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Volumn 23, Issue 7, 2012, Pages 699-705

Resveratrol up-regulates SIRT1 and inhibits cellular oxidative stress in the diabetic milieu: Mechanistic insights

Author keywords

FOXO3a; Oxidative stress; P47phox; Resveratrol and diabetes; SIRT1

Indexed keywords

MANNITOL; PROTEIN P47; REACTIVE OXYGEN METABOLITE; RESVERATROL; SIRTUIN 1; SMALL INTERFERING RNA; SUPEROXIDE; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR FOXO;

EID: 84862306635     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2011.03.012     Document Type: Article
Times cited : (109)

References (72)
  • 1
    • 0036902972 scopus 로고    scopus 로고
    • Oxidative stress, inflammation, and diabetic vasculopathies: the role of alpha tocopherol therapy
    • Jialal I., Devaraj S., Venugopal S.K. Oxidative stress, inflammation, and diabetic vasculopathies: the role of alpha tocopherol therapy. Free Radic Res 2002, 6:1331-1336.
    • (2002) Free Radic Res , vol.6 , pp. 1331-1336
    • Jialal, I.1    Devaraj, S.2    Venugopal, S.K.3
  • 2
    • 0842264588 scopus 로고    scopus 로고
    • Elevated blood interleukin-6 levels in hyperketonemic type 1 diabetic patients and secretion by acetoacetate-treated cultured U937 monocytes
    • Jain S.K., Kannan K., Lim G., Matthew-Greer J., McVie R., Bocchini J.A. Elevated blood interleukin-6 levels in hyperketonemic type 1 diabetic patients and secretion by acetoacetate-treated cultured U937 monocytes. Diabetes Care 2003, 26:2139-2143.
    • (2003) Diabetes Care , vol.26 , pp. 2139-2143
    • Jain, S.K.1    Kannan, K.2    Lim, G.3    Matthew-Greer, J.4    McVie, R.5    Bocchini, J.A.6
  • 3
    • 0042393597 scopus 로고    scopus 로고
    • High-glucose-induced expression of proinflammatory cytokine and chemokine genes in monocytic cells
    • Shanmugam N., Reddy M.A., Guha M., Natarajan R. High-glucose-induced expression of proinflammatory cytokine and chemokine genes in monocytic cells. Diabetes 2003, 52:1256-1264.
    • (2003) Diabetes , vol.52 , pp. 1256-1264
    • Shanmugam, N.1    Reddy, M.A.2    Guha, M.3    Natarajan, R.4
  • 4
    • 0032921465 scopus 로고    scopus 로고
    • Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways
    • Igarashi M., Wakasaki H., Takahara N., Ishii H., Jiang Z.Y., Yamauchi T., et al. Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways. J Clin Invest 1999, 103:185-195.
    • (1999) J Clin Invest , vol.103 , pp. 185-195
    • Igarashi, M.1    Wakasaki, H.2    Takahara, N.3    Ishii, H.4    Jiang, Z.Y.5    Yamauchi, T.6
  • 5
    • 0345346385 scopus 로고    scopus 로고
    • Protein kinase C activity is acutely regulated by plasma glucose concentration in human monocytes in vivo
    • Ceolotto G., Gallo A., Miola M., Sartori M., Trevisan R., Prato S.D., et al. Protein kinase C activity is acutely regulated by plasma glucose concentration in human monocytes in vivo. Diabetes 1999, 48:1316-1322.
    • (1999) Diabetes , vol.48 , pp. 1316-1322
    • Ceolotto, G.1    Gallo, A.2    Miola, M.3    Sartori, M.4    Trevisan, R.5    Prato, S.D.6
  • 6
    • 33846931618 scopus 로고    scopus 로고
    • Proinflammatory effects of glucose and anti-inflammatory effect of insulin: relevance to cardiovascular disease
    • Dandona P., Chaudhuri A., Ghanim H., Mohanty P. Proinflammatory effects of glucose and anti-inflammatory effect of insulin: relevance to cardiovascular disease. Am J Cardiol 2007, 99:15B-26B.
