    • (2010) Transplantation , vol.90 , pp. 748-756
    • Kim, C.D.1    Kim, E.Y.2    Yoo, H.3    Lee, J.W.4    Ryu do, H.5    Noh, D.W.6
  • 90
    • 36749021190 scopus 로고    scopus 로고
    • The utility of a Rodent Model in detecting pediatric drug-induced nephrotoxicity
    • Espandiari P., Zhang J., Rosenzweig B.A., Vaidya S.V., Sun J., et al. The utility of a Rodent Model in detecting pediatric drug-induced nephrotoxicity. Toxicol. Sci. 2007, 99:637-648.
    • (2007) Toxicol. Sci. , vol.99 , pp. 637-648
    • Espandiari, P.1    Zhang, J.2    Rosenzweig, B.A.3    Vaidya, S.V.4    Sun, J.5
  • 91
    • 77956535305 scopus 로고    scopus 로고
    • Ingenuity pathways analysis of urine metabonomics phenotypes toxicity of gentamicin in multiple organs
    • Lv H., Liu L., Song T., Lu J., Chen X. Ingenuity pathways analysis of urine metabonomics phenotypes toxicity of gentamicin in multiple organs. Mol. Biosyst. 2010, 6:2056-2067.
    • (2010) Mol. Biosyst. , vol.6 , pp. 2056-2067
    • Lv, H.1    Liu, L.2    Song, T.3    Lu, J.4    Chen, X.5
  • 92
    • 79953713653 scopus 로고    scopus 로고
    • The enhanced value of combining conventional and " omics" analyses in early assessment of drug-induced hepatobiliary injury
    • Ellinger-Ziegelbauer H., Adler M., Amberg A., Brandenburg A., Callanan J.J., Connor S., et al. The enhanced value of combining conventional and " omics" analyses in early assessment of drug-induced hepatobiliary injury. Toxicol. Appl. Pharmacol. 2011, 252:97-111.
    • (2011) Toxicol. Appl. Pharmacol. , vol.252 , pp. 97-111
    • Ellinger-Ziegelbauer, H.1    Adler, M.2    Amberg, A.3    Brandenburg, A.4    Callanan, J.J.5    Connor, S.6
  • 93
    • 80051982351 scopus 로고    scopus 로고
    • GC-MS-based metabolomics reveals mechanism of action for hydrazine induced hepatotoxicity in rats
    • [Epub ahead of print]
    • Bando K., Kunimatsu T., Sakai J., Kimura J., Funabashi H., Seki T., et al. GC-MS-based metabolomics reveals mechanism of action for hydrazine induced hepatotoxicity in rats. J. Appl. Toxicol. 2010, [Epub ahead of print]. 10.1002/jat.1591.
    • (2010) J. Appl. Toxicol.
    • Bando, K.1    Kunimatsu, T.2    Sakai, J.3    Kimura, J.4    Funabashi, H.5    Seki, T.6
  • 94
    • 77955919042 scopus 로고    scopus 로고
    • The application of metabonomics to predict drug-induced liver injury
    • O'Connell T.M., Watkins P.B. The application of metabonomics to predict drug-induced liver injury. Clin. Pharmacol. Ther. 2010, 88:394-399.
    • (2010) Clin. Pharmacol. Ther. , vol.88 , pp. 394-399
    • O'Connell, T.M.1    Watkins, P.B.2
  • 95
    • 45849145091 scopus 로고    scopus 로고
    • Application of metabolomics to cardiovascular biomarker and pathway discovery
    • Lewis G.D., Asnani A., Gerszten R.E. Application of metabolomics to cardiovascular biomarker and pathway discovery. J. Am. Coll. Cardiol. 2008, 52:117-123.
    • (2008) J. Am. Coll. Cardiol. , vol.52 , pp. 117-123
    • Lewis, G.D.1    Asnani, A.2    Gerszten, R.E.3
  • 96
    • 79953740856 scopus 로고    scopus 로고
    • Metabolomic distinction and insights into the pathogenesis of human primary dilated cardiomyopathy
    • Alexander D., Lombardi R., Rodriguez G., Mitchell M.M., Marian A.J. Metabolomic distinction and insights into the pathogenesis of human primary dilated cardiomyopathy. Eur. J. Clin. Invest. 2011, 41:527-538.
    • (2011) Eur. J. Clin. Invest. , vol.41 , pp. 527-538
    • Alexander, D.1    Lombardi, R.2    Rodriguez, G.3    Mitchell, M.M.4    Marian, A.J.5
  • 99
    • 84862570573 scopus 로고    scopus 로고
    • Metabolomics & Patent Ductus Arteriosus diagnosis: Is 1H-NMR (nuclear magnetic resonance) spectroscopy of urine at birth predictive as ultrasound?
