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Volumn 23, Issue 12, 2010, Pages 1344-1359

Metabolomics in premature labor: A novel approach to identify patients at risk for preterm delivery

Author keywords

amniocentesis; chorioamnionitis; cytokines; high dimensional biology; intraamniotic infection; intraamniotic inflammation; MIAC; microbial invasion of the amniotic cavity; omics sciences; pregnancy; preterm delivery; Preterm labor

Indexed keywords

6 N METHYLADENINE; ACEGLUTAMIDE; ARACHIDIC ACID; CATECHOL; CHOLESTEROL; FRUCTOSE; GALACTOSE; GLUTAMIC ACID; GLYCEROL; GLYCINE; HEXOSE; INOSITOL; ISOLEUCINE; LEUCINE; MANNOSE; METHIONINE; PHENYLALANINE; PHENYLETHANOLAMINE; PIMELIC ACID; SALICYLAMIDE; SUCCINIC ACID; TRYPTOPHAN; XENOBIOTIC AGENT;

EID: 78349238952     PISSN: 14767058     EISSN: 14764954     Source Type: Journal    
DOI: 10.3109/14767058.2010.482618     Document Type: Article
Times cited : (147)

References (251)
  • 1
    • 0001854984 scopus 로고    scopus 로고
    • The child is the father of the man
    • Romero R. The child is the father of the man. Prenat Neonat Med 1996;8-11.
    • (1996) Prenat Neonat Med , pp. 8-11
    • Romero, R.1
  • 3
    • 70350666468 scopus 로고    scopus 로고
    • Prenatal medicine: The child is the father ofthe man
    • Romero R. Prenatal medicine: the child is the father ofthe man. J Matern Fetal Neonatal Med 2009;22:636-639.
    • (2009) J Matern Fetal Neonatal Med , vol.22 , pp. 636-639
    • Romero, R.1
  • 5
    • 22244453091 scopus 로고    scopus 로고
    • Monocyte chemotactic protein-1 is increased in the amniotic fluid of women who deliver preterm in the presence or absence of intra-amniotic infection
    • Esplin MS, Romero R, Chaiworapongsa T, Kim YM, Edwin S, Gomez R, Mazor M, Adashi EY. Monocyte chemotactic protein-1 is increased in the amniotic fluid of women who deliver preterm in the presence or absence of intra-amniotic infection. J Matern Fetal Neonatal Med 2005;17:365-373.
    • (2005) J Matern Fetal Neonatal Med , vol.17 , pp. 365-373
    • Esplin, M.S.1    Romero, R.2    Chaiworapongsa, T.3    Kim, Y.M.4    Edwin, S.5    Gomez, R.6    Mazor, M.7    Adashi, E.Y.8
  • 6
    • 34248580011 scopus 로고    scopus 로고
    • Human beta-defensin-2: A natural antimicrobial peptide present in amniotic fluid participates in the host response to microbial invasion of the amniotic cavity
    • Soto E, Espinoza J, Nien JK, Kusanovic JP, Erez O, Richani K, Santolaya-Forgas J, Romero R. Human beta-defensin-2: a natural antimicrobial peptide present in amniotic fluid participates in the host response to microbial invasion of the amniotic cavity. J Matern Fetal Neonatal Med 2007;20: 15-22.
    • (2007) J Matern Fetal Neonatal Med , vol.20 , pp. 15-22
    • Soto, E.1    Espinoza, J.2    Nien, J.K.3    Kusanovic, J.P.4    Erez, O.5    Richani, K.6    Santolaya-Forgas, J.7    Romero, R.8
  • 11
  • 13
    • 44649137990 scopus 로고    scopus 로고
    • The frequency and significance of intraamniotic inflammation in patients with cervical insufficiency
    • Lee SE, Romero R, Park CW, Jun JK, Yoon BH. The frequency and significance of intraamniotic inflammation in patients with cervical insufficiency. Am J Obstet Gynecol 2008;198:633-638.
    • (2008) Am J Obstet Gynecol , vol.198 , pp. 633-638
    • Lee, S.E.1    Romero, R.2    Park, C.W.3    Jun, J.K.4    Yoon, B.H.5
  • 15
    • 55749103395 scopus 로고    scopus 로고
    • Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture ofmembranes: An association with subclinical intrauterine infection in preterm parturition
    • Mazaki-Tovi S, Romero R, Kusanovic JP, Erez O, Gotsch F, Mittal P, Than NG, Nhan-Chang CL, Hamill N, Vaisbuch E, et al. Visfatin/Pre-B cell colony-enhancing factor in amniotic fluid in normal pregnancy, spontaneous labor at term, preterm labor and prelabor rupture ofmembranes: an association with subclinical intrauterine infection in preterm parturition. J Perinat Med 2008;36:485-496.
    • (2008) J Perinat Med , vol.36 , pp. 485-496
    • Mazaki-Tovi, S.1    Romero, R.2    Kusanovic, J.P.3    Erez, O.4    Gotsch, F.5    Mittal, P.6    Than, N.G.7    Nhan-Chang, C.L.8    Hamill, N.9    Vaisbuch, E.10
  • 17
    • 51549087617 scopus 로고    scopus 로고
    • Schmidt AM. Soluble receptor for advanced glycation end products (sRAGE) and endogenous secretory RAGE (esRAGE) in amniotic fluid: Modulation by infection and inflammation
    • Romero R, Espinoza J, Hassan S, Gotsch F, Kusanovic JP, Avila C, Erez O, Edwin S, Schmidt AM. Soluble receptor for advanced glycation end products (sRAGE) and endogenous secretory RAGE (esRAGE) in amniotic fluid: modulation by infection and inflammation. J Perinat Med 2008;36:388-398.
    • (2008) J Perinat Med , vol.36 , pp. 388-398
    • Romero, R.1    Espinoza, J.2    Hassan, S.3    Gotsch, F.4    Kusanovic, J.P.5    Avila, C.6    Erez, O.7    Edwin, S.8
  • 31
    • 73949119878 scopus 로고    scopus 로고
    • A subset ofpatients destined to develop spontaneous preterm labor has an abnormal angiogenic/anti-angiogenic profile in maternal plasma: Evidence in support of pathophysiologic heterogeneity of preterm labor derived from a longitudinal study
    • Chaiworapongsa T, Romero R, Tarca A, Pedro KJ, Mittal P, Kwon KS, Gotsch F, Erez O, Vaisbuch E, Mazaki-Tovi S, et al. A subset ofpatients destined to develop spontaneous preterm labor has an abnormal angiogenic/anti-angiogenic profile in maternal plasma: evidence in support of pathophysiologic heterogeneity of preterm labor derived from a longitudinal study. J Matern Fetal Neonatal Med 2009;22:1122-1139.
    • (2009) J Matern Fetal Neonatal Med , vol.22 , pp. 1122-1139
    • Chaiworapongsa, T.1    Romero, R.2    Tarca, A.3    Pedro, K.J.4    Mittal, P.5    Kwon, K.S.6    Gotsch, F.7    Erez, O.8    Vaisbuch, E.9    Mazaki-Tovi, S.10
  • 36
    • 34247127012 scopus 로고    scopus 로고
    • Distribution ofCD14+ and CD68+ macrophages in the placental bed and basal plate of women with preeclampsia and preterm labor
    • Kim JS, Romero R, Cushenberry E, Kim YM, Erez O, Nien JK, Yoon BH, Espinoza J, Kim CJ. Distribution ofCD14+ and CD68+ macrophages in the placental bed and basal plate of women with preeclampsia and preterm labor. Placenta 2007;28:571-576.
    • (2007) Placenta , vol.28 , pp. 571-576
    • Kim, J.S.1    Romero, R.2    Cushenberry, E.3    Kim, Y.M.4    Erez, O.5    Nien, J.K.6    Yoon, B.H.7    Espinoza, J.8    Kim, C.J.9
  • 38
    • 0028506326 scopus 로고
    • A time to be born: Implications ofanimal studies in maternal-fetal medicine
    • Nathanielsz PW. A time to be born: implications ofanimal studies in maternal-fetal medicine. Birth 1994;21:163-169.
    • (1994) Birth , vol.21 , pp. 163-169
    • Nathanielsz, P.W.1
  • 39
    • 0035144398 scopus 로고    scopus 로고
    • Type II phospholipase A2 in preterm human gestational tissues
    • Lappas M, Permezel M, Georgiou HM, Rice GE. Type II phospholipase A2 in preterm human gestational tissues. Placenta 2001;22:64-69.
    • (2001) Placenta , vol.22 , pp. 64-69
    • Lappas, M.1    Permezel, M.2    Georgiou, H.M.3    Rice, G.E.4
  • 41
    • 0037238577 scopus 로고    scopus 로고
    • Expression and localization of prostaglandin e synthase isoforms in human fetal membranes in term and preterm labor
    • Meadows JW, Eis AL, Brockman DE, Myatt L. Expression and localization of prostaglandin E synthase isoforms in human fetal membranes in term and preterm labor. J Clin Endocrinol Metab 2003;88:433-439.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 433-439
    • Meadows, J.W.1    Eis, A.L.2    De, B.3    Myatt, L.4
  • 42
    • 4043137505 scopus 로고    scopus 로고
    • Paradoxical proin-flammatory actions of interleukin-10 in human amnion: Potential roles in term and preterm labour
    • Mitchell MD, Simpson KL, Keelan JA. Paradoxical proin-flammatory actions of interleukin-10 in human amnion: potential roles in term and preterm labour. J Clin Endocrinol Metab 2004;89:4149-4152.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 4149-4152
    • Mitchell, M.D.1    Simpson, K.L.2    Keelan, J.A.3
  • 43
    • 33746832938 scopus 로고    scopus 로고
    • Cervical ripening: Biochemical, molecular, and clinical considerations
    • Maul H, Mackay L, Garfield RE. Cervical ripening: biochemical, molecular, and clinical considerations. Clin Obstet Gynecol 2006;49:551-563.
