Ignored hallmarks of carcinogenesis: Stem cells and cell-cell communication

Annals of the New York Academy of Sciences

Volumn 1028, Issue , 2004, Pages 192-201

  Trosko, James E ^a   Chang, Chia Cheng ^a   Upham, Brad L ^a   Tai, Mei Hu ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Carcinogenesis; Cell cell communication; Mutagenesis; Stem cell

Indexed keywords

APOPTOSIS; CANCER INVASION; CARCINOGENESIS; CELL COMMUNICATION; CELL DEATH; CELL JUNCTION; CLONOGENESIS; CONFERENCE PAPER; EPIGENETICS; GENE MUTATION; GROWTH STIMULATION; HUMAN; METASTASIS POTENTIAL; NONHUMAN; SIGNAL TRANSDUCTION; STEM CELL;

EID: 14944382346     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1322.023     Document Type: Conference Paper

References (37)

1. HANAHAN, D. & R.A. WEINBERG. 2000. The hallmarks of cancer. Cell 100: 57-70.
2. PITOT, H.C., T.L. GOLDSWORTHY & S. MORAN. 1981. The natural history of carcinogenesis: implications of experimental carcinogenesis in the genesis of human cancer. J. Supramol. Struct. Cell Biochem. 17: 133-146.
3. WEINSTEIN, I.B., C.S. GATTONI, P. KIRSCHMEIER, et al. 1984. Multistage carcinogenesis involves multiple genes and multiple mechanisms. J. Cell Physiol. Suppl. 3: 127-137.
4. TROSKO, J.E., C.C. CHANG, B.V. MADHUKAR & E. DUPONT. 1996. Intercellular communication: a paradigm for the interpretation of the initiation/promotion/progress model of carcinogenesis. In Chemical Induction of Cancer: Modulation and Combination Effects. Arcos, J.C., Ed.: 205-225. Birkkhauser. Boston.
5. POTTER, V.R. 1978. Phenotypic diversity in experimental hepatomas: the concept of partially blocked ontogeny. Br. J. Cancer. 38: 1-23.
6. LOEWENSTEIN, W.R. 1966. Permeability of membrane junctions. Ann. N.Y. Acad. Sci. 137: 441-472.
7. TROSKO, J.E. 2003. The role of stem cells and gap junctional intercellular communication in carcinogenesis. J. Biochem. Mol. Biol. 36: 43-48.
8. TROSKO, J.E. & C.C. CHANG. 1988. Nongenotoxic mechanisms in carcinogenesis: Role of inhibited intercellular communication. In Banbury Report 31: Carcinogen Risk Assessment: New Directions in the Quantitative and Qualitative Assessment Aspects. Hart, R.W. & F.D. Hoerger, Eds.: 139-170. Cold Spring Harbor Laboratory. Cold Spring Harbor, New York.
9. TROSKO, J.E. 2001. Commentary: is the concept of "tumor promotion" a useful paradigm? Mol. Carcinog. 30: 131-137.
10. TROSKO, J.E. & R.J. RUCH. 2002. Gap junctions as targets for cancer chemoprevention and chemotherapy. Curr. Drug Targets 3: 465-482.
11. YOTTI, L.P., C.C. CHANG & J.E. TROSKO. 1979. Elimination of metabolic cooperation in Chinese hamster cells by a tumor promoter. Science 206: 1089-1091.
12. TROSKO, J.E., C.C. CHANG, B.V. MADHUKAR & E. DUPONT. 1993. Oncogenes, tumor suppressor genes, and intercellular communication in the "oncogeny as partially blocked ontogeny" hypothesis. In New Frontiers in Cancer Causation. Iversen, O.H., Ed.: 181-197. Taylor and Francis Publishers. Washington, D.C.
13. LAND, H., L.F. PARADA & R.A. WEINBERG. 1983. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature 304: 596-602.
14. TROSKO, J.E., C.C. CHANG, M.R. WILSON, et al. 2000. Gap junctions and the regulation of cellular function of stem cells during development and differentiation. Methods 20: 245-264.
15. SPRADLING, A., D. DRUMMOND-BARBOSA & T. KAI. 2001. Stem cells find their niche. Nature 414: 98-104.
16. EVANS, W.H.& E.M. MARTIN-PATRICIA. 2002. Gap junctions: structure and function (Review). Mol. Membrane Biol. 19: 121-136.
17. CHANG, C.C., J.E. TROSKO, M.H. EL-FOULY, et al. 1987. Contact insensitivity of a sub-population of normal human fetal kidney epithelial cells and of human carcinoma cell lines. Cancer Res. 47: 1634-1645.
