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Volumn 8, Issue 6, 2012, Pages 307-318

Nanotechnology - Novel therapeutics for CNS disorders

Author keywords

[No Author keywords available]

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; ACETYLCHOLINE; ANTISENSE OLIGONUCLEOTIDE; ARGINYLALANYLASPARAGINYLASPARTIC ACID; ARGINYLGLYCYLASPARTIC ACID; CARBON NANOTUBE; CENTRAL NERVOUS SYSTEM AGENTS; CILIARY NEUROTROPHIC FACTOR; CLIOQUINOL; CURCUMIN; DOXORUBICIN; FULLERENE DERIVATIVE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; IRINOTECAN; ISOLEUCYLLYSYLVALYLALANYLVALINE; LIPOSOME; MACROGOL; METHOTREXATE; MOLECULAR SCAFFOLD; NANOCARRIER; NERVE GROWTH FACTOR; NEUROTROPHIN 3; PACLITAXEL; RIVASTIGMINE; TRANSFERRIN; TRANSFERRIN RECEPTOR ANTIBODY; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

EID: 84862285940     PISSN: 17594758     EISSN: 17594766     Source Type: Journal    
DOI: 10.1038/nrneurol.2012.76     Document Type: Review
Times cited : (171)

References (126)
  • 1
    • 2942623871 scopus 로고    scopus 로고
    • Evidence for bulk flow of brain interstitial fluid: Significance for physiology and pathology
    • Abbott, N. J. Evidence for bulk flow of brain interstitial fluid: significance for physiology and pathology. Neurochem. Int. 45, 545-552 (2004
    • (2004) Neurochem. Int. , vol.45 , pp. 545-552
    • Abbott, N.J.1
  • 2
    • 24344446871 scopus 로고    scopus 로고
    • Clinical practice diagnosis and initial management of Parkinson's disease
    • Nutt, J. G. & Wooten, G. F. Clinical practice. Diagnosis and initial management of Parkinson's disease. N. Engl. J. Med. 353, 1021-1027 (2005
    • (2005) N. Engl. J. Med. , vol.353 , pp. 1021-1027
    • Nutt, J.G.1    Wooten, G.F.2
  • 4
    • 13944276825 scopus 로고    scopus 로고
    • Twenty years of the Alzheimer's disease amyloid hypo thesis: A genetic perspective
    • Tanzi, R. E. & Bertram, L. Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Cell 120, 545-555 (2005
    • (2005) Cell , vol.120 , pp. 545-555
    • Tanzi, R.E.1    Bertram, L.2
  • 5
    • 22344438508 scopus 로고    scopus 로고
    • Tau suppression in a neurodegenerative mouse model improves memory function
    • Santacruz, K. et al. Tau suppression in a neurodegenerative mouse model improves memory function. Science 309, 476-481 (2005
    • (2005) Science , vol.309 , pp. 476-481
    • Santacruz, K.1
  • 6
    • 0029982815 scopus 로고    scopus 로고
    • Oxidative damage in Alzheimer's
    • Smith, M. A. et al. Oxidative damage in Alzheimer's. Nature 382, 120-121 (1996
    • (1996) Nature , vol.382 , pp. 120-121
    • Smith, M.A.1
  • 8
    • 2542511697 scopus 로고    scopus 로고
    • Cholinergic nucleus basalis tauopathy emerges early in the aging-MCI-AD continuum
    • Mesulam, M., Shaw, P., Mash, D. & Weintraub, S. Cholinergic nucleus basalis tauopathy emerges early in the aging-MCI-AD continuum. Ann. Neurol. 55, 815-828 (2004
    • (2004) Ann. Neurol. , vol.55 , pp. 815-828
    • Mesulam, M.1    Shaw, P.2    Mash, D.3    Weintraub, S.4
  • 9
    • 80053212172 scopus 로고    scopus 로고
    • Nanotechnologies for Alzheimer's disease: Diagnosis, therapy, and safety issues
    • Brambilla, D. et al. Nanotechnologies for Alzheimer's disease: diagnosis, therapy, and safety issues. Nanomedicine 7, 521-540 (2011
    • (2011) Nanomedicine , vol.7 , pp. 521-540
    • Brambilla, D.1
  • 10
    • 0030457933 scopus 로고    scopus 로고
    • Three-dimensional structures of the amyloid β peptide (25-35) in membrane-mimicking environment
    • Kohno, T., Kobayashi, K., Maeda, T., Sato, K. & Takashima, A. Three-dimensional structures of the amyloid β peptide (25-35) in membrane-mimicking environment. Biochemistry 35, 16094-16104 (1996
    • (1996) Biochemistry , vol.35 , pp. 16094-16104
    • Kohno, T.1    Kobayashi, K.2    Maeda, T.3    Sato, K.4    Takashima, A.5
  • 11
    • 33750052628 scopus 로고    scopus 로고
    • PEGylated phospholipid nanomicelles interact with β-amyloid(1- 42) and mitigate its β-Sheet formation, aggregation and neurotoxicity in vitro
    • Pai, A. S., Rubinstein, I. & Onyuksel, H. PEGylated phospholipid nanomicelles interact with β-amyloid(1-42) and mitigate its β-sheet formation, aggregation and neurotoxicity in vitro. Peptides 27, 2858-2866 (2006
    • (2006) Peptides , vol.27 , pp. 2858-2866
    • Pai, A.S.1    Rubinstein, I.2    Onyuksel, H.3
  • 12
    • 20044370990 scopus 로고    scopus 로고
    • Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo
    • Yang, F. et al. Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo. J. Biol. Chem. 280, 5892-5901 (2005
    • (2005) J. Biol. Chem. , vol.280 , pp. 5892-5901
    • Yang, F.1
  • 13
    • 80053216654 scopus 로고    scopus 로고
    • Effect of curcumin-Associated and lipid ligand-Functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide
    • Taylor, M. et al. Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide. Nanomedicine 7, 541-550 (2011
    • (2011) Nanomedicine , vol.7 , pp. 541-550
    • Taylor, M.1
  • 14
    • 78650300340 scopus 로고    scopus 로고
    • Curcumin-Decorated nanoliposomes with very high affinity for amyloid-β1-42 peptide
    • Mourtas, S. et al. Curcumin-decorated nanoliposomes with very high affinity for amyloid-β1-42 peptide. Biomaterials 32, 1635-1645 (2011
    • (2011) Biomaterials , vol.32 , pp. 1635-1645
    • Mourtas, S.1
  • 16
    • 0034964390 scopus 로고    scopus 로고
    • Treatment with a copper-Zinc chelator markedly and rapidly inhibits β-amyloid accumulation in Alzheimer's disease transgenic mice
    • Cherny, R. A. et al. Treatment with a copper-zinc chelator markedly and rapidly inhibits β-amyloid accumulation in Alzheimer's disease transgenic mice. Neuron 30, 665-676 (2001
    • (2001) Neuron , vol.30 , pp. 665-676
    • Cherny, R.A.1
  • 17
    • 10744224267 scopus 로고    scopus 로고
    • Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Aβ amyloid deposition and toxicity in Alzheimer disease: A pilot phase 2 clinical trial
    • Ritchie, C. W. et al. Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Aβ amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial. Arch. Neurol. 60, 1685-1691 (2003
    • (2003) Arch. Neurol. , vol.60 , pp. 1685-1691
    • Ritchie, C.W.1
  • 18
    • 12344251715 scopus 로고    scopus 로고
    • Novel d-Penicillamine carrying nanoparticles for metal chelation therapy in Alzheimer's and other CNS diseases
    • Cui, Z. et al. Novel d-penicillamine carrying nanoparticles for metal chelation therapy in Alzheimer's and other CNS diseases. Eur. J. Pharm. Biopharm. 59, 263-272 (2005