    • (2007) Am J Cardiol , vol.99
    • Dandona, P.1    Chaudhuri, A.2    Ghanim, H.3    Mohanty, P.4
  • 8
    • 42449109476 scopus 로고    scopus 로고
    • Mechanisms of disease: advanced glycation end-products and their receptor in inflammation and diabetes complications
    • Yan S.F., Ramasamy R., Schmidt A.M. Mechanisms of disease: advanced glycation end-products and their receptor in inflammation and diabetes complications. Nat Clin Pract Endocrinol Metab 2008, 4:285-293.
    • (2008) Nat Clin Pract Endocrinol Metab , vol.4 , pp. 285-293
    • Yan, S.F.1    Ramasamy, R.2    Schmidt, A.M.3
  • 9
    • 12144255424 scopus 로고    scopus 로고
    • Hyperglycemia induces monocytic release of interleukin-6 via induction of protein kinase C-alpha and beta
    • Devaraj S., Venugopal S.K., Singh U., Jialal I. Hyperglycemia induces monocytic release of interleukin-6 via induction of protein kinase C-alpha and beta. Diabetes 2005, 54:85-91.
    • (2005) Diabetes , vol.54 , pp. 85-91
    • Devaraj, S.1    Venugopal, S.K.2    Singh, U.3    Jialal, I.4
  • 10
    • 0031916984 scopus 로고    scopus 로고
    • The free radical theory of aging matures
    • Beckman K.B., Ames B.N. The free radical theory of aging matures. Physiol Rev 1998, 78:547-581.
    • (1998) Physiol Rev , vol.78 , pp. 547-581
    • Beckman, K.B.1    Ames, B.N.2
  • 11
    • 0036787465 scopus 로고    scopus 로고
    • α-Tocopherol decreases superoxide anion release in human monocytes under hyperglycemic conditions via inhibition of protein kinase C-α.
    • Venugopal S.K., Devaraj S., Yang T., Jialal I. α-Tocopherol decreases superoxide anion release in human monocytes under hyperglycemic conditions via inhibition of protein kinase C-α. Diabetes. 2002, 51(10):3049-3054.
    • (2002) Diabetes. , vol.51 , Issue.10 , pp. 3049-3054
    • Venugopal, S.K.1    Devaraj, S.2    Yang, T.3    Jialal, I.4
  • 12
    • 33746228121 scopus 로고    scopus 로고
    • Sirtuins in aging and age-related disease
    • Longo V.D., Kennedy B.K. Sirtuins in aging and age-related disease. Cell 2006, 126:257-268.
    • (2006) Cell , vol.126 , pp. 257-268
    • Longo, V.D.1    Kennedy, B.K.2
  • 13
    • 10644277123 scopus 로고    scopus 로고
    • Structure and chemistry of the Sir2 family of NAD+-dependent histone/protein deactylases
    • Marmorstein R. Structure and chemistry of the Sir2 family of NAD+-dependent histone/protein deactylases. Biochem Soc Trans 2004, 32:904-909.
    • (2004) Biochem Soc Trans , vol.32 , pp. 904-909
    • Marmorstein, R.1
  • 14
    • 34249083199 scopus 로고    scopus 로고
    • Sirtuins in mammals: insights into their biological function
    • Michan S., Sinclair D. Sirtuins in mammals: insights into their biological function. Biochem J 2007, 404:1-13.
    • (2007) Biochem J , vol.404 , pp. 1-13
    • Michan, S.1    Sinclair, D.2
  • 16
    • 33751113602 scopus 로고    scopus 로고
    • Mammalian sirtuins-emerging roles in physiology, aging, and calorie restriction
    • Haigis M.C., Guarente L.P. Mammalian sirtuins-emerging roles in physiology, aging, and calorie restriction. Genes Dev 2006, 20:2913-2921.