    • (2006) Clin Obstet Gynecol , vol.49 , pp. 551-563
    • Maul, H.1    MacKay, L.2    Garfield, R.E.3
  • 45
    • 33847257011 scopus 로고    scopus 로고
    • Identification of human term and preterm labor using artificial neural networks on uterine electromyography data
    • Maner WL, Garfield RE. Identification of human term and preterm labor using artificial neural networks on uterine electromyography data. Ann Biomed Eng 2007;35:465-473.
    • (2007) Ann Biomed Eng , vol.35 , pp. 465-473
    • Maner, W.L.1    Garfield, R.E.2
  • 46
    • 40849120248 scopus 로고    scopus 로고
    • Cytokine signaling, inflammation, innate immunity and preterm labour-aworkshopreport
    • Blank V, Hirsch E, Challis JR, Romero R, Lye SJ. Cytokine signaling, inflammation, innate immunity and preterm labour-aworkshopreport. Placenta 2008;29 (Suppl A):S102-S104.
    • (2008) Placenta , vol.29 , Issue.SUPPL. A
    • Blank, V.1    Hirsch, E.2    Challis, J.R.3    Romero, R.4    Lye, S.J.5
  • 47
    • 54949158279 scopus 로고    scopus 로고
    • Effect of calcium ionophore A23187 on prostaglandin synthase type 2 and 15-hydroxy-prostaglandin dehydrogenase expression in human chorion trophoblast cells
    • Casciani V, Premyslova M, Luo D, Marinoni E, Moscarini M, Di Iorio R, Challis JR. Effect of calcium ionophore A23187 on prostaglandin synthase type 2 and 15-hydroxy-prostaglandin dehydrogenase expression in human chorion trophoblast cells. Am J Obstet Gynecol 2008;199:554-558.
    • (2008) Am J Obstet Gynecol , vol.199 , pp. 554-558
    • Casciani, V.1    Premyslova, M.2    Luo, D.3    Marinoni, E.4    Moscarini, M.5    Di Iorio, R.6    Challis, J.R.7
  • 48
    • 49049111873 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 (CCL-2) integrates mechanical and endocrine signals that mediate term and preterm labor
    • Shynlova O, Tsui P, Dorogin A, Lye SJ. Monocyte chemoattractant protein-1 (CCL-2) integrates mechanical and endocrine signals that mediate term and preterm labor. J Immunol 2008;181:1470-1479.
    • (2008) J Immunol , vol.181 , pp. 1470-1479
    • Shynlova, O.1    Tsui, P.2    Dorogin, A.3    Lye, S.J.4
  • 50
    • 60549107016 scopus 로고    scopus 로고
    • Transcriptional regulation of the processes of human labour and delivery
    • Lappas M, Rice GE. Transcriptional regulation of the processes of human labour and delivery. Placenta 2009;30 (Suppl A):S90-S95.
    • (2009) Placenta , vol.30 , Issue.SUPPL. A
    • Lappas, M.1    Rice, G.E.2
  • 52
    • 0035128557 scopus 로고    scopus 로고
    • Enhancement of amniotic cyclooxygenase type 2 activity in women with preterm delivery associated with twins or polyhydramnios
    • Leguizamon G, Smith J, Younis H, Nelson DM, Sadovsky Y. Enhancement of amniotic cyclooxygenase type 2 activity in women with preterm delivery associated with twins or polyhydramnios. Am J Obstet Gynecol 2001;184:117-122.
    • (2001) Am J Obstet Gynecol , vol.184 , pp. 117-122
    • Leguizamon, G.1    Smith, J.2    Younis, H.3    Nelson, D.M.4    Sadovsky, Y.5
  • 53
    • 20444462812 scopus 로고    scopus 로고
    • Placental expression ofenzymes regulating prostaglandin synthesis and degradation
    • Hirsch E, Goldstein M, Filipovich Y, Wang H. Placental expression ofenzymes regulating prostaglandin synthesis and degradation. Am J Obstet Gynecol 2005;192:1836-1842.
    • (2005) Am J Obstet Gynecol , vol.192 , pp. 1836-1842
    • Hirsch, E.1    Goldstein, M.2    Filipovich, Y.3    Wang, H.4
  • 55
    • 40549135313 scopus 로고    scopus 로고
    • Medroxyprogesterone acetate modulates the immune response in the uterus, cervix and placenta in a mouse model of preterm birth
    • Elovitz MA, Gonzalez J. Medroxyprogesterone acetate modulates the immune response in the uterus, cervix and placenta in a mouse model of preterm birth. J Matern Fetal Neonatal Med 2008;21:223-230.
    • (2008) J Matern Fetal Neonatal Med , vol.21 , pp. 223-230
    • Ma, E.1    Gonzalez, J.2
  • 56
    • 44449126598 scopus 로고    scopus 로고
    • Paternal race and preterm birth
    • Simhan HN, Krohn MA. Paternal race and preterm birth. Am J Obstet Gynecol 2008;198:644-646.
    • (2008) Am J Obstet Gynecol , vol.198 , pp. 644-646
    • Simhan, H.N.1    Krohn, MA.2
  • 57
    • 58149086262 scopus 로고    scopus 로고
    • The adaptor protein MyD88 is essential for e coli-induced preterm delivery in mice
    • Filipovich Y, Lu SJ, Akira S, Hirsch E. The adaptor protein MyD88 is essential for E coli-induced preterm delivery in mice. Am J Obstet Gynecol 2009;200:93-98.
    • (2009) Am J Obstet Gynecol , vol.200 , pp. 93-98
    • Filipovich, Y.1    Lu, S.J.2    Akira, S.3    Hirsch, E.4
  • 58
    • 62549154475 scopus 로고    scopus 로고
    • First-trimester cervical inflamma-tory milieu and subsequent early preterm birth
    • Simhan HN, Krohn MA. First-trimester cervical inflamma-tory milieu and subsequent early preterm birth. Am J Obstet Gynecol 2009;200:377-374.
    • (2009) Am J Obstet Gynecol , vol.200 , pp. 377-374
    • Simhan, H.N.1    Krohn, MA.2
  • 59
    • 0035196408 scopus 로고    scopus 로고
    • The role of thrombin in preterm parturition
    • Elovitz MA, Baron J, Phillippe M. The role of thrombin in preterm parturition. Am J Obstet Gynecol 2001;185:1059-1063.
    • (2001) Am J Obstet Gynecol , vol.185 , pp. 1059-1063
    • Ma, E.1    Baron, J.2    Phillippe, M.3
  • 63
    • 33646342782 scopus 로고    scopus 로고
    • Association of a maternal CD14-159 gene polymorphism with preterm premature rupture of membranes and sponta-neous preterm birth in multi-fetal pregnancies
    • Kalish RB, Vardhana S, Normand NJ, Gupta M, Witkin SS. Association of a maternal CD14-159 gene polymorphism with preterm premature rupture of membranes and sponta-neous preterm birth in multi-fetal pregnancies. J Reprod Immunol 2006;70:109-117.
    • (2006) J Reprod Immunol , vol.70 , pp. 109-117
    • Kalish, R.B.1    Vardhana, S.2    Normand, N.J.3    Gupta, M.4    Witkin, S.S.5
  • 64
    • 38449088343 scopus 로고    scopus 로고
    • Modulation ofmonocyte chemotactic protein-1 expression during lipopolysaccharide-induced preterm de-livery in the pregnant mouse
    • Diamond AK, Sweet LM, Oppenheimer KH, Bradley DF, Phillippe M. Modulation ofmonocyte chemotactic protein-1 expression during lipopolysaccharide-induced preterm de-livery in the pregnant mouse. Reprod Sci 2007;14:548-559.
    • (2007) Reprod Sci , vol.14 , pp. 548-559
    • Diamond, A.K.1    Sweet, L.M.2    Oppenheimer, K.H.3    Bradley, D.F.4    Phillippe, M.5
  • 65
    • 51649118406 scopus 로고    scopus 로고
    • Maternal and neonatal interleukin-1 receptor antagonist geno-type and pregnancy outcome in a population with a high rate of pre-termbirth
    • Chaves JH, Babayan A, Bezerra CM, Linhares IM, Witkin SS. Maternal and neonatal interleukin-1 receptor antagonist geno-type and pregnancy outcome in a population with a high rate of pre-termbirth. Am J Reprod Immunol 2008; 60:312-317.
    • (2008) Am J Reprod Immunol , vol.60 , pp. 312-317
    • Chaves, J.H.1    Babayan, A.2    Bezerra, C.M.3    Linhares, I.M.4    Witkin, S.S.5
  • 66
    • 38049174518 scopus 로고    scopus 로고
    • Primary, secondary, and tertiary interventions to reduce the morbidity and mortality ofpreterm birth
    • Iams JD, Romero R, Culhane JF, Goldenberg RL. Primary, secondary, and tertiary interventions to reduce the morbidity and mortality ofpreterm birth. Lancet 2008;371:164-175.
    • (2008) Lancet , vol.371 , pp. 164-175
    • Iams, J.D.1    Romero, R.2    Culhane, J.F.3    Goldenberg, R.L.4
  • 67
    • 57849126736 scopus 로고    scopus 로고
    • Insights into parturition biology from genetically altered mice
    • Ratajczak CK, Muglia LJ. Insights into parturition biology from genetically altered mice. Pediatr Res 2008;64:581-589.
    • (2008) Pediatr Res , vol.64 , pp. 581-589
    • Ratajczak, C.K.1    Muglia, L.J.2
  • 70
    • 67249152701 scopus 로고    scopus 로고
    • The correlation in birth timing between singleton and twin gestations in the same mother
    • Defranco EA, Chang JJ, Macones GA, Muglia LJ. The correlation in birth timing between singleton and twin gestations in the same mother. J Matern Fetal Neonatal Med 2009;22:106-110.
    • (2009) J Matern Fetal Neonatal Med , vol.22 , pp. 106-110
    • Defranco, E.A.1    Chang, J.J.2    MacOnes, G.A.3    Muglia, L.J.4
  • 74
    • 33845567710 scopus 로고    scopus 로고
    • The use ofhigh-dimensional biology (genomics transcriptomics proteomics and metabolomics) to understand the preterm parturition syndrome
    • Romero R, Espinoza J, Gotsch F, Kusanovic JP Friel LA Erez O Mazaki-Tovi S Than NG Hassan S Tromp G. The use ofhigh-dimensional biology (genomics transcriptomics proteomics and metabolomics) to understand the preterm parturition syndrome. BJOG 2006; 113: (suppl 3) 118-135.