    • (2005) Eur. J. Pharm. Biopharm. , vol.59 , pp. 263-272
    • Cui, Z.1
  • 19
    • 0142169397 scopus 로고    scopus 로고
    • Protein refolding assisted by self-Assembled nanogels as novel artificial molecular chaperone
    • Nomura, Y., Ikeda, M., Yamaguchi, N., Aoyama, Y. & Akiyoshi, K. Protein refolding assisted by self-assembled nanogels as novel artificial molecular chaperone. FEBS Lett. 553, 271-276 (2003
    • (2003) FEBS Lett. , vol.553 , pp. 271-276
    • Nomura, Y.1    Ikeda, M.2    Yamaguchi, N.3    Aoyama, Y.4    Akiyoshi, K.5
  • 20
    • 37849186419 scopus 로고    scopus 로고
    • Inhibition of the formation of amyloid β-protein fibrils using biocompatible nanogels as artificial chaperones
    • Ikeda, K., Okada, T., Sawada, S., Akiyoshi, K. & Matsuzaki, K. Inhibition of the formation of amyloid β-protein fibrils using biocompatible nanogels as artificial chaperones. FEBS Lett. 580, 6587-6595 (2006
    • (2006) FEBS Lett. , vol.580 , pp. 6587-6595
    • Ikeda, K.1    Okada, T.2    Sawada, S.3    Akiyoshi, K.4    Matsuzaki, K.5
  • 21
    • 68749092581 scopus 로고    scopus 로고
    • The binding of pullulan modified cholesteryl nanogels to Aβ oligomers and their suppression of cytotoxicity
    • Boridy, S., Takahashi, H., Akiyoshi, K. & Maysinger, D. The binding of pullulan modified cholesteryl nanogels to Aβ oligomers and their suppression of cytotoxicity. Biomaterials 30, 5583-5591 (2009
    • (2009) Biomaterials , vol.30 , pp. 5583-5591
    • Boridy, S.1    Takahashi, H.2    Akiyoshi, K.3    Maysinger, D.4
  • 22
    • 0034923434 scopus 로고    scopus 로고
    • Oxidative damage is the earliest event in Alzheimer disease
    • Nunomura, A. et al. Oxidative damage is the earliest event in Alzheimer disease. J. Neuropathol. Exp. Neurol. 60, 759-767 (2001
    • (2001) J. Neuropathol. Exp. Neurol. , vol.60 , pp. 759-767
    • Nunomura, A.1
  • 24
    • 0030130429 scopus 로고    scopus 로고
    • Buckminsterfullerenol free radical scavengers reduce excitotoxic and apoptotic death of cultured cortical neurons
    • Dugan, L. L., Gabrielsen, J. K., Yu, S. P., Lin, T. S. & Choi, D. W. Buckminsterfullerenol free radical scavengers reduce excitotoxic and apoptotic death of cultured cortical neurons. Neurobiol. Dis. 3, 129-135 (1996
    • (1996) Neurobiol. Dis. , vol.3 , pp. 129-135
    • Dugan, L.L.1    Gabrielsen, J.K.2    Yu, S.P.3    Lin, T.S.4    Choi, D.W.5
  • 25
    • 0001897915 scopus 로고    scopus 로고
    • Carboxyfullerenes as neuroprotective agents
    • Dugan, L. L. et al. Carboxyfullerenes as neuroprotective agents. Proc. Natl Acad. Sci. USA 94, 9434-9439 (1997
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 9434-9439
    • Dugan, L.L.1
  • 26
    • 34447517643 scopus 로고    scopus 로고
    • Effects of hydrated forms of C60 fullerene on amyloid 1-peptide fibrillization in vitro and performance of the cognitive task
    • Podolski, I. Y. et al. Effects of hydrated forms of C60 fullerene on amyloid 1-peptide fibrillization in vitro and performance of the cognitive task. J. Nanosci. Nanotechnol. 7, 1479-1485 (2007
    • (2007) J. Nanosci. Nanotechnol. , vol.7 , pp. 1479-1485
    • Podolski, I.Y.1
  • 27
    • 0037425565 scopus 로고    scopus 로고
    • Efficacy of cholinesterase inhibitors in the treatment of neuropsychiatric symptoms and functional impairment in Alzheimer disease: A meta-analysis
    • Trinh, N. H., Hoblyn, J., Mohanty, S. & Yaffe, K. Efficacy of cholinesterase inhibitors in the treatment of neuropsychiatric symptoms and functional impairment in Alzheimer disease: a meta-analysis. JAMA 289, 210-216 (2003
    • (2003) JAMA , vol.289 , pp. 210-216
    • Trinh, N.H.1    Hoblyn, J.2    Mohanty, S.3    Yaffe, K.4
  • 28
    • 77952678343 scopus 로고    scopus 로고
    • Pharmacological and toxicological target organelles and safe use of single-walled carbon nanotubes as drug carriers in treating Alzheimer disease
    • Yang, Z. et al. Pharmacological and toxicological target organelles and safe use of single-walled carbon nanotubes as drug carriers in treating Alzheimer disease. Nanomedicine 6, 427-441 (2010
    • (2010) Nanomedicine , vol.6 , pp. 427-441
    • Yang, Z.1
  • 29
    • 32044445745 scopus 로고    scopus 로고
    • The biocompatibility of carbon nanotubes
    • Smart, S. K., Cassady, A. I., Lu, G. Q. & Martin, D. J. The biocompatibility of carbon nanotubes. Carbon 44, 1034-1047 (2006
    • (2006) Carbon , vol.44 , pp. 1034-1047
    • Smart, S.K.1    Cassady, A.I.2    Lu, G.Q.3    Martin, D.J.4
  • 30
    • 33947630376 scopus 로고    scopus 로고
    • Translocation of poly(ethylene glycol-Co-Hexadecyl)cyanoacrylate nanoparticles into rat brain endothelial cells: Role of apolipoproteins in receptor-mediated endocytosis
    • Kim, H. R. et al. Translocation of poly(ethylene glycol-co-hexadecyl) cyanoacrylate nanoparticles into rat brain endothelial cells: role of apolipoproteins in receptor-mediated endocytosis. Biomacromolecules 8, 793-799 (2007
    • (2007) Biomacromolecules , vol.8 , pp. 793-799
    • Kim, H.R.1
  • 31
    • 40849097322 scopus 로고    scopus 로고
    • Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease
    • Wilson, B. et al. Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease. Brain Res. 1200, 159-168 (2008
    • (2008) Brain Res. , vol.1200 , pp. 159-168
    • Wilson, B.1
  • 32
    • 77957260011 scopus 로고    scopus 로고
    • Rivastigmine-loaded PLGA and PBCA nanoparticles: Preparation, optimization, characterization, in vitro and pharmacodynamic studies
    • Joshi, S. A., Chavhan, S. S. & Sawant, K. K. Rivastigmine-loaded PLGA and PBCA nanoparticles: preparation, optimization, characterization, in vitro and pharmacodynamic studies. Eur. J. Pharm. Biopharm. 76, 189-199 (2010
    • (2010) Eur. J. Pharm. Biopharm. , vol.76 , pp. 189-199
    • Joshi, S.A.1    Chavhan, S.S.2    Sawant, K.K.3
  • 33
    • 66949152096 scopus 로고    scopus 로고
    • Parkinson's disease
    • Lees, A. J., Hardy, J. & Revesz, T. Parkinson's disease. Lancet 373, 2055-2066 (2009
    • (2009) Lancet , vol.373 , pp. 2055-2066
    • Lees, A.J.1    Hardy, J.2    Revesz, T.3
  • 34
    • 19744378296 scopus 로고    scopus 로고
    • Levodopa and the progression of Parkinson's disease
    • Fahn, S. et al. Levodopa and the progression of Parkinson's disease. N. Engl. J. Med. 351, 2498-2508 (2004
    • (2004) N. Engl. J. Med. , vol.351 , pp. 2498-2508
    • Fahn, S.1
  • 35
    • 0036894795 scopus 로고    scopus 로고
    • A controlled trial of rasagiline in early Parkinson disease: The TEMPO Study
    • Group, P. S.
