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Volumn 9, Issue 5, 2012, Pages 274-282

The role of connexins in prostate cancer promotion and progression

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 26; CONNEXIN 32; CONNEXIN 43; DOCETAXEL; GAP JUNCTION PROTEIN;

EID: 84862156068     PISSN: 17594812     EISSN: 17594820     Source Type: Journal    
DOI: 10.1038/nrurol.2012.14     Document Type: Review
Times cited : (64)

References (127)
  • 1
    • 42149122683 scopus 로고    scopus 로고
    • Prostatic preneoplasia and beyond
    • Joshua, A. M. et al. Prostatic preneoplasia and beyond. Biochim. Biophys. Acta 1785, 156-181 (2008
    • (2008) Biochim. Biophys. Acta. , vol.1785 , pp. 156-181
    • Joshua, A.M.1
  • 2
    • 63249118690 scopus 로고    scopus 로고
    • Screening and prostate-cancer mortality in a randomized European study
    • Schröder, F. H. et al. Screening and prostate-cancer mortality in a randomized European study. N. Engl. J. Med. 360, 1320-1328 (2009
    • (2009) N. Engl. J. Med. , vol.360 , pp. 1320-1328
    • Schröder, F.H.1
  • 3
    • 80051580618 scopus 로고    scopus 로고
    • Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
    • Siegel, R., Ward, E., Brawley, O. & Jemal, A. Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J. Clin. 61, 212-236 (2011
    • (2011) CA Cancer J. Clin. , vol.61 , pp. 212-236
    • Siegel, R.1    Ward, E.2    Brawley, O.3    Jemal, A.4
  • 4
    • 77953210095 scopus 로고    scopus 로고
    • On the stem cell origin of cancer
    • Sell, S. On the stem cell origin of cancer. Am. J. Pathol. 176, 2584-2594 (2010
    • (2010) Am. J. Pathol. , vol.176 , pp. 2584-2594
    • Sell, S.1
  • 5
    • 75149132546 scopus 로고    scopus 로고
    • Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity
    • Sottoriva, A. et al. Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity. Cancer Res. 70, 46-56 (2010
    • (2010) Cancer Res. , vol.70 , pp. 46-56
    • Sottoriva, A.1
  • 7
    • 28544449786 scopus 로고    scopus 로고
    • A tumour stem cell hypothesis for the origins of prostate cancer
    • Maitland, N. J. & Collins, A. A tumour stem cell hypothesis for the origins of prostate cancer. BJU Int. 96, 1219-1223 (2005
    • (2005) BJU Int. , vol.96 , pp. 1219-1223
    • Maitland, N.J.1    Collins, A.2
  • 8
    • 0030021453 scopus 로고    scopus 로고
    • Differentiation pathways and histogenetic aspects of normal and abnormal prostatic growth: A stem cell model
    • Bonkhoff, H. & Remberger, K. Differentiation pathways and histogenetic aspects of normal and abnormal prostatic growth: a stem cell model. Prostate 28, 98-106 (1996
    • (1996) Prostate , vol.28 , pp. 98-106
    • Bonkhoff, H.1    Remberger, K.2
  • 9
    • 0029819186 scopus 로고    scopus 로고
    • Role of the basal cells in premalignant changes of the human prostate: A stem cell concept for the development of prostate cancer
    • Bonkhoff, H. Role of the basal cells in premalignant changes of the human prostate: a stem cell concept for the development of prostate cancer. Eur. Urol. 30, 201-205 (1996
    • (1996) Eur. Urol. , vol.30 , pp. 201-205
    • Bonkhoff, H.1
  • 10
    • 77955121375 scopus 로고    scopus 로고
    • Identification of a cell of origin for human prostate cancer
    • Goldstein, A. S., Huang, J., Guo, C., Garraway, I. P. & Witte, O. N. Identification of a cell of origin for human prostate cancer. Science 329, 568-571 (2010
    • (2010) Science , vol.329 , pp. 568-571
    • Goldstein, A.S.1    Huang, J.2    Guo, C.3    Garraway, I.P.4    Witte, O.N.5
  • 11
    • 80051703400 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition in prostate cancer: Paradigm or puzzle
    • Nauseef, J. T. & Henry, M. D. Epithelial-to-mesenchymal transition in prostate cancer: paradigm or puzzle? Nat. Rev. Urol. 8, 428-439 (2011
    • (2011) Nat. Rev. Urol. , vol.8 , pp. 428-439
    • Nauseef, J.T.1    Henry, M.D.2
  • 12
    • 33645469482 scopus 로고    scopus 로고
    • Stem cells and their niches
    • Moore, K. A. & Lemischka, I. R. Stem cells and their niches. Science 311, 1880-1885 (2006
    • (2006) Science , vol.311 , pp. 1880-1885
    • Moore, K.A.1    Lemischka, I.R.2
  • 13
    • 75349083520 scopus 로고    scopus 로고
    • Stem cells and the niche: A dynamic duo
    • Voog, J. & Jones, D. L. Stem cells and the niche: a dynamic duo. Cell Stem Cell 6, 103-115 (2010
    • (2010) Cell Stem Cell , vol.6 , pp. 103-115
    • Voog, J.1    Jones, D.L.2
  • 14
    • 34548235468 scopus 로고    scopus 로고
    • New experimental markers for early detection of high-Risk prostate cancer: Role of cell-cell adhesion and cell migration
    • Mol, A. J., Geldof, A. A., Meijer, G. A., van der Poel, H. G. & van Moorselaar, R. J. New experimental markers for early detection of high-risk prostate cancer: role of cell-cell adhesion and cell migration. J. Cancer Res. Clin. Oncol. 133, 687-695 (2007
    • (2007) J. Cancer Res. Clin. Oncol. , vol.133 , pp. 687-695
    • Mol, A.J.1    Geldof, A.A.2    Meijer, G.A.3    Van Der Poel, H.G.4    Van Moorselaar, R.J.5
  • 15
    • 8444245596 scopus 로고    scopus 로고
    • Connexins and cell signaling in development and disease
    • Wei, C. J., Xu, X. & Lo, C. W. Connexins and cell signaling in development and disease. Annu. Rev. Cell Dev. Biol. 20, 811-838 (2004
    • (2004) Annu. Rev. Cell Dev. Biol. , vol.20 , pp. 811-838
    • Wei, C.J.1    Xu, X.2    Lo, C.W.3
  • 16
    • 36249015391 scopus 로고    scopus 로고
    • Gap junctional intercellular communication as a biological Rosetta stone in understanding in a systems biological manner stem cell behavior mechanisms of epigenetic toxicology chemoprevention and chemotherapy
    • Trosko, J. E. Gap junctional intercellular communication as a biological "Rosetta stone" in understanding, in a systems biological manner, stem cell behavior, mechanisms of epigenetic toxicology, chemoprevention and chemotherapy. J. Membr. Biol. 218, 93-100 (2007
    • (2007) J. Membr. Biol. , vol.218 , pp. 93-100
    • Trosko, J.E.1
  • 17
    • 0018382741 scopus 로고
    • Junctional intercellular communication and the control of growth
