메뉴 건너뛰기




Volumn 47, Issue 6, 2008, Pages 403-409

The inhibitory effect of connexin 32 gene on metastasis in renal cell carcinoma

Author keywords

Connexin 32; Hypoxia; Metastasis; Renal cell carcinoma

Indexed keywords

CONNEXIN 32; PROTEIN TYROSINE KINASE; VASCULOTROPIN;

EID: 44949185610     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20396     Document Type: Article
Times cited : (16)

References (35)
  • 1
    • 0033978220 scopus 로고    scopus 로고
    • Systemic therapy for renal cell carcinoma
    • Motzer RJ, Russo P. Systemic therapy for renal cell carcinoma. J Urol 2000;163:408-417.
    • (2000) J Urol , vol.163 , pp. 408-417
    • Motzer, R.J.1    Russo, P.2
  • 3
    • 2342583527 scopus 로고    scopus 로고
    • Searching for the hereshary causes of renal-cell carcinoma
    • Pavlovich CP, Schmidt LS. Searching for the hereshary causes of renal-cell carcinoma. Nat Rev Cancer 2004;4:381-393.
    • (2004) Nat Rev Cancer , vol.4 , pp. 381-393
    • Pavlovich, C.P.1    Schmidt, L.S.2
  • 4
    • 3042609752 scopus 로고    scopus 로고
    • Pathological and molecular biological aspects of the renal epithelial neoplasms, up-to-date
    • Nagashima Y, Inayama Y, Kato Y, et al. Pathological and molecular biological aspects of the renal epithelial neoplasms, up-to-date. Pathol Int 2004;54:377-386
    • (2004) Pathol Int , vol.54 , pp. 377-386
    • Nagashima, Y.1    Inayama, Y.2    Kato, Y.3
  • 5
    • 0029090362 scopus 로고
    • Phase III randomized trial of interleukin-2 with or without lymphokine-activated killer cells in the treatment of patients with advanced renal cell carcinoma
    • Law TM, Motzer RJ, Mazumdar M, et al. Phase III randomized trial of interleukin-2 with or without lymphokine-activated killer cells in the treatment of patients with advanced renal cell carcinoma. Cancer 1995;76:824-832.
    • (1995) Cancer , vol.76 , pp. 824-832
    • Law, T.M.1    Motzer, R.J.2    Mazumdar, M.3
  • 6
    • 0000299698 scopus 로고    scopus 로고
    • Cell-cell communication in carcinogenesis
    • Trosko JE, Ruch RJ. Cell-cell communication in carcinogenesis. Front Biosci 1998;3:d208-d236.
    • (1998) Front Biosci , vol.3
    • Trosko, J.E.1    Ruch, R.J.2
  • 7
    • 0036873006 scopus 로고    scopus 로고
    • Connexins and cancer
    • Mesnil M. Connexins and cancer. Biol Cell 2002;94:493-500.
    • (2002) Biol Cell , vol.94 , pp. 493-500
    • Mesnil, M.1
  • 8
    • 0026694158 scopus 로고
    • Expression of Cx26, Cx32 and Cx43 gap junction proteins in normal and neoplastic human tissues
    • Wilgenbus KK, Kirkpatrick CJ, Knuechel R, Willecke K, Traub O. Expression of Cx26, Cx32 and Cx43 gap junction proteins in normal and neoplastic human tissues. Int J Cancer 1992;51:522-529.
    • (1992) Int J Cancer , vol.51 , pp. 522-529
    • Wilgenbus, K.K.1    Kirkpatrick, C.J.2    Knuechel, R.3    Willecke, K.4    Traub, O.5
  • 9
    • 0023551497 scopus 로고
    • Connexin43: A protein from rat heart homologous to a gap junction protein from liver
    • Beyer EC, Paul DL, Goodenough DA. Connexin43: A protein from rat heart homologous to a gap junction protein from liver. J Cell Biol 1987;105:2621-2629.
    • (1987) J Cell Biol , vol.105 , pp. 2621-2629
    • Beyer, E.C.1    Paul, D.L.2    Goodenough, D.A.3
  • 10
    • 0038693736 scopus 로고    scopus 로고
    • Down-regulation of connexin 32 gene expression through DNA methylation in a human renal cell carcinoma cell