    • (2006) BJOG , vol.113 , Issue.SUPPL. 3 , pp. 118-135
    • Romero, R.1    Espinoza, J.2    Kusanovic, G.F.3    Friel, L.A.4    Erez, O.5    Mazaki-Tovi, S.6    Than, N.G.7    Hassan, S.8    Tromp, G.9
  • 75
    • 33746676270 scopus 로고    scopus 로고
    • High-dimensional biology in obste-trics and gynecology: Functional genomics in microarray studies
    • Romero R, Tromp G. High-dimensional biology in obste-trics and gynecology: functional genomics in microarray studies. Am J Obstet Gynecol 2006;195:360-363.
    • (2006) Am J Obstet Gynecol , vol.195 , pp. 360-363
    • Romero, R.1    Tromp, G.2
  • 76
    • 0033951108 scopus 로고    scopus 로고
    • Designer science and the "omic" revolution
    • Evans GA. Designer science and the "omic" revolution. Nat Biotechnol 2000;18:127.
    • (2000) Nat Biotechnol , vol.18 , pp. 127
    • Evans, G.A.1
  • 77
    • 0037974525 scopus 로고    scopus 로고
    • Application of microarray technol-ogy in environmental and comparative physiology
    • Gracey AY, Cossins AR. Application of microarray technol-ogy in environmental and comparative physiology. Annu Rev Physiol 2003;65:231-259.
    • (2003) Annu Rev Physiol , vol.65 , pp. 231-259
    • Gracey, A.Y.1    Cossins, A.R.2
  • 78
    • 4444371602 scopus 로고    scopus 로고
    • Towards sound epistemo-logical foundations of statistical methods for high-dimen-sional biology
    • Mehta T, Tanik M, Allison DB. Towards sound epistemo-logical foundations of statistical methods for high-dimen-sional biology. Nat Genet 2004;36:943-947.
    • (2004) Nat Genet , vol.36 , pp. 943-947
    • Mehta, T.1    Tanik, M.2    Allison, D.B.3
  • 79
    • 0032561082 scopus 로고    scopus 로고
    • Fishing expeditions
    • Weinstein JN. Fishing expeditions. Science 1998;282:628-629.
    • (1998) Science , vol.282 , pp. 628-629
    • Weinstein, J.N.1
  • 80
    • 0036667384 scopus 로고    scopus 로고
    • 'Omic' and hypothesis-driven research in the molecular pharmacology of cancer
    • Weinstein JN. 'Omic' and hypothesis-driven research in the molecular pharmacology of cancer. Curr Opin Pharmacol 2002;2:361-365.
    • (2002) Curr Opin Pharmacol , vol.2 , pp. 361-365
    • Weinstein, J.N.1
  • 81
    • 0035860972 scopus 로고    scopus 로고
    • Genetics moves into the medical mainstream
    • Collins FS, Guttmacher AE. Genetics moves into the medical mainstream. JAMA 2001;286:2322-2324.
    • (2001) JAMA , vol.286 , pp. 2322-2324
    • Collins, F.S.1    Guttmacher, A.E.2
  • 82
    • 0035169803 scopus 로고    scopus 로고
    • The Human Genome Project. Revealing the shared inheritance of all humankind
    • Collins FS, Mansoura MK. The Human Genome Project. Revealing the shared inheritance of all humankind. Cancer 2001;91:221-225.
    • (2001) Cancer , vol.91 , pp. 221-225
    • Collins, F.S.1    Mansoura, M.K.2
  • 83
    • 0035575568 scopus 로고    scopus 로고
    • Personalized medicine: Revolu-tionizing drug discovery and patient care
    • Ginsburg GS, McCarthy JJ. Personalized medicine: revolu-tionizing drug discovery and patient care. Trends Biotechnol 2001;19:491-496.
    • (2001) Trends Biotechnol , vol.19 , pp. 491-496
    • Ginsburg, G.S.1    McCarthy, J.J.2
  • 84
    • 0035861038 scopus 로고    scopus 로고
    • The anatomy of the human genome: A neo-Vesalian basis for medicine in the 21st century
    • McKusick VA. The anatomy of the human genome: a neo-Vesalian basis for medicine in the 21st century. JAMA 2001;286:2289-2295.
    • (2001) JAMA , vol.286 , pp. 2289-2295
    • McKusick, V.A.1
  • 85
    • 0035861004 scopus 로고    scopus 로고
    • Implications ofthe human genome for understanding human biology and medicine
    • Subramanian G, Adams MD, Venter JC, Broder S. Implications ofthe human genome for understanding human biology and medicine. JAMA 2001;286:2296-2307.
    • (2001) JAMA , vol.286 , pp. 2296-2307
    • Subramanian, G.1    Adams, M.D.2    Venter, J.C.3    Broder, S.4
  • 87
    • 0028806048 scopus 로고
    • Quantitative monitoring of gene expression patterns with a complemen-tary DNA microarray
    • Schena M, Shalon D, Davis RW, Brown PO. Quantitative monitoring of gene expression patterns with a complemen-tary DNA microarray. Science 1995;270:467-470.
    • (1995) Science , vol.270 , pp. 467-470
    • Schena, M.1    Shalon, D.2    Davis, R.W.3    Brown, P.O.4
  • 91
    • 0141653274 scopus 로고    scopus 로고
    • Global analyses of cellular lipidomes directly from crude extracts of biological samples by ESI mass spectrometry: A bridge to lipidomics
    • Han X, Gross RW. Global analyses of cellular lipidomes directly from crude extracts of biological samples by ESI mass spectrometry: a bridge to lipidomics. J Lipid Res 2003;44:1071-1079.
    • (2003) J Lipid Res , vol.44 , pp. 1071-1079
    • Han, X.1    Gross, R.W.2
  • 93
    • 22144478635 scopus 로고    scopus 로고
    • The emerging field oflipidomics
    • Wenk MR. The emerging field oflipidomics. Nat Rev Drug Discov 2005;4:594-610.
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 594-610
    • Wenk, M.R.1
  • 95
    • 29244475955 scopus 로고    scopus 로고
    • Metabolomic analysis of molecular species of phospholipids from normotensive and preeclamptic human placenta electrospray ionization mass spectrometry
    • Jain S, Jayasimhulu K, Clark JF. Metabolomic analysis of molecular species of phospholipids from normotensive and preeclamptic human placenta electrospray ionization mass spectrometry. Front Biosci 2004;9:3167-3175.
    • (2004) Front Biosci , vol.9 , pp. 3167-3175
    • Jain, S.1    Jayasimhulu, K.2    Clark, J.F.3
  • 96
    • 33646380353 scopus 로고    scopus 로고
    • A bioinformatician's view of the metabolome
    • Nobeli I, Thornton JM. A bioinformatician's view of the metabolome. Bioessays 2006;28:534-545.
    • (2006) Bioessays , vol.28 , pp. 534-545
    • Nobeli, I.1    Thornton, J.M.2
  • 98
    • 30544454201 scopus 로고    scopus 로고
    • Metabolomics reviewed: A new "omics" plat-form technology for systems biology and implications for natural products research
    • Rochfort S. Metabolomics reviewed: a new "omics" plat-form technology for systems biology and implications for natural products research. J Nat Prod 2005;68:1813-1820.
    • (2005) J Nat Prod , vol.68 , pp. 1813-1820
    • Rochfort, S.1
  • 101
    • 29144497972 scopus 로고    scopus 로고
    • Proteomic analysis using protein chips to detect biomarkers in cervical and amniotic fluid in women with intra-amniotic inflammation
    • Ruetschi U, Rosen A, Karlsson G, Zetterberg H, Rymo L, Hagberg H, Jacobsson B. Proteomic analysis using protein chips to detect biomarkers in cervical and amniotic fluid in women with intra-amniotic inflammation. J Proteome Res 2005;4:2236-2242.
    • (2005) J Proteome Res , vol.4 , pp. 2236-2242
    • Ruetschi, U.1    Rosen, A.2    Karlsson, G.3    Zetterberg, H.4    Rymo, L.5    Hagberg, H.6    Jacobsson, B.7
  • 102
    • 64249096042 scopus 로고    scopus 로고
    • Predictive value ofcombined amniotic fluid proteomic biomarkers and interleukin-6 in preterm labor with intact membranes
    • Cobo T, Palacio M, Navarro-Sastre A, Ribes A, Bosch J, Filella X, Gratacos E. Predictive value ofcombined amniotic fluid proteomic biomarkers and interleukin-6 in preterm labor with intact membranes. Am J Obstet Gynecol 2009;200:499-496.
    • (2009) Am J Obstet Gynecol , vol.200 , pp. 499-496
    • Cobo, T.1    Palacio, M.2    Navarro-Sastre, A.3    Ribes, A.4    Bosch, J.5    Filella, X.6    Gratacos, E.7
  • 103
    • 66749133422 scopus 로고    scopus 로고
    • Identification and quantification of preterm birth biomarkers in human cervicovaginal fluid by liquid chromatography/tandem mass spectrometry
    • Shah SJ, Yu KH, Sangar V, Parry SI, Blair IA. Identification and quantification of preterm birth biomarkers in human cervicovaginal fluid by liquid chromatography/tandem mass spectrometry. J Proteome Res 2009;8:2407-2417.
    • (2009) J Proteome Res , vol.8 , pp. 2407-2417
    • Shah, S.J.1    Yu, K.H.2    Sangar, V.3    Parry, S.I.4    Blair, I.A.5
  • 104
    • 57449096548 scopus 로고    scopus 로고
    • An overview of proteomic and metabolomic technologies and their applica-tion to pregnancy research
    • Horgan RP, Clancy OH, Myers JE, Baker PN. An overview of proteomic and metabolomic technologies and their applica-tion to pregnancy research. BJOG 2009;116:173-181.
