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Volumn 60, Issue 2, 2011, Pages 225-241

Reduced progesterone metabolites in human late pregnancy

Author keywords

GC MS; Metabolome; Neuroactive steroids; Plasma; Pregnancy

Indexed keywords


EID: 79959255971     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: 10.33549/physiolres.932077     Document Type: Review
Times cited : (26)

References (115)
  • 1
    • 0017683003 scopus 로고
    • Serum oestrogens and progesterone in mother and infant at delivery
    • ANTONIPILLAI I, MURPHY BE, 1977: Serum oestrogens and progesterone in mother and infant at delivery. Br J Obstet Gynaecol 84: 179-185.
    • (1977) Br J Obstet Gynaecol , vol.84 , pp. 179-185
    • Antonipillai, I.1    Murphy, B.E.2
  • 3
    • 0034487729 scopus 로고    scopus 로고
    • Tissue- and sitespecific gene expression of type 2 17beta-hydroxysteroid dehydrogenase: in situ hybridization and specificenzymatic activity studies in human placental endothelial cells of the arterial system
    • BONENFANT M, BLOMQUIST CH, PROVOST PR, DROLET R, D'ASCOLI P, TREMBLAY Y, 2000: Tissue- and sitespecific gene expression of type 2 17beta-hydroxysteroid dehydrogenase: in situ hybridization and specificenzymatic activity studies in human placental endothelial cells of the arterial system. J Clin Endocrinol Metab 85: 4841-4850.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4841-4850
    • Bonenfant, M.1    Blomquist, C.H.2    Provost, P.R.3    Drolet, R.4    D'Ascoli, P.5    Tremblay, Y.6
  • 4
    • 0034042433 scopus 로고    scopus 로고
    • Localization of type 1 17beta-hydroxysteroid dehydrogenase mRNA and protein in syncytiotrophoblasts and invasive cytotrophoblasts in the human term villi
    • BONENFANT M, PROVOST PR, DROLET R, TREMBLAY Y, 2000: Localization of type 1 17beta-hydroxysteroid dehydrogenase mRNA and protein in syncytiotrophoblasts and invasive cytotrophoblasts in the human term villi. J Endocrinol 165: 217-222.
    • (2000) J Endocrinol , vol.165 , pp. 217-222
    • Bonenfant, M.1    Provost, P.R.2    Drolet, R.3    Tremblay, Y.4
  • 7
    • 0018377150 scopus 로고
    • Interrelationships of circulating maternal steroid concentrations in third trimester pregnancies. II. C18 and C19 steroids: estradiol, estriol, dehydroepiandrosterone, dehydroepiandrosterone sulfate, delta 5-androstenediol, delta 4-androstenedione, testosterone, and dihydrotestosterone
    • BUSTER JE, CHANG RJ, PRESTON DL, ELASHOFF RM, COUSINS LM, ABRAHAM GE, HOBEL CJ, MARSHALL JR, 1979: Interrelationships of circulating maternal steroid concentrations in third trimester pregnancies. II. C18 and C19 steroids: estradiol, estriol, dehydroepiandrosterone, dehydroepiandrosterone sulfate, delta 5-androstenediol, delta 4-androstenedione, testosterone, and dihydrotestosterone. J Clin ndocrinol Metab 48: 139-142.
    • (1979) J Clin Endocrinol Metab , vol.48 , pp. 139-142
    • Buster, J.E.1    Chang, R.J.2    Preston, D.L.3    Elashoff, R.M.4    Cousins, L.M.5    Abraham, G.E.6    Hobel, C.J.7    Marshall, J.R.8
  • 9
    • 0035951661 scopus 로고    scopus 로고
    • Genomic organization of a human 5beta-reductase and its pseudogene and substrate selectivity of the expressed enzyme
    • CHARBONNEAU A, THE VL, 2001: Genomic organization of a human 5beta-reductase and its pseudogene and substrate selectivity of the expressed nzyme. Biochim Biophys Acta 1517: 228-235.
    • (2001) Biochim Biophys Acta , vol.1517 , pp. 228-235
    • Charbonneau, A.1    The, V.L.2
  • 10
    • 0033052918 scopus 로고    scopus 로고
    • Physiological modulation of GABA(A) receptor plasticity by progesterone metabolites
    • CONCAS A, FOLLESA P, BARBACCIA ML, PURDY RH, BIGGIO G, 1999: Physiological modulation of GABA(A) receptor plasticity by progesterone metabolites. Eur J Pharmacol 375: 225-235.
    • (1999) Eur J Pharmacol , vol.375 , pp. 225-235
    • Concas, A.1    Follesa, P.2    Barbaccia, M.L.3    Purdy, R.H.4    Biggio, G.5
  • 12
    • 0018348136 scopus 로고
    • 20 alpha-Hydroxysteroid oxidoreductase activity and 20 alpha-dihydroprogesterone concentration in human placenta before and after parturition
    • DIAZ-ZAGOYA JC, WIEST WG, ARIAS F, 1979:. 20 alpha-Hydroxysteroid oxidoreductase activity and. 20 alpha-dihydroprogesterone concentration in human placenta before and after parturition. Am J Obstet Gynecol 133: 673-676.
    • (1979) Am J Obstet Gynecol , vol.133 , pp. 673-676
    • Diaz-Zagoya, J.C.1    Wiest, W.G.2    Arias, F.3
  • 13
    • 0035046968 scopus 로고    scopus 로고
    • Regulation of uterine gamma-aminobutyric acid(A) receptor subunit expression throughout pregnancy
    • FUJII E, MELLON SH, 2001: Regulation of uterine gamma-aminobutyric acid(A) receptor subunit expression throughout pregnancy. Endocrinology 42: 1770-1777.
    • (2001) Endocrinology , vol.142 , pp. 1770-1777
    • Fujii, E.1    Mellon, S.H.2
  • 14
    • 0022640611 scopus 로고
    • Growth and function of the placenta - with special reference to various enzymes involved in the biosynthesis of steroids in the human placenta
    • FUKUDA M, OKUYAMA T, FURUYA H, 1986: Growth and function of the placenta - with special reference to various enzymes involved in the biosynthesis of steroids in the human placenta. Nippon Sanka Fujinka Gakkai Zasshi 38: 411-416.
    • (1986) Nippon Sanka Fujinka Gakkai Zasshi , vol.38 , pp. 411-416
    • Fukuda, M.1    Okuyama, T.2    Furuya, H.3
  • 15
    • 29944436779 scopus 로고    scopus 로고
    • 3alpha-reduced neuroactive steroids and their precursors during pregnancy and the postpartum period
    • GILBERT EVANS SE, ROSS LE, SELLERS EM, PURDY RH, ROMACH MK, 2005: 3alpha-reduced neuroactive steroids and their precursors during pregnancy and the postpartum period. Gynecol Endocrinol 21: 268-279.
