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Volumn 52, Issue 2, 2008, Pages 117-123

Application of Metabolomics to Cardiovascular Biomarker and Pathway Discovery

Author keywords

biomarkers; metabolomics; prognosis

Indexed keywords

AMINO ACID; BIOLOGICAL MARKER; CARBOXYLIC ACID; LIPID; NUCLEOTIDE; SUGAR;

EID: 45849145091     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2008.03.043     Document Type: Review
Times cited : (193)

References (39)
  • 1
    • 0015131404 scopus 로고
    • Quantitative analysis of urine vapor and breath by gas-liquid partition chromatography
    • Pauling L., Robinson A.B., Teranishi R., and Cary P. Quantitative analysis of urine vapor and breath by gas-liquid partition chromatography. Proc Natl Acad Sci U S A 68 (1971) 2374-2376
    • (1971) Proc Natl Acad Sci U S A , vol.68 , pp. 2374-2376
    • Pauling, L.1    Robinson, A.B.2    Teranishi, R.3    Cary, P.4
  • 2
    • 0015111451 scopus 로고
    • Metabolic profiles: gas-phase methods for analysis of metabolites
    • Horning E.C., and Horning M.G. Metabolic profiles: gas-phase methods for analysis of metabolites. Clin Chem 17 (1971) 802-809
    • (1971) Clin Chem , vol.17 , pp. 802-809
    • Horning, E.C.1    Horning, M.G.2
  • 3
    • 0032694577 scopus 로고    scopus 로고
    • "Metabonomics": understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
    • Nicholson J.K., Lindon J.C., and Holmes E. "Metabonomics": understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 29 (1999) 1181-1189
    • (1999) Xenobiotica , vol.29 , pp. 1181-1189
    • Nicholson, J.K.1    Lindon, J.C.2    Holmes, E.3
  • 4
    • 0035160371 scopus 로고    scopus 로고
    • A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations
    • Raamsdonk L.M., Teusink B., Broadhurst D., et al. A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations. Nat Biotechnol 19 (2001) 45-50
    • (2001) Nat Biotechnol , vol.19 , pp. 45-50
    • Raamsdonk, L.M.1    Teusink, B.2    Broadhurst, D.3
  • 5
    • 0038699591 scopus 로고    scopus 로고
    • High-throughput classification of yeast mutants for functional genomics using metabolic footprinting
    • Allen J., Davey H.M., Broadhurst D., et al. High-throughput classification of yeast mutants for functional genomics using metabolic footprinting. Nat Biotechnol 21 (2003) 692-696
    • (2003) Nat Biotechnol , vol.21 , pp. 692-696
    • Allen, J.1    Davey, H.M.2    Broadhurst, D.3
  • 6
    • 2342509057 scopus 로고    scopus 로고
    • Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance
    • An J., Muoio D.M., Shiota M., et al. Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance. Nat Med 10 (2004) 268-274
    • (2004) Nat Med , vol.10 , pp. 268-274
    • An, J.1    Muoio, D.M.2    Shiota, M.3
  • 7
    • 0022551590 scopus 로고
    • Identification of 3-methylglutarylcarnitine. A new diagnostic metabolite of 3-hydroxy-3-methylglutaryl-coenzyme A lyase deficiency
    • Roe C.R., Millington D.S., and Maltby D.A. Identification of 3-methylglutarylcarnitine. A new diagnostic metabolite of 3-hydroxy-3-methylglutaryl-coenzyme A lyase deficiency. J Clin Invest 77 (1986) 1391-1394
    • (1986) J Clin Invest , vol.77 , pp. 1391-1394
    • Roe, C.R.1    Millington, D.S.2    Maltby, D.A.3
  • 8
    • 33645668108 scopus 로고    scopus 로고
    • The tandem mass spectrometry newborn screening experience in North Carolina: 1997-2005
    • Frazier D.M., Millington D.S., McCandless S.E., et al. The tandem mass spectrometry newborn screening experience in North Carolina: 1997-2005. J Inherit Metab Dis 29 (2006) 76-85
    • (2006) J Inherit Metab Dis , vol.29 , pp. 76-85
    • Frazier, D.M.1    Millington, D.S.2    McCandless, S.E.3
  • 12
    • 18844406001 scopus 로고    scopus 로고
    • Measuring the metabolome: current analytical technologies
    • Dunn W.B., Bailey N.J., and Johnson H.E. Measuring the metabolome: current analytical technologies. Analyst 130 (2005) 606-625
    • (2005) Analyst , vol.130 , pp. 606-625
    • Dunn, W.B.1    Bailey, N.J.2    Johnson, H.E.3
  • 13
    • 16244402990 scopus 로고    scopus 로고
    • Metabolomics: current analytical platforms and methodologies
    • Dunn W.B., and Ellis D. Metabolomics: current analytical platforms and methodologies. Trends Anal Chem 4 (2005) 285-294