    • (2009) BJOG , vol.116 , pp. 173-181
    • Horgan, R.P.1    Clancy, O.H.2    Myers, J.E.3    Baker, P.N.4
  • 112
    • 0026048347 scopus 로고
    • Amniotic fluid white blood cell count: A rapid and simple test to diagnose microbial invasion of the amniotic cavity and predict preterm delivery
    • Romero R, Quintero R, Nores J, Avila C, Mazor M, Hanaoka S, Hagay Z, Merchant L, Hobbins JC. Amniotic fluid white blood cell count: a rapid and simple test to diagnose microbial invasion of the amniotic cavity and predict preterm delivery. Am J Obstet Gynecol 1991; 165:821-830.
    • (1991) Am J Obstet Gynecol , vol.165 , pp. 821-830
    • Romero, R.1    Quintero, R.2    Nores, J.3    Avila, C.4    Mazor, M.5    Hanaoka, S.6    Hagay, Z.7    Merchant, L.8    Hobbins, J.C.9
  • 116
    • 10844225652 scopus 로고    scopus 로고
    • Development of a simplified method for the simultaneous determination ofretinol, alpha-tocopherol, and beta-carotene in serum by liquid chromatography-tandem mass spectrometry with atmospheric pressure chemical ionization
    • Andreoli R, Manini P, Poli D, Bergamaschi E, Mutti A, Niessen WM. Development of a simplified method for the simultaneous determination ofretinol, alpha-tocopherol, and beta-carotene in serum by liquid chromatography-tandem mass spectrometry with atmospheric pressure chemical ionization. Anal Bioanal Chem 2004;378:987-994.
    • (2004) Anal Bioanal Chem , vol.378 , pp. 987-994
    • Andreoli, R.1    Manini, P.2    Poli, D.3    Bergamaschi, E.4    Mutti, A.5    Niessen, W.M.6
  • 117
    • 0015212723 scopus 로고
    • Trimethylsilylation of amino acids derivatization and chromatography
    • Gehrke CW, Leimer K. Trimethylsilylation of amino acids derivatization and chromatography. J Chromatogr 1971;57: 219-238.
    • (1971) J Chromatogr , vol.57 , pp. 219-238
    • Gehrke, C.W.1    Leimer, K.2
  • 118
    • 68849083050 scopus 로고    scopus 로고
    • Integrated, nontargeted ultrahigh performance liquid chro-matography/ electrospray ionization tandem mass spectro-metry platform for the identification and relative quantification of the small-molecule complement ofbiologi-cal systems
    • Evans AM, Dehaven CD, Barrett T, Mitchell M, Milgram E. Integrated, nontargeted ultrahigh performance liquid chro-matography/electrospray ionization tandem mass spectro-metry platform for the identification and relative quantification of the small-molecule complement ofbiologi-cal systems. Anal Chem 2009;81:6656-6667.
    • (2009) Anal Chem , vol.81 , pp. 6656-6667
    • Evans, A.M.1    Dehaven, C.D.2    Barrett, T.3    Mitchell, M.4    Milgram, E.5
  • 119
    • 0345040873 scopus 로고    scopus 로고
    • Classication and regression by random forest
    • Liaw A, Wiener M. Classication and regression by random forest. R News 2002;2:18-22.
    • (2002) R News , vol.2 , pp. 18-22
    • Liaw, A.1    Wiener, M.2
  • 120
    • 0030190032 scopus 로고
    • Technical note: Some properties of splitting criteria
    • Breiman L. Technical note: some properties of splitting criteria. Mach Learn 1966;24:41-47.
    • (1966) Mach Learn , vol.24 , pp. 41-47
    • Breiman, L.1
  • 122
  • 125
    • 0031726988 scopus 로고    scopus 로고
    • An increase in fetal plasma cortisol but not dehydroepiandrosterone sulfate is followed by the onset of preterm labor in patients with preterm premature rupture of the membranes
    • Yoon BH, Romero R, Jun JK, Maymon E, Gomez R, Mazor M, Park JS. An increase in fetal plasma cortisol but not dehydroepiandrosterone sulfate is followed by the onset of preterm labor in patients with preterm premature rupture of the membranes. Am J Obstet Gynecol 1998;179:1107-1114.
    • (1998) Am J Obstet Gynecol , vol.179 , pp. 1107-1114
    • Yoon, B.H.1    Romero, R.2    Jun, J.K.3    Maymon, E.4    Gomez, R.5    Mazor, M.6    Park, J.S.7
  • 126
    • 0034037785 scopus 로고    scopus 로고
    • Fetal exposure to an intra-amniotic inflammation and the development of cerebral palsy at the age of three years
    • Yoon BH, Romero R, Park JS, Kim CJ, Kim SH, Choi JH, Han TR. Fetal exposure to an intra-amniotic inflammation and the development of cerebral palsy at the age of three years. Am J Obstet Gynecol 2000;182:675-681.
    • (2000) Am J Obstet Gynecol , vol.182 , pp. 675-681
    • Yoon, B.H.1    Romero, R.2    Park, J.S.3    Kim, C.J.4    Kim, S.H.5    Choi, J.H.6    Han, T.R.7
  • 127
    • 0026441001 scopus 로고
    • Early metabolic effects of sepsis in the preterm infant: Lactic acidosis and increased glucose requirement
    • Fitzgerald MJ, Goto M, Myers TF, Zeller WP. Early metabolic effects of sepsis in the preterm infant: lactic acidosis and increased glucose requirement. J Pediatr 1992;121:951-955.
    • (1992) J Pediatr , vol.121 , pp. 951-955
    • Fitzgerald, M.J.1    Goto, M.2    Myers, T.F.3    Zeller, W.P.4
  • 128
    • 0014877831 scopus 로고
    • Hypoglycemia in neonatal sepsis
    • Yeung CY. Hypoglycemia in neonatal sepsis. J Pediatr 1970;77:812-817.
    • (1970) J Pediatr , vol.77 , pp. 812-817
    • Yeung, C.Y.1
  • 129
    • 0015598573 scopus 로고
    • Glucose disappearance rate in neonatal infection
    • Yeung CY, Lee VW, Yeung CM. Glucose disappearance rate in neonatal infection. J Pediatr 1973;82:486-489.
    • (1973) J Pediatr , vol.82 , pp. 486-489
    • Yeung, C.Y.1    Lee, V.W.2    Yeung, C.M.3
  • 130
    • 0019492006 scopus 로고
    • Rapid glucosedisappearance in infantswithinfection
    • Leake RD, Fiser RH Jr, Oh W. Rapid glucosedisappearance in infantswithinfection. Clin Pediatr (Phila) 1981;20:397-401.
    • (1981) Clin Pediatr (Phila) , vol.20 , pp. 397-401
    • Leake, R.D.1    Fiser Jr., R.H.2    Oh, W.3
  • 131
  • 133
    • 0036822310 scopus 로고    scopus 로고
    • Transport and metabolism of amino acids in placenta
    • Regnault TR, de Vrijer B, Battaglia FC. Transport and metabolism of amino acids in placenta. Endocrine 2002;19:23-41.
    • (2002) Endocrine , vol.19 , pp. 23-41
    • Regnault, T.R.1    De Vrijer, B.2    Battaglia, F.C.3
  • 134
    • 0024449534 scopus 로고
    • Infection and labor. V. Prevalence, microbiology, and clinical significance of intraamniotic infection in women with preterm labor and intact membranes
    • Romero R, Sirtori M, Oyarzun E, Avila C, Mazor M, Callahan R, Sabo V, Athanassiadis AP, Hobbins JC. Infection and labor. V. Prevalence, microbiology, and clinical significance of intraamniotic infection in women with preterm labor and intact membranes. Am J Obstet Gynecol 1989;161:817-824.
    • (1989) Am J Obstet Gynecol , vol.161 , pp. 817-824
    • Romero, R.1    Sirtori, M.2    Oyarzun, E.3    Avila, C.4    Mazor, M.5    Callahan, R.6    Sabo, V.7    Athanassiadis, A.P.8    Hobbins, J.C.9
  • 135
    • 0025369863 scopus 로고
    • Amniotic fluid interleukin 6 in preterm labor. Association with infection
    • Romero R, Avila C, Santhanam U, Sehgal PB. Amniotic fluid interleukin 6 in preterm labor. Association with infection. J Clin Invest 1990;85:1392-1400.
    • (1990) J Clin Invest , vol.85 , pp. 1392-1400
    • Romero, R.1    Avila, C.2    Santhanam, U.3    Sehgal, P.B.4
  • 136
    • 0027443961 scopus 로고
    • A comparative study ofthe diagnostic performance ofamniotic fluid glucose, white blood cell count, interleukin-6, and gram stain in the detection of microbial invasion in patients with preterm premature rupture ofmembranes
    • Romero R, Yoon BH, Mazor M, Gomez R, Gonzalez R, Diamond MP, Baumann P, Araneda H, Kenney JS, Cotton DB, et al. A comparative study ofthe diagnostic performance ofamniotic fluid glucose, white blood cell count, interleukin-6, and gram stain in the detection of microbial invasion in patients with preterm premature rupture ofmembranes. Am J Obstet Gynecol 1993;169:839-851.
    • (1993) Am J Obstet Gynecol , vol.169 , pp. 839-851
    • Romero, R.1    Yoon, B.H.2    Mazor, M.3    Gomez, R.4    Gonzalez, R.5    Diamond, M.P.6    Baumann, P.7    Araneda, H.8    Kenney, J.S.9    Cotton, D.B.10
  • 137
    • 0028566833 scopus 로고
    • The value ofamniotic fluid interleukin-6, white blood cell count, and gram stain in the diagnosis ofmicrobial invasion of the amniotic cavity in patients at term
    • Gomez R, Romero R, Galasso M, Behnke E, Insunza A, Cotton DB. The value ofamniotic fluid interleukin-6, white blood cell count, and gram stain in the diagnosis ofmicrobial invasion of the amniotic cavity in patients at term. Am J Reprod Immunol 1994;32:200-210.