    • (2005) Gynecol Endocrinol , vol.21 , pp. 268-279
    • Gilbert Evans, S.E.1    Ross, L.E.2    Sellers, E.M.3    Purdy, R.H.4    Romach, M.K.5
  • 16
    • 0023036969 scopus 로고
    • High levels of corticotropin-releasing hormone immunoactivity in maternal and fetal plasma during pregnancy
    • GOLAND RS, WARDLAW SL, STARK RI, BROWN LS JR, FRANTZ AG, 1986: High levels of corticotropin-releasing hormone immunoactivity in maternal and fetal plasma during pregnancy. J Clin Endocrinol Metab 63: 1199-1203.
    • (1986) J Clin Endocrinol Metab , vol.63 , pp. 1199-1203
    • Goland, R.S.1    Wardlaw, S.L.2    Stark, R.I.3    Brown Jr., L.S.4    Frantz, A.G.5
  • 17
    • 0028309427 scopus 로고
    • Epitopic heterogeneity of human 3 beta-hydroxysteroid dehydrogenase in villous and extravillous human trophoblast
    • HAWES CS, MCBRIDE MW, PETROPOULOS A, MUELLER UW, SUTCLIFFE RG, 1994: Epitopic heterogeneity of human 3 beta-hydroxysteroid dehydrogenase in villous and extravillous human trophoblast. J Mol Endocrinol 12: 273-281.
    • (1994) J Mol Endocrinol , vol.12 , pp. 273-281
    • Hawes, C.S.1    Mcbride, M.W.2    Petropoulos, A.3    Mueller, U.W.4    Sutcliffe, R.G.5
  • 18
    • 0034791854 scopus 로고    scopus 로고
    • Characterization and localization of human type10 17beta-hydroxysteroid dehydrogenase
    • HE XY, MERZ G, YANG YZ, MEHTA P, SCHULZ H, YANG SY, 2001: Characterization and localization of human type10 17beta-hydroxysteroid ehydrogenase. Eur J Biochem 268: 4899-4907.
    • (2001) Eur J Biochem , vol.268 , pp. 4899-4907
    • He, X.Y.1    Merz, G.2    Yang, Y.Z.3    Mehta, P.4    Schulz, H.5    Yang, S.Y.6
  • 19
    • 0347480518 scopus 로고    scopus 로고
    • Oxidative 3alpha-hydroxysteroid dehydrogenase activity of human type 10 17beta-hydroxysteroid dehydrogenase
    • HE XY, YANG YZ, PEEHL DM, LAUDERDALE A, SCHULZ H, YANG SY, 2003: Oxidative 3alpha-hydroxysteroid dehydrogenase activity of human type 10 17beta-hydroxysteroid dehydrogenase. J Steroid Biochem Mol Biol 87:. 191-198.
    • (2003) J Steroid Biochem Mol Biol , vol.87 , pp. 191-198
    • He, X.Y.1    Yang, Y.Z.2    Peehl, D.M.3    Lauderdale, A.4    Schulz, H.5    Yang, S.Y.6
  • 23
    • 0034739778 scopus 로고    scopus 로고
    • Neuroactive steroids, their precursors, and polar conjugates during parturition and postpartum in maternal and umbilical blood: 1. Identification and simultaneous determination of pregnanolone isomers
    • HILL M, PARIZEK A, BICIKOVA M, HAVLIKOVA H, KLAK J, FAIT T, CIBULA D, HAMPL R, CEGAN A, SULCOVA J, STARKA L, 2000: Neuroactive steroids, their precursors, and polar conjugates during parturition and postpartum in maternal and umbilical blood: 1. Identification and simultaneous determination of pregnanolone isomers. J Steroid Biochem Mol Biol 75: 237-244.
    • (2000) J Steroid Biochem Mol Biol , vol.75 , pp. 237-244
    • Hill, M.1    Parizek, A.2    Bicikova, M.3    Havlikova, H.4    Klak, J.5    Fait, T.6    Cibula, D.7    Hampl, R.8    Cegan, A.9    Sulcova, J.10    Starka, L.11
  • 27
    • 33847789469 scopus 로고    scopus 로고
    • Stress in pregnancy activates neurosteroid production in the fetal brain
    • HIRST JJ, YAWNO T, NGUYEN P, WALKER DW, 2006: Stress in pregnancy activates neurosteroid production in the fetal brain. Neuroendocrinology 84: 264-274.
    • (2006) Neuroendocrinology , vol.84 , pp. 264-274
    • Hirst, J.J.1    Yawno, T.2    Nguyen, P.3    Walker, D.W.4
  • 28
    • 0034703043 scopus 로고    scopus 로고
    • Molecular characterization of a first human 3(alpha→beta)-hydroxysteroid epimerase
    • HUANG XF, LUU-THE V, 2000: Molecular characterization of a first human 3(alpha→beta)-hydroxysteroid epimerase. J Biol Chem 275: 29452-9457.
    • (2000) J Biol Chem , vol.275 , pp. 29452-29457
    • Huang, X.F.1    Luu-The, V.2
  • 29
    • 0016431086 scopus 로고
    • Properties of hydroxylase systems in the human fetal liver active on free and sulfoconjugated steroids
    • INGELMAN-SUNDBERG M, RANE A, GUSTAFASSON JA, 1975: Properties of hydroxylase systems in the human fetal liver active on free and ulfoconjugated steroids. Biochemistry 14: 429-437.
    • (1975) Biochemistry , vol.14 , pp. 429-437
    • Ingelman-Sundberg, M.1    Rane, A.2    Gustafasson, J.A.3
  • 31
    • 0013925431 scopus 로고
    • In vivo steroid biogenesis and metabolism in the human term placenta. I. In situ placental perfusion with isotopic pregnenolone
    • JAFFE RB, LEDGER WJ, 1966: In vivo steroid biogenesis and metabolism in the human term placenta. I. In situ placental perfusion with isotopic regnenolone. Steroids 8: 61-78.
    • (1966) Steroids , vol.8 , pp. 61-78
    • Jaffe, R.B.1    Ledger, W.J.2
  • 32
    • 65649152952 scopus 로고    scopus 로고
    • Human cytosolic hydroxysteroid dehydrogenases of the aldo-ketoreductase superfamily catalyze reduction of conjugated steroids: implications for phase I and phase II steroid hormone metabolism
    • JIN Y, DUAN L, LEE SH, KLOOSTERBOER HJ, BLAIR IA, PENNING TM, 2009: Human cytosolic hydroxysteroid dehydrogenases of the aldo-ketoreductase superfamily catalyze reduction of conjugated steroids: implications for phase I and phase II steroid hormone metabolism. J Biol Chem 284: 10013-0022.