    • Hirai A, Yano T, Nishikawa K, et al. Down-regulation of connexin 32 gene expression through DNA methylation in a human renal cell carcinoma cell. Am J Nephrol 2003;23: 172-177.
    • (2003) Am J Nephrol , vol.23 , pp. 172-177
    • Hirai, A.1    Yano, T.2    Nishikawa, K.3
  • 11
    • 0037213712 scopus 로고    scopus 로고
    • Tumor-suppressive effect of connexin 32 in renal cell carcinoma from maintenance hemodialysis patients
    • Yano T, Ito F, Satoh H, et al. Tumor-suppressive effect of connexin 32 in renal cell carcinoma from maintenance hemodialysis patients. Kidney Int 2003;63:381.
    • (2003) Kidney Int , vol.63 , pp. 381
    • Yano, T.1    Ito, F.2    Satoh, H.3
  • 12
    • 3142676384 scopus 로고    scopus 로고
    • Negative growth control of renal cell carcinoma cell by connexin 32: Possible involvement of Her-2
    • Fujimoto E, Satoh H, Negishi E, et al. Negative growth control of renal cell carcinoma cell by connexin 32: Possible involvement of Her-2. Mol Carcinog 2004;40:135-142.
    • (2004) Mol Carcinog , vol.40 , pp. 135-142
    • Fujimoto, E.1    Satoh, H.2    Negishi, E.3
  • 13
    • 19944381865 scopus 로고    scopus 로고
    • Connexin32 as a tumor suppressor gene in a metastatic renal cell carcinoma cell line
    • Fujimoto E, Sato H, Shirai S, et al. Connexin32 as a tumor suppressor gene in a metastatic renal cell carcinoma cell line. Oncogene 2005;24:3684-3690.
    • (2005) Oncogene , vol.24 , pp. 3684-3690
    • Fujimoto, E.1    Sato, H.2    Shirai, S.3
  • 14
    • 33645241296 scopus 로고    scopus 로고
    • Connexin 32 down-regulates the fibrinolytic factors in metastatic renal cell carcinoma cells
    • Hagiwara H, Sato H, Shirai S, et al. Connexin 32 down-regulates the fibrinolytic factors in metastatic renal cell carcinoma cells. Life Sci 2006;78:2249-2254.
    • (2006) Life Sci , vol.78 , pp. 2249-2254
    • Hagiwara, H.1    Sato, H.2    Shirai, S.3
  • 15
    • 0032446733 scopus 로고    scopus 로고
    • A simplified model of hypoxic injury in primary cultured rat hepatocytes
    • Kamiya T, Kwon AH, Kanemaki T, et al. A simplified model of hypoxic injury in primary cultured rat hepatocytes. In Vitro Cell Dev Biol Anim 1998;34:131-137.
    • (1998) In Vitro Cell Dev Biol Anim , vol.34 , pp. 131-137
    • Kamiya, T.1    Kwon, A.H.2    Kanemaki, T.3
  • 16
    • 0029787205 scopus 로고    scopus 로고
    • Novel metastasis model of human lung cancer in SCID mice depleted of NK cells
    • Yano S, Nishioka Y, Izumi K, et al. Novel metastasis model of human lung cancer in SCID mice depleted of NK cells. Int J Cancer 1996;67:211-217.
    • (1996) Int J Cancer , vol.67 , pp. 211-217
    • Yano, S.1    Nishioka, Y.2    Izumi, K.3
  • 17
    • 3042623408 scopus 로고    scopus 로고
    • A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth
    • Martin SS, Ridgeway AG, Pinkas J, et al. A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth. Oncogene 2004;23:4641-4645.
    • (2004) Oncogene , vol.23 , pp. 4641-4645
    • Martin, S.S.1    Ridgeway, A.G.2    Pinkas, J.3
  • 18
    • 0030788411 scopus 로고    scopus 로고
    • The urokinase-type plasminogen activator system in cancer metastasis: A review
    • Andreasen PA, Kjoller L, Christensen L, Duffy MJ. The urokinase-type plasminogen activator system in cancer metastasis: A review. Int J Cancer 1997;72:1-22.
