메뉴 건너뛰기




Volumn 34, Issue , 2011, Pages 131-152

Neuronal intrinsic mechanisms of axon regeneration

Author keywords

Axon regeneration; Axon transport; Growth cone; Optic nerve injury; Spinal cord injury

Indexed keywords

CYCLIC ADENOSINE DIPHOSPHATE RIBOSE; CYCLIC AMP; INHIBITOR OF DIFFERENTIATION 2; INTERLEUKIN 6; KRUPPEL LIKE FACTOR 4; LEUKEMIA INHIBITORY FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; NEUROTROPHIC FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; SMAD1 PROTEIN; UBIQUITIN PROTEIN LIGASE E3;

EID: 79959897174     PISSN: 0147006X     EISSN: 15454126     Source Type: Book Series    
DOI: 10.1146/annurev-neuro-061010-113723     Document Type: Article
Times cited : (354)

References (150)
  • 1
    • 77956239734 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR) activation increases axonal growth capacity of injured peripheral nerves
    • Abe N, Borson SH, Gambello MJ, Wang F, Cavalli V. 2010. Mammalian target of rapamycin (mTOR) activation increases axonal growth capacity of injured peripheral nerves. J. Biol. Chem. 285:28034-43
    • (2010) J. Biol. Chem. , vol.285 , pp. 28034-43
    • Abe, N.1    Borson, S.H.2    Gambello, M.J.3    Wang, F.4    Cavalli, V.5
  • 2
    • 33645362213 scopus 로고    scopus 로고
    • UNC-6/Netrin induces neuronal asymmetry and defines the site of axon formation
    • Adler CE, Fetter RD, Bargmann CI. 2006. UNC-6/Netrin induces neuronal asymmetry and defines the site of axon formation. Nat. Neurosci. 9:511-18
    • (2006) Nat. Neurosci. , vol.9 , pp. 511-18
    • Adler, C.E.1    Fetter, R.D.2    Bargmann, C.I.3
  • 3
    • 0019760388 scopus 로고
    • Influences of the glial environment on the elongation of axons after injury: Transplantation studies in adult rodents
    • Aguayo AJ, David S, Bray GM. 1981. Influences of the glial environment on the elongation of axons after injury: transplantation studies in adult rodents. J. Exp. Biol. 95:231-40
    • (1981) J. Exp. Biol. , vol.95 , pp. 231-40
    • Aguayo, A.J.1    David, S.2    Bray, G.M.3
  • 6
    • 28644436113 scopus 로고    scopus 로고
    • Transgenic labeling of the corticospinal tract for monitoring axonal responses to spinal cord injury
    • DOI 10.1038/nm1331
    • Bareyre FM, Kerschensteiner M, Misgeld T, Sanes JR. 2005. Transgenic labeling of the corticospinal tract for monitoring axonal responses to spinal cord injury. Nat. Med. 11:1355-60 (Pubitemid 41752918)
    • (2005) Nature Medicine , vol.11 , Issue.12 , pp. 1355-1360
    • Bareyre, F.M.1    Kerschensteiner, M.2    Misgeld, T.3    Sanes, J.R.4
  • 7
    • 0021026560 scopus 로고
    • Plasticity of the corticospinal tract following midthoracic spinal injury in the postnatal rat
    • Bernstein DR, Stelzner DJ. 1983. Plasticity of the corticospinal tract following midthoracic spinal injury in the postnatal rat. J. Comp. Neurol. 221:382-400 (Pubitemid 14221111)
    • (1983) Journal of Comparative Neurology , vol.221 , Issue.4 , pp. 382-400
    • Bernstein, D.R.1    Stelzner, D.J.2
  • 8
    • 0029986963 scopus 로고    scopus 로고
    • Peripheral nerve explants grafted into the vitreous body of the eye promote the regeneration of retinal ganglion cell axons severed in the optic nerve
    • Berry M, Carlile J, Hunter A. 1996. Peripheral nerve explants grafted into the vitreous body of the eye promote the regeneration of retinal ganglion cell axons severed in the optic nerve. J. Neurocytol. 25:147-70 (Pubitemid 26098922)
    • (1996) Journal of Neurocytology , vol.25 , Issue.2 , pp. 147-170
    • Berry, M.1    Carlile, J.2    Hunter, A.3
  • 9
    • 13944274451 scopus 로고    scopus 로고
    • Application of Rho antagonist to neuronal cell bodies promotes neurite growth in compartmented cultures and regeneration of retinal ganglion cell axons in the optic nerve of adult rats
    • DOI 10.1523/JNEUROSCI.3931-04.2005
    • Bertrand J, Winton MJ, Rodriguez-Hernandez N, Campenot RB, McKerracher L. 2005. Application of Rho antagonist to neuronal cell bodies promotes neurite growth in compartmented cultures and regeneration of retinal ganglion cell axons in the optic nerve of adult rats. J. Neurosci. 25:1113-21 (Pubitemid 40268952)
    • (2005) Journal of Neuroscience , vol.25 , Issue.5 , pp. 1113-1121
    • Bertrand, J.1    Winton, M.J.2    Rodriguez-Hernandez, N.3    Campenot, R.B.4    McKerracher, L.5
  • 10
    • 0033942954 scopus 로고    scopus 로고
    • Intercostal nerve implants transduced with an adenoviral vector encoding neurotrophin-3 promote regrowth of injured rat corticospinal tract fibers and improve hindlimb function
    • DOI 10.1006/exnr.2000.7413
    • Blits B, Dijkhuizen PA, Boer GJ, Verhaagen J. 2000. Intercostal nerve implants transduced with an adenoviral vector encoding neurotrophin-3 promote regrowth of injured rat corticospinal tract fibers and improve hindlimb function. Exp. Neurol. 164:25-37 (Pubitemid 30490719)
    • (2000) Experimental Neurology , vol.164 , Issue.1 , pp. 25-37
    • Blits, B.1    Dijkhuizen, P.A.2    Boer, G.J.3    Verhaagen, J.4
  • 11
    • 0024554491 scopus 로고
    • Extension of the critical period for developmental plasticity of the corticospinal pathway
    • DOI 10.1002/cne.902820304
    • Bregman BS, Kunkel-Bagden E, McAtee M, O'Neill A. 1989. Extensionofthe critical period for developmental plasticity of the corticospinal pathway. J. Comp. Neurol. 282:355-70 (Pubitemid 19120292)
    • (1989) Journal of Comparative Neurology , vol.282 , Issue.3 , pp. 355-370
    • Bregman, B.S.1    Kunkel-Bagden, E.2    McAtee, M.3    O'Neill, A.4
  • 13
    • 0037104645 scopus 로고    scopus 로고
    • Arginase i and polyamines act downstream from cyclic AMP in overcoming inhibition of axonal growth MAG and myelin in vitro
    • Cai D, Deng K, Mellado W, Lee J, Ratan RR, Filbin MT. 2002. Arginase I and polyamines act downstream from cyclic AMP in overcoming inhibition of axonal growth MAG and myelin in vitro. Neuron 35:711-19
    • (2002) Neuron , vol.35 , pp. 711-19
    • Cai, D.1    Deng, K.2    Mellado, W.3    Lee, J.4    Ratan, R.R.5    Filbin, M.T.6
  • 14
    • 0035399823 scopus 로고    scopus 로고
    • Neuronal cyclic AMP controls the developmental loss in ability of axons to regenerate
    • Cai D, Qiu J, Cao Z, McAtee M, Bregman BS, Filbin MT. 2001. Neuronal cyclic AMP controls the developmental loss in ability of axons to regenerate. J. Neurosci. 21:4731-39 (Pubitemid 32565631)
    • (2001) Journal of Neuroscience , vol.21 , Issue.13 , pp. 4731-4739
    • Cai, D.1    Qiu, J.2    Cao, Z.3    McAtee, M.4    Bregman, B.S.5    Filbin, M.T.6
  • 16
    • 77949452524 scopus 로고    scopus 로고
    • The PKB/AKT pathway in cancer
    • Carnero A. 2010. The PKB/AKT pathway in cancer. Curr. Pharm. Des. 16:34-44
    • (2010) Curr. Pharm. Des. , vol.16 , pp. 34-44
    • Carnero, A.1
  • 17
    • 33645777249 scopus 로고    scopus 로고
    • Regeneration of the adult central nervous system
    • Case LC, Tessier-Lavigne M. 2005. Regeneration of the adult central nervous system. Curr. Biol. 15:R749-53
    • (2005) Curr. Biol. , vol.15
    • Case, L.C.1    Tessier-Lavigne, M.2
  • 19
    • 0029089255 scopus 로고
    • Intrinsic changes in developing retinal neurons resultin regenerative failure of their axons
    • Chen DF, Jhaveri S, Schneider GE. 1995. Intrinsic changes in developing retinal neurons resultin regenerative failure of their axons. Proc. Natl. Acad. Sci. USA 92:7287-91
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7287-91
    • Chen, D.F.1    Jhaveri, S.2    Schneider, G.E.3
  • 20
    • 0001343810 scopus 로고    scopus 로고
    • Bcl-2 promotes regeneration of severed axons in mammalian CNS
    • DOI 10.1038/385434a0
    • Chen DF, Schneider GE, Martinou JC, Tonegawa S. 1997. Bcl-2 promotes regeneration of severed axons in mammalian CNS. Nature 385:434-39 (Pubitemid 27065928)
    • (1997) Nature , vol.385 , Issue.6615 , pp. 434-439
    • Chen, D.F.1    Schneider, G.E.2    Martinou, J.-C.3    Tonegawa, S.4
  • 21
    • 18844378875 scopus 로고    scopus 로고
    • The ability of axons to regenerate their growth cones depends on axonal type and age, and is regulated by calcium, cAMP and ERK
    • DOI 10.1111/j.1460-9568.2005.04066.x
    • Chierzi S, Ratto GM, Verma P, Fawcett JW. 2005. The ability of axons to regenerate their growth cones depends on axonal type and age, and is regulated by calcium, cAMP and ERK. Eur. J. Neurosci. 21:2051-62 (Pubitemid 40695229)
    • (2005) European Journal of Neuroscience , vol.21 , Issue.8 , pp. 2051-2062
    • Chierzi, S.1    Ratto, G.M.2    Verma, P.3    Fawcett, J.W.4
  • 22
    • 16344394331 scopus 로고    scopus 로고
    • Re-establishing the regenerative potential of central nervous system axons in postnatal mice
    • DOI 10.1242/jcs.01658
    • Cho KS, Yang L, Lu B, Feng Ma H, Huang X, et al. 2005. Re-establishing the regenerative potential of central nervous system axons in postnatal mice. J. Cell Sci. 118:863-72 (Pubitemid 40484879)
    • (2005) Journal of Cell Science , vol.118 , Issue.5 , pp. 863-872
    • Cho, K.-S.1    Yang, L.2    Lu, B.3    Ma, H.F.4    Huang, X.5    Pekny, M.6    Chen, D.F.7
  • 23
    • 77954480424 scopus 로고    scopus 로고
    • PTEN inhibition to facilitate intrinsic regenerative outgrowth of adult peripheral axons
    • Christie KJ, Webber CA, Martinez JA, Singh B, Zochodne DW. 2010. PTEN inhibition to facilitate intrinsic regenerative outgrowth of adult peripheral axons. J. Neurosci. 30:9306-15
    • (2010) J. Neurosci. , vol.30 , pp. 9306-15
    • Christie, K.J.1    Webber, C.A.2    Martinez, J.A.3    Singh, B.4    Zochodne, D.W.5
  • 24
    • 0014967278 scopus 로고
    • What is the signal for chromatolysis?