    • Loewenstein, W. R. Junctional intercellular communication and the control of growth. Biochim. Biophys. Acta 560, 1-65 (1979
    • (1979) Biochim. Biophys. Acta. , vol.560 , pp. 1-65
    • Loewenstein, W.R.1
  • 18
    • 0037292354 scopus 로고    scopus 로고
    • Disruption of gap junctions in toxicity and carcinogenicity
    • Chipman, J. K., Mally, A. & Edwards, G. O. Disruption of gap junctions in toxicity and carcinogenicity. Toxicol. Sci. 71, 146-153 (2003
    • (2003) Toxicol. Sci. , vol.71 , pp. 146-153
    • Chipman, J.K.1    Mally, A.2    Edwards, G.O.3
  • 20
    • 43549124558 scopus 로고    scopus 로고
    • The stage-specific function of gap junctions during tumourigenesis
    • Czyz, J. The stage-specific function of gap junctions during tumourigenesis. Cell. Mol. Biol. Lett. 13, 92-102 (2008
    • (2008) Cell. Mol. Biol. Lett. , vol.13 , pp. 92-102
    • Czyz, J.1
  • 22
    • 69949090953 scopus 로고    scopus 로고
    • Connexins: A myriad of functions extending beyond assembly of gap junction channels
    • Dbouk, H. A., Mroue, R. M., El-Sabban, M. E. & Talhouk, R. S. Connexins: a myriad of functions extending beyond assembly of gap junction channels. Cell Commun. Signal. 7, 4 (2009
    • (2009) Cell Commun. Signal. , vol.7 , pp. 4
    • Dbouk, H.A.1    Mroue, R.M.2    El-Sabban, M.E.3    Talhouk, R.S.4
  • 24
    • 0032894558 scopus 로고    scopus 로고
    • Impaired expression and posttranslational processing of connexin43 and downregulation of gap junctional communication in neoplastic human prostate cells
    • Hossain, M. Z. et al. Impaired expression and posttranslational processing of connexin43 and downregulation of gap junctional communication in neoplastic human prostate cells. Prostate 38, 55.59 (1999
    • (1999) Prostate , vol.38 , pp. 55-59
    • Hossain, M.Z.1
  • 25
    • 0036141985 scopus 로고    scopus 로고
    • Alterations in gap junction protein expression in human benign prostatic hyperplasia and prostate cancer
    • Habermann, H., Ray, V., Habermann, W. & Prins, G. S. Alterations in gap junction protein expression in human benign prostatic hyperplasia and prostate cancer. J. Urol. 167, 655.660 (2002
    • (2002) J. Urol. , vol.167 , pp. 655-660
    • Habermann, H.1    Ray, V.2    Habermann, W.3    Prins, G.S.4
  • 26
    • 29244438457 scopus 로고    scopus 로고
    • Contact stimulation of prostate cancer cell migration: The role of gap junctional coupling and migration stimulated by heterotypic cell-to-cell contacts in determination of the metastatic phenotype of Dunning rat prostate cancer cells
    • Miekus, K., Czernik, M., Sroka, J., Czyz., J. & Madeja, Z. Contact stimulation of prostate cancer cell migration: the role of gap junctional coupling and migration stimulated by heterotypic cell-to-cell contacts in determination of the metastatic phenotype of Dunning rat prostate cancer cells. Biol. Cell 97, 893.903 (2005
    • (2005) Biol. Cell , vol.97 , pp. 893-903
    • Miekus, K.1    Czernik, M.2    Sroka, J.3    Czyz, J.4    Madeja, Z.5
  • 27
    • 29344472071 scopus 로고    scopus 로고
    • Changes in gap junctional connexin isoforms during prostate cancer progression
    • Tate, A. W. et al. Changes in gap junctional connexin isoforms during prostate cancer progression. Prostate 66, 19.31 (2006
    • (2006) Prostate , vol.66 , pp. 19-31
    • Tate, A.W.1
  • 28
    • 69249098949 scopus 로고    scopus 로고
    • Cell cell nanotubes: Tunneling through several types of synapses
    • Tarakanov, A. O. & Goncharova, L. B. Cell.cell nanotubes: Tunneling through several types of synapses. Commun. Integr. Biol. 2, 359.361 (2009
    • (2009) Commun. Integr. Biol. , Issue.2 , pp. 359-361
    • Tarakanov, A.O.1    Goncharova, L.B.2
  • 29
    • 79953690482 scopus 로고    scopus 로고
    • Structure of the gap junction channel and its implications for its biological functions
    • Maeda, S. & Tsukihara, T. Structure of the gap junction channel and its implications for its biological functions. Cell. Mol. Life Sci. 68, 1115.1129 (2011
    • (2011) Cell. Mol. Life Sci. , vol.68 , pp. 1115-1129
    • Maeda, S.1    Tsukihara, T.2
  • 30
    • 0035991948 scopus 로고    scopus 로고
    • Gap junctions: Structure and function (review)
    • Evans, W. H. & Martin, P. E. Gap junctions: structure and function (review). Mol. Membr. Biol. 19, 121.136 (2002
    • (2002) Mol. Membr. Biol. , vol.19 , pp. 121-136
    • Evans, W.H.1    Martin, P.E.2
  • 31
    • 79958051592 scopus 로고    scopus 로고
    • Regulation of cellular function by connexin hemichannels
    • Burra, S. & Jiang, J. X. Regulation of cellular function by connexin hemichannels. Int. J. Biochem. Mol. Biol. 2, 119.128 (2011
    • (2011) Int. J. Biochem. Mol. Biol. , Issue.2 , pp. 119-128
    • Burra, S.1    Jiang, J.X.2
  • 32
    • 77956376324 scopus 로고    scopus 로고
    • Dendritic processes of osteocytes are mechanotransducers that induce the opening of hemichannels
    • Burra, S. et al. Dendritic processes of osteocytes are mechanotransducers that induce the opening of hemichannels. Proc. Natl Acad. Sci. USA 107, 13648.13653 (2010
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 13648-13653
    • Burra, S.1
  • 33
    • 60149097598 scopus 로고    scopus 로고
    • Adhesive properties of connexin hemichannels
    • Cotrina, M. L., Lin, J. H. & Nedergaard, M. Adhesive properties of connexin hemichannels. Glia 56, 1791.1798 (2008
    • (2008) Glia , vol.56 , pp. 1791-1798
    • Cotrina, M.L.1    Lin, J.H.2    Nedergaard, M.3
  • 34
    • 0037184068 scopus 로고    scopus 로고
    • Gap junctions between cells expressing connexin 43 or 32 show inverse permselectivity to adenosine and ATP
    • Goldberg, G. S., Moreno, A. P. & Lampe, P. D. Gap junctions between cells expressing connexin 43 or 32 show inverse permselectivity to adenosine and ATP. J. Biol. Chem. 277, 36725.36730 (2002
    • (2002) J. Biol. Chem. , Issue.277 , pp. 36725-36730
    • Goldberg, G.S.1    Moreno, A.P.2    Lampe, P.D.3
  • 35
    • 33744480573 scopus 로고    scopus 로고
    • Life cycle of connexins: Regulation of connexin synthesis and degradation