    • (2009) J Biol Chem , vol.284 , pp. 10013-10022
    • Jin, Y.1    Duan, L.2    Lee, S.H.3    Kloosterboer, H.J.4    Blair, I.A.5    Penning, T.M.6
  • 33
    • 0034743536 scopus 로고    scopus 로고
    • Steroid 5alpha-reductases and 3alpha-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism
    • JIN Y, PENNING TM, 2001: Steroid 5alpha-reductases and 3alpha-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism. Best Pract es Clin Endocrinol Metab 15: 79-94.
    • (2001) Best Pract Res Clin Endocrinol Metab , vol.15 , pp. 79-94
    • Jin, Y.1    Penning, T.M.2
  • 34
    • 0035964182 scopus 로고    scopus 로고
    • Crystal structure of human type III 3alpha-hydroxysteroid dehydrogenase/bile acid binding protein complexed with NADP(+) and ursodeoxycholate
    • JIN Y, STAYROOK SE, ALBERT RH, PALACKAL NT, PENNING TM, LEWIS M, 2001: Crystal structure of human type III 3alpha-hydroxysteroid dehydrogenase/bile acid binding protein complexed with NADP(+) and ursodeoxycholate. Biochemistry 40: 10161-10168.
    • (2001) Biochemistry , vol.40 , pp. 10161-10168
    • Jin, Y.1    Stayrook, S.E.2    Albert, R.H.3    Palackal, N.T.4    Penning, T.M.5    Lewis, M.6
  • 35
    • 0027937414 scopus 로고
    • Comparison of eltanolone and propofol in anesthesia for termination of pregnancy
    • KALLELA H, HAASIO J, KORTTILA K, 1994: Comparison of eltanolone and propofol in anesthesia for termination of pregnancy. Anesth Analg 79: 12-516.
    • (1994) Anesth Analg , vol.79 , pp. 512-516
    • Kallela, H.1    Haasio, J.2    Korttila, K.3
  • 36
    • 35848931028 scopus 로고    scopus 로고
    • Relationships of circulating pregnanolone isomers and their polar conjugates to the status of sex, menstrual cycle, and pregnancy
    • KANCHEVA R, HILL M, CIBULA D, VCELAKOVA H, KANCHEVA L, VRBIKOVA J, FAIT T, PARIZEK A, STARKA L, 2007: Relationships of circulating pregnanolone isomers and their polar conjugates to the status of sex, menstrual cycle, and pregnancy. J Endocrinol. 195: 67-78.
    • (2007) J Endocrinol , vol.195 , pp. 67-78
    • Kancheva, R.1    Hill, M.2    Cibula, D.3    Vcelakova, H.4    Kancheva, L.5    Vrbikova, J.6    Fait, T.7    Parizek, A.8    Starka, L.9
  • 38
    • 0035041695 scopus 로고    scopus 로고
    • Modulation of potassium current characteristics in human myometrial smooth muscle by 17beta-estradiol and progesterone
    • KNOCK GA, TRIBE RM, HASSONI AA, AARONSON PI, 2001: Modulation of potassium current characteristics in human myometrial smooth muscle by 17beta-estradiol and progesterone. Biol Reprod 64: 1526-1534.
    • (2001) Biol Reprod , vol.64 , pp. 1526-1534
    • Knock, G.A.1    Tribe, R.M.2    Hassoni, A.A.3    Aaronson, P.I.4
  • 39
    • 0021021533 scopus 로고
    • Conversion of testosterone and androstenedione to 5 beta-androstanes by adult male hamster liver cytosol
    • KOCHAKIAN CD, 1983: Conversion of testosterone and androstenedione to 5 beta-androstanes by adult male hamster liver cytosol. J Steroid iochem. 19: 1521-1526.
    • (1983) J Steroid Biochem , vol.19 , pp. 1521-1526
    • Kochakian, C.D.1
  • 42
    • 0032727093 scopus 로고    scopus 로고
    • Determination of cDNA, gene structure and chromosomal localization of the novel human 17beta-hydroxysteroid dehydrogenase type 7 (1)
    • KRAZEISEN A, BREITLING R, IMAI K, FRITZ S, MOLLER G, ADAMSKI J, 1999: Determination of cDNA, gene structure and chromosomal localization of the novel human 17beta-hydroxysteroid dehydrogenase type 7(1). FEBS Lett 460: 373-379.
    • (1999) FEBS Lett , vol.460 , pp. 373-379
    • Krazeisen, A.1    Breitling, R.2    Imai, K.3    Fritz, S.4    Moller, G.5    Adamski, J.6
  • 43
    • 0018627642 scopus 로고
    • In vitro inhibition of rat uterine contractility induced by 5 alpha and 5 beta progestins
    • KUBLI-GARFIAS C, MEDRANO-CONDE L, BEYER C, BONDANI A, 1979: In vitro inhibition of rat uterine contractility induced by 5 alpha and 5 eta progestins. Steroids 34: 609-617.
    • (1979) Steroids , vol.34 , pp. 609-617
    • Kubli-Garfias, C.1    Medrano-Conde, L.2    Beyer, C.3    Bondani, A.4
  • 44
    • 66149161668 scopus 로고    scopus 로고
    • Pregnanolone sulfate promotes desensitization of activated NMDA receptors
    • KUSSIUS CL, KAUR N, POPESCU GK, 2009: Pregnanolone sulfate promotes desensitization of activated NMDA receptors. J Neurosci 29: 6819-827.
    • (2009) J Neurosci , vol.29 , pp. 6819-6827
    • Kussius, C.L.1    Kaur, N.2    Popescu, G.K.3
  • 45
    • 0030750270 scopus 로고    scopus 로고
    • Expression of CYP3A in the human liver - evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth
    • LACROIX D, SONNIER M, MONCION A, CHERON G, CRESTEIL T, 1997: Expression of CYP3A in the human liver - evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth. Eur J Biochem 247: 625-634.
    • (1997) Eur J Biochem , vol.247 , pp. 625-634
    • Lacroix, D.1    Sonnier, M.2    Moncion, A.3    Cheron, G.4    Cresteil, T.5
  • 48
    • 17644373045 scopus 로고    scopus 로고
    • Expression of 3beta-hydroxysteroid dehydrogenase type 1, P450 aromatase and 17beta-hydroxysteroid dehydrogenase types 1, 2, 5 and 7 mRNAs in human early and mid-gestation placentas
    • LI Y, ISOMAA V, PULKKA A, HERVA R, PELTOKETO H, VIHKO P, 2005: Expression of 3beta-hydroxysteroid dehydrogenase type 1, P450 aromatase, and 17beta-hydroxysteroid dehydrogenase types 1, 2, 5 and 7 mRNAs in human early and mid-gestation placentas. Placenta 26: 387-392.