    • (2006) Genes Dev , vol.20 , pp. 2913-2921
    • Haigis, M.C.1    Guarente, L.P.2
  • 17
    • 33744480316 scopus 로고    scopus 로고
    • NAD+and NADH in cellular functions and cell death
    • Ying W. NAD+and NADH in cellular functions and cell death. Front Biosci 2006, 11:3129-3148.
    • (2006) Front Biosci , vol.11 , pp. 3129-3148
    • Ying, W.1
  • 18
    • 0141814680 scopus 로고    scopus 로고
    • Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
    • Cheng H.L., Mostoslavsky R., Saito S., Manis J.P., Gu Y., Patel P., et al. Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci USA 2003, 100:10794-10799.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10794-10799
    • Cheng, H.L.1    Mostoslavsky, R.2    Saito, S.3    Manis, J.P.4    Gu, Y.5    Patel, P.6
  • 19
    • 0037093346 scopus 로고    scopus 로고
    • Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
    • Langley E., Pearson M., Faretta M., Bauer U.M., Frye R.A., Minucci S., et al. Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence. EMBO J. 2002, 21:2383-2396.
    • (2002) EMBO J. , vol.21 , pp. 2383-2396
    • Langley, E.1    Pearson, M.2    Faretta, M.3    Bauer, U.M.4    Frye, R.A.5    Minucci, S.6
  • 20
    • 0035913911 scopus 로고    scopus 로고
    • Negative control of p53 by Sir2alpha promotes cell survival under stress
    • Luo J., Nikolaev A.Y., Imai S., Chen D., Su F., Shiloh A., et al. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 2001, 19:137-148.
    • (2001) Cell , vol.19 , pp. 137-148
    • Luo, J.1    Nikolaev, A.Y.2    Imai, S.3    Chen, D.4    Su, F.5    Shiloh, A.6
  • 22
    • 12144290563 scopus 로고    scopus 로고
    • Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
    • Brunet A., Sweeney L.B., Sturgill J.F., Chua K.F., Greer P.L., Lin Y., et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 2004, 303:2011-2015.
    • (2004) Science , vol.303 , pp. 2011-2015
    • Brunet, A.1    Sweeney, L.B.2    Sturgill, J.F.3    Chua, K.F.4    Greer, P.L.5    Lin, Y.6
  • 23
    • 20144365700 scopus 로고    scopus 로고
    • Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes
    • Frescas D., Valenti L., Accili D. Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes. J Biol Chem 2005, 280:20589-20595.
    • (2005) J Biol Chem , vol.280 , pp. 20589-20595
    • Frescas, D.1    Valenti, L.2    Accili, D.3
  • 24
    • 24744469490 scopus 로고    scopus 로고
    • SIRT1 is critical regulator of FOXO-mediated transcription in response to oxidative stress
    • Kobayashi Y., Furukawa-Hibi Y., Chen C., Horio Y., Isobe K., Ikeda K., et al. SIRT1 is critical regulator of FOXO-mediated transcription in response to oxidative stress. Int J Mol Med 2005, 16:237-243.
    • (2005) Int J Mol Med , vol.16 , pp. 237-243
    • Kobayashi, Y.1    Furukawa-Hibi, Y.2    Chen, C.3    Horio, Y.4    Isobe, K.5    Ikeda, K.6
  • 25
    • 0036204123 scopus 로고    scopus 로고
    • Signaling on telomerase: a master switch in cell aging and immortalization
    • Li H., Liu J.P. Signaling on telomerase: a master switch in cell aging and immortalization. Biogerontology 2002, 3:107-116.
    • (2002) Biogerontology , vol.3 , pp. 107-116
    • Li, H.1    Liu, J.P.2
  • 26
    • 16344384026 scopus 로고    scopus 로고
    • Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation
    • Yang Y., Hou H., Haller E.M., Nicosia S.V., Bai W. Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation. EMBO J 2005, 24:1021-1032.