    • Salameh, A. Life cycle of connexins: regulation of connexin synthesis and degradation. Adv. Cardiol. 42, 57.70 (2006
    • (2006) Adv. Cardiol. , vol.42 , pp. 57-70
    • Salameh, A.1
  • 36
    • 1642385314 scopus 로고    scopus 로고
    • Chemical gating of gap junction channels; roles of calcium, pH and calmodulin
    • Peracchia, C. Chemical gating of gap junction channels; roles of calcium, pH and calmodulin. Biochim. Biophys. Acta 1662, 61.80 (2004
    • (2004) Biochim. Biophys. Acta , vol.1662 , pp. 61-80
    • Peracchia, C.1
  • 37
    • 33645002735 scopus 로고    scopus 로고
    • Life cycle of connexins in health and disease
    • Laird, D. W. Life cycle of connexins in health and disease. Biochem. J. 394, 527.543 (2006
    • (2006) Biochem.J. , vol.394 , pp. 527-543
    • Laird, D.W.1
  • 38
    • 64249170988 scopus 로고    scopus 로고
    • Connexin43 phosphorylation: Structural changes and biological effects
    • Solan, J. L. & Lampe, P. D. Connexin43 phosphorylation: structural changes and biological effects. Biochem. J. 419, 261.272 (2009
    • (2009) Biochem.J. , Issue.419 , pp. 261-272
    • Solan, J.L.1    Lampe, P.D.2
  • 39
    • 0035833252 scopus 로고    scopus 로고
    • Modulation of mouse neural crest cell motility by N-Cadherin and connexin 43 gap junctions
    • Xu, X. et al. Modulation of mouse neural crest cell motility by N-cadherin and connexin 43 gap junctions. J. Cell Biol. 154, 217.230 (2001
    • (2001) J. Cell Biol. , vol.154 , pp. 217-230
    • Xu, X.1
  • 40
    • 54149110523 scopus 로고    scopus 로고
    • Heterocellular interaction enhances recruitment of α and β -catenins and ZO-2 into functional gap-junction complexes and induces gap junction-Dependent differentiation of mammary epithelial cells
    • Talhouk, R. S. et al. Heterocellular interaction enhances recruitment of α¿ and Á-catenins and ZO-2 into functional gap-junction complexes and induces gap junction-dependent differentiation of mammary epithelial cells. Exp. Cell Res. 314, 3275.3291 (2008
    • (2008) Exp. Cell Res. , vol.314 , pp. 3275-3291
    • Talhouk, R.S.1
  • 41
    • 80054690365 scopus 로고    scopus 로고
    • Connexin43 modulates cell polarity and directional cell migration by regulating microtubule dynamics
    • Francis, R. et al. Connexin43 modulates cell polarity and directional cell migration by regulating microtubule dynamics. PLoS ONE 6, e26379 (2011
    • (2011) PLoS ONE , vol.6
    • Francis, R.1
  • 42
    • 34548186903 scopus 로고    scopus 로고
    • Gap junction adhesion is necessary for radial migration in the neocortex
    • Elias, L. A., Wang, D. D. & Kriegstein, A. R. Gap junction adhesion is necessary for radial migration in the neocortex. Nature 448, 901.907 (2007
    • (2007) Nature , vol.448 , pp. 901-907
    • Elias, L.A.1    Wang, D.D.2    Kriegstein, A.R.3
  • 43
    • 60849097265 scopus 로고    scopus 로고
    • Involvement of the cytoplasmic C-Terminal domain of connexin43 in neuronal migration
    • Cina, C. et al. Involvement of the cytoplasmic C-terminal domain of connexin43 in neuronal migration. J. Neurosci. 29, 2009.2021 (2009
    • (2009) J. Neurosci. , vol.29 , pp. 2009-2021
    • Cina, C.1
  • 44
    • 0037379773 scopus 로고    scopus 로고
    • A novel route for connexin 43 to inhibit cell proliferation: Negative regulation of S-phase kinase-associated protein (Skp 2)
    • Zhang, Y. W., Nakayama, K., Nakayama, K. & Morita, I. A novel route for connexin 43 to inhibit cell proliferation: negative regulation of S-phase kinase-associated protein (Skp 2). Cancer Res. 63, 1623.1630 (2003
    • (2003) Cancer Res. , Issue.63 , pp. 1623-1630
    • Zhang, Y.W.1    Nakayama, K.2    Nakayama, K.3    Morita, I.4
  • 45
    • 34249110604 scopus 로고    scopus 로고
    • The role of connexins in controlling cell growth and gene expression
    • Kardami, E. et al. The role of connexins in controlling cell growth and gene expression. Prog. Biophys. Mol. Biol. 94, 245.264 (2007
    • (2007) Prog. Biophys. Mol. Biol. , vol.94 , pp. 245-264
    • Kardami, E.1
  • 46
    • 0037281030 scopus 로고    scopus 로고
    • The carboxy-Tail of connexin-43 localizes to the nucleus and inhibits cell growth
    • Dang, X., Doble, B. W. & Kardami, E. The carboxy-tail of connexin-43 localizes to the nucleus and inhibits cell growth. Mol. Cell Biochem. 242, 35.38 (2003
    • (2003) Mol. Cell Biochem. , vol.242 , pp. 35-38
    • Dang, X.1    Doble, B.W.2    Kardami, E.3
  • 47
    • 80052260149 scopus 로고    scopus 로고
    • Epigenetics in prostate cancer: Biologic and clinical relevance
    • Jeronimo, C. et al. Epigenetics in prostate cancer: biologic and clinical relevance. Eur. Urol. 60, 753.766 (2011
    • (2011) Eur. Urol. , vol.60 , pp. 753-766
    • Jeronimo, C.1
  • 48
    • 77952929243 scopus 로고    scopus 로고
    • Implications and challenges of connexin connections to cancer
    • Naus, C. C. & Laird, D. W. Implications and challenges of connexin connections to cancer. Nat. Rev. Cancer 10, 435.441 (2010
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 435-441
    • Naus, C.C.1    Laird, D.W.2
  • 50
    • 0025972397 scopus 로고
    • Transfection of C6 glioma cells with connexin 43 cDNA: Analysis of expression, intercellular coupling, and cell proliferation
    • Zhu, D., Caveney, S., Kidder, G. M. & Naus, C. C. Transfection of C6 glioma cells with connexin 43 cDNA: analysis of expression, intercellular coupling, and cell proliferation. Proc. Natl Acad. Sci. USA 88, 1883.1887 (1991
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 1883-1887
    • Zhu, D.1    Caveney, S.2    Kidder, G.M.3    Naus, C.C.4
  • 51
    • 0029015909 scopus 로고
    • Connexin43 reverses the phenotype of transformed cells and alters their expression of cyclin/cyclin-Dependent kinases
    • Chen, S. C., Pelletier, D. B., Ao, P. & Boynton, A. L. Connexin43 reverses the phenotype of transformed cells and alters their expression of cyclin/cyclin-dependent kinases. Cell Growth Differ. 6, 681.690 (1995
    • (1995) Cell Growth Differ. , Issue.6 , pp. 681-690
    • Chen, S.C.1    Pelletier, D.B.2    Ao, P.3    Boynton, A.L.4