    • (2005) Placenta , vol.26 , pp. 387-392
    • Li, Y.1    Isomaa, V.2    Pulkka, A.3    Herva, R.4    Peltoketo, H.5    Vihko, P.6
  • 49
    • 33644973274 scopus 로고    scopus 로고
    • Structural basis of the multispecificity demonstrated by 17beta-hydroxysteroid dehydrogenase types 1 and 5
    • LIN SX, SHI R, QIU W, AZZI A, ZHU DW, DABBAGH HA, ZHOU M, 2006: Structural basis of the multispecificity demonstrated by 17beta-hydroxysteroid dehydrogenase types 1 and 5. Mol Cell Endocrinol 248: 38-46.
    • (2006) Mol Cell Endocrinol , vol.248 , pp. 38-46
    • Lin, S.X.1    Shi, R.2    Qiu, W.3    Azzi, A.4    Zhu, D.W.5    Dabbagh, H.A.6    Zhou, M.7
  • 50
    • 0037008367 scopus 로고    scopus 로고
    • Allopregnanolone attenuates N-methyl-D-aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture
    • LOCKHART EM, WARNER DS, PEARLSTEIN RD, PENNING DH, MEHRABANI S, BOUSTANY RM, 2002: Allopregnanolone attenuates N-methyl-D-aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture. Neurosci Lett 328: 33-36.
    • (2002) Neurosci Lett , vol.328 , pp. 33-36
    • Lockhart, E.M.1    Warner, D.S.2    Pearlstein, R.D.3    Penning, D.H.4    Mehrabani, S.5    Boustany, R.M.6
  • 51
    • 0025091303 scopus 로고
    • Serum concentrations of progesterone and 5 alpha-pregnane-3 20-dione during labor and early post partum
    • LOFGREN M, BACKSTROM T, 1990: Serum concentrations of progesterone and 5 alpha-pregnane-3,20-dione during labor and early post partum. cta Obstet Gynecol Scand 69: 123-126.
    • (1990) Acta Obstet Gynecol Scand , vol.69 , pp. 123-126
    • Lofgren, M.1    Backstrom, T.2
  • 52
    • 0026594696 scopus 로고
    • Effects in vitro of progesterone and two 5 alpha-reduced progestins, 5 alpha-pregnane-3,20-dione and 5 alpha-pregnane-3 alpha-ol-20-one, on contracting human myometrium at term
    • LOFGREN M, HOLST J, BACKSTROM T, 1992: Effects in vitro of progesterone and two 5 alpha-reduced progestins, 5 alpha-pregnane-3,20-dione and 5 alpha-pregnane-3 alpha-ol-20-one, on contracting human myometrium at term. Acta Obstet Gynecol Scand 71: 28-33.
    • (1992) Acta Obstet Gynecol Scand , vol.71 , pp. 28-33
    • Lofgren, M.1    Holst, J.2    Backstrom, T.3
  • 54
    • 33947216707 scopus 로고    scopus 로고
    • Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity
    • LUKACIK P, KELLER B, BUNKOCZI G, KAVANAGH KL, LEE WH, ADAMSKI J, OPPERMANN U, 2007: Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity. Biochem J 402: 419-427.
    • (2007) Biochem J , vol.402 , pp. 419-427
    • Lukacik, P.1    Keller, B.2    Bunkoczi, G.3    Kavanagh, K.L.4    Lee, W.H.5    Adamski, J.6    Oppermann, U.7
  • 55
    • 18844481386 scopus 로고    scopus 로고
    • Allopregnanolone-stimulated GABA-mediated chloride ion flux is inhibited by 3beta-hydroxy-5alpha-pregnan-20-one (isoallopregnanolone)
    • LUNDGREN P, STROMBERG J, BACKSTROM T, WANG M, 2003: Allopregnanolone-stimulated GABA-mediated chloride ion flux is inhibited by 3beta-hydroxy-5alpha-pregnan-20-one (isoallopregnanolone). Brain Res 982: 45-53.
    • (2003) Brain Res , vol.982 , pp. 45-53
    • Lundgren, P.1    Stromberg, J.2    Backstrom, T.3    Wang, M.4
  • 56
    • 68049148067 scopus 로고    scopus 로고
    • Excitability changes related to GABAA receptor plasticity during pregnancy
    • MAGUIRE J, FERANDO I, SIMONSEN C, MODY I, 2009: Excitability changes related to GABAA receptor plasticity during pregnancy. J Neurosci 9: 9592-9601.
    • (2009) J Neurosci , vol.29 , pp. 9592-9601
    • Maguire, J.1    Ferando, I.2    Simonsen, C.3    Mody, I.4
  • 57
    • 0025872155 scopus 로고
    • Steroid control of uterine motility via gamma-aminobutyric acidA receptors in the rabbit: a novel mechanism?
    • MAJEWSKA MD, VAUPEL DB, 1991: Steroid control of uterine motility via gamma-aminobutyric acidA receptors in the rabbit: a novel mechanism? J ndocrinol 131: 427-434
    • (1991) J Endocrinol , vol.131 , pp. 427-434
    • Majewska, M.D.1    Vaupel, D.B.2
  • 58
    • 0036185532 scopus 로고    scopus 로고
    • Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids
    • MALAYEV A, GIBBS TT, FARB DH, 2002: Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids. Br J Pharmacol 135: 901-909.
    • (2002) Br J Pharmacol , vol.135 , pp. 901-909
    • Malayev, A.1    Gibbs, T.T.2    Farb, D.H.3
  • 60
    • 0018873758 scopus 로고
    • Progesterone, 17-hydroxyprogesterone, estradiol, and estriol in late pregnancy and labor
    • MATHUR RS, LANDGREBE S, WILLIAMSON HO, 1980: Progesterone, 17-hydroxyprogesterone, estradiol, and estriol in late pregnancy and labor. m J Obstet Gynecol 136: 25-27.
    • (1980) Am J Obstet Gynecol , vol.136 , pp. 25-27
    • Mathur, R.S.1    Landgrebe, S.2    Williamson, H.O.3
  • 61
    • 0031759084 scopus 로고    scopus 로고
    • Identification of a principal mRNA species for human 3alpha-hydroxysteroid dehydrogenase isoform (AKR1C3) that exhibits high prostaglandin D2 11-ketoreductase activity
    • MATSUURA K, SHIRAISHI H, HARA A, SATO K, DEYASHIKI Y, NINOMIYA M, SAKAI S, 1998: Identification of a principal mRNA species for human 3alpha-hydroxysteroid dehydrogenase isoform (AKR1C3) that exhibits high prostaglandin D2 11-ketoreductase activity. J Biochem 124: 940-946.