    • (2005) EMBO J , vol.24 , pp. 1021-1032
    • Yang, Y.1    Hou, H.2    Haller, E.M.3    Nicosia, S.V.4    Bai, W.5
  • 28
    • 1342264308 scopus 로고    scopus 로고
    • Mammalian SIRT1 represses forkhead transcription factors
    • Motta M.C., Divecha N., Lemieux M., Kamel C., Chen D., Gu W., et al. Mammalian SIRT1 represses forkhead transcription factors. Cell 2004, 116:551-563.
    • (2004) Cell , vol.116 , pp. 551-563
    • Motta, M.C.1    Divecha, N.2    Lemieux, M.3    Kamel, C.4    Chen, D.5    Gu, W.6
  • 29
    • 34247570492 scopus 로고    scopus 로고
    • Strong expression of a longevity-related protein, SIRT1, in Bowen's disease
    • Hida Y., Kubo Y., Murao K., Arase S. Strong expression of a longevity-related protein, SIRT1, in Bowen's disease. Arch Dermatol Res 2007, 299:103-106.
    • (2007) Arch Dermatol Res , vol.299 , pp. 103-106
    • Hida, Y.1    Kubo, Y.2    Murao, K.3    Arase, S.4
  • 30
    • 33847091642 scopus 로고    scopus 로고
    • Intermittent fasting prevents the progression of type I diabetic nephropathy in rats and changes the expression of Sir2 and p53
    • Tikoo K., Tripathi D.N., Kabra D.G., Sharma V., Gaikwad A.B. Intermittent fasting prevents the progression of type I diabetic nephropathy in rats and changes the expression of Sir2 and p53. FEBS Lett 2007, 581:1071-1078.
    • (2007) FEBS Lett , vol.581 , pp. 1071-1078
    • Tikoo, K.1    Tripathi, D.N.2    Kabra, D.G.3    Sharma, V.4    Gaikwad, A.B.5
  • 31
    • 34447308268 scopus 로고    scopus 로고
    • SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
    • Kim D., Nguyen M.D., Dobbin M.M., Fischer A., Sananbenesi F., Rodgers J.T., et al. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J 2007, 26:3169-3179.
    • (2007) EMBO J , vol.26 , pp. 3169-3179
    • Kim, D.1    Nguyen, M.D.2    Dobbin, M.M.3    Fischer, A.4    Sananbenesi, F.5    Rodgers, J.T.6
  • 32
    • 34547101692 scopus 로고    scopus 로고
    • The expression of SIRT1 in nonalcoholic fatty liver disease induced by high-fat diet in rats
    • Deng X.Q., Chen L.L., Li N.X. The expression of SIRT1 in nonalcoholic fatty liver disease induced by high-fat diet in rats. Liver Int 2007, 27:708-715.
    • (2007) Liver Int , vol.27 , pp. 708-715
    • Deng, X.Q.1    Chen, L.L.2    Li, N.X.3
  • 33
    • 77951174682 scopus 로고    scopus 로고
    • Downregulation of the longevity-associated protein sirtuin 1 in insulin resistance and metabolic syndrome: potential biochemical mechanisms
    • de Kreutzenberg S.V., Ceolotto G., Papparella I., Bortoluzzi A., Semplicini A., Dalla Man C., et al. Downregulation of the longevity-associated protein sirtuin 1 in insulin resistance and metabolic syndrome: potential biochemical mechanisms. Diabetes 2010, 59(4):1006-1015.