    • Cragg BG. 1970. What is the signal for chromatolysis? Brain Res. 23:1-21
    • (1970) Brain Res. , vol.23 , pp. 1-21
    • Cragg, B.G.1
  • 25
    • 0034619588 scopus 로고    scopus 로고
    • Co-induction of nitric oxide synthase, bcl-2 and growth-associated protein-43 in spinal motoneurons during axon regeneration in the lizard tail
    • Cristino L, Pica A, Della Corte F, Bentivoglio M. 2000. Co-induction of nitric oxide synthase, bcl-2 and growth-associated protein-43 in spinal motoneurons during axon regeneration in the lizard tail. Neuroscience 101:451-58
    • (2000) Neuroscience , vol.101 , pp. 451-58
    • Cristino, L.1    Pica, A.2    Della Corte, F.3    Bentivoglio, M.4
  • 26
    • 0019856865 scopus 로고
    • Axonal elongation into peripheral nervous system 'bridges' after central nervous system injury in adult rats
    • David S, Aguayo AJ. 1981. Axonal elongation into peripheral nervous system "bridges" after central nervous system injury in adult rats. Science 214:931-33 (Pubitemid 12220099)
    • (1981) Science , vol.214 , Issue.4523 , pp. 931-933
    • David, S.1    Aguayo, A.J.2
  • 27
    • 68049147011 scopus 로고    scopus 로고
    • Increased synthesis of spermidine as a result of upregulation of arginase i promotes axonal regeneration in culture and in vivo
    • Deng K, He H, Qiu J, Lorber B, Bryson JB, Filbin MT. 2009. Increased synthesis of spermidine as a result of upregulation of arginase I promotes axonal regeneration in culture and in vivo. J. Neurosci. 29:9545-52
    • (2009) J. Neurosci. , vol.29 , pp. 9545-52
    • Deng, K.1    He, H.2    Qiu, J.3    Lorber, B.4    Bryson, J.B.5    Filbin, M.T.6
  • 28
    • 77955416137 scopus 로고    scopus 로고
    • Electrical activity suppresses axon growth through Ca(v)1.2 channels in adult primary sensory neurons
    • Enes J, Langwieser N, Ruschel J, Carballosa-Gonzalez MM, Klug A, et al. 2010. Electrical activity suppresses axon growth through Ca(v)1.2 channels in adult primary sensory neurons. Curr. Biol. 20:1154-64
    • (2010) Curr. Biol. , vol.20 , pp. 1154-64
    • Enes, J.1    Langwieser, N.2    Ruschel, J.3    Carballosa-Gonzalez, M.M.4    Klug, A.5
  • 29
    • 33846971984 scopus 로고    scopus 로고
    • Formation of microtubule-based traps controls the sorting and concentration of vesicles to restricted sites of regenerating neurons after axotomy
    • Erez H, Malkinson G, Prager-Khoutorsky M, De Zeeuw CI, Hoogenraad CC, Spira ME. 2007. Formation of microtubule-based traps controls the sorting and concentration of vesicles to restricted sites of regenerating neurons after axotomy. J. Cell Biol. 176:497-507
    • (2007) J. Cell Biol. , vol.176 , pp. 497-507
    • Erez, H.1    Malkinson, G.2    Prager-Khoutorsky, M.3    De Zeeuw, C.I.4    Hoogenraad, C.C.5    Spira, M.E.6
  • 30
    • 0032703535 scopus 로고    scopus 로고
    • Influence of the axotomy to cell body distance in rat rubrospinal and spinal motoneurons: Differential regulation of GAP-43, tubulins, and neurofilament-M
    • DOI 10.1002/(SI CI)1096-98 61(19991 129)414:4<49 5::AID-CN E6>3.0.CO;2-S
    • Fernandes KJ, Fan DP, Tsui BJ, Cassar SL, Tetzlaff W. 1999. Influence of the axotomy to cell body distance in rat rubrospinal and spinal motoneurons: differential regulation of GAP-43, tubulins, and neurofilament-M. J. Comp. Neurol. 414:495-510 (Pubitemid 29506362)
    • (1999) Journal of Comparative Neurology , vol.414 , Issue.4 , pp. 495-510
    • Fernandes, K.J.L.1    Fan, D.-P.2    Tsui, B.J.3    Cassar, S.L.4    Tetzlaff, W.5
  • 31
    • 0025483122 scopus 로고
    • Effects of patterned electrical activity on neurite outgrowth from mouse sensory neurons
    • Fields RD, Neale EA, Nelson PG. 1990. Effects of patterned electrical activity on neurite outgrowth from mouse sensory neurons. J. Neurosci. 10:2950-64
    • (1990) J. Neurosci. , vol.10 , pp. 2950-64
    • Fields, R.D.1    Neale, E.A.2    Nelson, P.G.3
  • 32
    • 0035690364 scopus 로고    scopus 로고
    • Lens-injury-stimulated axonal regeneration throughout the optic pathway of adult rats
    • DOI 10.1006/exnr.2001.7822
    • Fischer D, Heiduschka P, Thanos S. 2001. Lens-injury-stimulated axonal regeneration throughout the optic pathway of adult rats. Exp. Neurol. 172: 257-72 (Pubitemid 34075076)
    • (2001) Experimental Neurology , vol.172 , Issue.2 , pp. 257-272
    • Fischer, D.1    Heiduschka, P.2    Thanos, S.3
  • 33
    • 33749002853 scopus 로고    scopus 로고
    • Recapitulate development to promote axonal regeneration: Good or bad approach?