    • (1998) J Biochem , vol.124 , pp. 940-946
    • Matsuura, K.1    Shiraishi, H.2    Hara, A.3    Sato, K.4    Deyashiki, Y.5    Ninomiya, M.6    Sakai, S.7
  • 62
    • 0018769219 scopus 로고
    • Plasma 5 alpha-reduced androgens in men and hirsute women: role of adrenals and gonads
    • MEIKLE AW, STRINGHAM JD, WILSON DE, DOLMAN LI, 1979: Plasma 5 alpha-reduced androgens in men and hirsute women: role of adrenals nd gonads. J Clin Endocrinol Metab 48: 969-975.
    • (1979) J Clin Endocrinol Metab , vol.48 , pp. 969-975
    • Meikle, A.W.1    Stringham, J.D.2    Wilson, D.E.3    Dolman, L.I.4
  • 64
    • 0030663220 scopus 로고    scopus 로고
    • Progesterone metabolites and bile acids in serum of patients with intrahepatic cholestasis of pregnancy: effect of ursodeoxycholic acid therapy
    • MENG LJ, REYES H, AXELSON M, PALMA J, HERNANDEZ I, RIBALTA J, SJOVALL J, 1997: Progesterone metabolites and bile acids in serum of patients with intrahepatic cholestasis of pregnancy: effect of ursodeoxycholic acid therapy. Hepatology 26: 1573-1579.
    • (1997) Hepatology , vol.26 , pp. 1573-1579
    • Meng, L.J.1    Reyes, H.2    Axelson, M.3    Palma, J.4    Hernandez, I.5    Ribalta, J.6    Sjovall, J.7
  • 65
    • 0018566098 scopus 로고
    • Pregnanolones, pregnenolone and progesterone in the human feto-placental circulation at term of pregnancy
    • MICKAN H, ZANDER J, 1979: Pregnanolones, pregnenolone and progesterone in the human feto-placental circulation at term of pregnancy. J Steroid iochem 11: 1461-1466.
    • (1979) J Steroid Biochem , vol.11 , pp. 1461-1466
    • Mickan, H.1    Zander, J.2
  • 67
    • 0017806420 scopus 로고
    • Initiation of human parturition IX. Progesterone metabolism by placentas of early and late human gestation
    • MILEWICH L, GANT NF, SCHWARZ BE, CHEN GT, MACDONALD PC, 1978: Initiation of human parturition. IX. Progesterone metabolism by placentas of early and late human gestation. Obstet Gynecol 51: 278-280.
    • (1978) Obstet Gynecol , vol.51 , pp. 278-280
    • Milewich, L.1    Gant, N.F.2    Schwarz, B.E.3    Chen, G.T.4    Macdonald, P.C.5
  • 70
    • 0021325035 scopus 로고
    • Progesterone production by human fetal membranes: an in vitro incubation system for studying hormone production and metabolism
    • MITCHELL BF, POWELL WA, 1984: Progesterone production by human fetal membranes: an in vitro incubation system for studying hormone roduction and metabolism. Am J Obstet Gynecol 148: 303-309.
    • (1984) Am J Obstet Gynecol , vol.148 , pp. 303-309
    • Mitchell, B.F.1    Powell, W.A.2
  • 71
    • 0030670460 scopus 로고    scopus 로고
    • Cell type-specific expression of 17 beta-hydroxysteroid dehydrogenase type 2 in human placenta and fetal liver
    • MOGHRABI N, HEAD JR, ANDERSSON S, 1997: Cell type-specific expression of 17 beta-hydroxysteroid dehydrogenase type 2 in human placenta nd fetal liver. J Clin Endocrinol Metab 82: 3872-3878.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 3872-3878
    • Moghrabi, N.1    Head, J.R.2    Andersson, S.3
  • 72
    • 71249100682 scopus 로고    scopus 로고
    • Plasticity and function of extrasynaptic GABA(A) receptors during pregnancy and after delivery
    • MOSTALLINO MC, SANNA E, CONCAS A, BIGGIO G, FOLLESA P, 2009: Plasticity and function of extrasynaptic GABA(A) receptors during pregnancy and after delivery. Psychoneuroendocrinology 34 (Suppl 1): S74-S83.
    • (2009) Psychoneuroendocrinology , vol.34 , Issue.SUPPL. 1
    • Mostallino, M.C.1    Sanna, E.2    Concas, A.3    Biggio, G.4    Follesa, P.5
  • 73
    • 0022760708 scopus 로고
    • Clinical significance of the feto-placental unit during pregnancy and parturition (in Japanese)
    • NAKAYAMA T, 1986: Clinical significance of the feto-placental unit during pregnancy and parturition (in Japanese). Nippon Sanka Fujinka Gakkai asshi 38: 1173-1183.
    • (1986) Nippon Sanka Fujinka Gakkai Zasshi , vol.38 , pp. 1173-1183
    • Nakayama, T.1
  • 74
    • 0034003544 scopus 로고    scopus 로고
    • Close kinship of human 1; 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes
    • NISHIZAWA M, NAKAJIMA T, YASUDA K, KANZAKI H, SASAGURI Y, WATANABE K, ITO S, 2000: Close kinship of human.1; 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes. Genes Cells 5: 111-125.
    • (2000) Genes Cells , vol.5 , pp. 111-125
    • Nishizawa, M.1    Nakajima, T.2    Yasuda, K.3    Kanzaki, H.4    Sasaguri, Y.5    Watanabe, K.6    Ito, S.7
  • 75
    • 0021265063 scopus 로고
    • Purification and characterization of delta 4-3-ketosteroid 5 beta-reductase
    • OKUDA A, OKUDA K, 1984: Purification and characterization of delta 4-3-ketosteroid 5 beta-reductase. J Biol Chem 259: 7519-7524.
    • (1984) J Biol Chem , vol.259 , pp. 7519-7524
    • Okuda, A.1    Okuda, K.2
  • 77
    • 0033614716 scopus 로고    scopus 로고
    • Sulfated and unsulfated steroids modulate gamma-aminobutyric acidA receptor function through distinct sites
    • PARK-CHUNG M, MALAYEV A, PURDY RH, GIBBS TT, FARB DH, 1999: Sulfated and unsulfated steroids modulate gamma-aminobutyric acidA receptor function through distinct sites. Brain Res 830: 72-87.