  • 52
    • 0034326248 scopus 로고    scopus 로고
    • Connexin43 suppresses MFG-E8 while inducing contact growth inhibition of glioma cells
    • Goldberg, G. S. et al. Connexin43 suppresses MFG-E8 while inducing contact growth inhibition of glioma cells. Cancer Res. 60, 6018.6026 (2000
    • (2000) Cancer Res. , vol.60 , pp. 6018-6026
    • Goldberg, G.S.1
  • 53
    • 3142676384 scopus 로고    scopus 로고
    • Negative growth control of renal cell carcinoma cell by connexin 32: Possible involvement of Her-2
    • Fujimoto, E. et al. Negative growth control of renal cell carcinoma cell by connexin 32: possible involvement of Her-2. Mol. Carcinog. 40, 135.142 (2004
    • (2004) Mol. Carcinog. , vol.40 , pp. 135-142
    • Fujimoto, E.1
  • 54
    • 0032967790 scopus 로고    scopus 로고
    • Suppression of human prostate cancer cell growth by forced expression of connexin genes
    • Mehta, P. P. et al. Suppression of human prostate cancer cell growth by forced expression of connexin genes. Dev. Genet. 24, 91.110 (1999
    • (1999) Dev. Genet. , vol.24 , pp. 91-110
    • Mehta, P.P.1
  • 55
    • 0029827827 scopus 로고    scopus 로고
    • Gap junction genes Cx26 and Cx43 individually suppress the cancer phenotype of human mammary carcinoma cells and restore differentiation potential
    • Hirschi, K. K., Xu, C. E., Tsukamoto, T. & Sager, R. Gap junction genes Cx26 and Cx43 individually suppress the cancer phenotype of human mammary carcinoma cells and restore differentiation potential. Cell Growth Differ. 7, 861.870 (1996
    • (1996) Cell Growth Differ. , vol.7 , pp. 861-870
    • Hirschi, K.K.1    Xu, C.E.2    Tsukamoto, T.3    Sager, R.4
  • 56
    • 36249001676 scopus 로고    scopus 로고
    • Connexins and gap junctions in mammary gland development and breast cancer progression
    • McLachlan, E., Shao, Q. & Laird, D. W. Connexins and gap junctions in mammary gland development and breast cancer progression. J. Membr. Biol. 218, 107.121 (2007
    • (2007) J. Membr. Biol. , Issue.218 , pp. 107-121
    • McLachlan, E.1    Shao, Q.2    Laird, D.W.3
  • 57
    • 14944382346 scopus 로고    scopus 로고
    • Ignored hallmarks of carcinogenesis: Stem cells and cell-cell communication
    • Trosko, J. E., Chang, C. C., Upham, B. L. & Tai, M. H. Ignored hallmarks of carcinogenesis: stem cells and cell-cell communication. Ann. NY Acad. Sci. 1028, 192.201 (2004
    • (2004) Ann. NY Acad. Sci. , Issue.1028 , pp. 192-201
    • Trosko, J.E.1    Chang, C.C.2    Upham, B.L.3    Tai, M.H.4
  • 58
    • 0344541959 scopus 로고    scopus 로고
    • Connexin transfection induces invasive properties in HeLa cells
    • Graeber, S. H. & Hulser, D. F. Connexin transfection induces invasive properties in HeLa cells. Exp. Cell Res. 243, 142.149 (1998
    • (1998) Exp. Cell Res. , Issue.243 , pp. 142-149
    • Graeber, S.H.1    Hulser, D.F.2
  • 59
    • 12944281757 scopus 로고    scopus 로고
    • A role for heterologous gap junctions between melanoma and endothelial cells in metastasis
    • Ito, A. et al. A role for heterologous gap junctions between melanoma and endothelial cells in metastasis. J. Clin. Invest. 105, 1189.1197 (2000
    • (2000) J. Clin. Invest. , vol.105 , pp. 1189-1197
    • Ito, A.1
  • 60
    • 0036618222 scopus 로고    scopus 로고
    • Connexin 43 enhances the adhesivity and mediates the invasion of malignant glioma cells
    • Lin, J. H. et al. Connexin 43 enhances the adhesivity and mediates the invasion of malignant glioma cells. J. Neurosci. 22, 4302.4311 (2002
    • (2002) J. Neurosci. , vol.22 , pp. 4302-4311
    • Lin, J.H.1
  • 61
    • 35048878752 scopus 로고    scopus 로고
    • Connexin43 enhances glioma invasion by a mechanism involving the carboxy terminus
    • Bates, D. C., Sin, W. C., Aftab, Q. & Naus, C. C. Connexin43 enhances glioma invasion by a mechanism involving the carboxy terminus. Glia 55, 1554.1564 (2007
    • (2007) Glia , vol.55 , pp. 1554-1564
    • Bates, D.C.1    Sin, W.C.2    Aftab, Q.3    Naus, C.C.4
  • 62
    • 33644991492 scopus 로고    scopus 로고
    • Increased expression of connexin 26 in the invasive component of lung squamous cell carcinoma: Significant correlation with poor prognosis
    • Ito, A. et al. Increased expression of connexin 26 in the invasive component of lung squamous cell carcinoma: significant correlation with poor prognosis. Cancer Lett. 234, 239.248 (2006
    • (2006) Cancer Lett. , vol.234 , pp. 239-248
    • Ito, A.1
  • 63
    • 33645695606 scopus 로고    scopus 로고
    • Increased expression of connexins 26 and 43 in lymph node metastases of breast cancer
    • Kanczuga-Koda, L. et al. Increased expression of connexins 26 and 43 in lymph node metastases of breast cancer. J. Clin. Pathol. 59, 429.433 (2006
    • (2006) J. Clin. Pathol. , vol.59 , pp. 429-433
    • Kanczuga-Koda, L.1
  • 64
    • 79958190252 scopus 로고    scopus 로고
    • Visualization of connexin 43-Positive cells of glioma and the periglioma zone by means of intravenously injected monoclonal antibodies
    • Baklaushev, V. P. et al. Visualization of connexin 43-positive cells of glioma and the periglioma zone by means of intravenously injected monoclonal antibodies. Drug Deliv. 18, 331.337 (2011
    • (2011) Drug Deliv. , vol.18 , pp. 331-337
    • Baklaushev, V.P.1
  • 65
    • 80052675348 scopus 로고    scopus 로고
    • Connexin43 expression increases in the epithelium and stroma along the colonic neoplastic progression pathway: Implications for its oncogenic role
    • Han, Y. et al. Connexin43 expression increases in the epithelium and stroma along the colonic neoplastic progression pathway: implications for its oncogenic role. Gastroenterol. Res. Pract. 2011, 561719 (2011
    • (2011) Gastroenterol. Res. Pract. , vol.2011 , pp. 561719
    • Han, Y.1
  • 66
    • 79960338701 scopus 로고    scopus 로고
    • Expression and significance of Cx43 and E-cadherin in gastric cancer and metastatic lymph nodes
    • Tang, B., Peng, Z. H., Yu, P. W., Yu, G. & Qian, F. Expression and significance of Cx43 and E-cadherin in gastric cancer and metastatic lymph nodes. Med. Oncol. 28, 502.508 (2011