    • (2005) Trends Anal Chem , vol.4 , pp. 285-294
    • Dunn, W.B.1    Ellis, D.2
  • 14
    • 33745361258 scopus 로고    scopus 로고
    • Metabonomics techniques and applications to pharmaceutical research and development
    • Lindon J.C., Holmes E., and Nicholson J.K. Metabonomics techniques and applications to pharmaceutical research and development. Pharm Res 23 (2006) 1075-1088
    • (2006) Pharm Res , vol.23 , pp. 1075-1088
    • Lindon, J.C.1    Holmes, E.2    Nicholson, J.K.3
  • 15
    • 0037372429 scopus 로고    scopus 로고
    • Cardiac outflow of amino acids and purines during myocardial ischemia and reperfusion
    • Backstrom T., Goiny M., Lockowandt U., Liska J., and Franco-Cereceda A. Cardiac outflow of amino acids and purines during myocardial ischemia and reperfusion. J Appl Physiol 94 (2003) 1122-1128
    • (2003) J Appl Physiol , vol.94 , pp. 1122-1128
    • Backstrom, T.1    Goiny, M.2    Lockowandt, U.3    Liska, J.4    Franco-Cereceda, A.5
  • 16
    • 0029948194 scopus 로고    scopus 로고
    • Simultaneous determination of adenosine, inosine, hypoxanthine, xanthine, and uric acid in microdialysis samples using microbore column high-performance liquid chromatography with a diode array detector
    • Mei D.A., Gross G.J., and Nithipatikom K. Simultaneous determination of adenosine, inosine, hypoxanthine, xanthine, and uric acid in microdialysis samples using microbore column high-performance liquid chromatography with a diode array detector. Anal Biochem 238 (1996) 34-39
    • (1996) Anal Biochem , vol.238 , pp. 34-39
    • Mei, D.A.1    Gross, G.J.2    Nithipatikom, K.3
  • 17
    • 0035260176 scopus 로고    scopus 로고
    • Energy-related metabolites during and after induced myocardial infarction with special emphasis on the reperfusion injury after extracorporeal circulation
    • Zemgulis V., Ronquist G., Bjerner T., et al. Energy-related metabolites during and after induced myocardial infarction with special emphasis on the reperfusion injury after extracorporeal circulation. Acta Physiol Scand 171 (2001) 129-143
    • (2001) Acta Physiol Scand , vol.171 , pp. 129-143
    • Zemgulis, V.1    Ronquist, G.2    Bjerner, T.3
  • 18
    • 2642686624 scopus 로고    scopus 로고
    • Correlation of high-resolution magic angle spinning proton magnetic resonance spectroscopy with histopathology of intact human brain tumor specimens
    • Cheng L.L., Chang I.W., Louis D.N., and Gonzalez R.G. Correlation of high-resolution magic angle spinning proton magnetic resonance spectroscopy with histopathology of intact human brain tumor specimens. Cancer Res 58 (1998) 1825-1832
    • (1998) Cancer Res , vol.58 , pp. 1825-1832
    • Cheng, L.L.1    Chang, I.W.2    Louis, D.N.3    Gonzalez, R.G.4
  • 19
    • 34248545254 scopus 로고    scopus 로고
    • Mass spectrometry-based "omics" technologies in cancer diagnostics
    • Zhang X., Wei D., Yap Y., Li L., Guo S., and Chen F. Mass spectrometry-based "omics" technologies in cancer diagnostics. Mass Spectrom Rev 26 (2007) 403-431
    • (2007) Mass Spectrom Rev , vol.26 , pp. 403-431
    • Zhang, X.1    Wei, D.2    Yap, Y.3    Li, L.4    Guo, S.5    Chen, F.6
  • 21
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • Storey J.D., and Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci U S A 100 (2003) 9440-9445
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9440-9445
    • Storey, J.D.1    Tibshirani, R.2
  • 23
    • 0038054341 scopus 로고    scopus 로고
    • PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
    • Mootha V.K., Lindgren C.M., Eriksson K.F., et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 34 (2003) 267-273
    • (2003) Nat Genet , vol.34 , pp. 267-273
    • Mootha, V.K.1    Lindgren, C.M.2    Eriksson, K.F.3
  • 28
    • 33745599103 scopus 로고    scopus 로고
    • Mapping a plant's chemical vocabulary
    • Baxter I.R., and Borevitz J.O. Mapping a plant's chemical vocabulary. Nat Genet 38 (2006) 737-738
    • (2006) Nat Genet , vol.38 , pp. 737-738
    • Baxter, I.R.1    Borevitz, J.O.2
  • 29
    • 20544445469 scopus 로고    scopus 로고
    • High-throughput metabolic state analysis: the missing link in integrated functional genomics of yeasts
    • Villas-Boas S.G., Moxley J.F., Akesson M., Stephanopoulos G., and Nielsen J. High-throughput metabolic state analysis: the missing link in integrated functional genomics of yeasts. Biochem J 388 (2005) 669-677