    • (1997) Int J Cancer , vol.72 , pp. 1-22
    • Andreasen, P.A.1    Kjoller, L.2    Christensen, L.3    Duffy, M.J.4
  • 19
    • 0038663072 scopus 로고    scopus 로고
    • Urokinase-type plasminogen activator expression correlates with tumor angiogenesis and poor outcome in gastric cancer
    • Kaneko T, Konno H, Baba M, Tanaka T, Nakamura S. Urokinase-type plasminogen activator expression correlates with tumor angiogenesis and poor outcome in gastric cancer. Cancer Sci 2003;94:43-49.
    • (2003) Cancer Sci , vol.94 , pp. 43-49
    • Kaneko, T.1    Konno, H.2    Baba, M.3    Tanaka, T.4    Nakamura, S.5
  • 20
    • 33748849657 scopus 로고    scopus 로고
    • The role of the hypoxia-inducible factor in tumor metabolism growth and invasion
    • Brahimi-Horn C, Pouyssegur J. The role of the hypoxia-inducible factor in tumor metabolism growth and invasion. Bull Cancer 2006;93:E73-E80.
    • (2006) Bull Cancer , vol.93
    • Brahimi-Horn, C.1    Pouyssegur, J.2
  • 21
    • 0030498734 scopus 로고    scopus 로고
    • Angiogenesis and metastasis
    • Ellis LM, Fidler IJ. Angiogenesis and metastasis. Eur J Cancer 1996;32A:2451-2460.
    • (1996) Eur J Cancer , vol.32 A , pp. 2451-2460
    • Ellis, L.M.1    Fidler, I.J.2
  • 22
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia - a key regulatory factor in tumour growth
    • Harris AL. Hypoxia - a key regulatory factor in tumour growth. Nat Rev Cancer 2002;2:38-47.
    • (2002) Nat Rev Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 23
    • 0141988698 scopus 로고    scopus 로고
    • Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia
    • Sowter HM, Raval RR, Moore JW, Ratcliffe PJ, Harris AL. Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia. Cancer Res 2003;63:6130-6134.
    • (2003) Cancer Res , vol.63 , pp. 6130-6134
    • Sowter, H.M.1    Raval, R.R.2    Moore, J.W.3    Ratcliffe, P.J.4    Harris, A.L.5
  • 24
    • 0034212905 scopus 로고    scopus 로고
    • Plonowski A, Serially AV, Nagy A, Kiaris H, Hebert F, Halmos G. Inhibition of metastatic renal cell carcinomas expressing somatostatin receptors by a targeted cytotoxic analogue of somatostatin AN-238. Cancer Res 2000;60:2996-3001.
    • Plonowski A, Serially AV, Nagy A, Kiaris H, Hebert F, Halmos G. Inhibition of metastatic renal cell carcinomas expressing somatostatin receptors by a targeted cytotoxic analogue of somatostatin AN-238. Cancer Res 2000;60:2996-3001.
  • 25
    • 4444311880 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1alpha as a cancer drug target
    • Powis G, Kirkpatrick L. Hypoxia inducible factor-1alpha as a cancer drug target. Mol Cancer Ther 2004;3:647-654.
    • (2004) Mol Cancer Ther , vol.3 , pp. 647-654
    • Powis, G.1    Kirkpatrick, L.2
  • 26
    • 18844444774 scopus 로고    scopus 로고
    • HIF-1alpha, STAT3, CBP/ p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas
    • Gray MJ, Zhang J, Ellis LM, et al. HIF-1alpha, STAT3, CBP/ p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas. Oncogene 2005;24:3110-3120.
    • (2005) Oncogene , vol.24 , pp. 3110-3120
    • Gray, M.J.1    Zhang, J.2    Ellis, L.M.3
  • 27
    • 23644433002 scopus 로고    scopus 로고
    • Contribution of the Src family of kinases to the appearance of malignant phenotypes in renal cancer cells