    • I (abstract)
    • Atzori L., Barberini L., Lussu M., Murgia F., Noto A., Mercuro G., et al. Metabolomics & Patent Ductus Arteriosus diagnosis: Is 1H-NMR (nuclear magnetic resonance) spectroscopy of urine at birth predictive as ultrasound?. J. Matern. Fetal Neonatal Med. 2011, 24(S). I (abstract).
    • (2011) J. Matern. Fetal Neonatal Med. , vol.24 , Issue.S
    • Atzori, L.1    Barberini, L.2    Lussu, M.3    Murgia, F.4    Noto, A.5    Mercuro, G.6
  • 101
    • 77951454811 scopus 로고    scopus 로고
    • NMR-based analysis of metabolites in urine provides rapid diagnosis and etiology of pneumonia
    • Slupsky C.M. NMR-based analysis of metabolites in urine provides rapid diagnosis and etiology of pneumonia. Biomark. Med. 2010, 4:195-197.
    • (2010) Biomark. Med. , vol.4 , pp. 195-197
    • Slupsky, C.M.1
  • 102
    • 77958613720 scopus 로고    scopus 로고
    • Metabolomic analysis in severe childhood pneumonia in the Gambia, West Africa: findings from a pilot study
    • Laiakis E.C., Morris G.A., Fornace A.J., Howie S.R. Metabolomic analysis in severe childhood pneumonia in the Gambia, West Africa: findings from a pilot study. PLoS One 2010, 5:e12655.
    • (2010) PLoS One , vol.5
    • Laiakis, E.C.1    Morris, G.A.2    Fornace, A.J.3    Howie, S.R.4
  • 103
    • 79959362446 scopus 로고    scopus 로고
    • Complex systems in pulmonary medicine: a systems biology approach to lung disease
    • Kaminsky D.A., Irvin C.G., Sterk P.J. Complex systems in pulmonary medicine: a systems biology approach to lung disease. J. Appl. Physiol. 2011, 110:1716-1722.
    • (2011) J. Appl. Physiol. , vol.110 , pp. 1716-1722
    • Kaminsky, D.A.1    Irvin, C.G.2    Sterk, P.J.3
  • 104
    • 78650655173 scopus 로고    scopus 로고
    • Metabolomics of sepsis-induced acute lung injury: a new approach for biomarkers
    • Lacy P. Metabolomics of sepsis-induced acute lung injury: a new approach for biomarkers. Am. J. Physiol. Lung Cell. Mol. Physiol. 2011, 300:L1-L3.
    • (2011) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.300
    • Lacy, P.1
  • 105
    • 78549234074 scopus 로고    scopus 로고
    • Metabolomics and mechanisms: sometimes the fisher catches a big fish
    • Cantor G.H. Metabolomics and mechanisms: sometimes the fisher catches a big fish. Toxicol. Sci. 2010, 118:321-323.
    • (2010) Toxicol. Sci. , vol.118 , pp. 321-323
    • Cantor, G.H.1
  • 107
    • 84862509326 scopus 로고    scopus 로고
    • The kidney in post-asphyctic syndrome: state of the art
    • Hygeia Press, Caglliari, Italy, V. Fanos, R.L. Chevalier, G. Faa, L. Cataldi (Eds.)
    • Fanos V., Atzori L., Dessì A., D'Aloja E., Finco G., Faa G. The kidney in post-asphyctic syndrome: state of the art. Developmental Nephrology: from Embryology to Metabolomics 2011, 159-179. Hygeia Press, Caglliari, Italy. V. Fanos, R.L. Chevalier, G. Faa, L. Cataldi (Eds.).
    • (2011) Developmental Nephrology: from Embryology to Metabolomics , pp. 159-179
    • Fanos, V.1    Atzori, L.2    Dessì, A.3    D'Aloja, E.4    Finco, G.5    Faa, G.6
  • 109
    • 84859383638 scopus 로고    scopus 로고
    • Pharma-metabolomics in Neonatology: is it a Dream or a Fact?
    • F 27. [Epub ahead of print]
    • Fanos V., Barberini L., Antonucci R., Atzori L. Pharma-metabolomics in Neonatology: is it a Dream or a Fact?. Curr. Pharm. Des. 2012 Feb 27., (S). [Epub ahead of print].
    • (2012) Curr. Pharm. Des. , Issue.S
    • Fanos, V.1    Barberini, L.2    Antonucci, R.3    Atzori, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.