    • (2011) Med. Oncol. , vol.28 , pp. 502-508
    • Tang, B.1    Peng, Z.H.2    Yu, P.W.3    Yu, G.4    Qian, F.5
  • 67
    • 34848858289 scopus 로고    scopus 로고
    • Connexin26 expression is associated with lymphatic vessel invasion and poor prognosis in human breast cancer
    • Naoi, Y. et al. Connexin26 expression is associated with lymphatic vessel invasion and poor prognosis in human breast cancer. Breast Cancer Res. Treat. 106, 11.17 (2007
    • (2007) Breast Cancer Res. Treat. , vol.106 , pp. 11-17
    • Naoi, Y.1
  • 68
    • 0031936139 scopus 로고    scopus 로고
    • Endothelial cell intracellular Ca2+ concentration is increased upon breast tumor cell contact and mediates tumor cell transendothelial migration
    • Lewalle, J. M., Cataldo, D., Bajou, K., Lambert, C. A. & Foidart, J. M. Endothelial cell intracellular Ca2+ concentration is increased upon breast tumor cell contact and mediates tumor cell transendothelial migration. Clin. Exp. Metastasis 16, 21-29 (1998
    • (1998) Clin. Exp. Metastasis , vol.16 , pp. 21-29
    • Lewalle, J.M.1    Cataldo, D.2    Bajou, K.3    Lambert, C.A.4    Foidart, J.M.5
  • 69
    • 48649102225 scopus 로고    scopus 로고
    • Connexin-43 upregulation in micrometastases and tumor vasculature and its role in tumor cell attachment to pulmonary endothelium
    • Elzarrad, M. K. et al. Connexin-43 upregulation in micrometastases and tumor vasculature and its role in tumor cell attachment to pulmonary endothelium. BMC Med. 6, 20 (2008
    • (2008) BMC Med. , vol.6 , pp. 20
    • Elzarrad, M.K.1
  • 70
    • 26844503858 scopus 로고    scopus 로고
    • Connexin 43 mediated gap junctional communication enhances breast tumor cell diapedesis in culture
    • Pollmann, M..A., Shao, Q., Laird, D. W. & Sandig, M. Connexin 43 mediated gap junctional communication enhances breast tumor cell diapedesis in culture. Breast Cancer Res. 7, R522.R534 (2005
    • (2005) Breast Cancer Res. , vol.7
    • Pollmann, M.A.1    Shao, Q.2    Laird, D.W.3    Sandig, M.4
  • 71
    • 34250857019 scopus 로고    scopus 로고
    • Tumor cell-Organ microenvironment interactions in the pathogenesis of cancer metastasis
    • Langley, R. R. & Fidler, I. J. Tumor cell-organ microenvironment interactions in the pathogenesis of cancer metastasis. Endocr. Rev. 28, 297.321 (2007
    • (2007) Endocr. Rev. , vol.28 , pp. 297-321
    • Langley, R.R.1    Fidler, I.J.2
  • 72
    • 33749432911 scopus 로고    scopus 로고
    • Connexin 32 as an anti-invasive and anti-metastatic gene in renal cell carcinoma
    • Yano, T. et al. Connexin 32 as an anti-invasive and anti-metastatic gene in renal cell carcinoma. Biol. Pharm. Bull. 29, 1991.1994 (2006
    • (2006) Biol. Pharm. Bull. , vol.29 , pp. 1991-1994
    • Yano, T.1
  • 73
    • 44949185610 scopus 로고    scopus 로고
    • The inhibitory effect of connexin 32 gene on metastasis in renal cell carcinoma
    • Sato, H. et al. The inhibitory effect of connexin 32 gene on metastasis in renal cell carcinoma. Mol. Carcinog. 47, 403.409 (2008
    • (2008) Mol. Carcinog. , vol.47 , pp. 403-409
    • Sato, H.1
  • 74
    • 57049158673 scopus 로고    scopus 로고
    • Expressing connexin 43 in breast cancer cells reduces their metastasis to lungs
    • Li, Z., Zhou, Z., Welch, D. R. & Donahue, H. J. Expressing connexin 43 in breast cancer cells reduces their metastasis to lungs. Clin. Exp. Metastasis 25, 893.901 (2008
    • (2008) Clin. Exp. Metastasis , vol.25 , pp. 893-901
    • Li, Z.1    Zhou, Z.2    Welch, D.R.3    Donahue, H.J.4
  • 75
    • 58949102562 scopus 로고    scopus 로고
    • Connexin 43 recruits E-cadherin expression and inhibits the malignant behaviour of lung cancer cells
    • Xu, H. T. et al. Connexin 43 recruits E-cadherin expression and inhibits the malignant behaviour of lung cancer cells. Folia Histochem. Cytobiol. 46, 315.321 (2008
    • (2008) Folia Histochem. Cytobiol. , vol.46 , pp. 315-321
    • Xu, H.T.1
  • 76
    • 79951773787 scopus 로고    scopus 로고
    • Clinical significance of vascular endothelial growth factor and connexin43 for predicting pancreatic cancer clinicopathologic parameters
    • Liang, Q. L., Wang, B. R., Chen, G. Q., Li, G. H. & Xu, Y. Y. Clinical significance of vascular endothelial growth factor and connexin43 for predicting pancreatic cancer clinicopathologic parameters. Med. Oncol. 27, 1164.1170 (2010
    • (2010) Med. Oncol. , vol.27 , pp. 1164-1170
    • Liang, Q.L.1    Wang, B.R.2    Chen, G.Q.3    Li, G.H.4    Xu, Y.Y.5
  • 77
    • 0043233156 scopus 로고    scopus 로고
    • Interstitial cells in the human prostate: A new therapeutic target
    • Van der Aa, F., Roskams, T., Blyweert, W. & De Ridder, D. Interstitial cells in the human prostate: a new therapeutic target? Prostate 56, 250.255 (2003
    • (2003) Prostate , vol.56 , pp. 250-255
    • Van Der Aa, F.1    Roskams, T.2    Blyweert, W.3    De Ridder, D.4
  • 78
    • 78649416155 scopus 로고    scopus 로고
    • Role of connexin 43 in the maintenance of spontaneous activity in the guinea pig prostate gland
    • Dey, A., Kusljic, S., Lang, R. J. & Exintaris, B. Role of connexin 43 in the maintenance of spontaneous activity in the guinea pig prostate gland. Br. J. Pharmacol. 161, 1692.1707 (2010
    • (2010) Br. J. Pharmacol. , vol.161 , pp. 1692-1707
    • Dey, A.1    Kusljic, S.2    Lang, R.J.3    Exintaris, B.4
  • 79
    • 0028811564 scopus 로고
    • Morphogenetic aspects of normal and abnormal prostatic growth
    • Bonkhoff, H. & Remberger, K. Morphogenetic aspects of normal and abnormal prostatic growth. Pathol. Res. Pract. 191, 833-835 (1995
    • (1995) Pathol. Res. Pract. , vol.191 , pp. 833-835
    • Bonkhoff, H.1    Remberger, K.2
  • 80
    • 0034565921 scopus 로고    scopus 로고
    • Unique features of the basal cells of human prostate epithelium
    • El-Alfy, M., Pelletier, G., Hermo, L. S. & Labrie, F. Unique features of the basal cells of human prostate epithelium. Microsc. Res. Tech. 51, 436-446 (2000
    • (2000) Microsc. Res. Tech. , vol.51 , pp. 436-446
    • El-Alfy, M.1    Pelletier, G.2    Hermo, L.S.3    Labrie, F.4
  • 81
    • 0023740063 scopus 로고