    • (1994) Am J Reprod Immunol , vol.32 , pp. 200-210
    • Gomez, R.1    Romero, R.2    Galasso, M.3    Behnke, E.4    Insunza, A.5    Cotton, D.B.6
  • 138
    • 77049260357 scopus 로고
    • Reduced concentra-tion ofcerebrospinal fluid glucose in tuberculous meningitis; Experimental studies
    • Wasz-Hockert O, Brander E, Paatela M. Reduced concentra-tion ofcerebrospinal fluid glucose in tuberculous meningitis; experimental studies. Ann Paediatr Fenn 1956;2:320-326.
    • (1956) Ann Paediatr Fenn , vol.2 , pp. 320-326
    • Wasz-Hockert, O.1    Brander, E.2    Paatela, M.3
  • 139
    • 68649098431 scopus 로고
    • Hypoglycorrhachia (low cerebrospinal-fluid sugar) in diffuse meningeal neoplasm
    • Levinsky WJ. Hypoglycorrhachia (low cerebrospinal-fluid sugar) in diffuse meningeal neoplasm. N Engl J Med 1963;268:198-199.
    • (1963) N Engl J Med , vol.268 , pp. 198-199
    • Levinsky, W.J.1
  • 140
    • 0018270356 scopus 로고
    • Synovial fluid glucose
    • Owen DS. Synovial fluid glucose. JAMA 1978;239:193.
    • (1978) JAMA , vol.239 , pp. 193
    • Owen, D.S.1
  • 141
    • 0023948283 scopus 로고
    • Identification of a galactose-binding lectin on Fusobacterium nucleatum FN-2
    • Murray PA, Kern DG, Winkler JR. Identification of a galactose-binding lectin on Fusobacterium nucleatum FN-2. Infect Immunol 1988;56:1314-1319.
    • (1988) Infect Immunol , vol.56 , pp. 1314-1319
    • Murray, P.A.1    Kern, D.G.2    Winkler, J.R.3
  • 142
    • 0021835785 scopus 로고
    • Detection of lipoglycans in ureaplasmas
    • Smith PF. Detection of lipoglycans in ureaplasmas. JBacteriol 1985;162:611-614.
    • (1985) JBacteriol , vol.162 , pp. 611-614
    • Smith, P.F.1
  • 143
    • 30344454215 scopus 로고    scopus 로고
    • Oxidant release is dramatically increased by elevated glucose concentrations in neutrophils from pregnant women
    • Petty HR, Kindzelskii AL, Chaiworapongsa T, Petty AR, Romero R. Oxidant release is dramatically increased by elevated glucose concentrations in neutrophils from pregnant women. J Matern Fetal Neonatal Med 2005;18:397-404.
    • (2005) J Matern Fetal Neonatal Med , vol.18 , pp. 397-404
    • Petty, H.R.1    Kindzelskii, A.L.2    Chaiworapongsa, T.3    Petty, A.R.4    Romero, R.5
  • 144
    • 0029163078 scopus 로고
    • Structure and function of DNA methyltrans-ferases
    • Cheng X. Structure and function of DNA methyltrans-ferases. Annu Rev Biophys Biomol Struct 1995;24:293-318.
    • (1995) Annu Rev Biophys Biomol Struct , vol.24 , pp. 293-318
    • Cheng, X.1
  • 145
    • 0021689820 scopus 로고
    • DNA adenine methyla-tion of GATC sequences appeared recently in the Escherichia coli lineage
    • Barbeyron T, Kean K, Forterre P. DNA adenine methyla-tion of GATC sequences appeared recently in the Escherichia coli lineage. J Bacteriol 1984;160:586-590.
    • (1984) J Bacteriol , vol.160 , pp. 586-590
    • Barbeyron, T.1    Kean, K.2    Forterre, P.3
  • 146
    • 33646008874 scopus 로고    scopus 로고
    • N6-methyl-adenine: An epigenetic signal for DNA-protein interactions
    • Wion D, Casadesus J. N6-methyl-adenine: an epigenetic signal for DNA-protein interactions. Nat Rev Microbiol 2006;4:183-192.
    • (2006) Nat Rev Microbiol , vol.4 , pp. 183-192
    • Wion, D.1    Casadesus, J.2
  • 147
    • 27744482480 scopus 로고    scopus 로고
    • Simultaneous high performance liquid chromatographic separation of purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism
    • Tavazzi B, Lazzarino G, Leone P, Amorini AM, Bellia F, Janson CG, Di P, Ceccarelli L, Donzelli S, Francis JS, et al. Simultaneous high performance liquid chromatographic separation of purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism. Clin Biochem 2005;38:997-1008.
    • (2005) Clin Biochem , vol.38 , pp. 997-1008
    • Tavazzi, B.1    Lazzarino, G.2    Leone, P.3    Amorini, A.M.4    Bellia, F.5    Janson, C.G.6    Di Ceccarelli P, L.7    Donzelli, S.8    Francis, J.S.9
  • 148
    • 2442643045 scopus 로고    scopus 로고
    • Structural phases of hexamethylenetetramine-pimelic acid (1/1): A unified de-scription based on a stacking model
    • Gardon M, Pinheiro CB, Chapuis G. Structural phases of hexamethylenetetramine-pimelic acid (1/1): a unified de-scription based on a stacking model. Acta Crystallogr B 2003;59:527-536.
    • (2003) Acta Crystallogr B , vol.59 , pp. 527-536
    • Gardon, M.1    Pinheiro, C.B.2    Chapuis, G.3
  • 149
    • 0342651790 scopus 로고
    • The stereoisomers of alpha epsilon-diaminopimelic acid. II. Their distribution in the bacterial orderActinomycetales and in certain Eubacteriales
    • Hoare DS, Work E. The stereoisomers of alpha epsilon-diaminopimelic acid. II. Their distribution in the bacterial orderActinomycetales and in certain Eubacteriales. Biochem J 1957;65:441-447.
    • (1957) Biochem J , vol.65 , pp. 441-447
    • Hoare, D.S.1    Work, E.2
  • 151
    • 0030087892 scopus 로고    scopus 로고
    • The DAP pathway to lysine as a target for antimicrobial agents
    • Cox RJ. The DAP pathway to lysine as a target for antimicrobial agents. Nat Prod Rep 1996;13:29-43.
    • (1996) Nat Prod Rep , vol.13 , pp. 29-43
    • Cox, R.J.1
  • 152
    • 0032831101 scopus 로고    scopus 로고
    • Structure/function studies on enzymes in the diaminopimelate pathway of bacterial cell wall biosynthesis
    • Born TL, Blanchard JS. Structure/function studies on enzymes in the diaminopimelate pathway of bacterial cell wall biosynthesis. Curr Opin Chem Biol 1999;3:607-613.
    • (1999) Curr Opin Chem Biol , vol.3 , pp. 607-613
    • Born, T.L.1    Blanchard, J.S.2
  • 154
    • 0015462556 scopus 로고
    • Peptidoglycan types ofbacterial cell walls and their taxonomic implications
    • Schleifer KH, Kandler O. Peptidoglycan types ofbacterial cell walls and their taxonomic implications. Bacteriol Rev 1972;36:407-477.
    • (1972) Bacteriol Rev , vol.36 , pp. 407-477
    • Schleifer, K.H.1    Kandler, O.2
  • 155
    • 70350634024 scopus 로고    scopus 로고
    • Amniotic fluid prostaglandin F2 increases even in sterile amniotic fluid and is an independent predictor ofimpending delivery in preterm premature rupture of membranes
    • Lee SE, Park IS, Romero R, Yoon BH. Amniotic fluid prostaglandin F2 increases even in sterile amniotic fluid and is an independent predictor ofimpending delivery in preterm premature rupture of membranes. J Matern Fetal Neonatal Med 2009;22:880-886.
    • (2009) J Matern Fetal Neonatal Med , vol.22 , pp. 880-886
    • Lee, S.E.1    Park, I.S.2    Romero, R.3    Yoon, B.H.4
  • 156
    • 23044504439 scopus 로고    scopus 로고
    • Identification of 9alpha,11beta-prostaglandin F2 in human amniotic fluid and characterization of its production by human gestational tissues
    • Mitchell MD, Chang MC, Chaiworapongsa T, Lan HY, Helliwell RJ, Romero R, Sato TA. Identification of 9alpha,11beta-prostaglandin F2 in human amniotic fluid and characterization of its production by human gestational tissues. J Clin Endocrinol Metab 2005;90:4244-4248.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 4244-4248
    • Mitchell, M.D.1    Chang, M.C.2    Chaiworapongsa, T.3    Lan, H.Y.4    Helliwell, R.J.5    Romero, R.6    Sato, T.A.7
  • 158
    • 0027232277 scopus 로고
    • The relationship between spontaneous rupture of membranes, labor, and microbial invasion of the amniotic cavity and amniotic fluid concentrations of prostaglandins and throm-boxane B2 in term pregnancy
    • Romero R, Baumann P, Gomez R, Salafia C, Rittenhouse L, Barberio D, Behnke E, Cotton DB, Mitchell MD. The relationship between spontaneous rupture of membranes, labor, and microbial invasion of the amniotic cavity and amniotic fluid concentrations of prostaglandins and throm-boxane B2 in term pregnancy. Am J Obstet Gynecol 1993;168:1654-1664.
    • (1993) Am J Obstet Gynecol , vol.168 , pp. 1654-1664
    • Romero, R.1    Baumann, P.2    Gomez, R.3    Salafia, C.4    Rittenhouse, L.5    Barberio, D.6    Behnke, E.7    Cotton, D.B.8    Mitchell, M.D.9
  • 159
    • 0024521512 scopus 로고
    • Amniotic fluid concentrations of prostaglandin F2 alpha 13,14-dihydro-15-keto-prostaglan-din F2 alpha (PGFM) and 11-deoxy-13,14-dihydro- 15-keto-11, 16-cyclo-prostaglandin E2 (PGEM-LL) in preterm labor
    • Romero R, Wu YK, Sirtori M, Oyarzun E, Mazor M, Hobbins JC, Mitchell MD. Amniotic fluid concentrations of prostaglandin F2 alpha, 13,14-dihydro-15-keto- prostaglan-din F2 alpha (PGFM) and 11-deoxy-13,14-dihydro-15-keto-11, 16-cyclo-prostaglandin E2 (PGEM-LL) in preterm labor. Prostaglandins 1989;37:149-161.