    • (2010) Diabetes , vol.59 , Issue.4 , pp. 1006-1015
    • de Kreutzenberg, S.V.1    Ceolotto, G.2    Papparella, I.3    Bortoluzzi, A.4    Semplicini, A.5    Dalla Man, C.6
  • 34
    • 78149285838 scopus 로고    scopus 로고
    • SIRT1/eNOS axis as a potential target against vascular senescence, dysfunction and atherosclerosis
    • Ota H., Eto M., Ogawa S., Iijima K., Akishita M., Ouchi Y. SIRT1/eNOS axis as a potential target against vascular senescence, dysfunction and atherosclerosis. Arterioscler Thromb Vasc Biol 2010, 30:2205-2211.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 2205-2211
    • Ota, H.1    Eto, M.2    Ogawa, S.3    Iijima, K.4    Akishita, M.5    Ouchi, Y.6
  • 35
    • 36749087548 scopus 로고    scopus 로고
    • Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
    • Milne J.C., Lambert P.D., Schenk S., Carney D.P., Smith J.J., Gagne D.J., et al. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature 2007, 450(7170):712-716.
    • (2007) Nature , vol.450 , Issue.7170 , pp. 712-716
    • Milne, J.C.1    Lambert, P.D.2    Schenk, S.3    Carney, D.P.4    Smith, J.J.5    Gagne, D.J.6
  • 37
    • 0032518255 scopus 로고    scopus 로고
    • Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily
    • Anderson M.J., Viars C.S., Czekay S., Cavenee W.K., Arden K.C. Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily. Genomics 1998, 47:187-199.
    • (1998) Genomics , vol.47 , pp. 187-199
    • Anderson, M.J.1    Viars, C.S.2    Czekay, S.3    Cavenee, W.K.4    Arden, K.C.5
  • 38
    • 0027959091 scopus 로고
    • Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family
    • Parry P., Wei Y., Evans G. Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family. Genes Chromosomes Cancer 1994, 11:79-84.
    • (1994) Genes Chromosomes Cancer , vol.11 , pp. 79-84
    • Parry, P.1    Wei, Y.2    Evans, G.3
  • 39
  • 40
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
    • Brunet A., Bonni A., Zigmond M.J., Lin M.Z., Juo P., Hu L.S., et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell. 1999, 96:857-868.
    • (1999) Cell. , vol.96 , pp. 857-868
    • Brunet, A.1    Bonni, A.2    Zigmond, M.J.3    Lin, M.Z.4    Juo, P.5    Hu, L.S.6
  • 41
    • 4143050290 scopus 로고    scopus 로고
    • The interaction between FOXO and SIRT1: tipping the balance towards survival
    • Giannakou M.E., Partridge L. The interaction between FOXO and SIRT1: tipping the balance towards survival. Trends Cell Biol 2004, 14:408-412.
    • (2004) Trends Cell Biol , vol.14 , pp. 408-412
    • Giannakou, M.E.1    Partridge, L.2
  • 42
    • 0037192473 scopus 로고    scopus 로고
    • Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway
    • Nemoto S., Finkel T. Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway. Science 2002, 295:2450-2452.
    • (2002) Science , vol.295 , pp. 2450-2452
    • Nemoto, S.1    Finkel, T.2
  • 43
    • 0034459180 scopus 로고    scopus 로고
    • Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1)
    • Dijkers P.F. Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1). Mol Cell Biol 2000, 20:9138-9148.
    • (2000) Mol Cell Biol , vol.20 , pp. 9138-9148
    • Dijkers, P.F.1
  • 44
    • 0037136563 scopus 로고    scopus 로고
    • Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
    • Kops G.J., Dansen T.B., Polderman P.E., Saarloos I., Wirtz K.W., Coffer P.J., et al. Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature 2002, 419:316-321.
    • (2002) Nature , vol.419 , pp. 316-321
    • Kops, G.J.1    Dansen, T.B.2    Polderman, P.E.3    Saarloos, I.4    Wirtz, K.W.5    Coffer, P.J.6
  • 45
    • 0242695672 scopus 로고    scopus 로고
    • Resveratrol: from grapevines to mammalian biology
    • Pervaiz S. Resveratrol: from grapevines to mammalian biology. FASEB J 2003, 17(14):1975-1985.
