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Volumn 12, Issue 1, 2009, Pages 91-100

Cell surface nucleolin antagonist causes endothelial cell apoptosis and normalization of tumor vasculature

Author keywords

Angiogenesis; Bcl 2; Homing peptides; Tumor targeting

Indexed keywords

ANTIBODY; MESSENGER RNA; NCL 3; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEOLIN; NUCLEOLIN ANTIBODY; PROTEIN BCL 2; UNCLASSIFIED DRUG;

EID: 61449216884     PISSN: 09696970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10456-009-9137-5     Document Type: Article
Times cited : (77)

References (32)
  • 1
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • 3. 10.1016/S0092-8674(00)80108-7
    • D Hanahan J Folkman 1996 Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis Cell 86 3 353 364 10.1016/S0092-8674(00) 80108-7
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 2
    • 0036488496 scopus 로고    scopus 로고
    • Specialization of tumour vasculature
    • 2. 10.1038/nrc724
    • E Ruoslahti 2002 Specialization of tumour vasculature Nat Rev Cancer 2 2 83 90 10.1038/nrc724
    • (2002) Nat Rev Cancer , vol.2 , pp. 83-90
    • Ruoslahti, E.1
  • 3
    • 0034682892 scopus 로고    scopus 로고
    • Genes expressed in human tumor endothelium
    • 5482. 10.1126/science.289.5482.1197
    • B St Croix C Rago V Velculescu 2000 Genes expressed in human tumor endothelium Science 289 5482 1197 1202 10.1126/science.289.5482.1197
    • (2000) Science , vol.289 , pp. 1197-1202
    • St Croix, B.1    Rago, C.2    Velculescu, V.3
  • 4
    • 35748970483 scopus 로고    scopus 로고
    • Tumor microvasculature and microenvironment: Targets for anti-angiogenesis and normalization
    • 2-3. 10.1016/j.mvr.2007.05.003
    • D Fukumura RK Jain 2007 Tumor microvasculature and microenvironment: targets for anti-angiogenesis and normalization Microvasc Res 74 2-3 72 84 10.1016/j.mvr.2007.05.003
    • (2007) Microvasc Res , vol.74 , pp. 72-84
    • Fukumura, D.1    Jain, R.K.2
  • 5
    • 2442621619 scopus 로고    scopus 로고
    • Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
    • 5. 10.1038/nrd1381
    • N Ferrara KJ Hillan HP Gerber 2004 Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer Nat Rev Drug Discov 3 5 391 400 10.1038/nrd1381
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 391-400
    • Ferrara, N.1    Hillan, K.J.2    Gerber, H.P.3
  • 6
    • 0344304541 scopus 로고    scopus 로고
    • Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels
    • 4. 10.1083/jcb.200304132
    • S Christian J Pilch ME Akerman 2003 Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels J Cell Biol 163 4 871 878 10.1083/jcb.200304132
    • (2003) J Cell Biol , vol.163 , pp. 871-878
    • Christian, S.1    Pilch, J.2    Akerman, M.E.3
  • 7
    • 33646391491 scopus 로고    scopus 로고
    • The angiogenic function of nucleolin is mediated by vascular endothelial growth factor and nonmuscle myosin
    • 9. 10.1182/blood-2005-07-2961
    • Y Huang H Shi H Zhou 2006 The angiogenic function of nucleolin is mediated by vascular endothelial growth factor and nonmuscle myosin Blood 107 9 3564 3571 10.1182/blood-2005-07-2961
    • (2006) Blood , vol.107 , pp. 3564-3571
    • Huang, Y.1    Shi, H.2    Zhou, H.3
  • 8
    • 49449117054 scopus 로고    scopus 로고
    • Suppression of tumor growth and angiogenesis by a specific antagonist of the cell-surface expressed nucleolin
    • 6. 10.1371/journal.pone.0002518