    • Group, P. S. A controlled trial of rasagiline in early Parkinson disease: the TEMPO Study. Arch. Neurol. 59, 1937-1943 (2002
    • (2002) Arch. Neurol. , vol.59 , pp. 1937-1943
  • 36
    • 80054804774 scopus 로고    scopus 로고
    • An update on gene therapy in Parkinson's disease
    • Witt, J. & Marks, W. J. Jr. An update on gene therapy in Parkinson's disease. Curr. Neurol. Neurosci. Rep. 11, 362-370 (2011
    • (2011) Curr. Neurol. Neurosci. Rep. , vol.11 , pp. 362-370
    • Witt, J.1    Marks Jr., W.J.2
  • 37
    • 0003008343 scopus 로고    scopus 로고
    • Synthetic DNA delivery systems
    • Luo, D. & Saltzman, W. M. Synthetic DNA delivery systems. Nat. Biotechnol. 18, 33-37 (2000
    • (2000) Nat. Biotechnol. , vol.18 , pp. 33-37
    • Luo, D.1    Saltzman, W.M.2
  • 39
    • 0037249449 scopus 로고    scopus 로고
    • Intravenous nonviral gene therapy causes normalization of striatal tyrosine hydroxylase and reversal of motor impairment in experimental parkinsonism
    • Zhang, Y., Calon, F., Zhu, C., Boado, R. J. & Pardridge, W. M. Intravenous nonviral gene therapy causes normalization of striatal tyrosine hydroxylase and reversal of motor impairment in experimental parkinsonism. Hum. Gene Ther. 14, 1-12 (2003
    • (2003) Hum. Gene Ther. , vol.14 , pp. 1-12
    • Zhang, Y.1    Calon, F.2    Zhu, C.3    Boado, R.J.4    Pardridge, W.M.5
  • 40
    • 75149113700 scopus 로고    scopus 로고
    • Compacted DNA nanoparticle gene transfer of GDNF to the rat striatum enhances the survival of grafted fetal dopamine neurons
    • Yurek, D. M., Flectcher, A. M., Kowalczyk, T. H., Padegimas, L. & Cooper, M. J. Compacted DNA nanoparticle gene transfer of GDNF to the rat striatum enhances the survival of grafted fetal dopamine neurons. Cell Transplant 18, 1183-1196 (2009
    • (2009) Cell Transplant , vol.18 , pp. 1183-1196
    • Yurek, D.M.1    Flectcher, A.M.2    Kowalczyk, T.H.3    Padegimas, L.4    Cooper, M.J.5
  • 41
    • 0031899172 scopus 로고    scopus 로고
    • Oxidative mechanisms in nigral cell death in Parkinson's disease
    • Jenner, P. Oxidative mechanisms in nigral cell death in Parkinson's disease. Mov. Disord. 13 (Suppl. 1), 24-34 (1998
    • (1998) Mov. Disord. , vol.13 , Issue.SUPPL1 , pp. 24-34
    • Jenner, P.1
  • 42
    • 0033557640 scopus 로고    scopus 로고
    • Distinct mechanisms underlie neurotoxin-Mediated cell death in cultured dopaminergic neurons
    • Lotharius, J., Dugan, L. L. & O'Malley, K. L. Distinct mechanisms underlie neurotoxin-mediated cell death in cultured dopaminergic neurons. J. Neurosci. 19, 1284-1293 (1999
    • (1999) J. Neurosci. , vol.19 , pp. 1284-1293
    • Lotharius, J.1    Dugan, L.L.2    O'Malley, K.L.3
  • 43
    • 0033062653 scopus 로고    scopus 로고
    • Carboxyfullerene prevents iron-Induced oxidative stress in rat brain
    • Lin, A. M. et al. Carboxyfullerene prevents iron-induced oxidative stress in rat brain. J. Neurochem. 72, 1634-1640 (1999
    • (1999) J. Neurochem. , vol.72 , pp. 1634-1640
    • Lin, A.M.1
  • 44
    • 77349095059 scopus 로고    scopus 로고
    • Stimulation of neuronal neurite outgrowth using functionalized carbon nanotubes
    • Matsumoto, K., Sato, C., Naka, Y., Whitby, R. & Shimizu, N. Stimulation of neuronal neurite outgrowth using functionalized carbon nanotubes. Nanotechnology 21, 115101 (2010
    • (2010) Nanotechnology , vol.21 , pp. 115101
    • Matsumoto, K.1    Sato, C.2    Naka, Y.3    Whitby, R.4    Shimizu, N.5
  • 45
    • 59849104708 scopus 로고    scopus 로고
    • Carbon nanotubes might improve neuronal performance by favouring electrical shortcuts
    • Cellot, G. et al. Carbon nanotubes might improve neuronal performance by favouring electrical shortcuts. Nat. Nanotechnol. 4, 126-133 (2009
    • (2009) Nat. Nanotechnol. , vol.4 , pp. 126-133
    • Cellot, G.1
  • 46
    • 34347342848 scopus 로고    scopus 로고
    • Interfacing neurons with carbon nanotubes: Electrical signal transfer and synaptic stimulation in cultured brain circuits
    • Mazzatenta, A. et al. Interfacing neurons with carbon nanotubes: electrical signal transfer and synaptic stimulation in cultured brain circuits. J. Neurosci. 27, 6931-6936 (2007
    • (2007) J. Neurosci. , vol.27 , pp. 6931-6936
    • Mazzatenta, A.1
  • 47
    • 49649127080 scopus 로고    scopus 로고
    • Carbon nanotubes as functional excipients for nanomedicines: II Drug delivery and biocompatibility issues
    • Foldvari, M. & Bagonluri, M. Carbon nanotubes as functional excipients for nanomedicines: II. Drug delivery and biocompatibility issues. Nanomedicine 4, 183-200 (2008
    • (2008) Nanomedicine , vol.4 , pp. 183-200
    • Foldvari, M.1    Bagonluri, M.2
  • 48
    • 14744304334 scopus 로고    scopus 로고
    • Cytotoxicity of carbon nanomaterials: Single-Wall nanotube, multi-Wall nanotube, and fullerene
    • Jia, G. et al. Cytotoxicity of carbon nanomaterials: single-wall nanotube, multi-wall nanotube, and fullerene. Environ. Sci. Technol. 39, 1378-1383 (2005
    • (2005) Environ. Sci. Technol. , vol.39 , pp. 1378-1383
    • Jia, G.1
  • 49
    • 25844464705 scopus 로고    scopus 로고
    • Single-walled carbon nanotube induces oxidative stress and activates nuclear transcription factor-?B in human keratinocytes
    • Manna, S. K. et al. Single-walled carbon nanotube induces oxidative stress and activates nuclear transcription factor-?B in human keratinocytes. Nano. Lett. 5, 1676-1684 (2005
    • (2005) Nano. Lett. , vol.5 , pp. 1676-1684
    • Manna, S.K.1
  • 50
    • 37249035104 scopus 로고    scopus 로고
    • Single-walled carbon nanotube interactions with HeLa cells
    • Yehia, H. N. et al. Single-walled carbon nanotube interactions with HeLa cells. J. Nanobiotechnology 5, 8 (2007
    • (2007) J. Nanobiotechnology , vol.5 , pp. 8
    • Yehia, H.N.1
  • 51
    • 33947355750 scopus 로고    scopus 로고