    • DOI 10.1098/rstb.2006.1885
    • Filbin MT. 2006. Recapitulate development to promote axonal regeneration: good or bad approach? Philos. Trans. R. Soc. Lond. B Biol. Sci. 361:1565-74 (Pubitemid 44450211)
    • (2006) Philosophical Transactions of the Royal Society B: Biological Sciences , vol.361 , Issue.1473 , pp. 1565-1574
    • Filbin, M.T.1
  • 34
    • 0037804784 scopus 로고    scopus 로고
    • Vesicle-mediated restoration of a plasmalemmal barrier in severed axons
    • Fishman HM, Bittner GD. 2003. Vesicle-mediated restoration of a plasmalemmal barrier in severed axons. News Physiol. Sci. 18:115-8 (Pubitemid 36782801)
    • (2003) News in Physiological Sciences , vol.18 , Issue.JUNE , pp. 115-118
    • Fishman, H.M.1    Bittner, G.D.2
  • 35
    • 38649112309 scopus 로고    scopus 로고
    • CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure
    • DOI 10.1016/j.expneurol.2007.05.014, PII S0014488607002130
    • Fitch MT, Silver J. 2008. CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure. Exp. Neurol. 209:294-301 (Pubitemid 351174127)
    • (2008) Experimental Neurology , vol.209 , Issue.2 , pp. 294-301
    • Fitch, M.T.1    Silver, J.2
  • 37
    • 42549166077 scopus 로고    scopus 로고
    • Distinct cellular and molecular mechanisms mediate initial axon development and adult-stage axon regeneration in C. elegans
    • DOI 10.1242/dev.013995
    • Gabel CV, Antoine F, Chuang CF, Samuel AD, Chang C. 2008. Distinct cellular and molecular mechanisms mediate initial axon development and adult-stage axon regeneration in C. elegans. Development 135:1129-36 (Pubitemid 351578141)
    • (2008) Development , vol.135 , Issue.6 , pp. 1129-1136
    • Gabel, C.V.1    Antonie, F.2    Chuang, C.-F.3    Samuel, A.D.T.4    Chang, C.5
  • 38
    • 0027970246 scopus 로고
    • Delayed macrophage responses and myelin clearance during Wallerian degeneration in the central nervous system: The dorsal radiculotomy model
    • DOI 10.1006/exnr.1994.1164
    • George R, Griffin JW. 1994. Delayed macrophage responses and myelin clearance during Wallerian degeneration in the central nervous system: the dorsal radiculotomy model. Exp. Neurol. 129:225-36 (Pubitemid 24365941)
    • (1994) Experimental Neurology , vol.129 , Issue.2 , pp. 225-236
    • George, R.1    Griffin, J.W.2
  • 39
    • 77749313490 scopus 로고    scopus 로고
    • Calcium and cyclic AMP promote axonal regeneration in Caenorhabditis elegans and require DLK-1 kinase
    • Ghosh-Roy A, Wu Z, Goncharov A, Jin Y, Chisholm AD. 2010. Calcium and cyclic AMP promote axonal regeneration in Caenorhabditis elegans and require DLK-1 kinase. J. Neurosci. 30:3175-83
    • (2010) J. Neurosci. , vol.30 , pp. 3175-83
    • Ghosh-Roy, A.1    Wu, Z.2    Goncharov, A.3    Jin, Y.4    Chisholm, A.D.5
  • 40
    • 23244441099 scopus 로고    scopus 로고
    • Growth and survival signals controlling sympathetic nervous system development
    • DOI 10.1146/annurev.neuro.28.061604.135659
    • Glebova NO, Ginty DD. 2005. Growth and survival signals controlling sympathetic nervous system development. Annu. Rev. Neurosci. 28:191-222 (Pubitemid 41098904)
    • (2005) Annual Review of Neuroscience , vol.28 , pp. 191-222
    • Glebova, N.O.1    Ginty, D.D.2
  • 41
    • 0034078885 scopus 로고    scopus 로고
    • The relationship between neuronal survival and regeneration
    • DOI 10.1146/annurev.neuro.23.1.579
    • Goldberg JL, Barres BA. 2000. The relationship between neuronal survival and regeneration. Annu. Rev. Neurosci. 23:579-612 (Pubitemid 30350055)
    • (2000) Annual Review of Neuroscience , vol.23 , pp. 579-612
    • Goldberg, J.L.1    Barres, B.A.2
  • 42
    • 0037186139 scopus 로고    scopus 로고
    • Retinal ganglion cells do not extend axons by default: Promotion by neurotrophic signaling and electrical activity
    • DOI 10.1016/S0896-6273(02)00602-5
    • Goldberg JL, Espinosa JS, Xu Y, Davidson N, Kovacs GT, Barres BA. 2002a. Retinal ganglion cells do not extend axons by default: promotion by neurotrophic signaling and electrical activity. Neuron 33:689-702 (Pubitemid 34219241)
    • (2002) Neuron , vol.33 , Issue.5 , pp. 689-702
    • Goldberg, J.L.1    Espinosa, J.S.2    Xu, Y.3    Davidson, N.4    Kovacs, G.T.A.5    Barres, B.A.6
  • 43
    • 0037036144 scopus 로고    scopus 로고
    • Amacrine-signaled loss of intrinsic axon growth ability by retinal ganglion cells
    • DOI 10.1126/science.1068428
    • Goldberg JL, Klassen MP, Hua Y, Barres BA. 2002b. Amacrine-signaled loss of intrinsic axon growth ability by retinal ganglion cells. Science 296:1860-4 (Pubitemid 34596271)
    • (2002) Science , vol.296 , Issue.5574 , pp. 1860-1864
    • Goldberg, J.L.1    Klassen, M.P.2    Hua, Y.3    Barres, B.A.4
  • 44
    • 0022884909 scopus 로고
    • On the development of the pyramidal tract in the rat. II. An anterograde tracer study of the outgrowth of the corticospinal fibers
    • DOI 10.1007/BF00315460
    • Gribnau AA, de Kort EJ, Dederen PJ, Nieuwenhuys R. 1986. On the development of the pyramidal tract in the rat. II. An anterograde tracer study of the outgrowth of the corticospinal fibers. Anat. Embryol. (Berl.) 175:101-10 (Pubitemid 17044374)
    • (1986) Anatomy and Embryology , vol.175 , Issue.1 , pp. 101-110
    • Gribnau, A.A.M.1    De Kort, E.J.M.2    Dederen, P.J.W.C.3    Nieuwenhuys, R.4
  • 45
    • 0031408944 scopus 로고    scopus 로고
    • Robust growth of chronically injured spinal cord axons induced by grafts of genetically modified NGF-secreting cells
    • DOI 10.1006/exnr.1997.6704
    • Grill RJ, Blesch A, Tuszynski MH. 1997. Robust growth of chronically injured spinal cord axons induced by grafts of genetically modified NGF-secreting cells. Exp. Neurol. 148:444-52 (Pubitemid 28068840)
    • (1997) Experimental Neurology , vol.148 , Issue.2 , pp. 444-452
    • Grill, R.J.1    Blesch, A.2    Tuszynski, M.H.3
  • 46
    • 34347220473 scopus 로고    scopus 로고
    • Defining the Role of mTOR in Cancer
    • DOI 10.1016/j.ccr.2007.05.008, PII S1535610807001511
    • Guertin DA, Sabatini DM. 2007. Defining the role of mTOR in cancer. Cancer Cell 12:9-22 (Pubitemid 47001784)
    • (2007) Cancer Cell , vol.12 , Issue.1 , pp. 9-22
    • Guertin, D.A.1    Sabatini, D.M.2
  • 47
    • 77950863408 scopus 로고    scopus 로고
    • The role of local protein synthesis and degradation in axon regeneration
    • Gumy LF, Tan CL, Fawcett JW. 2010. The role of local protein synthesis and degradation in axon regeneration. Exp. Neurol. 223:28-37
    • (2010) Exp. Neurol. , vol.223 , pp. 28-37
    • Gumy, L.F.1    Tan, C.L.2    Fawcett, J.W.3
  • 50
    • 4544335401 scopus 로고    scopus 로고
    • Cyclic AMP elevates tubulin expression without increasing intrinsic axon growth capacity
    • DOI 10.1016/j.expneurol.2004.03.010, PII S0014488604001013
    • Han PJ, Shukla S, Subramanian PS, Hoffman PN. 2004. Cyclic AMP elevates tubulin expression without increasing intrinsic axon growth capacity. Exp. Neurol. 189:293-302 (Pubitemid 39221823)
    • (2004) Experimental Neurology , vol.189 , Issue.2 , pp. 293-302
    • Han, P.J.1    Shukla, S.2    Subramanian, P.S.3    Hoffman, P.N.4
  • 52
    • 33746271855 scopus 로고    scopus 로고
    • Can regenerating axons recapitulate developmental guidance during recovery from spinal cord injury?