    • Yonezawa Y, Nagashima Y, Sato H, et al. Contribution of the Src family of kinases to the appearance of malignant phenotypes in renal cancer cells. Mol Carcinog 2005;43: 188-197.
    • (2005) Mol Carcinog , vol.43 , pp. 188-197
    • Yonezawa, Y.1    Nagashima, Y.2    Sato, H.3
  • 28
    • 33746851956 scopus 로고    scopus 로고
    • Tumor metastasis: Mechanistic insights and clinical challenges
    • Steeg PS. Tumor metastasis: Mechanistic insights and clinical challenges. Nat Med 2006;12:895-904.
    • (2006) Nat Med , vol.12 , pp. 895-904
    • Steeg, P.S.1
  • 29
    • 0347029631 scopus 로고    scopus 로고
    • Tumor hypoxia: A target for selective cancer therapy
    • Kizaka-Kondoh S, lnoue M, Harada H, Hiraoka M. Tumor hypoxia: A target for selective cancer therapy. Cancer Sci 2003;94:1021-1028.
    • (2003) Cancer Sci , vol.94 , pp. 1021-1028
    • Kizaka-Kondoh, S.1    lnoue, M.2    Harada, H.3    Hiraoka, M.4
  • 30
    • 3042685205 scopus 로고    scopus 로고
    • The urokinase plasminogen activator system: A rich source of tumour markers for the individualised management of patients with cancer
    • Duffy MJ, Duggan C. The urokinase plasminogen activator system: A rich source of tumour markers for the individualised management of patients with cancer. Clin Biochem 2004;37:541-548.
    • (2004) Clin Biochem , vol.37 , pp. 541-548
    • Duffy, M.J.1    Duggan, C.2
  • 31
    • 0034816408 scopus 로고    scopus 로고
    • Human MCF10A mammary epithelial cells undergo apoptosis following actin depolymerization that is independent of attachment and rescued by Bcl-2
    • Martin SS, Leder P. Human MCF10A mammary epithelial cells undergo apoptosis following actin depolymerization that is independent of attachment and rescued by Bcl-2. Mol Cell Biol 2001;21:6529-6536.
    • (2001) Mol Cell Biol , vol.21 , pp. 6529-6536
    • Martin, S.S.1    Leder, P.2
  • 32
    • 3042830441 scopus 로고    scopus 로고
    • Regulation of Bcl-2 proteins during anoikis and amorphosis
    • Martin SS, Vuori K. Regulation of Bcl-2 proteins during anoikis and amorphosis. Biochim Biophys Acta 2004;1692: 145-157.
    • (2004) Biochim Biophys Acta , vol.1692 , pp. 145-157
    • Martin, S.S.1    Vuori, K.2
  • 33
    • 0032984589 scopus 로고    scopus 로고
    • Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells
    • Catlett-Falcone R, Landowski TH, Oshiro MM, et al. Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity 1999;10: 105-115.
    • (1999) Immunity , vol.10 , pp. 105-115
    • Catlett-Falcone, R.1    Landowski, T.H.2    Oshiro, M.M.3
  • 34
    • 33744979530 scopus 로고    scopus 로고
    • Inhibition of Src activity enhances the tumor-suppressive effect of the connexin 32 gene in Caki-1 renal cancer cells
    • Fujimoto E, Sato H, Shirai S, et al. Inhibition of Src activity enhances the tumor-suppressive effect of the connexin 32 gene in Caki-1 renal cancer cells. Oncol Rep 2006;15:1359-1365.
    • (2006) Oncol Rep , vol.15 , pp. 1359-1365
    • Fujimoto, E.1    Sato, H.2    Shirai, S.3
  • 35
    • 33947155835 scopus 로고    scopus 로고
    • Connexin 32 potentiates vinblastine-induced cytotoxicity in renal cell carcinoma cells
    • Sato H, Senba H, Virgona N, et al. Connexin 32 potentiates vinblastine-induced cytotoxicity in renal cell carcinoma cells. Mol Carcinog 2007;46:215-224.
    • (2007) Mol Carcinog , vol.46 , pp. 215-224
    • Sato, H.1    Senba, H.2    Virgona, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.