    • (1999) Brain Res , vol.830 , pp. 72-87
    • Park-Chung, M.1    Malayev, A.2    Purdy, R.H.3    Gibbs, T.T.4    Farb, D.H.5
  • 78
    • 0031467726 scopus 로고    scopus 로고
    • Distinct sites for inverse modulation of N-methyl-D-aspartate receptors by sulfated steroids
    • PARK-CHUNG M, WU FS, PURDY RH, MALAYEV AA, GIBBS TT, FARB DH, 1997: Distinct sites for inverse modulation of N-methyl-D-aspartate receptors by sulfated steroids. Mol Pharmacol 52: 1113-1123.
    • (1997) Mol Pharmacol , vol.52 , pp. 1113-1123
    • Park-Chung, M.1    Wu, F.S.2    Purdy, R.H.3    Malayev, A.A.4    Gibbs, T.T.5    Farb, D.H.6
  • 79
    • 0035215943 scopus 로고    scopus 로고
    • Neuroactive ring A-reduced metabolites of progesterone in human plasma during pregnancy: elevated levels of 5 alpha-dihydroprogesterone in depressed patients during the latter half of pregnancy
    • PEARSON MURPHY BE, STEINBERG SI, HU FY, ALLISON CM, 2001: Neuroactive ring A-reduced metabolites of progesterone in human plasma during pregnancy: elevated levels of 5 alpha-dihydroprogesterone in depressed patients during the latter half of pregnancy. J Clin Endocrinol Metab 86: 981-5987.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5981-5987
    • Pearson Murphy, B.E.1    Steinberg, S.I.2    Hu, F.Y.3    Allison, C.M.4
  • 80
    • 0032588918 scopus 로고    scopus 로고
    • Two 17beta-hydroxysteroid dehydrogenases (17HSDs) of estradiol biosynthesis: 17HSD type 1 and type 7
    • PELTOKETO H, NOKELAINEN P, PIAO YS, VIHKO R, VIHKO P, 1999: Two 17beta-hydroxysteroid dehydrogenases (17HSDs) of estradiol biosynthesis: 17HSD type 1 and type 7. J Steroid Biochem Mol Biol 69: 431-439.
    • (1999) J Steroid Biochem Mol Biol , vol.69 , pp. 431-439
    • Peltoketo, H.1    Nokelainen, P.2    Piao, Y.S.3    Vihko, R.4    Vihko, P.5
  • 81
    • 0033051603 scopus 로고    scopus 로고
    • Molecular determinants of steroid recognition and catalysis in aldo-keto reductases. Lessons from 3alpha-hydroxysteroid dehydrogenase
    • PENNING TM, 1999: Molecular determinants of steroid recognition and catalysis in aldo-keto reductases. Lessons from 3alpha-hydroxysteroid dehydrogenase. J Steroid Biochem Mol Biol 69: 211-225.
    • (1999) J Steroid Biochem Mol Biol , vol.69 , pp. 211-225
    • Penning, T.M.1
  • 82
    • 0034287545 scopus 로고    scopus 로고
    • Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones
    • PENNING TM, BURCZYNSKI ME, JEZ JM, HUNG CF, LIN HK, MA H, MOORE M, PALACKAL N, RATNAM K, 2000: Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones. Biochem J 351: 67-77.
    • (2000) Biochem J , vol.351 , pp. 67-77
    • Penning, T.M.1    Burczynski, M.E.2    Jez, J.M.3    Hung, C.F.4    Lin, H.K.5    Ma, H.6    Moore, M.7    Palackal, N.8    Ratnam, K.9
  • 86
    • 0035906431 scopus 로고    scopus 로고
    • Influence of 5alpha- and 5beta-reduced progestins on the contractility of isolated human myometrium at term
    • PERUSQUIA M, JASSO-KAMEL J, 2001: Influence of 5alpha- and 5beta-reduced progestins on the contractility of isolated human myometrium at erm. Life Sci 68: 2933-2944.
    • (2001) Life Sci , vol.68 , pp. 2933-2944
    • Perusquia, M.1    Jasso-Kamel, J.2
  • 87
    • 33746154583 scopus 로고    scopus 로고
    • Functions of corticotropin-releasing hormone in anthropoid primates: from brain to placenta
    • POWER ML, SCHULKIN J, 2006: Functions of corticotropin-releasing hormone in anthropoid primates: from brain to placenta. Am J Hum Biol 18: 31-447.
    • (2006) Am J Hum Biol , vol.18 , pp. 431-447
    • Power, M.L.1    Schulkin, J.2
  • 88
    • 0025850517 scopus 로고
    • Inhibition of uterine contractility by progesterone and progesterone metabolites: mediation by progesterone and gamma amino butyric acidA receptor systems
    • PUTNAM CD, BRANN DW, KOLBECK RC, MAHESH VB, 1991: Inhibition of uterine contractility by progesterone and progesterone metabolites: mediation by progesterone and gamma amino butyric acidA receptor systems. Biol Reprod 45: 266-272.
    • (1991) Biol Reprod , vol.45 , pp. 266-272
    • Putnam, C.D.1    Brann, D.W.2    Kolbeck, R.C.3    Mahesh, V.B.4
  • 89
    • 11144343250 scopus 로고    scopus 로고
    • The human fetal adrenal: making adrenal androgens for placental estrogens
    • RAINEY WE, REHMAN KS, CARR BR, 2004: The human fetal adrenal: making adrenal androgens for placental estrogens. Semin Reprod Med 22: 27-336.
    • (2004) Semin Reprod Med , vol.22 , pp. 327-336
    • Rainey, W.E.1    Rehman, K.S.2    Carr, B.R.3
  • 90
    • 0027154163 scopus 로고
    • Changes in the abundance of mRNA for type-I 3 beta-hydroxysteroid dehydrogenase/delta 5-->delta 4 isomerase in the human placenta and fetal membranes during pregnancy and labor
    • RILEY SC, BASSETT NS, BERDUSCO ET, YANG K, LEYSTRA-LANTZ C, LUU-THE V, LABRIE F, CHALLIS JR, 1993: Changes in the abundance of mRNA for type-I 3 beta-hydroxysteroid dehydrogenase/delta 5-->delta 4 isomerase in the human placenta and fetal membranes during pregnancy and labor. Gynecol Obstet Invest 35:. 199-203.
    • (1993) Gynecol Obstet Invest , vol.35 , pp. 199-203
    • Riley, S.C.1    Bassett, N.S.2    Berdusco, E.T.3    Yang, K.4    Leystra-Lantz, C.5    Luu-The, V.6    Labrie, F.7    Challis, J.R.8
  • 91
    • 0026640939 scopus 로고
    • Immunohistochemical localization of 3 beta-hydroxy-5-ene-steroid dehydrogenase/delta 5-->delta 4 isomerase in human placenta and fetal membranes throughout gestation
    • RILEY SC, DUPONT E, WALTON JC, LUU-THE V, LABRIE F, PELLETIER G, CHALLIS JR, 1992: Immunohistochemical localization of 3 beta-hydroxy-5-ene-steroid dehydrogenase/delta 5-->delta 4 isomerase in human placenta and fetal membranes throughout gestation. J Clin Endocrinol Metab 75: 56-961.