    • DOI 10.1038/nrn1957, PII NRN1957
    • Harel NY, Strittmatter SM. 2006. Can regenerating axons recapitulate developmental guidance during recovery from spinal cord injury? Nat. Rev. Neurosci. 7:603-16 (Pubitemid 44106743)
    • (2006) Nature Reviews Neuroscience , vol.7 , Issue.8 , pp. 603-616
    • Harel, N.Y.1    Strittmatter, S.M.2
  • 53
    • 38649110471 scopus 로고    scopus 로고
    • Neuroprotective and axon growth promoting effects of intraocular inflammation do not depend on oncomodulin or the presence of large numbers of activated macrophages
    • DOI 10.1016/j.expneurol.2007.09.020, PII S0014488607003640
    • Hauk TG, Muller A, Lee J, Schwendener R, Fischer D. 2008. Neuroprotective and axon growth promoting effects of intraocular inflammation do not depend on oncomodulin or the presence of large numbers of activated macrophages. Exp. Neurol. 209:469-82 (Pubitemid 351174139)
    • (2008) Experimental Neurology , vol.209 , Issue.2 , pp. 469-482
    • Hauk, T.G.1    Muller, A.2    Lee, J.3    Schwendener, R.4    Fischer, D.5
  • 54
    • 0034845513 scopus 로고    scopus 로고
    • Degeneration and sprouting of identified descending supraspinal axons after contusive spinal cord injury in the rat
    • DOI 10.1006/exnr.2001.7734
    • Hill CE, Beattie MS, Bresnahan JC. 2001. Degeneration and sprouting of identified descending supraspinal axons after contusive spinal cord injury in the rat. Exp. Neurol. 171:153-69 (Pubitemid 32848454)
    • (2001) Experimental Neurology , vol.171 , Issue.1 , pp. 153-169
    • Hill, C.E.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 55
    • 77950859906 scopus 로고    scopus 로고
    • A conditioning lesion induces changes in gene expression and axonal transport that enhance regeneration by increasing the intrinsic growth state of axons
    • Hoffman PN. 2010. A conditioning lesion induces changes in gene expression and axonal transport that enhance regeneration by increasing the intrinsic growth state of axons. Exp. Neurol. 223:11-18
    • (2010) Exp. Neurol. , vol.223 , pp. 11-18
    • Hoffman, P.N.1
  • 57
    • 57449092483 scopus 로고    scopus 로고
    • IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury
    • Hollis ER 2nd, Lu P, Blesch A, Tuszynski MH. 2009b. IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury. Exp. Neurol. 215:53-59
    • (2009) Exp. Neurol. , vol.215 , pp. 53-59
    • Hollis II, E.R.1    Lu, P.2    Blesch, A.3    Tuszynski, M.H.4
  • 58
    • 0026077673 scopus 로고
    • Initial stages of retinofugal axon development in the hamster: Evidence for two distinct modes of growth
    • Jhaveri S, Edwards MA, Schneider GE. 1991. Initial stages of retinofugal axon development in the hamster: evidence for two distinct modes of growth. Exp. Brain Res. 87:371-82
    • (1991) Exp. Brain Res. , vol.87 , pp. 371-82
    • Jhaveri, S.1    Edwards, M.A.2    Schneider, G.E.3
  • 59
    • 0028801172 scopus 로고
    • Directional regrowth of lesioned corticospinal tract axons in adult rat spinal cord
    • Joosten EA, Bar PR, Gispen WH. 1995. Directional regrowth of lesioned corticospinal tract axons in adult rat spinal cord. Neuroscience 69:619-26
    • (1995) Neuroscience , vol.69 , pp. 619-26
    • Joosten, E.A.1    Bar, P.R.2    Gispen, W.H.3
  • 60
    • 68549094301 scopus 로고    scopus 로고
    • Local calcium-dependent mechanisms determine whether a cut axonal end assembles a retarded endbulb or competent growth cone
    • Kamber D, Erez H, Spira ME. 2009. Local calcium-dependent mechanisms determine whether a cut axonal end assembles a retarded endbulb or competent growth cone. Exp. Neurol. 219:112-25
    • (2009) Exp. Neurol. , vol.219 , pp. 112-25
    • Kamber, D.1    Erez, H.2    Spira, M.E.3
  • 61
    • 1142274208 scopus 로고    scopus 로고
    • Cdh1-APC controls axonal growth and patterning in the mammalian brain
    • DOI 10.1126/science.1093712
    • Konishi Y, Stegmuller J, Matsuda T, Bonni S, Bonni A. 2004. Cdh1-APC controls axonal growth and patterning in the mammalian brain. Science 303:1026-30 (Pubitemid 38209709)
    • (2004) Science , vol.303 , Issue.5660 , pp. 1026-1030
    • Konishi, Y.1    Stegmuller, J.2    Matsuda, T.3    Bonni, S.4    Bonni, A.5
  • 62
    • 0031371743 scopus 로고    scopus 로고
    • A subtractive cDNA Library from an identified regenerating neuron is enriched in sequences up-regulated during nerve regeneration
    • DOI 10.1007/BF02480373
    • Korneev S, Fedorov A, Collins R, Blackshaw SE, Davies JA. 1997. A subtractive cDNA library from an identified regenerating neuron is enriched in sequences up-regulated during nerve regeneration. Invert. Neurosci. 3:185-92 (Pubitemid 28433015)
    • (1997) Invertebrate Neuroscience , vol.3 , Issue.2-3 , pp. 185-192
    • Korneev, S.1    Fedorov, A.2    Collins, R.3    Blackshaw, S.E.4    Davies, J.A.5
  • 64
    • 0032472832 scopus 로고    scopus 로고
    • Mechanisms of enhancement of neurite regeneration in vitro following a conditioning sciatic nerve lesion
    • DOI 10.1002/(SICI)1 096-9861(199 80202)391:1<1 1::AID-CN E2>3.0.CO;2-U
    • Lankford KL, Waxman SG, Kocsis JD. 1998. Mechanisms of enhancement of neurite regeneration in vitro following a conditioning sciatic nerve lesion. J. Comp. Neurol. 391:11-29 (Pubitemid 28109616)
    • (1998) Journal of Comparative Neurology , vol.391 , Issue.1 , pp. 11-29
    • Lankford, K.L.1    Waxman, S.G.2    Kocsis, J.D.3
  • 65
    • 0014288359 scopus 로고
    • Axoplasmic transport of labeled proteins in rat ventral motoneurons
    • Lasek RJ. 1968. Axoplasmic transport of labeled proteins in rat ventral motoneurons. Exp. Neurol. 21:41-51
    • (1968) Exp. Neurol. , vol.21 , pp. 41-51
    • Lasek, R.J.1
  • 66
    • 0000686833 scopus 로고
    • The neuronal cytoskeleton, axonal transport and axonal growth
    • ed. R Goldman, T Pollard, J Rosenbaum Cold Spring Harbor, NY: Cold Spring Harbor Lab. Press
    • Lasek RJ, Hoffman PN. 1976. The neuronal cytoskeleton, axonal transport and axonal growth. In Cold Spring Harbor Laboratory Conference on Cell Proliferation, Cell Motility. Vol. 3, ed. R Goldman, T Pollard, J Rosenbaum, pp. 1021-49. Cold Spring Harbor, NY: Cold Spring Harbor Lab. Press
    • (1976) Cold Spring Harbor Laboratory Conference on Cell Proliferation, Cell Motility. , vol.3 , pp. 1021-49
    • Lasek, R.J.1    Hoffman, P.N.2
  • 68
    • 33748299407 scopus 로고    scopus 로고
    • AAV-mediated expression of CNTF promotes long-term survival and regeneration of adult rat retinal ganglion cells
    • DOI 10.1038/sj.gt.3302791, PII 3302791
    • Leaver SG, Cui Q, Plant GW, Arulpragasam A, Hisheh S, et al. 2006. AAV-mediated expression of CNTF promotes long-term survival and regeneration of adult rat retinal ganglion cells. Gene Ther. 13:1328-41 (Pubitemid 44323689)
    • (2006) Gene Therapy , vol.13 , Issue.18 , pp. 1328-1341
    • Leaver, S.G.1    Cui, Q.2    Plant, G.W.3    Arulpragasam, A.4    Hisheh, S.5    Verhaagen, J.6    Harvey, A.R.7
  • 69
    • 70449640540 scopus 로고    scopus 로고
    • Neuroprotective and axon growth-promoting effects following inflammatory stimulation on mature retinal ganglion cells in mice depend on ciliary neurotrophic factor and leukemia inhibitory factor
    • Leibinger M, Muller A, Andreadaki A, Hauk TG, Kirsch M, Fischer D. 2009. Neuroprotective and axon growth-promoting effects following inflammatory stimulation on mature retinal ganglion cells in mice depend on ciliary neurotrophic factor and leukemia inhibitory factor. J. Neurosci. 29:14334-41
    • (2009) J. Neurosci. , vol.29 , pp. 14334-41
    • Leibinger, M.1    Muller, A.2    Andreadaki, A.3    Hauk, T.G.4    Kirsch, M.5    Fischer, D.6
  • 70
    • 0034659957 scopus 로고    scopus 로고
    • Lens injury stimulates axon regeneration in the mature rat optic nerve
    • Leon S, Yin Y, Nguyen J, Irwin N, Benowitz LI. 2000. Lens injury stimulates axon regeneration in the mature rat optic nerve. J. Neurosci. 20:4615-26 (Pubitemid 30396627)