    • D Destouches D El Khoury Y Hamma-Kourbali 2008 Suppression of tumor growth and angiogenesis by a specific antagonist of the cell-surface expressed nucleolin PLoS ONE 3 6 e2518 10.1371/journal.pone.0002518
    • (2008) PLoS ONE , vol.3 , pp. 2518
    • Destouches, D.1    El Khoury, D.2    Hamma-Kourbali, Y.3
  • 9
    • 0032921853 scopus 로고    scopus 로고
    • Structure and functions of nucleolin
    • Pt 6
    • H Ginisty H Sicard B Roger 1999 Structure and functions of nucleolin J Cell Sci 112 Pt 6 761 772
    • (1999) J Cell Sci , vol.112 , pp. 761-772
    • Ginisty, H.1    Sicard, H.2    Roger, B.3
  • 10
    • 0032754311 scopus 로고    scopus 로고
    • Molecular dissection of nucleolin's role in growth and cell proliferation: New insights
    • 14
    • M Srivastava HB Pollard 1999 Molecular dissection of nucleolin's role in growth and cell proliferation: new insights FASEB J 13 14 1911 1922
    • (1999) FASEB J , vol.13 , pp. 1911-1922
    • Srivastava, M.1    Pollard, H.B.2
  • 11
    • 0024966024 scopus 로고
    • Major nucleolar proteins shuttle between nucleus and cytoplasm
    • 3. 10.1016/0092-8674(89)90241-9
    • RA Borer CF Lehner HM Eppenberger 1989 Major nucleolar proteins shuttle between nucleus and cytoplasm Cell 56 3 379 390 10.1016/0092-8674(89)90241-9
    • (1989) Cell , vol.56 , pp. 379-390
    • Borer, R.A.1    Lehner, C.F.2    Eppenberger, H.M.3
  • 12
    • 0032499570 scopus 로고    scopus 로고
    • Effect of laminin on the nuclear localization of nucleolin in rat intestinal epithelial IEC-6 cells
    • 1. 10.1006/bbrc.1998.8754
    • D Yu MZ Schwartz R Petryshyn 1998 Effect of laminin on the nuclear localization of nucleolin in rat intestinal epithelial IEC-6 cells Biochem Biophys Res Commun 247 1 186 192 10.1006/bbrc.1998.8754
    • (1998) Biochem Biophys Res Commun , vol.247 , pp. 186-192
    • Yu, D.1    Schwartz, M.Z.2    Petryshyn, R.3
  • 13
    • 0035893557 scopus 로고    scopus 로고
    • Identification of nucleolin as a new L-selectin ligand
    • Pt 3. 10.1042/0264-6021:3600531
    • G Harms R Kraft G Grelle 2001 Identification of nucleolin as a new L-selectin ligand Biochem J 360 Pt 3 531 538 10.1042/0264-6021:3600531
    • (2001) Biochem J , vol.360 , pp. 531-538
    • Harms, G.1    Kraft, R.2    Grelle, G.3
  • 14
    • 0037020240 scopus 로고    scopus 로고
    • The anti-HIV cytokine midkine binds the cell surface-expressed nucleolin as a low affinity receptor
    • 40. 10.1074/jbc.M201194200
    • EA Said B Krust S Nisole 2002 The anti-HIV cytokine midkine binds the cell surface-expressed nucleolin as a low affinity receptor J Biol Chem 277 40 37492 37502 10.1074/jbc.M201194200
    • (2002) J Biol Chem , vol.277 , pp. 37492-37502
    • Said, E.A.1    Krust, B.2    Nisole, S.3
  • 15
    • 0037169481 scopus 로고    scopus 로고
    • Cell surface-localized nucleolin is a eukaryotic receptor for the adhesin intimin-gamma of enterohemorrhagic Escherichia coli O157:H7
    • 4. 10.1074/jbc.M110230200
    • JF Sinclair AD O'Brien 2002 Cell surface-localized nucleolin is a eukaryotic receptor for the adhesin intimin-gamma of enterohemorrhagic Escherichia coli O157:H7 J Biol Chem 277 4 2876 2885 10.1074/jbc.M110230200
    • (2002) J Biol Chem , vol.277 , pp. 2876-2885
    • Sinclair, J.F.1    O'Brien, A.D.2
  • 16
    • 26844578691 scopus 로고    scopus 로고
    • Role of nucleolin in posttranscriptional control of MMP-9 expression
    • 1
    • M Fahling A Steege A Perlewitz 2005 Role of nucleolin in posttranscriptional control of MMP-9 expression Biochim Biophys Acta 1731 1 32 40
    • (2005) Biochim Biophys Acta , vol.1731 , pp. 32-40