    • Identification of a cellular receptor for transforming growth factor-β in rat ventral prostate and its negative regulation by androgens
    • Kyprianou, N. & Isaacs, J. T. Identification of a cellular receptor for transforming growth factor-β in rat ventral prostate and its negative regulation by androgens. Endocrinology 123, 2124-2131 (1988
    • (1988) Endocrinology , vol.123 , pp. 2124-2131
    • Kyprianou, N.1    Isaacs, J.T.2
  • 82
    • 0025650618 scopus 로고
    • Immunohistochemical localization of the androgen receptor in rat and human tissues
    • Sar, M., Lubahn, D. B., French, F. S. & Wilson, E. M. Immunohistochemical localization of the androgen receptor in rat and human tissues. Endocrinology 127, 3180-3186 (1990
    • (1990) Endocrinology , vol.127 , pp. 3180-3186
    • Sar, M.1    Lubahn, D.B.2    French, F.S.3    Wilson, E.M.4
  • 84
    • 0027358688 scopus 로고
    • Differential expression of gap junction connexins in endocrine and exocrine glands
    • Meda, P. et al. Differential expression of gap junction connexins in endocrine and exocrine glands. Endocrinology 133, 2371-2378 (1993
    • (1993) Endocrinology , vol.133 , pp. 2371-2378
    • Meda, P.1
  • 85
    • 0035111757 scopus 로고    scopus 로고
    • Developmental exposure to estrogens alters epithelial cell adhesion and gap junction proteins in the adult rat prostate
    • Habermann, H., Chang, W. Y., Birch, L., Mehta, P. & Prins, G. S. Developmental exposure to estrogens alters epithelial cell adhesion and gap junction proteins in the adult rat prostate. Endocrinology 142, 359-369 (2001
    • (2001) Endocrinology , vol.142 , pp. 359-369
    • Habermann, H.1    Chang, W.Y.2    Birch, L.3    Mehta, P.4    Prins, G.S.5
  • 86
    • 3042737001 scopus 로고    scopus 로고
    • Connexin43 and connexin26 form gap junctions, but not heteromeric channels in co-expressing cells
    • Gemel, J., Valiunas, V., Brink, P. R. & Beyer, E. C. Connexin43 and connexin26 form gap junctions, but not heteromeric channels in co-expressing cells. J. Cell Sci. 117, 2469-2480 (2004
    • (2004) J. Cell Sci. , vol.117 , pp. 2469-2480
    • Gemel, J.1    Valiunas, V.2    Brink, P.R.3    Beyer, E.C.4
  • 87
    • 0035140516 scopus 로고    scopus 로고
    • Regulation of the gap junction connexin 43 gene by androgens in the prostate
    • Huynh, H. T. et al. Regulation of the gap junction connexin 43 gene by androgens in the prostate. J. Mol. Endocrinol. 26, 1-10 (2001
    • (2001) J. Mol. Endocrinol. , vol.26 , pp. 1-10
    • Huynh, H.T.1
  • 88
    • 0035207430 scopus 로고    scopus 로고
    • Influence of neonatal estrogens on rat prostate development
    • Prins, G. S. et al. Influence of neonatal estrogens on rat prostate development. Reprod. Fertil. Dev. 13, 241-252 (2001
    • (2001) Reprod. Fertil. Dev. , vol.13 , pp. 241-252
    • Prins, G.S.1
  • 89
    • 33845391313 scopus 로고    scopus 로고
    • Androgen-Regulated formation and degradation of gap junctions in androgen-Responsive human prostate cancer cells
    • Mitra, S. et al. Androgen-regulated formation and degradation of gap junctions in androgen-responsive human prostate cancer cells. Mol. Biol. Cell 17, 5400-5416 (2006
    • (2006) Mol. Biol. Cell , vol.17 , pp. 5400-5416
    • Mitra, S.1
  • 90
    • 77953578556 scopus 로고    scopus 로고
    • Exploring cancer stem cell niche directed tumor growth
    • Sottoriva, A., Sloot, P. M., Medema, J. P. & Vermeulen, L. Exploring cancer stem cell niche directed tumor growth. Cell Cycle 9, 1472-1479 (2010
    • (2010) Cell Cycle , vol.9 , pp. 1472-1479
    • Sottoriva, A.1    Sloot, P.M.2    Medema, J.P.3    Vermeulen, L.4
  • 91
    • 61649093776 scopus 로고    scopus 로고
    • Profiling cancer stem cells in androgen-responsive and refractory human prostate tumor cell lines
    • Cocciadiferro, L. et al. Profiling cancer stem cells in androgen-responsive and refractory human prostate tumor cell lines. Ann. NY Acad. Sci. 1155, 257-262 (2009
    • (2009) Ann. NY Acad. Sci. , vol.1155 , pp. 257-262
    • Cocciadiferro, L.1
  • 92
    • 0030567963 scopus 로고    scopus 로고
    • Reduced connexin 43 expression in high grade, human prostatic adenocarcinoma cells
    • Tsai, H. et al. Reduced connexin 43 expression in high grade, human prostatic adenocarcinoma cells. Biochem. Biophys. Res. Commun. 227, 64-69 (1996
    • (1996) Biochem. Biophys. Res. Commun. , vol.227 , pp. 64-69
    • Tsai, H.1
  • 93
    • 79951639217 scopus 로고    scopus 로고
    • Prognostic value of connexin43 expression in patients with clinically localized prostate cancer
    • Benko, G. et al. Prognostic value of connexin43 expression in patients with clinically localized prostate cancer. Prostate Cancer Prostatic Dis. 14, 90-95 (2011
    • (2011) Prostate Cancer Prostatic Dis. , vol.14 , pp. 90-95
    • Benko, G.1
  • 94
    • 69449096005 scopus 로고    scopus 로고
    • Heterogeneity in cancer: Cancer stem cells versus clonal evolution
    • Shackleton, M., Quintana, E., Fearon, E. R. & Morrison, S. J. Heterogeneity in cancer: cancer stem cells versus clonal evolution. Cell 138, 822-829 (2009
    • (2009) Cell , vol.138 , pp. 822-829
    • Shackleton, M.1    Quintana, E.2    Fearon, E.R.3    Morrison, S.J.4
  • 95
    • 33746794230 scopus 로고    scopus 로고
    • A histone deacetylation-Dependent mechanism for transcriptional repression of the gap junction gene cx43 in prostate cancer cells
    • Hernandez, M. et al. A histone deacetylation-dependent mechanism for transcriptional repression of the gap junction gene cx43 in prostate cancer cells. Prostate 66, 1151-1161 (2006
    • (2006) Prostate , vol.66 , pp. 1151-1161
    • Hernandez, M.1
  • 96
    • 45849105217 scopus 로고    scopus 로고
    • ATRA enhances bystander effect of suicide gene therapy in the treatment of prostate cancer
    • Chen, W. et al. ATRA enhances bystander effect of suicide gene therapy in the treatment of prostate cancer. Urol. Oncol. 26, 397-405 (2008
    • (2008) Urol. Oncol. , vol.26 , pp. 397-405
    • Chen, W.1
  • 97
    • 0036296471 scopus 로고    scopus 로고
    • Intercellular communication and human prostate carcinogenesis