    • (2000) Journal of Neuroscience , vol.20 , Issue.12 , pp. 4615-4626
    • Leon, S.1    Yin, Y.2    Nguyen, J.3    Irwin, N.4    Benowitz, L.I.5
  • 71
    • 0030769193 scopus 로고    scopus 로고
    • Repair of adult rat corticospinal tract by transplants of olfactory ensheathing cells
    • DOI 10.1126/science.277.5334.2000
    • Li Y, Field PM, Raisman G. 1997. Repair of adult rat corticospinal tract by transplants of olfactory ensheathing cells. Science 277:2000-2 (Pubitemid 27449143)
    • (1997) Science , vol.277 , Issue.5334 , pp. 2000-2002
    • Li, Y.1    Field, P.M.2    Raisman, G.3
  • 72
    • 0032535687 scopus 로고    scopus 로고
    • Regeneration of adult rat corticospinal axons induced by transplanted olfactory ensheathing cells
    • Li Y, Field PM, Raisman G. 1998. Regeneration of adult rat corticospinal axons induced by transplanted olfactory ensheathing cells. J. Neurosci. 18:10514-24 (Pubitemid 29016571)
    • (1998) Journal of Neuroscience , vol.18 , Issue.24 , pp. 10514-10524
    • Li, Y.1    Field, P.M.2    Raisman, G.3
  • 73
    • 0029089633 scopus 로고
    • Sprouts from cut corticospinal axons persist in the presence of astrocytic scarring in long-term lesions of the adult rat spinal cord
    • Li Y, Raisman G. 1995. Sprouts from cut corticospinal axons persist in the presence of astrocytic scarring in long-term lesions of the adult rat spinal cord. Exp. Neurol. 134:102-11
    • (1995) Exp. Neurol. , vol.134 , pp. 102-11
    • Li, Y.1    Raisman, G.2
  • 74
    • 0015197354 scopus 로고
    • The axon reaction: A review of the principal features of perikaryal responses to axon injury
    • Lieberman AR. 1971. The axon reaction: a review of the principal features of perikaryal responses to axon injury. Int. Rev. Neurobiol. 14:49-124
    • (1971) Int. Rev. Neurobiol. , vol.14 , pp. 49-124
    • Lieberman, A.R.1
  • 75
    • 7244240786 scopus 로고    scopus 로고
    • Inhibition of c-Jun phosphorylation reduces axonal outgrowth of adult rat nodose ganglia and dorsal root ganglia sensory neurons
    • DOI 10.1016/j.mcn.2004.07.001, PII S1044743104001617
    • Lindwall C, Dahlin L, Lundborg G, Kanje M. 2004. Inhibition of c-Jun phosphorylation reduces axonal outgrowth of adult rat nodose ganglia and dorsal root ganglia sensory neurons. Mol. Cell Neurosci. 27:267-79 (Pubitemid 39433841)
    • (2004) Molecular and Cellular Neuroscience , vol.27 , Issue.3 , pp. 267-279
    • Lindwall, C.1    Dahlin, L.2    Lundborg, G.3    Kanje, M.4
  • 76
    • 77956187905 scopus 로고    scopus 로고
    • PTEN deletion enhances the regenerative ability of adult corticospinal neurons
    • Liu K, Lu Y, Lee JK, Samara R, Willenberg R, et al. 2010. PTEN deletion enhances the regenerative ability of adult corticospinal neurons. Nat. Neurosci. 13:1075-81
    • (2010) Nat. Neurosci. , vol.13 , pp. 1075-81
    • Liu, K.1    Lu, Y.2    Lee, J.K.3    Samara, R.4    Willenberg, R.5
  • 77
    • 0035463768 scopus 로고    scopus 로고
    • Different signaling pathways mediate regenerative versus developmental sensory axon growth
    • Liu RY, Snider WD. 2001. Different signaling pathways mediate regenerative versus developmental sensory axon growth. J. Neurosci. 21:RC164
    • (2001) J. Neurosci. , vol.21
    • Liu, R.Y.1    Snider, W.D.2
  • 78
    • 71149108631 scopus 로고    scopus 로고
    • Mst3b, an Ste20-like kinase, regulates axon regeneration in mature CNS and PNS pathways
    • Lorber B, Howe ML, Benowitz LI, Irwin N. 2009. Mst3b, an Ste20-like kinase, regulates axon regeneration in mature CNS and PNS pathways. Nat. Neurosci. 12:1407-14
    • (2009) Nat. Neurosci. , vol.12 , pp. 1407-14
    • Lorber, B.1    Howe, M.L.2    Benowitz, L.I.3    Irwin, N.4
  • 79
    • 3242711266 scopus 로고    scopus 로고
    • Combinatorial therapy with neurotrophins and cAMP promotes axonal regeneration beyond sites of spinal cord injury
    • DOI 10.1523/JNEUROSCI.1492-04.2004
    • Lu P, Yang H, Jones LL, Filbin MT, Tuszynski MH. 2004. Combinatorial therapy with neurotrophins and cAMP promotes axonal regeneration beyond sites of spinal cord injury. J. Neurosci. 24:6402-9 (Pubitemid 38944231)
    • (2004) Journal of Neuroscience , vol.24 , Issue.28 , pp. 6402-6409
    • Lu, P.1    Yang, H.2    Jones, L.L.3    Filbin, M.T.4    Tuszynski, M.H.5
  • 80
    • 0142227019 scopus 로고    scopus 로고
    • Targeting the PI3K-Akt pathway in human cancer: Rationale and promise
    • DOI 10.1016/S1535-6108(03)00248-4
    • Luo J, Manning BD, Cantley LC. 2003. Targeting the PI3K-Akt pathway in human cancer: rationale and promise. Cancer Cell 4:257-62 (Pubitemid 37329790)
    • (2003) Cancer Cell , vol.4 , Issue.4 , pp. 257-262
    • Luo, J.1    Manning, B.D.2    Cantley, L.C.3
  • 81
    • 0037014483 scopus 로고    scopus 로고
    • Raf and Akt mediate distinct aspects of sensory axon growth
    • DOI 10.1016/S0896-6273(02)00752-3
    • Markus A, Zhong J, Snider WD. 2002. Raf and akt mediate distinct aspects of sensory axon growth. Neuron 35:65-76 (Pubitemid 34804323)
    • (2002) Neuron , vol.35 , Issue.1 , pp. 65-76
    • Markus, A.1    Zhong, J.2    Snider, W.D.3
  • 82
    • 0026764224 scopus 로고
    • Slow transport of the cytoskeleton after axonal injury
    • McKerracher L, Hirscheimer A. 1992. Slow transport of the cytoskeleton after axonal injury. J. Neurobiol. 23:568-78
    • (1992) J. Neurobiol. , vol.23 , pp. 568-78
    • McKerracher, L.1    Hirscheimer, A.2
  • 83
    • 0025471214 scopus 로고
    • Selective impairment of slow axonal transport after optic nerve injury in adult rats
    • McKerracher L, Vidal-Sanz M, Essagian C, Aguayo AJ. 1990. Selective impairment of slow axonal transport after optic nerve injury in adult rats. J. Neurosci. 10:2834-41
    • (1990) J. Neurosci. , vol.10 , pp. 2834-41
    • McKerracher, L.1    Vidal-Sanz, M.2    Essagian, C.3    Aguayo, A.J.4
  • 84
    • 0017713650 scopus 로고
    • Axonal regeneration in the rat sciatic nerve: Effect of a conditioning lesion and of dbcAMP
    • DOI 10.1016/0006-8993(77)90193-7
    • McQuarrie IG, Grafstein B, Gershon MD. 1977. Axonal regeneration in the rat sciatic nerve: effect of a conditioning lesion and of dbcAMP. Brain Res. 132:443-53 (Pubitemid 8166017)
    • (1977) Brain Research , vol.132 , Issue.3 , pp. 443-453
    • McQuarrie, I.G.1    Grafstein, B.2    Gershon, M.D.3
  • 86
    • 33748681723 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-3 suppresses the ability of activated signal transducer and activator of transcription-3 to stimulate neurite growth in rat primary sensory neurons
    • DOI 10.1523/JNEUROSCI.2160-06.2006
    • Miao T, Wu D, Zhang Y, Bo X, Subang MC, et al. 2006. Suppressor of cytokine signaling-3 suppresses the ability of activated signal transducer and activator of transcription-3 to stimulate neurite growth in rat primary sensory neurons. J. Neurosci. 26:9512-19 (Pubitemid 44396864)
    • (2006) Journal of Neuroscience , vol.26 , Issue.37 , pp. 9512-9519
    • Miao, T.1    Wu, D.2    Zhang, Y.3    Bo, X.4    Subang, M.C.5    Wang, P.6    Richardson, P.M.7
  • 87
    • 70349884323 scopus 로고    scopus 로고
    • KLF family members regulate intrinsic axon regeneration ability
    • Moore DL, Blackmore MG, Hu Y, Kaestner KH, Bixby JL, et al. 2009. KLF family members regulate intrinsic axon regeneration ability. Science 326:298-301
    • (2009) Science , vol.326 , pp. 298-301
    • Moore, D.L.1    Blackmore, M.G.2    Hu, Y.3    Kaestner, K.H.4    Bixby, J.L.5
  • 88
    • 36749004288 scopus 로고    scopus 로고
    • Astrocyte-derived CNTF switches mature RGCs to a regenerative state following inflammatory stimulation
    • DOI 10.1093/brain/awm257
    • Muller A, Hauk TG, Fischer D. 2007. Astrocyte-derived CNTF switches mature RGCs to a regenerative state following inflammatory stimulation. Brain 130:3308-20 (Pubitemid 350209074)