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 956-961
    • Riley, S.C.1    Dupont, E.2    Walton, J.C.3    Luu-The, V.4    Labrie, F.5    Pelletier, G.6    Challis, J.R.7
  • 93
    • 0344741467 scopus 로고    scopus 로고
    • Expanded substrate screenings of human and Drosophila type 10 17beta-hydroxysteroid dehydrogenases (HSDs) reveal multiple specificities in bile acid and steroid hormone metabolism: characterization of multifunctional 3alpha/7alpha/7beta/17beta/20beta/21-HSD
    • SHAFQAT N, MARSCHALL HU, FILLING C, NORDLING E, WU XQ, BJORK L, THYBERG J, MARTENSSON E, SALIM S, JORNVALL H, OPPERMANN U, 2003: Expanded substrate screenings of human and Drosophila type 10 17beta-hydroxysteroid dehydrogenases (HSDs) reveal multiple specificities in bile acid and steroid hormone metabolism: characterization of multifunctional 3alpha/7alpha/7beta/17beta/20beta/21-HSD. Biochem J 376: 49-60.
    • (2003) Biochem J , vol.376 , pp. 49-60
    • Shafqat, N.1    Marschall, H.U.2    Filling, C.3    Nordling, E.4    Wu, X.Q.5    Bjork, L.6    Thyberg, J.7    Martensson, E.8    Salim, S.9    Jornvall, H.10    Oppermann, U.11
  • 94
    • 0020056928 scopus 로고
    • Umbilical-cord plasma progesterone in term infants delivered by caesarean section
    • SHAXTED EJ, HEYES VM, WALKER MP, MAYNARD PV, 1982: Umbilical-cord plasma progesterone in term infants delivered by caesarean ection. Br J Obstet Gynaecol 89: 73-76.
    • (1982) Br J Obstet Gynaecol , vol.89 , pp. 73-76
    • Shaxted, E.J.1    Heyes, V.M.2    Walker, M.P.3    Maynard, P.V.4
  • 95
    • 33645356692 scopus 로고    scopus 로고
    • A possible role for progesterone metabolites in human parturition
    • SHEEHAN PM, 2006: A possible role for progesterone metabolites in human parturition. Aust N Z J Obstet Gynaecol 46: 159-163.
    • (2006) Aust N Z J Obstet Gynaecol , vol.46 , pp. 159-163
    • Sheehan, P.M.1
  • 96
    • 24344456508 scopus 로고    scopus 로고
    • 5 Beta-dihydroprogesterone and steroid 5 beta-reductase decrease in association with human parturition at term
    • SHEEHAN PM, RICE GE, MOSES EK, BRENNECKE SP, 2005: 5 Beta-dihydroprogesterone and steroid 5 beta-reductase decrease in association with human parturition at term. Mol Hum Reprod 11: 495-501.
    • (2005) Mol Hum Reprod , vol.11 , pp. 495-501
    • Sheehan, P.M.1    Rice, G.E.2    Moses, E.K.3    Brennecke, S.P.4
  • 97
    • 0032168199 scopus 로고    scopus 로고
    • Sequence of the cDNA of a human dihydrodiol dehydrogenase isoform (AKR1C2) and tissue distribution of its Mrna
    • SHIRAISHI H, ISHIKURA S, MATSUURA K, DEYASHIKI Y, NINOMIYA M, SAKAI S, HARA A, 1998: Sequence of the cDNA of a human dihydrodiol dehydrogenase isoform (AKR1C2) and tissue distribution of its mRNA. Biochem J 334: 399-405.
    • (1998) Biochem J , vol.334 , pp. 399-405
    • Shiraishi, H.1    Ishikura, S.2    Matsuura, K.3    Deyashiki, Y.4    Ninomiya, M.5    Sakai, S.6    Hara, A.7
  • 98
    • 22544488415 scopus 로고    scopus 로고
    • The continuing saga of dehydroepiandrosterone (DHEA)
    • SIITERI PK, 2005: The continuing saga of dehydroepiandrosterone (DHEA). J Clin Endocrinol Metab 90: 3795-3796.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 3795-3796
    • Siiteri, P.K.1
  • 99
    • 24344480466 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone (CRH) and urocortin act through type 1 CRH receptors to stimulate dehydroepiandrosterone sulfate production in human fetal adrenal cells
    • SIRIANNI R, MAYHEW BA, CARR BR, PARKER CR JR, RAINEY WE, 2005: Corticotropin-releasing hormone (CRH) and urocortin act through type 1 CRH receptors to stimulate dehydroepiandrosterone sulfate production in human fetal adrenal cells. J Clin Endocrinol Metab 90: 5393-5400.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 5393-5400
    • Sirianni, R.1    Mayhew, B.A.2    Carr, B.R.3    Parker Jr., C.R.4    Rainey, W.E.5
  • 100
    • 0031758810 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone directly and preferentially stimulates dehydroepiandrosterone sulfate secretion by human fetal adrenal cortical cells
    • SMITH R, MESIANO S, CHAN EC, BROWN S, JAFFE RB, 1998: Corticotropin-releasing hormone directly and preferentially stimulates dehydroepiandrosterone sulfate secretion by human fetal adrenal cortical cells. J Clin Endocrinol Metab 83: 2916-2920.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2916-2920
    • Smith, R.1    Mesiano, S.2    Chan, E.C.3    Brown, S.4    Jaffe, R.B.5
  • 102
    • 1642305724 scopus 로고    scopus 로고
    • Human cytosolic 3alphahydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3betahydroxysteroid dehydrogenase activity: implications for steroid hormone metabolism and action
    • STECKELBROECK S, JIN Y, GOPISHETTY S, OYESANMI B, PENNING TM, 2004: Human cytosolic 3alphahydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3betahydroxysteroid dehydrogenase activity: implications for steroid hormone metabolism and action. J iol Chem 279: 10784-10795.
    • (2004) J Biol Chem , vol.279 , pp. 10784-10795
    • Steckelbroeck, S.1    Jin, Y.2    Gopishetty, S.3    Oyesanmi, B.4    Penning, T.M.5
  • 103
    • 0016591263 scopus 로고
    • Identification and quantitation of 5alpha-pregnanedione in human pregnancy plasma
    • STOA KF, BESSESEN A, 1975: Identification and quantitation of 5alpha-pregnanedione in human pregnancy plasma. J Steroid Biochem 6: 21-25.