    • Fahling, M.1    Steege, A.2    Perlewitz, A.3
  • 17
    • 33947609348 scopus 로고    scopus 로고
    • Overexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNA
    • 7
    • Y Otake S Soundararajan TK Sengupta 2007 Overexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNA Blood 109 7 3069 3075
    • (2007) Blood , vol.109 , pp. 3069-3075
    • Otake, Y.1    Soundararajan, S.2    Sengupta, T.K.3
  • 18
    • 42049124068 scopus 로고    scopus 로고
    • The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells
    • 7. 10.1158/0008-5472.CAN-07-5723
    • S Soundararajan W Chen EK Spicer 2008 The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells Cancer Res 68 7 2358 2365 10.1158/0008-5472.CAN-07-5723
    • (2008) Cancer Res , vol.68 , pp. 2358-2365
    • Soundararajan, S.1    Chen, W.2    Spicer, E.K.3
  • 19
    • 35548988483 scopus 로고    scopus 로고
    • Nucleolin is a receptor that mediates antiangiogenic and antitumor activity of endostatin
    • 8. 10.1182/blood-2007-01-064428
    • H Shi Y Huang H Zhou 2007 Nucleolin is a receptor that mediates antiangiogenic and antitumor activity of endostatin Blood 110 8 2899 2906 10.1182/blood-2007-01-064428
    • (2007) Blood , vol.110 , pp. 2899-2906
    • Shi, H.1    Huang, Y.2    Zhou, H.3
  • 20
    • 0032917354 scopus 로고    scopus 로고
    • FGF-2 dependent angiogenesis is a latent phenotype in basic fibroblast growth factor transgenic mice
    • 3. 10.3109/10623329909053409
    • DL Fulgham SR Widhalm S Martin 1999 FGF-2 dependent angiogenesis is a latent phenotype in basic fibroblast growth factor transgenic mice Endothelium 6 3 185 195 10.3109/10623329909053409
    • (1999) Endothelium , vol.6 , pp. 185-195
    • Fulgham, D.L.1    Widhalm, S.R.2    Martin, S.3
  • 21
    • 0034036779 scopus 로고    scopus 로고
    • An in vivo function for the transforming Myc protein: Elicitation of the angiogenic phenotype
    • 4
    • CV Ngo M Gee N Akhtar 2000 An in vivo function for the transforming Myc protein: elicitation of the angiogenic phenotype Cell Growth Differ 11 4 201 210
    • (2000) Cell Growth Differ , vol.11 , pp. 201-210
    • Ngo, C.V.1    Gee, M.2    Akhtar, N.3
  • 22
    • 39449125605 scopus 로고    scopus 로고
    • Nucleolin stabilizes Bcl-X L messenger RNA in response to UVA irradiation
    • 4. 10.1158/0008-5472.CAN-07-1927
    • J Zhang G Tsaprailis GT Bowden 2008 Nucleolin stabilizes Bcl-X L messenger RNA in response to UVA irradiation Cancer Res 68 4 1046 1054 10.1158/0008-5472.CAN-07-1927
    • (2008) Cancer Res , vol.68 , pp. 1046-1054
    • Zhang, J.1    Tsaprailis, G.2    Bowden, G.T.3
  • 23
    • 0036124520 scopus 로고    scopus 로고
    • Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors
    • 3
    • S Morikawa P Baluk T Kaidoh 2002 Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors Am J Pathol 160 3 985 1000
    • (2002) Am J Pathol , vol.160 , pp. 985-1000
    • Morikawa, S.1    Baluk, P.2    Kaidoh, T.3
  • 24
    • 0033597130 scopus 로고    scopus 로고
    • Endostatin induces endothelial cell apoptosis
    • 17. 10.1074/jbc.274.17.11721
    • M Dhanabal R Ramchandran MJ Waterman 1999 Endostatin induces endothelial cell apoptosis J Biol Chem 274 17 11721 11726 10.1074/jbc.274.17.11721
    • (1999) J Biol Chem , vol.274 , pp. 11721-11726
    • Dhanabal, M.1    Ramchandran, R.2    Waterman, M.J.3
  • 25
    • 1642307340 scopus 로고    scopus 로고
    • Endostatin's antiangiogenic signaling network
    • 5. 10.1016/S1097-2765(04)00102-9