    • (2003) FASEB J , vol.17 , Issue.14 , pp. 1975-1985
    • Pervaiz, S.1
  • 46
    • 33751072349 scopus 로고    scopus 로고
    • Resveratrol improves health and survival of mice on a high-calorie diet
    • Baur J.A., Pearson K.J., Price N.L., Jamieson H.A., Lerin C., Kalra A., et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 2006, 444:337-342.
    • (2006) Nature , vol.444 , pp. 337-342
    • Baur, J.A.1    Pearson, K.J.2    Price, N.L.3    Jamieson, H.A.4    Lerin, C.5    Kalra, A.6
  • 47
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: the in vivo evidence
    • Baur J.A., Sinclair D.A. Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 2006, 5:493-506.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 48
    • 31144447091 scopus 로고    scopus 로고
    • Resveratrol, a polyphenolic phytoalexin, attenuates diabetic nephropathy in rats
    • Sharma S., Anjaneyulu M., Kulkarni S.K., Chopra K. Resveratrol, a polyphenolic phytoalexin, attenuates diabetic nephropathy in rats. Pharmacology 2006, 76:69-75.
    • (2006) Pharmacology , vol.76 , pp. 69-75
    • Sharma, S.1    Anjaneyulu, M.2    Kulkarni, S.K.3    Chopra, K.4
  • 49
    • 33744946526 scopus 로고    scopus 로고
    • Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats
    • Su H.C., Hung L.M., Chen J.K. Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats. Am J Physiol Endocrinol Metab 2006, 290:E1339-E1346.
    • (2006) Am J Physiol Endocrinol Metab , vol.290
    • Su, H.C.1    Hung, L.M.2    Chen, J.K.3
  • 50
    • 34547101726 scopus 로고    scopus 로고
    • Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of nitric oxide, thioredoxin, and heme oxygenase
    • Thirunavukkarasu M., Penumathsa S.V., Koneru S., Juhasz B., Zhan L., Otani H., et al. Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of nitric oxide, thioredoxin, and heme oxygenase. Free Radic Biol Med 2007, 43:720-729.
    • (2007) Free Radic Biol Med , vol.43 , pp. 720-729
    • Thirunavukkarasu, M.1    Penumathsa, S.V.2    Koneru, S.3    Juhasz, B.4    Zhan, L.5    Otani, H.6
  • 51
    • 33749349202 scopus 로고    scopus 로고
    • Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice
    • Zang M., Xu S., Maitland-Toolan K.A., Zuccollo A., Hou X., Jiang B., et al. Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice. Diabetes 2006, 55:2180-2191.
    • (2006) Diabetes , vol.55 , pp. 2180-2191
    • Zang, M.1    Xu, S.2    Maitland-Toolan, K.A.3    Zuccollo, A.4    Hou, X.5    Jiang, B.6
  • 52
    • 39049157857 scopus 로고    scopus 로고
    • Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state
    • Devaraj S., Dasu M.R., Rockwood J., Winter W., Griffen S.C., Jialal I. Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state. J Clin Endocrinol Metab 2008, 93(2):578-583.
    • (2008) J Clin Endocrinol Metab , vol.93 , Issue.2 , pp. 578-583
    • Devaraj, S.1    Dasu, M.R.2    Rockwood, J.3    Winter, W.4    Griffen, S.C.5    Jialal, I.6
  • 53
    • 34547119919 scopus 로고    scopus 로고
    • High glucose induces IL-1β expression in human monocytes: mechanistic insights
    • Dasu M.R., Devaraj S., Jialal I. High glucose induces IL-1β expression in human monocytes: mechanistic insights. Am J Physiol Endocrinol Metab 2007, 293:E337-E346.