    • In vitro toxicity evaluation of single walled carbon nanotubes on human A549 lung cells
    • Davoren, M. et al. In vitro toxicity evaluation of single walled carbon nanotubes on human A549 lung cells. Toxicol. In Vitro 21, 438-448 (2007
    • (2007) Toxicol. In Vitro , vol.21 , pp. 438-448
    • Davoren, M.1
  • 52
    • 79959897174 scopus 로고    scopus 로고
    • Neuronal intrinsic mechanisms of axon regeneration
    • Liu, K., Tedeschi, A., Park, K. K. & He, Z. Neuronal intrinsic mechanisms of axon regeneration. Ann. Rev. Neurosci. 34, 131-152 (2011
    • (2011) Ann. Rev. Neurosci. , vol.34 , pp. 131-152
    • Liu, K.1    Tedeschi, A.2    Park, K.K.3    He, Z.4
  • 53
    • 70849085134 scopus 로고    scopus 로고
    • Central nervous system regeneration inhibitors and their intracellular substrates
    • Nash, M., Pribiag, H., Fournier, A. E. & Jacobson, C. Central nervous system regeneration inhibitors and their intracellular substrates. Mol. Neurobiol. 40, 224-235 (2009
    • (2009) Mol. Neurobiol. , vol.40 , pp. 224-235
    • Nash, M.1    Pribiag, H.2    Fournier, A.E.3    Jacobson, C.4
  • 54
    • 33845446354 scopus 로고    scopus 로고
    • Therapeutic approaches to promoting axonal regeneration in the adult mammalian spinal cord
    • Hannila, S. S., Siddiq, M. M. & Filbin, M. T. Therapeutic approaches to promoting axonal regeneration in the adult mammalian spinal cord. Int. Rev. Neurobiol. 77, 57-105 (2007
    • (2007) Int. Rev. Neurobiol. , vol.77 , pp. 57-105
    • Hannila, S.S.1    Siddiq, M.M.2    Filbin, M.T.3
  • 55
    • 0346500607 scopus 로고    scopus 로고
    • Fabrication of nano-structured porous PLLA scaffold intended for nerve tissue engineering
    • Yang, F. et al. Fabrication of nano-structured porous PLLA scaffold intended for nerve tissue engineering. Biomaterials 25, 1891-1900 (2004
    • (2004) Biomaterials , vol.25 , pp. 1891-1900
    • Yang, F.1
  • 56
    • 10044289544 scopus 로고    scopus 로고
    • Electrospinning of nano/micro scale poly(l-lactic acid) aligned fibers and their potential in neural tissue engineering
    • Yang, F., Murugan, R., Wang, S. & Ramakrishna, S. Electrospinning of nano/micro scale poly(l-lactic acid) aligned fibers and their potential in neural tissue engineering. Biomaterials 26, 2603-2610 (2005
    • (2005) Biomaterials , vol.26 , pp. 2603-2610
    • Yang, F.1    Murugan, R.2    Wang, S.3    Ramakrishna, S.4
  • 57
    • 78650452738 scopus 로고    scopus 로고
    • Four steps to optic nerve regeneration
    • Moore, D. L. & Goldberg, J. L. Four steps to optic nerve regeneration. J. Neuro-ophthalmol. 30, 347-360 (2010
    • (2010) J. Neuro-ophthalmol. , vol.30 , pp. 347-360
    • Moore, D.L.1    Goldberg, J.L.2
  • 58
    • 77955450730 scopus 로고    scopus 로고
    • Optic nerve regeneration
    • Benowitz, L. I. & Yin, Y. Optic nerve regeneration. Arch. Ophthalmol. 128, 1059-1064 (2011
    • (2011) Arch. Ophthalmol. , vol.128 , pp. 1059-1064
    • Benowitz, L.I.1    Yin, Y.2
  • 59
    • 0027416047 scopus 로고
    • Spontaneous assembly of a self-Complementary oligopeptide to form a stable macroscopic membrane
    • Zhang, S., Holmes, T., Lockshin, C. & Rich, A. Spontaneous assembly of a self-complementary oligopeptide to form a stable macroscopic membrane. Proc. Natl Acad. Sci. USA 90, 3334-3338 (1993
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 3334-3338
    • Zhang, S.1    Holmes, T.2    Lockshin, C.3    Rich, A.4
  • 60
    • 0034612266 scopus 로고    scopus 로고
    • Extensive neurite outgrowth and active synapse formation on self-Assembling peptide scaffolds
    • Holmes, T. C. et al. Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds. Proc. Natl Acad. Sci. USA 97, 6728-6733 (2000
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 6728-6733
    • Holmes, T.C.1
  • 61
    • 33645504776 scopus 로고    scopus 로고
    • Nano neuro knitting: Peptide nanofiber scaffold for brain repair and axon regeneration with functional return of vision
    • Ellis-Behnke, R. G. et al. Nano neuro knitting: peptide nanofiber scaffold for brain repair and axon regeneration with functional return of vision. Proc. Natl Acad. Sci. USA 103, 5054-5059 (2006
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 5054-5059
    • Ellis-Behnke, R.G.1
  • 62
    • 79956344169 scopus 로고    scopus 로고
    • CNS regeneration after chronic injury using a self-Assembled nanomaterial and MEMRI for real-Time in vivo monitoring
    • Liang, Y. X. et al. CNS regeneration after chronic injury using a self-assembled nanomaterial and MEMRI for real-time in vivo monitoring. Nanomedicine 7, 351-359 (2011
    • (2011) Nanomedicine , vol.7 , pp. 351-359
    • Liang, Y.X.1
  • 63
    • 0028867186 scopus 로고
    • Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture
    • Meyer-Franke, A., Kaplan, M. R., Pfrieger, F. W. & Barres, B. A. Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture. Neuron 15, 805-819 (1995
    • (1995) Neuron , vol.15 , pp. 805-819
    • Meyer-Franke, A.1    Kaplan, M.R.2    Pfrieger, F.W.3    Barres, B.A.4
  • 64
    • 26844530250 scopus 로고    scopus 로고
    • Stimulation of neurite outgrowth by neurotrophins delivered from degradable hydrogels
    • Burdick, J. A., Ward, M., Liang, E., Young, M. J. & Langer, R. Stimulation of neurite outgrowth by neurotrophins delivered from degradable hydrogels. Biomaterials 27, 452-459 (2006
    • (2006) Biomaterials , vol.27 , pp. 452-459
    • Burdick, J.A.1    Ward, M.2    Liang, E.3    Young, M.J.4    Langer, R.5
  • 65
    • 30444433522 scopus 로고    scopus 로고
    • Growth factor and cytokine regulation of chondroitin sulfate proteoglycans by astrocytes
    • Smith, G. M. & Strunz, C. Growth factor and cytokine regulation of chondroitin sulfate proteoglycans by astrocytes. Glia 52, 209-218 (2005
    • (2005) Glia , vol.52 , pp. 209-218
    • Smith, G.M.1    Strunz, C.2