    • (2007) Brain , vol.130 , Issue.12 , pp. 3308-3320
    • Muller, A.1    Hauk, T.G.2    Fischer, D.3
  • 90
    • 0036786634 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor prevents axotomized retinal ganglion cell death through MAPK and PI3K signaling pathways
    • Nakazawa T, Tamai M, Mori N. 2002. Brain-derived neurotrophic factor prevents axotomized retinal ganglion cell death through MAPK and PI3K signaling pathways. Invest. Ophthalmol. Vis. Sci. 43:3319-26
    • (2002) Invest. Ophthalmol. Vis. Sci. , vol.43 , pp. 3319-26
    • Nakazawa, T.1    Tamai, M.2    Mori, N.3
  • 91
    • 0033137077 scopus 로고    scopus 로고
    • Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury
    • DOI 10.1016/S0896-6273(00)80755-2
    • Neumann S, Woolf CJ. 1999. Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury. Neuron 23:83-91 (Pubitemid 29262466)
    • (1999) Neuron , vol.23 , Issue.1 , pp. 83-91
    • Neumann, S.1    Woolf, C.J.2
  • 92
    • 33750492639 scopus 로고    scopus 로고
    • IGF-I specifically enhances axon outgrowth of corticospinal motor neurons
    • DOI 10.1038/nn1789, PII NN1789
    • Ozdinler PH, Macklis JD. 2006. IGF-I specifically enhances axon outgrowth of corticospinal motor neurons. Nat. Neurosci. 9:1371-81 (Pubitemid 44646209)
    • (2006) Nature Neuroscience , vol.9 , Issue.11 , pp. 1371-1381
    • Ozdinler, P.H.1    Macklis, J.D.2
  • 93
    • 10044292873 scopus 로고    scopus 로고
    • Cellular mechanisms associated with spontaneous and ciliary neurotrophic factor-cAMP-induced survival and axonal regeneration of adult retinal ganglion cells
    • DOI 10.1523/JNEUROSCI.3532-04.2004
    • Park K, Luo JM, Hisheh S, Harvey AR, Cui Q. 2004. Cellular mechanisms associated with spontaneous and ciliary neurotrophic factor-cAMP-induced survival and axonal regeneration of adult retinal ganglion cells. J. Neurosci. 24:10806-15 (Pubitemid 39602392)
    • (2004) Journal of Neuroscience , vol.24 , Issue.48 , pp. 10806-10815
    • Park, K.1    Luo, J.-M.2    Hisheh, S.3    Harvey, A.R.4    Cui, Q.5
  • 94
    • 67349169929 scopus 로고    scopus 로고
    • Cytokine-induced SOCS expression is inhibited by cAMP analogue: Impact on regeneration in injured retina
    • Park KK, Hu Y, Muhling J, Pollett MA, Dallimore EJ, et al. 2009. Cytokine-induced SOCS expression is inhibited by cAMP analogue: impact on regeneration in injured retina. Mol. Cell Neurosci. 41:313-24
    • (2009) Mol. Cell Neurosci. , vol.41 , pp. 313-24
    • Park, K.K.1    Hu, Y.2    Muhling, J.3    Pollett, M.A.4    Dallimore, E.J.5
  • 96
    • 55849108858 scopus 로고    scopus 로고
    • Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway
    • Park KK, Liu K, Hu Y, Smith PD, Wang C, et al. 2008. Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway. Science 322:963-66
    • (2008) Science , vol.322 , pp. 963-66
    • Park, K.K.1    Liu, K.2    Hu, Y.3    Smith, P.D.4    Wang, C.5
  • 97
    • 14644404885 scopus 로고    scopus 로고
    • Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve
    • DOI 10.1016/j.neuron.2005.01.023
    • Perlson E, Hanz S, Ben-Yaakov K, Segal-Ruder Y, Seger R, Fainzilber M. 2005. Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve. Neuron 45:715-26 (Pubitemid 40320706)
    • (2005) Neuron , vol.45 , Issue.5 , pp. 715-726
    • Perlson, E.1    Hanz, S.2    Ben-Yaakov, K.3    Segal-Ruder, Y.4    Seger, R.5    Fainzilber, M.6
  • 98
    • 33645046628 scopus 로고    scopus 로고
    • Synergistic action of brain-derived neurotrophic factor and lens injury promotes retinal ganglion cell survival, but leads to optic nerve dystrophy in vivo
    • Pernet V, Di Polo A. 2006. Synergistic action of brain-derived neurotrophic factor and lens injury promotes retinal ganglion cell survival, but leads to optic nerve dystrophy in vivo. Brain 129:1014-26
    • (2006) Brain , vol.129 , pp. 1014-26
    • Pernet, V.1    Di Polo, A.2
  • 99
    • 16244388563 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase 1/2 mediates survival, but not axon regeneration, of adult injured central nervous system neurons in vivo
    • DOI 10.1111/j.1471-4159.2005.03002.x
    • Pernet V, Hauswirth WW, Di Polo A. 2005. Extracellular signal-regulated kinase 1/2 mediates survival, but not axon regeneration, of adult injured central nervous system neurons in vivo. J. Neurochem. 93:72-83 (Pubitemid 40463517)
    • (2005) Journal of Neurochemistry , vol.93 , Issue.1 , pp. 72-83
    • Pernet, V.1    Hauswirth, W.W.2    Di Polo, A.3
  • 100
    • 0037396474 scopus 로고    scopus 로고
    • Chondroitin sulphate proteoglycans in the central nervous system: Changes and synthesis after injury
    • DOI 10.1042/BST0310335
    • Properzi F, Asher RA, Fawcett JW. 2003. Chondroitin sulfate proteoglycans in the central nervous system: changes and synthesis after injury. Biochem. Soc. Trans. 31:335-36 (Pubitemid 36520669)
    • (2003) Biochemical Society Transactions , vol.31 , Issue.2 , pp. 335-336
    • Properzi, F.1    Asher, R.A.2    Fawcett, J.W.3
  • 101
    • 14044250276 scopus 로고    scopus 로고
    • Conditioning injury-induced spinal axon regeneration requires signal transducer and activator of transcription 3 activation
    • DOI 10.1523/JNEUROSCI.3269-04.2005
    • Qiu J, Cafferty WB, McMahon SB, Thompson SW. 2005. Conditioning injury-induced spinal axon regeneration requires signal transducer and activator of transcription 3 activation. J. Neurosci. 25:1645-53 (Pubitemid 40279269)
    • (2005) Journal of Neuroscience , vol.25 , Issue.7 , pp. 1645-1653
    • Qiu, J.1    Cafferty, W.B.J.2    McMahon, S.B.3    Thompson, S.W.N.4
  • 102
    • 0037071880 scopus 로고    scopus 로고
    • Spinal axon regeneration induced by elevation of cyclic AMP
    • DOI 10.1016/S0896-6273(02)00730-4
    • Qiu J, Cai D, Dai H, McAtee M, Hoffman PN, et al. 2002. Spinal axon regeneration induced by elevation of cyclic AMP. Neuron 34:895-903 (Pubitemid 34722280)
    • (2002) Neuron , vol.34 , Issue.6 , pp. 895-903
    • Qiu, J.1    Cai, D.2    Dai, H.3    McAtee, M.4    Hoffman, P.N.5    Bregman, B.S.6    Filbin, M.T.7
  • 104
    • 0033757632 scopus 로고    scopus 로고
    • Functional recovery of paraplegic rats and motor axon regeneration in their spinal cords by olfactory ensheathing glia
    • Ramon-Cueto A, Cordero MI, Santos-Benito FF, Avila J. 2000. Functional recovery of paraplegic rats and motor axon regeneration in their spinal cords by olfactory ensheathing glia. Neuron 25:425-35
    • (2000) Neuron , vol.25 , pp. 425-35
    • Ramon-Cueto, A.1    Cordero, M.I.2    Santos-Benito, F.F.3    Avila, J.4
  • 107
    • 0021220983 scopus 로고
    • Peripheral injury enhances central regeneration of primary sensory neurones
    • Richardson PM, Issa VM. 1984. Peripheral injury enhances central regeneration of primary sensory neurones. Nature 309:791-93 (Pubitemid 14119428)
    • (1984) Nature , vol.309 , Issue.5971 , pp. 791-793
    • Richardson, P.M.1    Issa, V.M.K.2
  • 110
    • 0022479004 scopus 로고
    • The induction of a regenerative propensity in sensory neurons following peripheral axonal injury
    • Richardson PM, Verge VM. 1986. The induction of a regenerative propensity in sensory neurons following peripheral axonal injury. J. Neurocytol. 15:585-94 (Pubitemid 16003707)
    • (1986) Journal of Neurocytology , vol.15 , Issue.5 , pp. 585-594
    • Richardson, P.M.1    Verge, V.M.K.2
  • 111
    • 77950860161 scopus 로고    scopus 로고
    • Retrograde signaling in axonal regeneration
    • Rishal I, Fainzilber M. 2010. Retrograde signaling in axonal regeneration. Exp. Neurol. 223:5-10
    • (2010) Exp. Neurol. , vol.223 , pp. 5-10
    • Rishal, I.1    Fainzilber, M.2
  • 112
    • 0029122188 scopus 로고
    • Differential regenerative response of Purkinje cell and inferior olivary axons confronted with embryonic grafts: Environmental cues versus intrinsic neuronal determinants