    • (1989) Prostaglandins , vol.37 , pp. 149-161
    • Romero, R.1    Wu, Y.K.2    Sirtori, M.3    Oyarzun, E.4    Mazor, M.5    Hobbins, J.C.6    Mitchell, M.D.7
  • 166
    • 0023473575 scopus 로고
    • Increased concentrations ofarachidonic acid lipoxygenase metabolites in amniotic fluid during parturi-tion
    • Romero R, Emamian M, Wan M, Grzyboski C, Hobbins JC, Mitchell MD. Increased concentrations ofarachidonic acid lipoxygenase metabolites in amniotic fluid during parturi-tion. Obstet Gynecol 1987;70:849-851.
    • (1987) Obstet Gynecol , vol.70 , pp. 849-851
    • Romero, R.1    Emamian, M.2    Wan, M.3    Grzyboski, C.4    Hobbins, J.C.5    Mitchell, M.D.6
  • 167
    • 7044226549 scopus 로고    scopus 로고
    • Genome-wide expression profiling of fetal membranes reveals a deficient expression of proteinase inhibitor 3 in premature rupture of membranes
    • Tromp G, Kuivaniemi H, Romero R, Chaiworapongsa T, Kim YM, Kim MR, Maymon E, Edwin S. Genome-wide expression profiling of fetal membranes reveals a deficient expression of proteinase inhibitor 3 in premature rupture of membranes. Am J Obstet Gynecol 2004;191:1331-1338.
    • (2004) Am J Obstet Gynecol , vol.191 , pp. 1331-1338
    • Tromp, G.1    Kuivaniemi, H.2    Romero, R.3    Chaiworapongsa, T.4    Kim, Y.M.5    Kim, M.R.6    Maymon, E.7    Edwin, S.8
  • 168
    • 58149490683 scopus 로고    scopus 로고
    • Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma
    • Chiu RW, Chan KC, Gao Y, Lau VY, Zheng W, Leung TY, Foo CH, Xie B, Tsui NB, Lun FM, et al. Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma. Proc Natl Acad Sci USA 2008;105:20458-20463.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 20458-20463
    • Chiu, R.W.1    Chan, K.C.2    Gao, Y.3    Lau, V.Y.4    Zheng, W.5    Leung, T.Y.6    Ch, F.7    Xie, B.8    Tsui, N.B.9    Lun, F.M.10
  • 169
    • 34548008368 scopus 로고    scopus 로고
    • Functional genomics of the pregnant uterus: From expectations to reality, a compilation of studies in the myometrium
    • Breuiller-Fouche M, Charpigny G, Germain G. Functional genomics of the pregnant uterus: from expectations to reality, a compilation of studies in the myometrium. BMC Pregn Childbirth 2007;7 (Suppl 1):S4.
    • (2007) BMC Pregn Childbirth , vol.7 , Issue.SUPPL. 1
    • Breuiller-Fouche, M.1    Charpigny, G.2    Germain, G.3
  • 170
    • 33847206108 scopus 로고    scopus 로고
    • Genomics for health in preconception and prenatal periods
    • Dolan S, Biermann J, Damus K. Genomics for health in preconception and prenatal periods. J Nurs Scholarsh 2007;39:4-9.
    • (2007) J Nurs Scholarsh , vol.39 , pp. 4-9
    • Dolan, S.1    Biermann, J.2    Damus, K.3
  • 171
    • 21744443814 scopus 로고    scopus 로고
    • Genomics: New technology for obstetrics
    • Wilson RD. Genomics: new technology for obstetrics. J Obstet Gynaecol Can 2005;27:63-75.
    • (2005) J Obstet Gynaecol Can , vol.27 , pp. 63-75
    • Wilson, R.D.1
  • 173
    • 57149116919 scopus 로고    scopus 로고
    • The clinical content of preconception care: Genetics and genomics
    • Solomon BD, Jack BW, Feero WG. The clinical content of preconception care: genetics and genomics. Am J Obstet Gynecol 2008;199:S340-S344.
    • (2008) Am J Obstet Gynecol , vol.199
    • Solomon, B.D.1    Jack, B.W.2    Feero, W.G.3
  • 175
    • 42349091015 scopus 로고    scopus 로고
    • Genomic evolution ofthe placenta using co-option and duplication and divergence
    • Knox K, Baker JC. Genomic evolution ofthe placenta using co-option and duplication and divergence. Genome Res 2008;18:695-705.
    • (2008) Genome Res , vol.18 , pp. 695-705
    • Knox, K.1    Baker, J.C.2
  • 176
    • 40549121961 scopus 로고    scopus 로고
    • Whole-genome microarray and targeted analysis of angiogenesis-regulating gene expression (ENG, FLT1, VEGF, PlGF) in placentas from pre-eclamptic and small-for-gestational-age pregnancies
    • Toft JH, Lian IA, Tarca AL, Erez O, Espinoza J, Eide IP, Bjorge L, Draghici S, Romero R, Austgulen R. Whole-genome microarray and targeted analysis of angiogenesis-regulating gene expression (ENG, FLT1, VEGF, PlGF) in placentas from pre-eclamptic and small-for-gestational-age pregnancies. J Matern Fetal Neonatal Med 2008;21:267-273.
    • (2008) J Matern Fetal Neonatal Med , vol.21 , pp. 267-273
    • Toft, J.H.1    Lian, I.A.2    Tarca, A.L.3    Erez, O.4    Espinoza, J.5    Eide, I.P.6    Bjorge, L.7    Draghici, S.8    Romero, R.9    Austgulen, R.10
  • 177
    • 35948962821 scopus 로고    scopus 로고
    • Ahierarchical analysis of transcriptome alterations in intrauterine growth restriction (IUGR) reveals common pathophysiological pathways in mammals
    • Buffat C, Mondon F, Rigourd V, Boubred F, Bessieres B, Fayol L, Feuerstein JM, Gamerre M, Jammes H, Rebourcet R, et al. Ahierarchical analysis of transcriptome alterations in intrauterine growth restriction (IUGR) reveals common pathophysiological pathways in mammals. J Pathol 2007; 213:337-346.
    • (2007) J Pathol , vol.213 , pp. 337-346
    • Buffat, C.1    Mondon, F.2    Rigourd, V.3    Boubred, F.4    Bessieres, B.5    Fayol, L.6    Feuerstein, J.M.7    Gamerre, M.8    Jammes, H.9    Rebourcet, R.10
  • 179
    • 34250852221 scopus 로고    scopus 로고
    • Genome-wide expression analysis of placental malaria reveals features of lymphoid neogenesis during chronic infection
    • Muehlenbachs A, Fried M, Lachowitzer J, Mutabingwa TK, Duffy PE. Genome-wide expression analysis of placental malaria reveals features of lymphoid neogenesis during chronic infection. J Immunol 2007;179:557-565.
    • (2007) J Immunol , vol.179 , pp. 557-565
    • Muehlenbachs, A.1    Fried, M.2    Lachowitzer, J.3    Mutabingwa, T.K.4    Duffy, P.E.5
  • 180
    • 38749148847 scopus 로고    scopus 로고
    • Processes regulating cervical ripening differ from cervical dilation and postpartum repair: Insights from gene expression studies
    • Timmons BC, Mahendroo M. Processes regulating cervical ripening differ from cervical dilation and postpartum repair: insights from gene expression studies. Reprod Sci 2007;14:53-62.
    • (2007) Reprod Sci , vol.14 , pp. 53-62
    • Timmons, B.C.1    Mahendroo, M.2
  • 181
    • 35348861286 scopus 로고    scopus 로고
    • Functional network analysis of the transcriptomes of mesenchymal stem cells derived from amniotic fluid, amniotic membrane, cord blood, and bone marrow
    • Tsai MS, Hwang SM, Chen KD, Lee YS, Hsu LW, Chang YJ, Wang CN, Peng HH, Chang YL, Chao AS, et al. Functional network analysis of the transcriptomes of mesenchymal stem cells derived from amniotic fluid, amniotic membrane, cord blood, and bone marrow. Stem Cells 2007;25:2511-2523.
    • (2007) Stem Cells , vol.25 , pp. 2511-2523
    • Tsai, M.S.1    Hwang, S.M.2    Chen, K.D.3    Lee, Y.S.4    Hsu, L.W.5    Chang, Y.J.6    Wang, C.N.7    Peng, H.H.8    Chang, Y.L.9    Chao, A.S.10
  • 184
    • 42249105548 scopus 로고    scopus 로고
    • Differential gene expression profiling in HELLP syndrome placentas
    • Kang BY, Tsoi S, Zhu S, Su S, Kay HH. Differential gene expression profiling in HELLP syndrome placentas. Reprod Sci 2008;15:285-294.
    • (2008) Reprod Sci , vol.15 , pp. 285-294
    • Kang, B.Y.1    Tsoi, S.2    Zhu, S.3    Su, S.4    Kay, H.H.5
  • 185
    • 39449113641 scopus 로고    scopus 로고
    • Gene expression profile in labouring and non-labouring human placenta near term
    • Sitras V, Paulssen RH, Gronaas H, Vartun A, Acharya G. Gene expression profile in labouring and non-labouring human placenta near term. Mol Hum Reprod 2008;14:61-65.
    • (2008) Mol Hum Reprod , vol.14 , pp. 61-65
    • Sitras, V.1    Paulssen, R.H.2    Gronaas, H.3    Vartun, A.4    Acharya, G.5
  • 187
    • 67249088582 scopus 로고    scopus 로고
    • Functional genomic analysis of amniotic fluid cell-free mRNA suggests that oxidative stress is significant in Down syndrome fetuses
    • Slonim DK, Koide K, Johnson KL, Tantravahi U, Cowan JM, Jarrah Z, Bianchi DW. Functional genomic analysis of amniotic fluid cell-free mRNA suggests that oxidative stress is significant in Down syndrome fetuses. Proc Natl Acad Sci USA 2009;106:9425-9429.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 9425-9429
    • Slonim, D.K.1    Koide, K.2    Johnson, K.L.3    Tantravahi, U.4    Cowan, J.M.5    Jarrah, Z.6    Bianchi, D.W.7
  • 188
    • 0036010020 scopus 로고    scopus 로고
    • Use of cDNA arrays to generate differential expression profiles for inflammatory genes in human gestational membranes delivered at term and preterm
    • Marvin KW, Keelan JA, Eykholt RL, Sato TA, Mitchell MD. Use of cDNA arrays to generate differential expression profiles for inflammatory genes in human gestational membranes delivered at term and preterm. Mol Hum Reprod 2002;8:399-408.