  • 66
    • 33746068303 scopus 로고    scopus 로고
    • Epidermal growth factor receptor activation: An upstream signal for transition of quiescent astrocytes into reactive astrocytes after neural injury
    • Liu, B., Chen, H., Johns, T. G. & Neufeld, A. H. Epidermal growth factor receptor activation: an upstream signal for transition of quiescent astrocytes into reactive astrocytes after neural injury. J. Neurosci. 26, 7532-7540 (2006
    • (2006) J. Neurosci. , vol.26 , pp. 7532-7540
    • Liu, B.1    Chen, H.2    Johns, T.G.3    Neufeld, A.H.4
  • 67
    • 26444459836 scopus 로고    scopus 로고
    • EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans
    • Koprivica, V. et al. EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans. Science 310, 106-110 (2005
    • (2005) Science , vol.310 , pp. 106-110
    • Koprivica, V.1
  • 68
    • 79959809653 scopus 로고    scopus 로고
    • Nanospheres delivering the EGFR TKI AG1478 promote optic nerve regeneration: The role of size for intraocular drug delivery
    • Robinson, R. et al. Nanospheres delivering the EGFR TKI AG1478 promote optic nerve regeneration: the role of size for intraocular drug delivery. ACS Nano 5, 4392-4400 (2011
    • (2011) ACS Nano , vol.5 , pp. 4392-4400
    • Robinson, R.1
  • 70
    • 7244247026 scopus 로고    scopus 로고
    • A global perspective on spinal cord injury epidemiology
    • Ackery, A., Tator, C. & Krassioukov, A. A global perspective on spinal cord injury epidemiology. J. Neurotrauma 21, 1355-1370 (2004
    • (2004) J. Neurotrauma , vol.21 , pp. 1355-1370
    • Ackery, A.1    Tator, C.2    Krassioukov, A.3
  • 71
    • 0037039823 scopus 로고    scopus 로고
    • Repairing the injured spinal cord
    • Schwab, M. E. Repairing the injured spinal cord. Science 295, 1029-1031 (2002
    • (2002) Science , vol.295 , pp. 1029-1031
    • Schwab, M.E.1
  • 72
    • 77954862426 scopus 로고    scopus 로고
    • Stem cell therapies for spinal cord injury
    • Sahni, V. & Kessler, J. A. Stem cell therapies for spinal cord injury. Nat. Rev. Neurol. 6, 363-372 (2010
    • (2010) Nat. Rev. Neurol. , vol.6 , pp. 363-372
    • Sahni, V.1    Kessler, J.A.2
  • 73
    • 63849186608 scopus 로고    scopus 로고
    • Protection and repair of the injured spinal cord: A review of completed, ongoing, and planned clinical trials for acute spinal cord injury
    • Hawryluk, G. W., Rowland, J., Kwon, B. K. & Fehlings, M. G. Protection and repair of the injured spinal cord: a review of completed, ongoing, and planned clinical trials for acute spinal cord injury. Neurosurg. Focus 25, E14 (2008
    • (2008) Neurosurg. Focus , vol.25
    • Hawryluk, G.W.1    Rowland, J.2    Kwon, B.K.3    Fehlings, M.G.4
  • 74
    • 0032756237 scopus 로고    scopus 로고
    • Neural tissue formation within porous hydrogels implanted in brain and spinal cord lesions: Ultrastructural, immunohistochemical, and diffusion studies
    • Woerly, S. et al. Neural tissue formation within porous hydrogels implanted in brain and spinal cord lesions: ultrastructural, immunohistochemical, and diffusion studies. Tissue Eng. 5, 467-488 (1999
    • (1999) Tissue Eng. , vol.5 , pp. 467-488
    • Woerly, S.1
  • 75
    • 0027832390 scopus 로고
    • Integrins: A review of their structure and mechanisms of ligand binding
    • Tuckwell, D. S., Weston, S. A. & Humphries, M. J. Integrins: a review of their structure and mechanisms of ligand binding. Symp. Soc. Exp. Biol. 47, 107-136 (1993
    • (1993) Symp. Soc. Exp. Biol. , vol.47 , pp. 107-136
    • Tuckwell, D.S.1    Weston, S.A.2    Humphries, M.J.3
  • 76
    • 0035098617 scopus 로고    scopus 로고
    • Spinal cord repair with PHPMA hydrogel containing RGD peptides (NeuroGel
    • Woerly, S., Pinet, E., de Robertis, L., Van Diep, D. & Bousmina, M. Spinal cord repair with PHPMA hydrogel containing RGD peptides (NeuroGel). Biomaterials 22, 1095-1111 (2001
    • (2001) Biomaterials , vol.22 , pp. 1095-1111
    • Woerly, S.1    Pinet, E.2    De Robertis, L.3    Van Diep, D.4    Bousmina, M.5
  • 77
    • 0035576371 scopus 로고    scopus 로고
    • Axonal regeneration and functional recovery after complete spinal cord transection in rats by delayed treatment with transplants and neurotrophins
    • Coumans, J. V. et al. Axonal regeneration and functional recovery after complete spinal cord transection in rats by delayed treatment with transplants and neurotrophins. J. Neurosci. 21, 9334-9344 (2001
    • (2001) J. Neurosci. , vol.21 , pp. 9334-9344
    • Coumans, J.V.1
  • 78
    • 33748430801 scopus 로고    scopus 로고
    • An injectable, biodegradable hydrogel for trophic factor delivery enhances axonal rewiring and improves performance after spinal cord injury
    • Piantino, J., Burdick, J. A., Goldberg, D., Langer, R. & Benowitz, L. I. An injectable, biodegradable hydrogel for trophic factor delivery enhances axonal rewiring and improves performance after spinal cord injury. Exp. Neurol. 201, 359-367 (2006
    • (2006) Exp. Neurol. , vol.201 , pp. 359-367
    • Piantino, J.1    Burdick, J.A.2    Goldberg, D.3    Langer, R.4    Benowitz, L.I.5
  • 79
    • 0037022618 scopus 로고    scopus 로고
    • Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells
    • Teng, Y. D. et al. Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells. Proc. Natl Acad. Sci. USA 99, 3024-3029 (2002
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 3024-3029
    • Teng, Y.D.1
  • 80
    • 33645092895 scopus 로고    scopus 로고
    • Development of a tissue-engineered composite implant for treating traumatic paraplegia in rats
    • Rochkind, S. et al. Development of a tissue-engineered composite implant for treating traumatic paraplegia in rats. Eur. Spine J. 15, 234-245 (2006
    • (2006) Eur. Spine J. , vol.15 , pp. 234-245
    • Rochkind, S.1
  • 81
    • 36749028224 scopus 로고    scopus 로고