    • Carruba, G. et al. Intercellular communication and human prostate carcinogenesis. Ann. NY Acad. Sci. 963, 156-168 (2002
    • (2002) Ann. NY Acad. Sci. , vol.963 , pp. 156-168
    • Carruba, G.1
  • 98
    • 0036468221 scopus 로고    scopus 로고
    • Regulation of cell-To-Cell communication in non-tumorigenic and malignant human prostate epithelial cells
    • Carruba, G. et al. Regulation of cell-to-cell communication in non-tumorigenic and malignant human prostate epithelial cells. Prostate 50, 73-82 (2002
    • (2002) Prostate , vol.50 , pp. 73-82
    • Carruba, G.1
  • 99
    • 3242816322 scopus 로고    scopus 로고
    • Connexin 26 induces growth suppression, apoptosis and increased efficacy of doxorubicin in prostate cancer cells
    • Tanaka, M. & Grossman, H. B. Connexin 26 induces growth suppression, apoptosis and increased efficacy of doxorubicin in prostate cancer cells. Oncol. Rep. 11, 537-541 (2004
    • (2004) Oncol. Rep. , vol.11 , pp. 537-541
    • Tanaka, M.1    Grossman, H.B.2
  • 100
    • 0029865182 scopus 로고    scopus 로고
    • Gap-Junctional communication in normal and neoplastic prostate epithelial cells and its regulation by cAMP
    • Mehta, P. P. et al. Gap-junctional communication in normal and neoplastic prostate epithelial cells and its regulation by cAMP. Mol. Carcinog. 15, 18-32 (1996
    • (1996) Mol. Carcinog. , vol.15 , pp. 18-32
    • Mehta, P.P.1
  • 101
    • 84857159720 scopus 로고    scopus 로고
    • The gap junction protein Cx43 is involved in the bone-Targeted metastatic behaviour of human prostate cancer cells
    • Lamiche, C. et al. The gap junction protein Cx43 is involved in the bone-targeted metastatic behaviour of human prostate cancer cells. Clin. Exp. Metastasis 29, 111-122 (2012
    • (2012) Clin. Exp. Metastasis , vol.29 , pp. 111-122
    • Lamiche, C.1
  • 102
    • 84857635325 scopus 로고    scopus 로고
    • DU-145 prostate carcinoma cells that selectively transmigrate narrow obstacles express elevated levels of Cx43
    • Szpak, K. et al. DU-145 prostate carcinoma cells that selectively transmigrate narrow obstacles express elevated levels of Cx43. Cell. Mol. Biol. Lett. 16, 625-637 (2011
    • (2011) Cell Mol. Biol. Lett. , vol.16 , pp. 625-637
    • Szpak, K.1
  • 103
    • 0036299072 scopus 로고    scopus 로고
    • Connexin expression in nonneoplastic human prostate epithelial cells
    • Saladino, F. et al. Connexin expression in nonneoplastic human prostate epithelial cells. Ann. NY Acad. Sci. 963, 213-217 (2002
    • (2002) Ann. NY Acad. Sci. , vol.963 , pp. 213-217
    • Saladino, F.1
  • 104
    • 0024434175 scopus 로고
    • Prediction of metastatic potential in an animal model of prostate cancer: Flow cytometric quantification of cell surface charge
    • Carter, H. B., Partin, A. W. & Coffey, D. S. Prediction of metastatic potential in an animal model of prostate cancer: flow cytometric quantification of cell surface charge. J. Urol. 142, 1338-1341 (1989
    • (1989) J. Urol. , vol.142 , pp. 1338-1341
    • Carter, H.B.1    Partin, A.W.2    Coffey, D.S.3
  • 105
    • 38049132497 scopus 로고    scopus 로고
    • Genistein inhibits the contact-Stimulated migration of prostate cancer cells
    • Mie?kus, K. & Madeja, Z. Genistein inhibits the contact-stimulated migration of prostate cancer cells. Cell. Mol. Biol. Lett. 12, 348-361 (2007
    • (2007) Cell. Mol. Biol. Lett. , vol.12 , pp. 348-361
    • Miekus, K.1    Madeja, Z.2
  • 106
    • 48749122613 scopus 로고    scopus 로고
    • Cell motility affects the intensity of gap junctional coupling in prostate carcinoma and melanoma cell populations
    • Daniel-Wójcik, A. et al. Cell motility affects the intensity of gap junctional coupling in prostate carcinoma and melanoma cell populations. Int. J. Oncol. 33, 309-315 (2008
    • (2008) Int. J. Oncol. , vol.33 , pp. 309-315
    • Daniel-Wójcik, A.1
  • 107
    • 70350243052 scopus 로고    scopus 로고
    • Connexins, cell motility, and the cytoskeleton
    • Olk, S., Zoidl, G. & Dermietzel, R. Connexins, cell motility, and the cytoskeleton. Cell. Motil. Cytoskeleton 66, 1000-1016 (2009
    • (2009) Cell. Motil. Cytoskeleton , vol.66 , pp. 1000-1016
    • Olk, S.1    Zoidl, G.2    Dermietzel, R.3
  • 108
    • 77953585288 scopus 로고    scopus 로고
    • Gap junctions and connexins as therapeutic targets in cancer
    • Kandouz, M. & Batist, G. Gap junctions and connexins as therapeutic targets in cancer. Expert Opin. Ther. Targets 14, 681-692 (2010
    • (2010) Expert Opin. Ther. Targets , vol.14 , pp. 681-692
    • Kandouz, M.1    Batist, G.2
  • 110
    • 80053094078 scopus 로고    scopus 로고
    • Dietary flavonoids as cancer-preventive and therapeutic biofactors
    • Nishiumi, S. et al. Dietary flavonoids as cancer-preventive and therapeutic biofactors. Front. Biosci. (Schol. Ed.) 3, 1332-1362 (2011
    • (2011) Front. Biosci. (Schol. Ed.) , vol.3 , pp. 1332-1362
    • Nishiumi, S.1
  • 111
    • 0030965506 scopus 로고    scopus 로고
    • Flavonoids (apigenin, tangeretin) counteract tumor promoter-induced inhibition of intercellular communication of rat liver epithelial cells
    • Chaumontet, C. et al. Flavonoids (apigenin, tangeretin) counteract tumor promoter-induced inhibition of intercellular communication of rat liver epithelial cells. Cancer Lett. 114, 207-210 (1997
    • (1997) Cancer Lett. , vol.114 , pp. 207-210
    • Chaumontet, C.1
  • 112
    • 13244291976 scopus 로고    scopus 로고
    • Hierarchy of carcinoma cell responses to apigenin: Gap junctional coupling versus proliferation
    • Czyz?, J., Irmer, U., Zappe, C., Mauz, M. & Hülser, D. F. Hierarchy of carcinoma cell responses to apigenin: gap junctional coupling versus proliferation. Oncol. Rep. 11, 739-744 (2004
    • (2004) Oncol. Rep. , vol.11 , pp. 739-744
    • Czyz, J.1    Irmer, U.2    Zappe, C.3    Mauz, M.4    Hülser, D.F.5
  • 113
    • 13244277580 scopus 로고    scopus 로고
    • Flavonoid apigenin inhibits motility and invasiveness of carcinoma cells in vitro