    • (2002) Mol Hum Reprod , vol.8 , pp. 399-408
    • Marvin, K.W.1    Keelan, J.A.2    Eykholt, R.L.3    Sato, T.A.4    Mitchell, M.D.5
  • 189
    • 0036313981 scopus 로고    scopus 로고
    • Microarray analysis of differentially expressed genes in placental tissue of pre-eclampsia: Up-regulation of obesity-related genes
    • Reimer T, Koczan D, Gerber B, Richter D, Thiesen HJ, Friese K. Microarray analysis of differentially expressed genes in placental tissue of pre-eclampsia: up-regulation of obesity-related genes. Mol Hum Reprod 2002;8:674-680.
    • (2002) Mol Hum Reprod , vol.8 , pp. 674-680
    • Reimer, T.1    Koczan, D.2    Gerber, B.3    Richter, D.4    Thiesen, H.J.5    Friese, K.6
  • 190
    • 0036677986 scopus 로고    scopus 로고
    • Gene expression profile of trisomy 21 placentas: A potential approach for designing noninvasive techniques of prenatal diagnosis
    • Gross SJ, Ferreira JC, Morrow B, Dar P, Funke B, Khabele D, Merkatz I. Gene expression profile of trisomy 21 placentas: a potential approach for designing noninvasive techniques of prenatal diagnosis. Am J Obstet Gynecol 2002;187:457-462.
    • (2002) Am J Obstet Gynecol , vol.187 , pp. 457-462
    • Gross, S.J.1    Ferreira, J.C.2    Morrow, B.3    Dar, P.4    Funke, B.5    Khabele, D.6    Merkatz, I.7
  • 194
    • 33746932562 scopus 로고    scopus 로고
    • Genomewide oligonucleotide microarray analysis on placen-tae of pre-eclamptic pregnancies
    • Zhou R, Zhu Q, Wang Y, Ren Y, Zhang L, Zhou Y. Genomewide oligonucleotide microarray analysis on placen-tae of pre-eclamptic pregnancies. Gynecol Obstet Invest 2006;62:108-114.
    • (2006) Gynecol Obstet Invest , vol.62 , pp. 108-114
    • Zhou, R.1    Zhu, Q.2    Wang, Y.3    Ren, Y.4    Zhang, L.5    Zhou, Y.6
  • 195
    • 33744504458 scopus 로고    scopus 로고
    • Gene and protein expres-sion in the myometrium in pregnancy and labor
    • Breuiller-Fouche M, Germain G. Gene and protein expres-sion in the myometrium in pregnancy and labor. Reproduc-tion 2006;131:837-850.
    • (2006) Reproduction , vol.131 , pp. 837-850
    • Breuiller-Fouche, M.1    Germain, G.2
  • 196
    • 33746479025 scopus 로고    scopus 로고
    • Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature
    • Haddad R, Tromp G, Kuivaniemi H, Chaiworapongsa T, Kim YM, Mazor M, Romero R. Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature. Am J Obstet Gynecol 2006;195(2):394.e1-24.
    • (2006) Am J Obstet Gynecol , vol.195 , Issue.2
    • Haddad, R.1    Tromp, G.2    Kuivaniemi, H.3    Chaiworapongsa, T.4    Kim, Y.M.5    Mazor, M.6    Romero, R.7
  • 199
    • 35348997889 scopus 로고    scopus 로고
    • Comprehensive "proteomic profile" ofamnio-tic fluid may aid prenatal diagnosis
    • Hampton T. Comprehensive "proteomic profile" ofamnio-tic fluid may aid prenatal diagnosis. JAMA 2007;298:1751.
    • (2007) JAMA , vol.298 , pp. 1751
    • Hampton, T.1
  • 200
    • 39749152726 scopus 로고    scopus 로고
    • Proteomic analysis of human amniotic fluid from Rh(\) pregnancy
    • Hassan MI, Kumar V, Singh TP, Yadav S. Proteomic analysis of human amniotic fluid from Rh(\) pregnancy. Prenat Diagn 2008;28:102-108.
    • (2008) Prenat Diagn , vol.28 , pp. 102-108
    • Hassan, M.I.1    Kumar, V.2    Singh, T.P.3    Yadav, S.4
  • 204
    • 84934438506 scopus 로고    scopus 로고
    • Detection of new screening markers for fetal aneuploidies in maternal plasma: A proteomic approach
    • Reddy CS, Holzgreve W, Hahn S. Detection of new screening markers for fetal aneuploidies in maternal plasma: a proteomic approach. Methods Mol Biol 2008;444:311-326.
    • (2008) Methods Mol Biol , vol.444 , pp. 311-326
    • Reddy, C.S.1    Holzgreve, W.2    Hahn, S.3
  • 205
    • 55749103513 scopus 로고    scopus 로고
    • Comparative proteomic analysis of human placenta derived from assisted reproductive technology
    • Zhang Y, Zhang YL, Feng C, Wu YT, Liu AX, Sheng JZ, Cai J, Huang HF. Comparative proteomic analysis of human placenta derived from assisted reproductive technology. Proteomics 2008;8:4344-4356.
    • (2008) Proteomics , vol.8 , pp. 4344-4356
    • Zhang, Y.1    Zhang, Y.L.2    Feng, C.3    Wu, Y.T.4    Liu, A.X.5    Sheng, J.Z.6    Cai, J.7    Huang, H.F.8
  • 206
    • 66849121550 scopus 로고    scopus 로고
    • Preeclamptic toxemia: A disease ripe for proteomic discovery
    • Baker PN, Myers JE. Preeclamptic toxemia: a disease ripe for proteomic discovery. Expert Rev Proteomics 2009; 6: 107-110.
    • (2009) Expert Rev Proteomics , vol.6 , pp. 107-110
    • Baker, P.N.1    Myers, J.E.2
  • 208
    • 70049098161 scopus 로고    scopus 로고
    • A proof-of-principle gel-free proteomics strategy for the identification ofpredictive biomarkers for the onset of pre-eclampsia
    • Blankley RT, Gaskell SJ, Whetton AD, Dive C, Baker PN, Myers JE. A proof-of-principle gel-free proteomics strategy for the identification ofpredictive biomarkers for the onset of pre-eclampsia. BJOG 2009;116:1473-1480.
    • (2009) BJOG , vol.116 , pp. 1473-1480
    • Blankley, R.T.1    Gaskell, S.J.2    Whetton, A.D.3    Dive, C.4    Baker, P.N.5    Myers, J.E.6
  • 209
    • 67649229176 scopus 로고    scopus 로고
    • A proteomic approach identifies early pregnancy biomarkers for preeclampsia: Novel linkages between a predisposition to preeclampsia and cardiovascular disease
    • Blumenstein M, McMaster MT, Black MA, Wu S, Prakash R, Cooney J, McCowan LM, Cooper GJ, North RA. A proteomic approach identifies early pregnancy biomarkers for preeclampsia: novel linkages between a predisposition to preeclampsia and cardiovascular disease. Proteomics 2009;9: 2929-2945.
    • (2009) Proteomics , vol.9 , pp. 2929-2945
    • Blumenstein, M.1    McMaster, M.T.2    Ma, B.3    Wu, S.4    Prakash, R.5    Cooney, J.6    McCowan, L.M.7    Cooper, G.J.8    North, R.A.9
  • 210
    • 60549114533 scopus 로고    scopus 로고
    • Proteomic technologies for prenatal diagnostics: Advances and chal-lenges ahead
    • Choolani M, Narasimhan K, Kolla V, Hahn S. Proteomic technologies for prenatal diagnostics: advances and chal-lenges ahead. Expert Rev Proteomics 2009;6:87-101.
    • (2009) Expert Rev Proteomics , vol.6 , pp. 87-101
    • Choolani, M.1    Narasimhan, K.2    Kolla, V.3    Hahn, S.4
  • 213
    • 67649531210 scopus 로고    scopus 로고
    • Application of proteomics for diagnosis of fetal aneuploidies and pregnancy complications
    • Kolialexi A, Anagnostopoulos AK, Mavrou A, Tsangaris GT. Application of proteomics for diagnosis of fetal aneuploidies and pregnancy complications. J Proteomics 2009;72:731-739.
    • (2009) J Proteomics , vol.72 , pp. 731-739
    • Kolialexi, A.1    Anagnostopoulos, A.K.2    Mavrou, A.3    Tsangaris, G.T.4
  • 214
    • 60249083738 scopus 로고    scopus 로고
    • Placental proteomics: A shortcut to biological insight
    • Robinson JM, Vandre DD, Ackerman WE. Placental proteomics: a shortcut to biological insight. Placenta 2009; 30 (Suppl A):S83-S89.
    • (2009) Placenta , vol.30 , Issue.SUPPL. A
    • Robinson, J.M.1    Vandre, D.D.2    Ackerman, W.E.3
  • 215
    • 77949461098 scopus 로고    scopus 로고
    • Isobaric labeling and tandem mass spectrometry: A novel approach for profiling and quantifying proteins differentially expressed in amniotic fluid in preterm labor with and without intra-amniotic infection/inflammation
    • Romero R, Kusanovic JP, Gotsch F, Erez O, Vaisbuch E, Mazaki-Tovi S, Moser A, Tam S, Leszyk J, Master SR, et al. Isobaric labeling and tandem mass spectrometry: a novel approach for profiling and quantifying proteins differentially expressed in amniotic fluid in preterm labor with and without intra-amniotic infection/inflammation. J Matern Fetal Neonatal Med 2010;23:261-280.