    • Reknitting the injured spinal cord by self-Assembling peptide nanofiber scaffold
    • Guo, J. et al. Reknitting the injured spinal cord by self-assembling peptide nanofiber scaffold. Nanomedicine 3, 311-321 (2007
    • (2007) Nanomedicine , vol.3 , pp. 311-321
    • Guo, J.1
  • 82
    • 15944402003 scopus 로고    scopus 로고
    • Nanotechnology approaches for the regeneration and neuroprotection of the central nervous system
    • Silva, G. A. Nanotechnology approaches for the regeneration and neuroprotection of the central nervous system. Surg. Neurol. 63, 301-306 (2005
    • (2005) Surg. Neurol. , vol.63 , pp. 301-306
    • Silva, G.A.1
  • 83
    • 0035941074 scopus 로고    scopus 로고
    • Self-Assembly and mineralization of peptide-Amphiphile nanofibers
    • Hartgerink, J. D., Beniash, E. & Stupp, S. I. Self-assembly and mineralization of peptide-amphiphile nanofibers. Science 294, 1684-1688 (2001
    • (2001) Science , vol.294 , pp. 1684-1688
    • Hartgerink, J.D.1    Beniash, E.2    Stupp, S.I.3
  • 84
    • 0037117498 scopus 로고    scopus 로고
    • Peptide-amphiphile nanofibers: A versatile scaffold for the preparation of self-assembling materials
    • Hartgerink, J. D., Beniash, E. & Stupp, S. I. Peptide-amphiphile nanofibers: a versatile scaffold for the preparation of self-assembling materials. Proc. Natl Acad. Sci. USA 99, 5133-5138 (2002
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 5133-5138
    • Hartgerink, J.D.1    Beniash, E.2    Stupp, S.I.3
  • 85
    • 0024443667 scopus 로고
    • A synthetic peptide containing the IKVAV sequence from the A chain of laminin mediates cell attachment, migration, and neurite outgrowth
    • Tashiro, K. et al. A synthetic peptide containing the IKVAV sequence from the A chain of laminin mediates cell attachment, migration, and neurite outgrowth. J. Biol. Chem. 264, 16174-16182 (1989
    • (1989) J. Biol. Chem. , vol.264 , pp. 16174-16182
    • Tashiro, K.1
  • 86
    • 0025853668 scopus 로고
    • Fetal rat septal cells adhere to and extend processes on basement membrane, laminin, and a synthetic peptide from the laminin A chain sequence
    • Jucker, M., Kleinman, H. K. & Ingram, D. K. Fetal rat septal cells adhere to and extend processes on basement membrane, laminin, and a synthetic peptide from the laminin A chain sequence. J. Neurosci. Res. 28, 507-517 (1991
    • (1991) J. Neurosci. Res. , vol.28 , pp. 507-517
    • Jucker, M.1    Kleinman, H.K.2    Ingram, D.K.3
  • 87
    • 1442281238 scopus 로고    scopus 로고
    • Selective differentiation of neural progenitor cells by high-Epitope density nanofibers
    • Silva, G. A. et al. Selective differentiation of neural progenitor cells by high-epitope density nanofibers. Science 303, 1352-1355 (2004
    • (2004) Science , vol.303 , pp. 1352-1355
    • Silva, G.A.1
  • 88
    • 43649108455 scopus 로고    scopus 로고
    • Self-Assembling nanofibers inhibit glial scar formation and promote axon elongation after spinal cord injury
    • Tysseling-Mattiace V. M. et al.
    • Tysseling-Mattiace, V. M. et al. Self-assembling nanofibers inhibit glial scar formation and promote axon elongation after spinal cord injury. J. Neurosci. 28, 3814-3823 (2008
    • (2008) J. Neurosci. , Issue.28 , pp. 3814-3823
  • 89
    • 78149312776 scopus 로고    scopus 로고
    • Self-Assembling peptide amphiphile promotes plasticity of serotonergic fibers following spinal cord injury
    • Tysseling, V. M. et al. Self-assembling peptide amphiphile promotes plasticity of serotonergic fibers following spinal cord injury. J. Neurosci. Res. 88, 3161-3170 (2010
    • (2010) J. Neurosci. Res. , Issue.88 , pp. 3161-3170
    • Tysseling, V.M.1
  • 91
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp, R. et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 352, 987-996 (2005
    • (2005) N. Engl. J. Med. , vol.352 , pp. 987-996
    • Stupp, R.1
  • 93
    • 33747168829 scopus 로고    scopus 로고
    • New trends in the medical management of glioblastoma multiforme: The role of temozolomide chemotherapy
    • Dehdashti, A. R., Hegi, M. E., Regli, L., Pica, A. & Stupp, R. New trends in the medical management of glioblastoma multiforme: the role of temozolomide chemotherapy. Neurosurg. Focus 20, E6 (2006
    • (2006) Neurosurg. Focus , vol.20
    • Dehdashti, A.R.1    Hegi, M.E.2    Regli, L.3    Pica, A.4    Stupp, R.5
  • 94
    • 79961190845 scopus 로고    scopus 로고
    • The sequential use of carmustine wafers (Gliadel®) and post-operative radiotherapy with concomitant temozolomide followed by adjuvant temozolomide: A clinical review
    • Dixit, S., Hingorani, M., Achawal, S. & Scott, I. The sequential use of carmustine wafers (Gliadel®) and post-operative radiotherapy with concomitant temozolomide followed by adjuvant temozolomide: a clinical review. Br. J. Neurosurg. 25, 459-469 (2011
    • (2011) Br. J. Neurosurg. , vol.25 , pp. 459-469
    • Dixit, S.1    Hingorani, M.2    Achawal, S.3    Scott, I.4
  • 95
    • 1842500007 scopus 로고    scopus 로고
    • Phase II trial of gefitinib in recurrent glioblastoma
    • Rich, J. N. et al. Phase II trial of gefitinib in recurrent glioblastoma. J. Clin. Oncol. 22, 133-142 (2004
    • (2004) J. Clin. Oncol. , vol.22 , pp. 133-142
    • Rich, J.N.1
  • 96
    • 33344460518 scopus 로고    scopus 로고
    • Influence of particle size on transport of methotrexate across blood brain barrier by polysorbate 80-coated polybutylcyanoacrylate nanoparticles
    • Gao, K. & Jiang, X. Influence of particle size on transport of methotrexate across blood brain barrier by polysorbate 80-coated polybutylcyanoacrylate nanoparticles. Int. J. Pharm. 310, 213-219 (2006
    • (2006) Int. J. Pharm. , vol.310 , pp. 213-219
    • Gao, K.1    Jiang, X.2
  • 97
    • 79960297652 scopus 로고    scopus 로고