18. KAO, C.Y., K. NOMATA, C.S. OAKLEY, et al. 1995. Two types of normal human breast epithelial cells derived from reduction mammoplasty: phenotypic characterization and response to SV40 transfection. Carcinogenesis 16: 531-538.
19. TAI, M.H., B. MADHUKAR, L.K. OLSON, et al. 2003. Characterization of gap junctional intercellular communication in immortalized human ductal epithelial cells with stem cell characteristics. Pancreas 26: e18-26.
20. CHANG, C.C. Personal communication.
21. MATIC, M., I.N. PETROV, S. CHEN, et al. 1997. Stem cells of the corneal epithelium lack connexins and metabolite transfer capacity. Differentiation 61: 251-260.
22. GRUETERICH, M. & S.C.G. TSENG. 2002. Human limbal progenitor cells expanded on intact amniotic membrane ex vivo. Arch. Ophthalmol. 120: 783-790.
23. MATIC, M., W.H. EVANS, P.R. BRINK & M. SIMON. 2002. Epidermal stem cells do not communicate through gap junctions. J. Invest. Dermatol. 118: 110-116.
24. JACOBI, C., J. LEIPZIGER, R. NITSCHKE, et al. 1998. No evidence for cell-to-cell coupling in rat colonic crypts: studies with Lucifer Yellow and with photobleaching. Pflugers Arch. Eur. J. Physiol. 436: 83-89.
25. MATIC, M. & M. SIMON. 2003. Label-retaining cells (presumptive stem cells) of mice vibrissae do not express gap junction protein connexin 43. J. Investig. Dermatol. Symp. Proc. 8: 91-95.
26. LO, C.W. & N.B. GILULA. 1979. Gap junctional communication in the preimplantation mouse embryo. Cell 18: 399-409.
27. BARCELLOS-HOFF, M.H. & A.L. BROOKS. 2001. Extracellular signaling through the microenvironment: a hypothesis relating carcinogenesis, bystander effects, and genomic instability. Radiat Res. 156: 618-627.
28. KING, T.J., L.H. FUKUSHIMA, T.A. DONLON, et al. 2000. Correlation between growth control, neoplastic potential and endogenous connexin43 expression in Hela cell lines: implications for tumor progression. Carcinogenesis 21: 311-315.
29. MOMIYAMA, M., Y. OMORI, Y. ISHIZAKI, et al. 2003. Connexin26-mediated gap junctional communication reverses the malignant phenotype of MCF-7 breast cancer cells. Cancer Sci. 94: 501-507.
30. TROSKO, J.E. & R.J. RUCH. 1998. Cell-cell communication in carcinogenesis. Front. Biosci. 3: 208-236.
31. UPHAM, B.L., J. SUZUKI, G. CHEN, et al. 2003. Reduced gap junctional intercellular communication and altered biological effects in mouse osteoblast and rat liver oval cell lines transfected with dominant-negative connexin 43. Mol. Carcinog. 37: 192-201.
32. LEE, G.H. 2000. Paradoxical effects of Phenobarbital on mouse hepatocarcinogenesis. Toxicol. Pathol. 28: 215-225.
33. KLAUNIG, J.E. & R.J. RUCH. 1987. Strain and species effects on the inhibition of hepatocyte intercellular communication by liver tumor promoters. Cancer Lett. 36: 161-168.
34. BRUZZONE, R., T.W. WHITE & E.L. PAUL. 1996. Connection with connexins: the molecular basis of direct intercellular signaling. Eur. J. Biochem. 238: 1-27.
35. CHANG, C.C., W. SUN, A. CRUZ, et al. 2001. A human breast epithelial cell type with stem cell characteristics as target cells for carcinogenesis. Radiat. Res. 155: 201-207.
36. RUCH, R.J., B.V. MADHUKAR, J.E. TROSKO & J.E. KLAUNIG. 1993. Reversal of ras-induced inhibition of gap-junctional intercellular communication, transformation, and tumorigenesis by lovastatin. Mol. Carcinog. 7: 50-59.
37. TROSKO, J.E. et al. 1998. Modulation of gap junction intercellular communication by tumor promoting chemicals, oncogenes and growth factors during carcinogenesis. In Modern Cell Biology, Vol. 7: Gap Junctions. E.L. Hertberg & R.G. Johnson, Eds.: 435-448. Alan R. Liss. New York.