    • (2010) J Matern Fetal Neonatal Med , vol.23 , pp. 261-280
    • Romero, R.1    Kusanovic, J.P.2    Gotsch, F.3    Erez, O.4    Vaisbuch, E.5    Mazaki-Tovi, S.6    Moser, A.7    Tam, S.8    Leszyk, J.9    Master, S.R.10
  • 216
    • 67649099360 scopus 로고    scopus 로고
    • Network analyses of differentially expressed proteins in amniotic fluid supernatant associated with abnormal human karyotypes
    • Wang TH, Chao AS, Chen JK, Chao A, Chang YL, Cheng PJ, Chang SD, Wang HS. Network analyses of differentially expressed proteins in amniotic fluid supernatant associated with abnormal human karyotypes. Fertil Steril 2009;92:96-107.
    • (2009) Fertil Steril , vol.92 , pp. 96-107
    • Wang, T.H.1    Chao, A.S.2    Chen, J.K.3    Chao, A.4    Chang, Y.L.5    Cheng, P.J.6    Chang, S.D.7    Wang, H.S.8
  • 217
    • 70449715729 scopus 로고    scopus 로고
    • Differential proteome analysis ofthe preeclamptic placenta using optimized protein extraction
    • Centlow M, Hansson SR, Welinder C. Differential proteome analysis ofthe preeclamptic placenta using optimized protein extraction. J Biomed Biotechnol 2010;2010:458-748.
    • (2010) J Biomed Biotechnol , vol.2010 , pp. 458-748
    • Centlow, M.1    Hansson, S.R.2    Welinder, C.3
  • 218
    • 74049085513 scopus 로고    scopus 로고
    • Quantitative proteomics analysis ofmaternal plasma in Down syndrome pregnancies using isobaric tagging reagent (iTRAQ)
    • Kolla V, Jeno P, Moes S, Tercanli S, Lapaire O, Choolani M, Hahn S. Quantitative proteomics analysis ofmaternal plasma in Down syndrome pregnancies using isobaric tagging reagent (iTRAQ). J Biomed Biotechnol 2010;2010: 952047.
    • (2010) J Biomed Biotechnol , vol.2010 , pp. 952047
    • Kolla, V.1    Jeno, P.2    Moes, S.3    Tercanli, S.4    Lapaire, O.5    Choolani, M.6    Hahn, S.7
  • 219
    • 34248203177 scopus 로고    scopus 로고
    • The cervical-vaginal fluid proteome and possible biomarkers of preterm birth
    • Cottingham K. The cervical-vaginal fluid proteome and possible biomarkers of preterm birth. J Proteome Res 2007;6:1241-1242.
    • (2007) J Proteome Res , vol.6 , pp. 1241-1242
    • Cottingham, K.1
  • 226
    • 33745086566 scopus 로고    scopus 로고
    • Proteomic analysis of recurrent spontaneous abortion: Identification of an inadequately expressed set of proteins in human follicular fluid
    • Kim YS, Kim MS, Lee SH, Choi BC, Lim JM, Cha KY, Baek KH. Proteomic analysis of recurrent spontaneous abortion: identification of an inadequately expressed set of proteins in human follicular fluid. Proteomics 2006;6:3445-3454.
    • (2006) Proteomics , vol.6 , pp. 3445-3454
    • Kim, Y.S.1    Kim, M.S.2    Lee, S.H.3    Choi, B.C.4    Lim, J.M.5    Cha, K.Y.6    Baek, K.H.7
  • 232
    • 85047682792 scopus 로고    scopus 로고
    • Functional genomics and proteomics in term and preterm parturition
    • Romero R, Kuivaniemi H, Tromp G. Functional genomics and proteomics in term and preterm parturition. J Clin Endocrinol Metab 2002;87:2431-2434.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2431-2434
    • Romero, R.1    Kuivaniemi, H.2    Tromp, G.3
  • 233
    • 34447536646 scopus 로고    scopus 로고
    • Role of metabo-lomic analysis of biomarkers in the management of male infertility
    • Deepinder F, Chowdary HT, Agarwal A. Role of metabo-lomic analysis of biomarkers in the management of male infertility. Expert Rev Mol Diagn 2007;7:351-358.
    • (2007) Expert Rev Mol Diagn , vol.7 , pp. 351-358
    • Deepinder, F.1    Chowdary, H.T.2    Agarwal, A.3
  • 234
    • 35648974233 scopus 로고    scopus 로고
    • Noninvasive metabolomic profiling of embryo culture media using Raman and near-infrared spectroscopy correlates with reproductive potential ofembryos in women undergoing in vitro fertilization
    • Seli E, Sakkas D, Scott R, Kwok SC, Rosendahl SM, Burns DH. Noninvasive metabolomic profiling of embryo culture media using Raman and near-infrared spectroscopy correlates with reproductive potential ofembryos in women undergoing in vitro fertilization. Fertil Steril 2007;88:1350-1357.
    • (2007) Fertil Steril , vol.88 , pp. 1350-1357
    • Seli, E.1    Sakkas, D.2    Scott, R.3    Kwok, S.C.4    Rosendahl, S.M.5    Burns, D.H.6
  • 235
    • 34547094578 scopus 로고    scopus 로고
    • Metabolomics: Approaches to asses-sing oocyte and embryo quality
    • Singh R, Sinclair KD. Metabolomics: approaches to asses-sing oocyte and embryo quality. Theriogenology 2007;68 (Suppl 1):S56-S62.
    • (2007) Theriogenology , vol.68 , Issue.SUPPL. 1
    • Singh, R.1    Sinclair, K.D.2
  • 236
    • 58249110516 scopus 로고    scopus 로고
    • Metabolomics and its application for non-invasive embryo assessment in IVF
    • Botros L, Sakkas D, Seli E. Metabolomics and its application for non-invasive embryo assessment in IVF. Mol Hum Reprod 2008;14:679-690.
    • (2008) Mol Hum Reprod , vol.14 , pp. 679-690
    • Botros, L.1    Sakkas, D.2    Seli, E.3
  • 237
    • 43149121764 scopus 로고    scopus 로고
    • Assessment ofembryo viability in assisted reproductive technology: Shortcomings of current ap-proaches and the emerging role ofmetabolomics
    • Bromer JG, Seli E. Assessment ofembryo viability in assisted reproductive technology: shortcomings of current ap-proaches and the emerging role ofmetabolomics. Curr Opin Obstet Gynecol 2008;20:234-241.
    • (2008) Curr Opin Obstet Gynecol , vol.20 , pp. 234-241
    • Bromer, J.G.1    Seli, E.2
  • 238
    • 45849120634 scopus 로고    scopus 로고
    • Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: A prospective blinded pilot study
    • Scott R, Seli E, Miller K, Sakkas D, Scott K, Burns DH. Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded pilot study. Fertil Steril 2008;90:77-83.
    • (2008) Fertil Steril , vol.90 , pp. 77-83
    • Scott, R.1    Seli, E.2    Miller, K.3    Sakkas, D.4    Scott, K.5    Burns, D.H.6
  • 239
    • 56649121905 scopus 로고    scopus 로고
    • Noninvasive metabolomic profiling ofembryo culture media using proton nuclear magnetic resonance correlates with reproductive potential of embryos in women undergoing in vitro fertiliza-tion
    • Seli E, Botros L, Sakkas D, Burns DH. Noninvasive metabolomic profiling ofembryo culture media using proton nuclear magnetic resonance correlates with reproductive potential of embryos in women undergoing in vitro fertiliza-tion. Fertil Steril 2008;90:2183-2189.
    • (2008) Fertil Steril , vol.90 , pp. 2183-2189
    • Seli, E.1    Botros, L.2    Sakkas, D.3    Burns, D.H.4
  • 243
    • 49049091730 scopus 로고    scopus 로고
    • Baker PN, Kell DB. Analysis of the metabolic footprint and tissue metabolome of placental villous explants cultured at different oxygen tensions reveals novel redox biomarkers. Placenta
    • Heazell AE, Brown M, Dunn WB, Worton SA, Crocker IP, Baker PN, Kell DB. Analysis of the metabolic footprint and tissue metabolome of placental villous explants cultured at different oxygen tensions reveals novel redox biomarkers. Placenta 2008;29:691-698.
    • (2008) , vol.29 , pp. 691-698
    • Heazell, A.E.1    Brown, M.2    Dunn, W.B.3    Worton, S.A.4    Crocker, I.P.5
  • 244
    • 70449099323 scopus 로고    scopus 로고
    • Changes in the metabolic footprint of placental explant-conditioned culture medium identifies metabolic distur-bances related to hypoxia and pre-eclampsia
    • Dunn WB, Brown M, Worton SA, Crocker IP, Broadhurst D, Horgan R, Kenny LC, Baker PN, Kell DB, Heazell AE. Changes in the metabolic footprint of placental explant-conditioned culture medium identifies metabolic distur-bances related to hypoxia and pre-eclampsia. Placenta 2009;30:974-980.
    • (2009) Placenta , vol.30 , pp. 974-980
    • Dunn, W.B.1    Brown, M.2    Worton, S.A.3    Crocker, I.P.4    Broadhurst, D.5    Horgan, R.6    Kenny, L.C.7    Baker, P.N.8    Kell, D.B.9    Heazell, A.E.10
  • 245
    • 0027521595 scopus 로고
    • Analysis of saturated phosphatidylcholine in amniotic fluid by 31P NMR
    • Pearce JM, Krone JT, Pappas AA, Komoroski RA. Analysis of saturated phosphatidylcholine in amniotic fluid by 31P NMR. Magn Reson Med 1993;30:476-484.
    • (1993) Magn Reson Med , vol.30 , pp. 476-484
    • Pearce, J.M.1    Krone, J.T.2    Pappas, A.A.3    Komoroski, R.A.4
  • 247
    • 0028155888 scopus 로고
    • Metabolic profiling of amniotic fluid by proton nuclear magnetic resonance spectroscopy: Correlation with fetal maturation and other clinical variables
    • Bock JL. Metabolic profiling of amniotic fluid by proton nuclear magnetic resonance spectroscopy: correlation with fetal maturation and other clinical variables. Clin Chem 1994;40:56-61.
    • (1994) Clin Chem , vol.40 , pp. 56-61
    • Bock, J.L.1


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