    • Enhanced brain targeting of temozolomide in polysorbate-80 coated polybutylcyanoacrylate nanoparticles
    • Tian, X. H. et al. Enhanced brain targeting of temozolomide in polysorbate-80 coated polybutylcyanoacrylate nanoparticles. Int. J. Nanomedicine 6, 445-452 (2011
    • (2011) Int. J. Nanomedicine , vol.6 , pp. 445-452
    • Tian, X.H.1
  • 98
    • 41349095417 scopus 로고    scopus 로고
    • Solid lipid nanoparticles of temozolomide: Potential reduction of cardial and nephric toxicity
    • Huang, G., Zhang, N., Bi, X. & Dou, M. Solid lipid nanoparticles of temozolomide: potential reduction of cardial and nephric toxicity. Int. J. Pharm. 355, 314-320 (2008
    • (2008) Int. J. Pharm. , vol.355 , pp. 314-320
    • Huang, G.1    Zhang, N.2    Bi, X.3    Dou, M.4
  • 99
    • 33646124502 scopus 로고    scopus 로고
    • Etoposide nanocarriers suppress glioma cell growth by intracellular drug delivery and simultaneous P-Glycoprotein inhibition
    • Lamprecht, A. & Benoit, J. P. Etoposide nanocarriers suppress glioma cell growth by intracellular drug delivery and simultaneous P-glycoprotein inhibition. J. Control Release 112, 208-213 (2006
    • (2006) J. Control Release , vol.112 , pp. 208-213
    • Lamprecht, A.1    Benoit, J.P.2
  • 100
    • 33748313404 scopus 로고    scopus 로고
    • A new generation of anticancer, drug-loaded, colloidal vectors reverses multidrug resistance in glioma and reduces tumor progression in rats
    • Garcion, E. et al. A new generation of anticancer, drug-loaded, colloidal vectors reverses multidrug resistance in glioma and reduces tumor progression in rats. Mol. Cancer Ther. 5, 1710-1722 (2006
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 1710-1722
    • Garcion, E.1
  • 101
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • Dean, M., Fojo, T. & Bates, S. Tumour stem cells and drug resistance. Nat. Rev. Cancer 5, 275-284 (2005
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 102
    • 39749200864 scopus 로고    scopus 로고
    • Methotrexate loaded polyether-copolyester dendrimers for the treatment of gliomas: Enhanced efficacy and intratumoral transport capability
    • Dhanikula, R. S., Argaw, A., Bouchard, J. F. & Hildgen, P. Methotrexate loaded polyether-copolyester dendrimers for the treatment of gliomas: enhanced efficacy and intratumoral transport capability. Mol. Pharm. 5, 105-116 (2008
    • (2008) Mol. Pharm. , vol.5 , pp. 105-116
    • Dhanikula, R.S.1    Argaw, A.2    Bouchard, J.F.3    Hildgen, P.4
  • 103
    • 78449252867 scopus 로고    scopus 로고
    • PEGylated Poly(amidoamine) dendrimer-Based dual-Targeting carrier for treating brain tumors
    • He, H. et al. PEGylated Poly(amidoamine) dendrimer-based dual-targeting carrier for treating brain tumors. Biomaterials 32, 478-487 (2010
    • (2010) Biomaterials , vol.32 , pp. 478-487
    • He, H.1
  • 104
    • 78650820848 scopus 로고    scopus 로고
    • Surface expressed nucleolin is constantly induced in tumor cells to mediate calcium-dependent ligand internalization
    • Hovanessian, A. G. et al. Surface expressed nucleolin is constantly induced in tumor cells to mediate calcium-dependent ligand internalization. PLoS ONE 5, e15787 (2010
    • (2010) PLoS ONE , vol.5
    • Hovanessian, A.G.1
  • 105
    • 61449216884 scopus 로고    scopus 로고
    • Cell surface nucleolin antagonist causes endothelial cell apoptosis and normalization of tumor vasculature
    • Fogal, V., Sugahara, K. N., Ruoslahti, E. & Christian, S. Cell surface nucleolin antagonist causes endothelial cell apoptosis and normalization of tumor vasculature. Angiogenesis 12, 91-100 (2009
    • (2009) Angiogenesis , vol.12 , pp. 91-100
    • Fogal, V.1    Sugahara, K.N.2    Ruoslahti, E.3    Christian, S.4
  • 106
    • 80051817418 scopus 로고    scopus 로고
    • Aptamer-functionalized PEG-PLGA nanoparticles for enhanced anti-Glioma drug delivery
    • Guo, J. et al. Aptamer-functionalized PEG-PLGA nanoparticles for enhanced anti-glioma drug delivery. Biomaterials 32, 8010-8020 (2011
    • (2011) Biomaterials , vol.32 , pp. 8010-8020
    • Guo, J.1
  • 107
    • 48749095941 scopus 로고    scopus 로고
    • Involvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector angiopep-2
    • Demeule, M. et al. Involvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector angiopep-2. J. Neurochem. 106, 1534-1544 (2008
    • (2008) J. Neurochem. , vol.106 , pp. 1534-1544
    • Demeule, M.1
  • 108
    • 79955104821 scopus 로고    scopus 로고
    • Angiopep-conjugated poly(ethylene glycol)-Co-Poly(e-caprolactone) nanoparticles as dual-targeting drug delivery system for brain glioma
    • Xin, H. et al. Angiopep-conjugated poly(ethylene glycol)-co-poly(e- caprolactone) nanoparticles as dual-targeting drug delivery system for brain glioma. Biomaterials 32, 4293-4305 (2011
    • (2011) Biomaterials , vol.32 , pp. 4293-4305
    • Xin, H.1
  • 109
    • 0037731636 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR-and EGFRvIII-overexpressing tumor cells
    • Mamot, C. et al. Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR-and EGFRvIII-overexpressing tumor cells. Cancer Res. 63, 3154-3161 (2003
    • (2003) Cancer Res. , vol.63 , pp. 3154-3161
    • Mamot, C.1
  • 110
    • 29244489232 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-targeted immunoliposomes significantly enhance the efficacy of multiple anticancer drugs in vivo
    • Mamot, C. et al. Epidermal growth factor receptor-targeted immunoliposomes significantly enhance the efficacy of multiple anticancer drugs in vivo. Cancer Res. 65, 11631-11638 (2005
    • (2005) Cancer Res. , vol.65 , pp. 11631-11638
    • Mamot, C.1
  • 111
    • 77955388676 scopus 로고    scopus 로고
    • EGFRvIII antibody-conjugated iron oxide nanoparticles for magnetic resonance imaging-guided convection-enhanced delivery and targeted therapy of glioblastoma