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • Dasu, M.R.1    Devaraj, S.2    Jialal, I.3
  • 54
    • 33947188132 scopus 로고    scopus 로고
    • The biological effects of CRP are not attributable to endotoxin contamination: evidence from TLR4 knockdown human aortic endothelial cells
    • Dasu M.R., Devaraj S., Du Clos T.W., Jialal I. The biological effects of CRP are not attributable to endotoxin contamination: evidence from TLR4 knockdown human aortic endothelial cells. J Lipid Res 2007, 48:509-512.
    • (2007) J Lipid Res , vol.48 , pp. 509-512
    • Dasu, M.R.1    Devaraj, S.2    Du Clos, T.W.3    Jialal, I.4
  • 56
    • 0034455878 scopus 로고    scopus 로고
    • Glucose challenge stimulates reactive oxygen species (ROS) generation by leucocytes
    • Mohanty P., Hamouda W., Garg R., Aljada A., Ghanim H., Dandona P. Glucose challenge stimulates reactive oxygen species (ROS) generation by leucocytes. J Clin Endocrinol Metab 2000, 85(8):2970-2973.
    • (2000) J Clin Endocrinol Metab , vol.85 , Issue.8 , pp. 2970-2973
    • Mohanty, P.1    Hamouda, W.2    Garg, R.3    Aljada, A.4    Ghanim, H.5    Dandona, P.6
  • 57
    • 10844236451 scopus 로고    scopus 로고
    • Nutrient availability regulates SIRT1 through a forkhead-dependent pathway
    • Nemoto S., Fergusson M.M., Finkel T. Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science 2004, 306:2105-2108.
    • (2004) Science , vol.306 , pp. 2105-2108
    • Nemoto, S.1    Fergusson, M.M.2    Finkel, T.3
  • 58
    • 68049134459 scopus 로고    scopus 로고
    • Metabolic benefits from Sirt1 and Sirt1 activators
    • Chaudhary N., Pfluger P.T. Metabolic benefits from Sirt1 and Sirt1 activators. Curr Opin Clin Nutr Metab Care 2009, 12(4):431-437.
    • (2009) Curr Opin Clin Nutr Metab Care , vol.12 , Issue.4 , pp. 431-437
    • Chaudhary, N.1    Pfluger, P.T.2
  • 59
    • 33845868198 scopus 로고    scopus 로고
    • Sirtuins as potential targets for metabolic syndrome
    • Guarente L. sirtuins as potential targets for metabolic syndrome. Nature 2006, 444:868-874.
    • (2006) Nature , vol.444 , pp. 868-874
    • Guarente, L.1
  • 60
    • 47249108032 scopus 로고    scopus 로고
    • Sirtuins: novel targets for metabolic disease in drug development
    • Jiang W.J. Sirtuins: novel targets for metabolic disease in drug development. Biochem Biophys Res Commun 2008, 373:341-344.
    • (2008) Biochem Biophys Res Commun , vol.373 , pp. 341-344
    • Jiang, W.J.1
  • 61
    • 2942726155 scopus 로고    scopus 로고
    • The ins and outs of FoxO shuttling: mechanisms of FoxO transcription and transcriptional regulations
    • Van Der Heide L.P., Hoekman M.F., Smidt M.P. The ins and outs of FoxO shuttling: mechanisms of FoxO transcription and transcriptional regulations. Biochem. J. 2004, 380:297-309.
    • (2004) Biochem. J. , vol.380 , pp. 297-309
    • Van Der Heide, L.P.1    Hoekman, M.F.2    Smidt, M.P.3
  • 62
  • 63
    • 18044381312 scopus 로고    scopus 로고
    • FoxO proteins in insulin action and metabolism
    • Barthel A. FoxO proteins in insulin action and metabolism. Trends Endocrinol Metab 2005, 16:183-189.
    • (2005) Trends Endocrinol Metab , vol.16 , pp. 183-189
    • Barthel, A.1
  • 64
    • 34247600642 scopus 로고    scopus 로고
    • Resveratrol stimulates glucose transport in C2C12 myotubes by activating AMP-activated protein kinase
    • Park C.E., Kim M.J., Lee J.H., Min B.I., Bae H., Choe W., et al. Resveratrol stimulates glucose transport in C2C12 myotubes by activating AMP-activated protein kinase. Exp Mol Med 2007, 39(2):222-229.