    • Czyz?, J., Madeja, Z., Irmer, U., Korohoda, W. & Hülser, D. F. Flavonoid apigenin inhibits motility and invasiveness of carcinoma cells in vitro. Int. J. Cancer 114, 12-18 (2005
    • (2005) Int. J. Cancer , vol.114 , pp. 12-18
    • Czyz, J.1    Madeja, Z.2    Irmer, U.3    Korohoda, W.4    Hülser, D.F.5
  • 114
    • 28944449931 scopus 로고    scopus 로고
    • Connexins as targets for cancer chemoprevention and chemotherapy
    • King, T. J. & Bertram, J. S. Connexins as targets for cancer chemoprevention and chemotherapy. Biochim. Biophys. Acta 1719, 146-160 (2005
    • (2005) Biochim. Biophys. Acta , vol.1719 , pp. 146-160
    • King, T.J.1    Bertram, J.S.2
  • 115
    • 33845656981 scopus 로고    scopus 로고
    • Genistein and quercetin increase connexin43 and suppress growth of breast cancer cells
    • Conklin, C. M. et al. Genistein and quercetin increase connexin43 and suppress growth of breast cancer cells. Carcinogenesis 28, 93-100 (2007
    • (2007) Carcinogenesis , vol.28 , pp. 93-100
    • Conklin, C.M.1
  • 116
    • 56349123133 scopus 로고    scopus 로고
    • Apigenin inhibits growth and motility but increases gap junctional coupling intensity in rat prostate carcinoma (MAT-LyLu) cell populations
    • Czernik, M., Sroka, J., Madeja, Z. & Czyz?, J. Apigenin inhibits growth and motility but increases gap junctional coupling intensity in rat prostate carcinoma (MAT-LyLu) cell populations. Cell. Mol. Biol. Lett. 13, 327-338 (2008
    • (2008) Cell. Mol. Biol. Lett. , vol.13 , pp. 327-338
    • Czernik, M.1    Sroka, J.2    Madeja, Z.3    Czyz, J.4
  • 117
    • 4344564476 scopus 로고    scopus 로고
    • Lycopene: Modes of action to promote prostate health
    • Wertz, K., Siler, U. & Goralczyk, R. Lycopene: modes of action to promote prostate health. Arch. Biochem. Biophys. 430, 127-134 (2004
    • (2004) Arch. Biochem. Biophys. , vol.430 , pp. 127-134
    • Wertz, K.1    Siler, U.2    Goralczyk, R.3
  • 118
    • 0141513736 scopus 로고    scopus 로고
    • Lycopene increases urokinase receptor and fails to inhibit growth or connexin expression in a metastatically passaged prostate cancer cell line: A brief communication
    • Forbes, K., Gillette, K. & Sehgal, I. Lycopene increases urokinase receptor and fails to inhibit growth or connexin expression in a metastatically passaged prostate cancer cell line: a brief communication. Exp. Biol. Med. (Maywood) 228, 967-971 (2003
    • (2003) Exp. Biol. Med. (Maywood) , vol.228 , pp. 967-971
    • Forbes, K.1    Gillette, K.2    Sehgal, I.3
  • 119
    • 35648931498 scopus 로고    scopus 로고
    • Serum from rats fed red or yellow tomatoes induces Connexin43 expression independently from lycopene in a prostate cancer cell line
    • Gitenay, D. et al. Serum from rats fed red or yellow tomatoes induces Connexin43 expression independently from lycopene in a prostate cancer cell line. Biochem. Biophys. Res. Commun. 364, 578-582 (2007
    • (2007) Biochem. Biophys. Res. Commun. , vol.364 , pp. 578-582
    • Gitenay, D.1
  • 120
    • 2942691389 scopus 로고    scopus 로고
    • Stem cell origin of cancer and differentiation therapy
    • Sell, S. Stem cell origin of cancer and differentiation therapy. Crit. Rev. Oncol. Hematol. 51, 1-28 (2004
    • (2004) Crit. Rev. Oncol. Hematol. , vol.51 , pp. 1-28
    • Sell, S.1
  • 121
    • 30644479807 scopus 로고    scopus 로고
    • Folate-Linked nanoparticle-mediated suicide gene therapy in human prostate cancer and nasopharyngeal cancer with herpes simplex virus thymidine kinase
    • Hattori, Y. & Maitani, Y. Folate-linked nanoparticle-mediated suicide gene therapy in human prostate cancer and nasopharyngeal cancer with herpes simplex virus thymidine kinase. Cancer Gene Ther. 12, 796-809 (2005
    • (2005) Cancer Gene Ther. , vol.12 , pp. 796-809
    • Hattori, Y.1    Maitani, Y.2
  • 122
    • 33846948256 scopus 로고    scopus 로고
    • Connexin43 increases the sensitivity of prostate cancer cells to TNFα-induced apoptosis
    • Wang, M., Berthoud, V. M. & Beyer, E. C. Connexin43 increases the sensitivity of prostate cancer cells to TNFα-induced apoptosis. J. Cell Sci. 120, 320-329 (2007
    • (2007) J. Cell Sci. , Issue.120 , pp. 320-329
    • Wang, M.1    Berthoud, V.M.2    Beyer, E.C.3
  • 123
    • 0037147288 scopus 로고    scopus 로고
    • Impaired trafficking of connexins in androgen-independent human prostate cancer cell lines and its mitigation by α-catenin
    • Govindarajan, R. et al. Impaired trafficking of connexins in androgen-independent human prostate cancer cell lines and its mitigation by α-catenin. J. Biol. Chem. 277, 50087-50097 (2002
    • (2002) J. Biol. Chem. , vol.277 , pp. 50087-50097
    • Govindarajan, R.1
  • 124
    • 35348841286 scopus 로고    scopus 로고
    • Combination of non-viral connexin 43 gene therapy and docetaxel inhibits the growth of human prostate cancer in mice
    • Fukushima, M., Hattori, Y., Yoshizawa, T. & Maitani, Y. Combination of non-viral connexin 43 gene therapy and docetaxel inhibits the growth of human prostate cancer in mice. Int. J. Oncol. 30, 225-231 (2007
    • (2007) Int. J. Oncol. , vol.30 , pp. 225-231
    • Fukushima, M.1    Hattori, Y.2    Yoshizawa, T.3    Maitani, Y.4
  • 125
    • 79958237900 scopus 로고    scopus 로고
    • Fenofibrate attenuates contact-stimulated cell motility and gap junctional coupling in DU-145 human prostate cancer cell populations
    • Wybieralska, E. et al. Fenofibrate attenuates contact-stimulated cell motility and gap junctional coupling in DU-145 human prostate cancer cell populations. Oncol. Rep. 26, 447-453 (2011
    • (2011) Oncol. Rep. , vol.26 , pp. 447-453
    • Wybieralska, E.1
  • 126
    • 84860608896 scopus 로고    scopus 로고
    • Partial mesenchymal to epithelial reverting transition in breast and prostate cancer metastases
    • Chao, Y., Wu, Q., Acquafondata, M., Dhir, R. & Wells, A. Partial mesenchymal to epithelial reverting transition in breast and prostate cancer metastases. Cancer Microenviron. http://dx.doi.org/10.1007/s12307-011-0085-4.
    • Cancer Microenviron.
    • Chao, Y.1    Wu, Q.2    Acquafondata, M.3    Dhir, R.4    Wells, A.5


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