    • (1975) J Steroid Biochem , vol.6 , pp. 21-25
    • Stoa, K.F.1    Bessesen, A.2
  • 104
    • 0031596231 scopus 로고    scopus 로고
    • 17Beta-hydroxysteroid dehydrogenase types 1 and 2 in human placenta: an immunohistochemical study with correlation to placental development
    • TAKEYAMA J, SASANO H, SUZUKI T, IINUMA K, NAGURA H, ANDERSSON S, 1998: 17Beta-hydroxysteroid dehydrogenase types 1 and 2 in human placenta: an immunohistochemical study with correlation to placental development. J Clin Endocrinol Metab 83: 3710-3715.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3710-3715
    • Takeyama, J.1    Sasano, H.2    Suzuki, T.3    Iinuma, K.4    Nagura, H.5    Andersson, S.6
  • 107
    • 33645852277 scopus 로고    scopus 로고
    • Tolerance development to Morris water maze test impairments induced by acute allopregnanolone
    • TURKMEN S, LOFGREN M, BIRZNIECE V, BACKSTROM T, JOHANSSON IM, 2006: Tolerance development to Morris water maze test impairments induced by acute allopregnanolone. Neuroscience 139: 651-659.
    • (2006) Neuroscience , vol.139 , pp. 651-659
    • Turkmen, S.1    Lofgren, M.2    Birzniece, V.3    Backstrom, T.4    Johansson, I.M.5
  • 108
    • 0015978361 scopus 로고
    • Significant fall in progesterone and rise in oestradiol levels in human peripheral plasma before onset of labour
    • TURNBULL AC, PATTEN PT, FLINT AP, KEIRSE MJ, JEREMY JY, ANDERSON AB, 1974: Significant fall in progesterone and rise in oestradiol levels in human peripheral plasma before onset of labour. Lancet 1: 101-103.
    • (1974) Lancet , vol.1 , pp. 101-103
    • Turnbull, A.C.1    Patten, P.T.2    Flint, A.P.3    Keirse, M.J.4    Jeremy, J.Y.5    Anderson, A.B.6
  • 109
    • 0036547847 scopus 로고    scopus 로고
    • Substrate specificity of human 3(20)alpha-hydroxysteroid dehydrogenase for neurosteroids and its inhibition by benzodiazepines
    • USAMI N, YAMAMOTO T, SHINTANI S, ISHIKURA S, HIGAKI Y, KATAGIRI Y, HARA A, 2002: Substrate specificity of human 3(20)alpha-hydroxysteroid dehydrogenase for neurosteroids and its inhibition by benzodiazepines. Biol Pharm Bull 25: 441-445.
    • (2002) Biol Pharm Bull , vol.25 , pp. 441-445
    • Usami, N.1    Yamamoto, T.2    Shintani, S.3    Ishikura, S.4    Higaki, Y.5    Katagiri, Y.6    Hara, A.7
  • 110
    • 65349135475 scopus 로고    scopus 로고
    • Changes in human placental 5alpha-reductase isoenzyme expression with advancing gestation: effects of fetal sex and glucocorticoid exposure
    • VU TT, HIRST JJ, STARK M, WRIGHT IM, PALLISER HK, HODYL N, CLIFTON VL, 2009: Changes in human placental 5alpha-reductase isoenzyme expression with advancing gestation: effects of fetal sex and glucocorticoid exposure. Reprod Fertil Dev 21: 599-607.
    • (2009) Reprod Fertil Dev , vol.21 , pp. 599-607
    • Vu, T.T.1    Hirst, J.J.2    Stark, M.3    Wright, I.M.4    Palliser, H.K.5    Hodyl, N.6    Clifton, V.L.7
  • 111
    • 0023837339 scopus 로고
    • Progesterone and estradiol production by normal and preeclamptic placentas
    • WALSH SW, 1988: Progesterone and estradiol production by normal and preeclamptic placentas. Obstet Gynecol 71: 222-226.
    • (1988) Obstet Gynecol , vol.71 , pp. 222-226
    • Walsh, S.W.1
  • 112
    • 0025290776 scopus 로고
    • Effects of DHA-S on placental 3 beta-hydroxysteroid dehydrogenase activity, progesterone and 20 alphadihydroprogesterone concentrations in placenta and serum
    • WATANABE H, HIRATO K, HASHINO M, KOSAKI T, KIMURA T, NAKAYAMA T, YANAIHARA T, 1990: Effects of DHA-S on placental 3 beta-hydroxysteroid dehydrogenase activity, progesterone and. 20 alphadihydroprogesterone concentrations in placenta and serum. Endocrinol Jpn 37: 69-77.
    • (1990) Endocrinol Jpn , vol.37 , pp. 69-77
    • Watanabe, H.1    Hirato, K.2    Hashino, M.3    Kosaki, T.4    Kimura, T.5    Nakayama, T.6    Yanaihara, T.7
  • 113
    • 0034089646 scopus 로고    scopus 로고
    • Geometry and charge determine pharmacological effects of steroids on N-methyl-D-aspartate receptor-induced Ca(2+) accumulation and cell death
    • WEAVER CE, LAND MB, PURDY RH, RICHARDS KG, GIBBS TT, FARB DH, 2000: Geometry and charge determine pharmacological effects of steroids on N-methyl-D-aspartate receptor-induced Ca(2+) accumulation and cell death. J Pharmacol Exp Ther 293: 747-754.
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 747-754
    • Weaver, C.E.1    Land, M.B.2    Purdy, R.H.3    Richards, K.G.4    Gibbs, T.T.5    Farb, D.H.6
  • 114
    • 70149108055 scopus 로고    scopus 로고
    • Role of neurosteroids in regulating cell death and proliferation in the late gestation fetal brain
    • YAWNO T, HIRST JJ, CASTILLO-MELENDEZ M, WALKER DW, 2009: Role of neurosteroids in regulating cell death and proliferation in the late estation fetal brain. Neuroscience 163: 838-847.
    • (2009) Neuroscience , vol.163 , pp. 838-847
    • Yawno, T.1    Hirst, J.J.2    Castillo-Melendez, M.3    Walker, D.W.4
  • 115
    • 24044433541 scopus 로고    scopus 로고
    • A neuroactive steroid, allotetrahydrocorticosterone inhibits sensory nerves activation in guinea-pig airways
    • YOSHIHARA S, MORIMOTO H, OHORI M, YAMADA Y, ABE T, ARISAKA O, 2005: A neuroactive steroid, allotetrahydrocorticosterone inhibits sensory nerves activation in guinea-pig airways. Neurosci Res 53: 210-215.
    • (2005) Neurosci Res , vol.53 , pp. 210-215
    • Yoshihara, S.1    Morimoto, H.2    Ohori, M.3    Yamada, Y.4    Abe, T.5    Arisaka, O.6


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