    • (2007) Exp Mol Med , vol.39 , Issue.2 , pp. 222-229
    • Park, C.E.1    Kim, M.J.2    Lee, J.H.3    Min, B.I.4    Bae, H.5    Choe, W.6
  • 65
    • 48349144852 scopus 로고    scopus 로고
    • Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
    • Pearson K.J., Baur J.A., Lewis K.N., Peshkin L., Price N.L., Labinskyy N., et al. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab 2008, 8:157-168.
    • (2008) Cell Metab , vol.8 , pp. 157-168
    • Pearson, K.J.1    Baur, J.A.2    Lewis, K.N.3    Peshkin, L.4    Price, N.L.5    Labinskyy, N.6
  • 66
    • 52649144195 scopus 로고    scopus 로고
    • Resveratrol and novel potent activators of SIRT1: effects on aging and age-related diseases
    • Knutson M.D., Leeuwenburgh C. Resveratrol and novel potent activators of SIRT1: effects on aging and age-related diseases. Nutr Rev 2008, 66(10):591-596.
    • (2008) Nutr Rev , vol.66 , Issue.10 , pp. 591-596
    • Knutson, M.D.1    Leeuwenburgh, C.2
  • 67
    • 50649112638 scopus 로고    scopus 로고
    • SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase
    • Hou X., Xu S., Maitland-Toolan K.A., Sato K., Jiang B., Ido Y., et al. SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase. J Biol Chem 2008, 283(29):20015-20026.
    • (2008) J Biol Chem , vol.283 , Issue.29 , pp. 20015-20026
    • Hou, X.1    Xu, S.2    Maitland-Toolan, K.A.3    Sato, K.4    Jiang, B.5    Ido, Y.6
  • 68
    • 34147182364 scopus 로고    scopus 로고
    • Resveratrol attenuates oxLDL-stimulated NADPH oxidase activity and protects endothelial cells from oxidative functional damages
    • Chow S.E., Hshu Y.C., Wang J.S., Chen J.K. Resveratrol attenuates oxLDL-stimulated NADPH oxidase activity and protects endothelial cells from oxidative functional damages. J Appl Physiol 2007, 102(4):1520-1527.
    • (2007) J Appl Physiol , vol.102 , Issue.4 , pp. 1520-1527
    • Chow, S.E.1    Hshu, Y.C.2    Wang, J.S.3    Chen, J.K.4
  • 69
    • 65949114049 scopus 로고    scopus 로고
    • Resveratrol inhibits foam cell formation via NADPH oxidase 1-mediated reactive oxygen species and monocyte chemotactic protein
    • Park D.W., Baek K., Kim J.R., Lee J.J., Ryu S.H., Chin B.R., et al. Resveratrol inhibits foam cell formation via NADPH oxidase 1-mediated reactive oxygen species and monocyte chemotactic protein. Exp Mol Med 2009, 41(3):171-179.
    • (2009) Exp Mol Med , vol.41 , Issue.3 , pp. 171-179
    • Park, D.W.1    Baek, K.2    Kim, J.R.3    Lee, J.J.4    Ryu, S.H.5    Chin, B.R.6
  • 72
    • 77956585215 scopus 로고    scopus 로고
    • An antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol
    • Ghanim H., Sia C.L., Abuaysheh S., Korzeniewski K., Patnaik P., Marumganti A., et al. An antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol. J Clin Endocrinol Metab 2010, 95(9):E1-E8.
    • (2010) J Clin Endocrinol Metab , vol.95 , Issue.9
    • Ghanim, H.1    Sia, C.L.2    Abuaysheh, S.3    Korzeniewski, K.4    Patnaik, P.5    Marumganti, A.6


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