    • (2005) Biochem J , vol.388 , pp. 669-677
    • Villas-Boas, S.G.1    Moxley, J.F.2    Akesson, M.3    Stephanopoulos, G.4    Nielsen, J.5
  • 30
    • 0034036980 scopus 로고    scopus 로고
    • Anaplerosis of the citric acid cycle: role in energy metabolism of heart and skeletal muscle
    • Gibala M.J., Young M.E., and Taegtmeyer H. Anaplerosis of the citric acid cycle: role in energy metabolism of heart and skeletal muscle. Acta Physiol Scand 168 (2000) 657-665
    • (2000) Acta Physiol Scand , vol.168 , pp. 657-665
    • Gibala, M.J.1    Young, M.E.2    Taegtmeyer, H.3
  • 31
    • 5644268986 scopus 로고    scopus 로고
    • Zonation of labeling of lipogenic acetyl-CoA across the liver: implications for studies of lipogenesis by mass isotopomer analysis
    • Bederman I.R., Reszko A.E., Kasumov T., et al. Zonation of labeling of lipogenic acetyl-CoA across the liver: implications for studies of lipogenesis by mass isotopomer analysis. J Biol Chem 279 (2004) 43207-43216
    • (2004) J Biol Chem , vol.279 , pp. 43207-43216
    • Bederman, I.R.1    Reszko, A.E.2    Kasumov, T.3
  • 32
    • 2442649129 scopus 로고    scopus 로고
    • Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors
    • He W., Miao F.J., Lin D.C., et al. Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors. Nature 429 (2004) 188-193
    • (2004) Nature , vol.429 , pp. 188-193
    • He, W.1    Miao, F.J.2    Lin, D.C.3
  • 33
    • 33744984371 scopus 로고    scopus 로고
    • Proton NMR analysis of plasma is a weak predictor of coronary artery disease
    • Kirschenlohr H.L., Griffin J.L., Clarke S.C., et al. Proton NMR analysis of plasma is a weak predictor of coronary artery disease. Nat Med 12 (2006) 705-710
    • (2006) Nat Med , vol.12 , pp. 705-710
    • Kirschenlohr, H.L.1    Griffin, J.L.2    Clarke, S.C.3
  • 34
    • 33644874718 scopus 로고    scopus 로고
    • Metabolomic identification of novel biomarkers of myocardial ischemia
    • Sabatine M.S., Liu E., Morrow D.A., et al. Metabolomic identification of novel biomarkers of myocardial ischemia. Circulation 112 (2005) 3868-3875
    • (2005) Circulation , vol.112 , pp. 3868-3875
    • Sabatine, M.S.1    Liu, E.2    Morrow, D.A.3
  • 35
    • 3242678739 scopus 로고    scopus 로고
    • Effect of endurance training on muscle TCA cycle metabolism during exercise in humans
    • Howarth K.R., LeBlanc P.J., Heigenhauser G.J., and Gibala M.J. Effect of endurance training on muscle TCA cycle metabolism during exercise in humans. J Appl Physiol 97 (2004) 579-584
    • (2004) J Appl Physiol , vol.97 , pp. 579-584
    • Howarth, K.R.1    LeBlanc, P.J.2    Heigenhauser, G.J.3    Gibala, M.J.4
  • 36
    • 38349100117 scopus 로고    scopus 로고
    • Combined metabolomic and proteomic analysis of human atrial fibrillation
    • Mayr M., Yusuf S., Weir G., et al. Combined metabolomic and proteomic analysis of human atrial fibrillation. J Am Coll Cardiol 51 (2008) 585-594
    • (2008) J Am Coll Cardiol , vol.51 , pp. 585-594
    • Mayr, M.1    Yusuf, S.2    Weir, G.3
  • 37
    • 34547623750 scopus 로고    scopus 로고
    • Genomewide association analysis of coronary artery disease
    • Samani N.J., Erdmann J., Hall A.S., et al. Genomewide association analysis of coronary artery disease. N Engl J Med 357 (2007) 443-453
    • (2007) N Engl J Med , vol.357 , pp. 443-453
    • Samani, N.J.1    Erdmann, J.2    Hall, A.S.3
  • 38
    • 34249996115 scopus 로고    scopus 로고
    • A common allele on chromosome 9 associated with coronary heart disease
    • McPherson R., Pertsemlidis A., Kavaslar N., et al. A common allele on chromosome 9 associated with coronary heart disease. Science 316 (2007) 1488-1491
    • (2007) Science , vol.316 , pp. 1488-1491
    • McPherson, R.1    Pertsemlidis, A.2    Kavaslar, N.3
  • 39
    • 34250010480 scopus 로고    scopus 로고
    • A common variant on chromosome 9p21 affects the risk of myocardial infarction
    • Helgadottir A., Thorleifsson G., Manolescu A., et al. A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science 316 (2007) 1491-1493
    • (2007) Science , vol.316 , pp. 1491-1493
    • Helgadottir, A.1    Thorleifsson, G.2    Manolescu, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.