    • Hadjipanayis, C. G. et al. EGFRvIII antibody-conjugated iron oxide nanoparticles for magnetic resonance imaging-guided convection-enhanced delivery and targeted therapy of glioblastoma. Cancer Res. 70, 6303-6312 (2010
    • (2010) Cancer Res. , vol.70 , pp. 6303-6312
    • Hadjipanayis, C.G.1
  • 112
    • 33846188096 scopus 로고    scopus 로고
    • Cationic albumin-conjugated pegylated nanoparticles allow gene delivery into brain tumors via intravenous administration
    • Lu, W., Sun, Q., Wan, J., She, Z. & Jiang, X. G. Cationic albumin-conjugated pegylated nanoparticles allow gene delivery into brain tumors via intravenous administration. Cancer Res. 66, 11878-11887 (2006
    • (2006) Cancer Res. , vol.66 , pp. 11878-11887
    • Lu, W.1    Sun, Q.2    Wan, J.3    She, Z.4    Jiang, X.G.5
  • 113
    • 0036518450 scopus 로고    scopus 로고
    • Receptor-Mediated delivery of an antisense gene to human brain cancer cells
    • Zhang, Y., Jeong Lee, H., Boado, R. J. & Pardridge, W. M. Receptor-mediated delivery of an antisense gene to human brain cancer cells. J. Gene Med. 4, 183-194 (2002
    • (2002) J. Gene Med. , vol.4 , pp. 183-194
    • Zhang, Y.1    Jeong Lee, H.2    Boado, R.J.3    Pardridge, W.M.4
  • 114
    • 0036665418 scopus 로고    scopus 로고
    • Antisense gene therapy of brain cancer with an artificial virus gene delivery system
    • Zhang, Y., Zhu, C. & Pardridge, W. M. Antisense gene therapy of brain cancer with an artificial virus gene delivery system. Mol. Ther. 6, 67-72 (2002
    • (2002) Mol. Ther. , vol.6 , pp. 67-72
    • Zhang, Y.1    Zhu, C.2    Pardridge, W.M.3
  • 115
    • 78149245451 scopus 로고    scopus 로고
    • Inhibition of brain tumor growth by intravenous poly (beta-l-Malic acid) nanobioconjugate with pH-Dependent drug release [corrected]
    • Ding, H. et al. Inhibition of brain tumor growth by intravenous poly (beta-l-malic acid) nanobioconjugate with pH-dependent drug release [corrected]. Proc. Natl Acad. Sci. USA 107, 18143-18148 (2010
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 18143-18148
    • Ding, H.1
  • 116
    • 80054795004 scopus 로고    scopus 로고
    • Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma
    • Agemy, L. et al. Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma. Proc. Natl Acad. Sci. USA 108, 17450-17455 (2011
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 17450-17455
    • Agemy, L.1
  • 117
    • 84862271101 scopus 로고    scopus 로고
    • US National Library of Medicine. A phase I trial of nanoliposomal CPT-11 (NL CPT-11) in patients with recurrent high-grade gliomas
    • US National Library of Medicine. A phase I trial of nanoliposomal CPT-11 (NL CPT-11) in patients with recurrent high-grade gliomas. ClinicalTrials.gov [online], http://clinicaltrials.gov/ct2/show/NCT00734682?term= NCT00734682&rank=1 (2011
    • (2011) ClinicalTrials.gov Online
  • 118
    • 33645049055 scopus 로고    scopus 로고
    • Novel nanoliposomal CPT-11 infused by convection-Enhanced delivery in intracranial tumors: Pharmacology and efficacy
    • Noble, C. O. et al. Novel nanoliposomal CPT-11 infused by convection-enhanced delivery in intracranial tumors: pharmacology and efficacy. Cancer Res. 66, 2801-2806 (2006
    • (2006) Cancer Res. , vol.66 , pp. 2801-2806
    • Noble, C.O.1
  • 119
    • 79551574795 scopus 로고    scopus 로고
    • Toxicology of engineered nanomaterials: Focus on biocompatibility, biodistribution and biodegradation
    • Kunzmann, A. et al. Toxicology of engineered nanomaterials: focus on biocompatibility, biodistribution and biodegradation. Biochim. Biophys. Acta 1810, 361-373 (2010
    • (2010) Biochim. Biophys. Acta , vol.1810 , pp. 361-373
    • Kunzmann, A.1
  • 120
    • 33748118294 scopus 로고    scopus 로고
    • Nanomedicines and nanotoxicology: Some physiological principles
    • Garnett, M. C. & Kallinteri, P. Nanomedicines and nanotoxicology: some physiological principles. Occup. Med. (Lond.) 56, 307-311 (2006
    • (2006) Occup. Med. (Lond.) , vol.56 , pp. 307-311
    • Garnett, M.C.1    Kallinteri, P.2
  • 121
    • 67349234417 scopus 로고    scopus 로고
    • Regulatory perspective on the importance of ADME assessment of nanoscale material containing drugs
    • Zolnik, B. S. & Sadrieh, N. Regulatory perspective on the importance of ADME assessment of nanoscale material containing drugs. Adv. Drug Deliv. Rev. 61, 422-427 (2009
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , pp. 422-427
    • Zolnik, B.S.1    Sadrieh, N.2
  • 122
    • 34248663609 scopus 로고    scopus 로고
    • Nanotechnology Task Force Report 2007
    • Nanotechnology Task Force Report 2007. U.S. Food and Drug Administration [online], http://www.fda.gov/ScienceResearch/SpecialTopics/Nanotechnology/ NanotechnologyTaskForceReport2007/default.htm (2007
    • (2007) U.S. Food and Drug Administration Online
  • 123
    • 42649126357 scopus 로고    scopus 로고
    • Clinical toxicities of nanocarrier systems
    • Vega-Villa, K. R. et al. Clinical toxicities of nanocarrier systems. Adv. Drug Deliv. Rev. 60, 929-938 (2008
    • (2008) Adv. Drug Deliv. Rev. , vol.60 , pp. 929-938
    • Vega-Villa, K.R.1
  • 125
    • 67349133554 scopus 로고    scopus 로고
    • NanoGenotoxicology: The DNA damaging potential of engineered nanomaterials
    • Singh, N. et al. NanoGenotoxicology: the DNA damaging potential of engineered nanomaterials. Biomaterials 30, 3891-3914 (2009
    • (2009) Biomaterials , vol.30 , pp. 3891-3914
    • Singh, N.1
  • 126
    • 34547690726 scopus 로고    scopus 로고
    • Immunological properties of engineered nanomaterials
    • Dobrovolskaia, M. A. & McNeil, S. E. Immunological properties of engineered nanomaterials. Nat. Nanotechnol. 2, 469-478 (2007)
    • (2007) Nat. Nanotechnol. , vol.2 , pp. 469-478
    • Dobrovolskaia, M.A.1    McNeil, S.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.