    • Rossi F, Jankovski A, Sotelo C. 1995. Differential regenerative response of Purkinje cell and inferior olivary axons confronted with embryonic grafts: environmental cues versus intrinsic neuronal determinants. J. Comp. Neurol. 359:663-77
    • (1995) J. Comp. Neurol. , vol.359 , pp. 663-77
    • Rossi, F.1    Jankovski, A.2    Sotelo, C.3
  • 114
    • 0015900146 scopus 로고
    • Effects of calcium ion concentration on the degeneration of amputated axons in tissue culture
    • Schlaepfer WW, Bunge RP. 1973. Effects of calcium ion concentration on the degeneration of amputated axons in tissue culture. J. Cell Biol. 59:456-70
    • (1973) J. Cell Biol. , vol.59 , pp. 456-70
    • Schlaepfer, W.W.1    Bunge, R.P.2
  • 115
    • 0028115777 scopus 로고
    • Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion
    • DOI 10.1038/367170a0
    • Schnell L, Schneider R, Kolbeck R, Barde YA, Schwab ME. 1994. Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion. Nature 367:170-73 (Pubitemid 24031697)
    • (1994) Nature , vol.367 , Issue.6459 , pp. 170-173
    • Schnell, L.1    Schneider, R.2    Kolbeck, R.3    Barde, Y.-A.4    Schwab, M.E.5
  • 116
    • 0019979195 scopus 로고
    • Growth and target finding by axons of the corticospinal tract in prenatal and postnatal rats
    • DOI 10.1016/0306-4522(82)90001-X
    • Schreyer DJ, Jones EG. 1982. Growth and target finding by axons of the corticospinal tract in prenatal and postnatal rats. Neuroscience 7:1837-53 (Pubitemid 12047329)
    • (1982) Neuroscience , vol.7 , Issue.8 , pp. 1837-1853
    • Schreyer, D.J.1    Jones, E.G.2
  • 117
    • 0029900303 scopus 로고    scopus 로고
    • Degeneration and regeneration of axons in the lesioned spinal cord
    • Schwab ME, Bartholdi D. 1996. Degeneration and regeneration of axons in the lesioned spinal cord. Physiol. Rev. 76:319-70 (Pubitemid 26163712)
    • (1996) Physiological Reviews , vol.76 , Issue.2 , pp. 319-370
    • Schwab, M.E.1    Bartholdi, D.2
  • 119
    • 0029925683 scopus 로고    scopus 로고
    • Intracellular signaling pathways activated by neurotrophic factors
    • Segal RA, Greenberg ME. 1996. Intracellular signaling pathways activated by neurotrophic factors. Annu. Rev. Neurosci. 19:463-89 (Pubitemid 26080836)
    • (1996) Annual Review of Neuroscience , vol.19 , pp. 463-489
    • Segal, R.A.1    Greenberg, M.E.2
  • 120
    • 0026694239 scopus 로고
    • Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration
    • Sendtner M, Stockli KA, Thoenen H. 1992. Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration. J. Cell Biol. 118:139-48
    • (1992) J. Cell Biol. , vol.118 , pp. 139-48
    • Sendtner, M.1    Stockli, K.A.2    Thoenen, H.3
  • 121
    • 0033151666 scopus 로고    scopus 로고
    • Retinal ganglion cells lose trophic responsiveness after axotomy
    • DOI 10.1016/S0896-6273(00)80780-1
    • Shen S, Wiemelt AP, McMorris FA, Barres BA. 1999. Retinal ganglion cells lose trophic responsiveness after axotomy. Neuron 23:285-95 (Pubitemid 29315724)
    • (1999) Neuron , vol.23 , Issue.2 , pp. 285-295
    • Shen, S.1    Wiemelt, A.P.2    McMorris, F.A.3    Barres, B.A.4
  • 122
    • 70350340041 scopus 로고    scopus 로고
    • Stretch growth of integrated axon tracts: Extremes and exploitations
    • Smith DH. 2009. Stretch growth of integrated axon tracts: extremes and exploitations. Prog. Neurobiol. 89:231-39
    • (2009) Prog. Neurobiol. , vol.89 , pp. 231-39
    • Smith, D.H.1
  • 123
    • 71149106854 scopus 로고    scopus 로고
    • SOCS3 deletion promotes optic nerve regeneration in vivo
    • Smith PD, Sun F, Park KK, Cai B, Wang C, et al. 2009. SOCS3 deletion promotes optic nerve regeneration in vivo. Neuron 64:617-23
    • (2009) Neuron , vol.64 , pp. 617-23
    • Smith, P.D.1    Sun, F.2    Park, K.K.3    Cai, B.4    Wang, C.5
  • 124
    • 0032483342 scopus 로고    scopus 로고
    • Conversion of neuronal growth cone responses from repulsion to attraction by cyclic nucleotides
    • DOI 10.1126/science.281.5382.1515
    • Song H, Ming G, He Z, Lehmann M, McKerracher L, et al. 1998. Conversion of neuronal growth cone responses from repulsion to attraction by cyclic nucleotides. Science 281:1515-18 (Pubitemid 28425577)
    • (1998) Science , vol.281 , Issue.5382 , pp. 1515-1518
    • Song, H.-J.1    Ming, G.-L.2    He, Z.3    Lehmann, M.4    McKerracher, L.5    Tessier-Lavigne, M.6    Poo, M.-M.7
  • 125
    • 0030877318 scopus 로고    scopus 로고
    • CAMP-induced switching in turning direction of nerve growth cones
    • Song HJ, Ming GL, Poo MM. 1997. cAMP-induced switching in turning direction of nerve growth cones. Nature 388:275-79
    • (1997) Nature , vol.388 , pp. 275-79
    • Song, H.J.1    Ming, G.L.2    Poo, M.M.3
  • 126
    • 24344470604 scopus 로고    scopus 로고
    • Chronic enhancement of the intrinsic growth capacity of sensory neurons combined with the degradation of inhibitory proteoglycans allows functional regeneration of sensory axons through the dorsal root entry zone in the mammalian spinal cord
    • DOI 10.1523/JNEUROSCI.2111-05.2005
    • Steinmetz MP, Horn KP, Tom VJ, Miller JH, Busch SA, et al. 2005. Chronic enhancement of the intrinsic growth capacity of sensory neurons combined with the degradation of inhibitory proteoglycans allows functional regeneration of sensory axons through the dorsal root entry zone in the mammalian spinal cord. J. Neurosci. 25:8066-76 (Pubitemid 41254410)
    • (2005) Journal of Neuroscience , vol.25 , Issue.35 , pp. 8066-8076
    • Steinmetz, M.P.1    Horn, K.P.2    Tom, V.J.3    Miller, J.H.4    Busch, S.A.5    Nair, D.6    Silver, D.J.7    Silver, J.8
  • 127
    • 0035844014 scopus 로고    scopus 로고
    • Synthesis of leukemia inhibitory factor in injured peripheral nerves and their cells
    • DOI 10.1016/S0006-8993(01)02323-X, PII S000689930102323X
    • Subang MC, Richardson PM. 2001. Synthesis of leukemia inhibitory factor in injured peripheral nerves and their cells. Brain Res. 900:329-31 (Pubitemid 32382129)
    • (2001) Brain Research , vol.900 , Issue.2 , pp. 329-331
    • Subang, M.C.1    Richardson, P.M.2
  • 128
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
    • Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, et al. 2007. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131:861-72 (Pubitemid 350138099)
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 129
    • 0029959555 scopus 로고    scopus 로고
    • The molecular biology of axon guidance
    • DOI 10.1126/science.274.5290.1123
    • Tessier-Lavigne M, Goodman CS. 1996. The molecular biology of axon guidance. Science 274:1123-33 (Pubitemid 26389268)
    • (1996) Science , vol.274 , Issue.5290 , pp. 1123-1133
    • Tessier-Lavigne, M.1    Goodman, C.S.2
  • 130
    • 16844378975 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β phosphorylation of MAP1B at Ser1260 and Thr1265 is spatially restricted to growing axons
    • DOI 10.1242/jcs.01697
    • Trivedi N, Marsh P, Goold RG, Wood-Kaczmar A, Gordon-Weeks PR. 2005. Glycogen synthase kinase-3beta phosphorylation of MAP1B at Ser1260 and Thr1265 is spatially restricted to growing axons. J. Cell Sci. 118:993-1005 (Pubitemid 40484889)
    • (2005) Journal of Cell Science , vol.118 , Issue.5 , pp. 993-1005
    • Trivedi, N.1    Marsh, P.2    Goold, R.G.3    Wood-Kaczmar, A.4    Gordon-Weeks, P.R.5
  • 131
    • 39249085066 scopus 로고    scopus 로고
    • Electrical stimulation of intact peripheral sensory axons in rats promotes outgrowth of their central projections
    • Udina E, Furey M, Busch S, Silver J, Gordon T, Fouad K. 2008. Electrical stimulation of intact peripheral sensory axons in rats promotes outgrowth of their central projections. Exp. Neurol. 210:238-47
    • (2008) Exp. Neurol. , vol.210 , pp. 238-47
    • Udina, E.1    Furey, M.2    Busch, S.3    Silver, J.4    Gordon, T.5    Fouad, K.6
  • 132
    • 34547652325 scopus 로고    scopus 로고
    • Why is Wallerian degeneration in the CNS so slow?