    • A Abdollahi P Hahnfeldt C Maercker 2004 Endostatin's antiangiogenic signaling network Mol Cell 13 5 649 663 10.1016/S1097-2765(04)00102-9
    • (2004) Mol Cell , vol.13 , pp. 649-663
    • Abdollahi, A.1    Hahnfeldt, P.2    Maercker, C.3
  • 26
    • 23444460271 scopus 로고    scopus 로고
    • Antiangiogenic therapy for cancer: Current and emerging concepts
    • 4, Suppl 3. Williston Park
    • RK Jain 2005 Antiangiogenic therapy for cancer: current and emerging concepts Oncology 19 4, Suppl 3 7 16 Williston Park
    • (2005) Oncology , vol.19 , pp. 7-16
    • Jain, R.K.1
  • 27
    • 34447121919 scopus 로고    scopus 로고
    • Bevacizumab-induced transient remodeling of the vasculature in neuroblastoma xenografts results in improved delivery and efficacy of systemically administered chemotherapy
    • 13. 10.1158/1078-0432.CCR-07-0278
    • PV Dickson JB Hamner TL Sims 2007 Bevacizumab-induced transient remodeling of the vasculature in neuroblastoma xenografts results in improved delivery and efficacy of systemically administered chemotherapy Clin Cancer Res 13 13 3942 3950 10.1158/1078-0432.CCR-07-0278
    • (2007) Clin Cancer Res , vol.13 , pp. 3942-3950
    • Dickson, P.V.1    Hamner, J.B.2    Sims, T.L.3
  • 28
    • 43749112760 scopus 로고    scopus 로고
    • Vascular normalization in Rgs5-deficient tumours promotes immune destruction
    • 7193. 10.1038/nature06868
    • J Hamzah M Jugold F Kiessling 2008 Vascular normalization in Rgs5-deficient tumours promotes immune destruction Nature 453 7193 410 414 10.1038/nature06868
    • (2008) Nature , vol.453 , pp. 410-414
    • Hamzah, J.1    Jugold, M.2    Kiessling, F.3
  • 29
    • 19944422751 scopus 로고    scopus 로고
    • Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: Role of oxygenation, angiopoietin-1, and matrix metalloproteinases
    • 6
    • F Winkler SV Kozin RT Tong 2004 Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases Cancer Cell 6 6 553 563
    • (2004) Cancer Cell , vol.6 , pp. 553-563
    • Winkler, F.1    Kozin, S.V.2    Tong, R.T.3
  • 30
    • 41149138113 scopus 로고    scopus 로고
    • Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer
    • 4. 10.1038/nrc2346
    • RK Jain 2008 Lessons from multidisciplinary translational trials on anti-angiogenic therapy of cancer Nat Rev Cancer 8 4 309 316 10.1038/nrc2346
    • (2008) Nat Rev Cancer , vol.8 , pp. 309-316
    • Jain, R.K.1
  • 31
    • 36048982143 scopus 로고    scopus 로고
    • Phase II study of efficacy and safety of bevacizumab in combination with chemotherapy or erlotinib compared with chemotherapy alone for treatment of recurrent or refractory non small-cell lung cancer
    • 30. 10.1200/JCO.2007.12.3026
    • RS Herbst VJ O'Neill L Fehrenbacher 2007 Phase II study of efficacy and safety of bevacizumab in combination with chemotherapy or erlotinib compared with chemotherapy alone for treatment of recurrent or refractory non small-cell lung cancer J Clin Oncol 25 30 4743 4750 10.1200/JCO.2007.12.3026
    • (2007) J Clin Oncol , vol.25 , pp. 4743-4750
    • Herbst, R.S.1    O'Neill, V.J.2    Fehrenbacher, L.3
  • 32
    • 33845490014 scopus 로고    scopus 로고
    • Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
    • 24. 10.1056/NEJMoa061884
    • A Sandler R Gray MC Perry 2006 Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer N Engl J Med 355 24 2542 2550 10.1056/NEJMoa061884
    • (2006) N Engl J Med , vol.355 , pp. 2542-2550
    • Sandler, A.1    Gray, R.2    Perry, M.C.3


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