    • DOI 10.1146/annurev.neuro.30.051606.094354
    • Vargas ME, Barres BA. 2007. Why is Wallerian degeneration in the CNS so slow? Annu. Rev. Neurosci. 30:153-79 (Pubitemid 47218754)
    • (2007) Annual Review of Neuroscience , vol.30 , pp. 153-179
    • Vargas, M.E.1    Barres, B.A.2
  • 133
    • 77955349272 scopus 로고    scopus 로고
    • Endogenous antibodies promote rapid myelin clearance and effective axon regeneration after nerve injury
    • Vargas ME, Watanabe J, Singh SJ, Robinson WH, Barres BA. 2010. Endogenous antibodies promote rapid myelin clearance and effective axon regeneration after nerve injury. Proc. Natl. Acad. Sci. USA 107:11993-98
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 11993-98
    • Vargas, M.E.1    Watanabe, J.2    Singh, S.J.3    Robinson, W.H.4    Barres, B.A.5
  • 134
    • 36549068204 scopus 로고    scopus 로고
    • Gene expression analysis of zebrafish retinal ganglion cells during optic nerve regeneration identifies KLF6a and KLF7a as important regulators of axon regeneration
    • DOI 10.1016/j.ydbio.2007.09.019, PII S0012160607013735
    • Veldman MB, Bemben MA, Thompson RC, Goldman D. 2007. Gene expression analysis of zebrafish retinal ganglion cells during optic nerve regeneration identifies KLF6a and KLF7a as important regulators of axon regeneration. Dev. Biol. 312:596-612 (Pubitemid 350186315)
    • (2007) Developmental Biology , vol.312 , Issue.2 , pp. 596-612
    • Veldman, M.B.1    Bemben, M.A.2    Thompson, R.C.3    Goldman, D.4
  • 136
    • 0035909112 scopus 로고    scopus 로고
    • Judging a protein by more than its name: GSK-3
    • Woodgett JR. 2001. Judging a protein by more than its name: GSK-3. Sci. STKE 2001:re12
    • (2001) Sci. STKE , vol.2001
    • Woodgett, J.R.1
  • 137
    • 0020541745 scopus 로고
    • Correlation of axonal regeneration and slow component B in two branches of a single axon
    • Wujek JR, Lasek RJ. 1983. Correlation of axonal regeneration and slow component B in two branches of a single axon. J. Neurosci. 3:243-51 (Pubitemid 13125703)
    • (1983) Journal of Neuroscience , vol.3 , Issue.2 , pp. 243-251
    • Wujek, J.R.1    Lasek, R.J.2
  • 138
    • 69449105574 scopus 로고    scopus 로고
    • The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regeneration
    • Yan D, Wu Z, Chisholm AD, Jin Y. 2009. The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regeneration. Cell 138:1005-18
    • (2009) Cell , vol.138 , pp. 1005-18
    • Yan, D.1    Wu, Z.2    Chisholm, A.D.3    Jin, Y.4
  • 139
    • 16544363197 scopus 로고    scopus 로고
    • Functional regeneration after laser axotomy
    • DOI 10.1038/432822a
    • Yanik MF, Cinar H, Cinar HN, Chisholm AD, Jin Y, Ben-Yakar A. 2004. Neurosurgery: functional regeneration after laser axotomy. Nature 432:822 (Pubitemid 40037136)
    • (2004) Nature , vol.432 , Issue.7019 , pp. 822
    • Yanik, M.F.1    Cinar, H.2    Cinar, H.N.3    Chisholm, A.D.4    Jin, Y.5    Ben-Yakar, A.6
  • 140
    • 33745712928 scopus 로고    scopus 로고
    • Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells
    • Yin Y, Henzl MT, Lorber B, Nakazawa T, Thomas TT, et al. 2006. Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells. Nat. Neurosci. 9:843-52
    • (2006) Nat. Neurosci. , vol.9 , pp. 843-52
    • Yin, Y.1    Henzl, M.T.2    Lorber, B.3    Nakazawa, T.4    Thomas, T.T.5
  • 141
    • 33746308062 scopus 로고    scopus 로고
    • Glial inhibition of CNS axon regeneration
    • DOI 10.1038/nrn1956, PII NRN1956
    • Yiu G, He Z. 2006. Glial inhibition of CNS axon regeneration. Nat. Rev. Neurosci. 7:617-27 (Pubitemid 44106744)
    • (2006) Nature Reviews Neuroscience , vol.7 , Issue.8 , pp. 617-627
    • Yiu, G.1    He, Z.2
  • 142
    • 76249109093 scopus 로고    scopus 로고
    • Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish
    • Yoo SK, Deng Q, Cavnar PJ, Wu YI, Hahn KM, Huttenlocher A. 2010. Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish. Dev. Cell 18:226-36
    • (2010) Dev. Cell , vol.18 , pp. 226-36
    • Yoo, S.K.1    Deng, Q.2    Cavnar, P.J.3    Wu, Y.I.4    Hahn, K.M.5    Huttenlocher, A.6
  • 143
    • 0035514195 scopus 로고    scopus 로고
    • Dynamic regulation of axon guidance
    • Yu TW, Bargmann CI. 2001. Dynamic regulation of axon guidance. Nat. Neurosci. 4(Suppl.):1169-76 (Pubitemid 33733105)
    • (2001) Nature Neuroscience , vol.4 , Issue.SUPPL. 1 , pp. 1169-1176
    • Yu, T.W.1    Bargmann, C.I.2
  • 144
    • 0034610158 scopus 로고    scopus 로고
    • Positive injury signals induce growth and prolong survival in Aplysia neurons
    • Zhang XP, Ambron RT. 2000. Positive injury signals induce growth and prolong survival in Aplysia neurons. J. Neurobiol. 45:84-94
    • (2000) J. Neurobiol. , vol.45 , pp. 84-94
    • Zhang, X.P.1    Ambron, R.T.2
  • 146
    • 0033153020 scopus 로고    scopus 로고
    • Sensory impairments and delayed regeneration of sensory axons in interleukin-6-deficient mice
    • Zhong J, Dietzel ID, Wahle P, Kopf M, Heumann R. 1999. Sensory impairments and delayed regeneration of sensory axons in interleukin-6-deficient mice. J. Neurosci. 19:4305-13 (Pubitemid 29241084)
    • (1999) Journal of Neuroscience , vol.19 , Issue.11 , pp. 4305-4313
    • Zhong, J.1    Dietzel, I.D.2    Wahle, P.3    Kopf, M.4    Heumann, R.5
  • 147
    • 17644415297 scopus 로고    scopus 로고
    • GSK-3β and microtubule assembly in axons
    • DOI 10.1126/science.1110301
    • Zhou FQ, Snider WD. 2005. Cell biology: GSK-3beta and microtubule assembly in axons. Science 308:211-14 (Pubitemid 40558846)
    • (2005) Science , vol.308 , Issue.5719 , pp. 211-214
    • Zhou, F.-Q.1    Snider, W.D.2
  • 149
    • 2942735115 scopus 로고    scopus 로고
    • NGF-induced axon growth is mediated by localized inactivation of GSK-3β and functions of the microtubule plus end binding protein APC
    • DOI 10.1016/j.neuron.2004.05.011, PII S0896627304002958
    • Zhou FQ, Zhou J, Dedhar S, Wu YH, Snider WD. 2004. NGF-induced axon growth is mediated by localized inactivation of GSK-3beta and functions of the microtubule plus end binding protein APC. Neuron 42:897-912 (Pubitemid 38798229)
    • (2004) Neuron , vol.42 , Issue.6 , pp. 897-912
    • Zhou, F.-Q.1    Zhou, J.2    Dedhar, S.3    Wu, Y.-H.4    Snider, W.D.5
  • 150
    • 23044515099 scopus 로고    scopus 로고
    • Functions and mechanisms of retrograde neurotrophin signalling
    • DOI 10.1038/nrn1727
    • Zweifel LS, Kuruvilla R, Ginty DD. 2005. Functions and mechanisms of retrograde neurotrophin signalling. Nat. Rev. Neurosci. 6:615-25 (Pubitemid 41059336)
    • (2005) Nature Reviews Neuroscience , vol.6 , Issue.8 , pp. 615-625
    • Zweifel, L.S.1    Kuruvilla, R.2    Ginty, D.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.