-
1
-
-
0037155837
-
Direct activation of mitochondrial apoptosis machinery by c-Jun N-terminal kinase in adult cardiac myocytes
-
Aoki H., Kang P.M., Hampe J., Yoshimura K., Noma T., Matsuzaki M., Izumo S. Direct activation of mitochondrial apoptosis machinery by c-Jun N-terminal kinase in adult cardiac myocytes. J. Biol. Chem. 2002, 277:10244-10250.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 10244-10250
-
-
Aoki, H.1
Kang, P.M.2
Hampe, J.3
Yoshimura, K.4
Noma, T.5
Matsuzaki, M.6
Izumo, S.7
-
2
-
-
0036885110
-
On the pathogenic role of brain-sequestered alphabeta CD8+ T cells in experimental cerebral malaria
-
Belnoue E., Kayibanda M., Vigario A.M., Deschemin J.C., van Rooijen N., Viguier M., Snounou G., Rénia L. On the pathogenic role of brain-sequestered alphabeta CD8+ T cells in experimental cerebral malaria. J. Immunol. 2002, 169:6369-6375.
-
(2002)
J. Immunol.
, vol.169
, pp. 6369-6375
-
-
Belnoue, E.1
Kayibanda, M.2
Vigario, A.M.3
Deschemin, J.C.4
van Rooijen, N.5
Viguier, M.6
Snounou, G.7
Rénia, L.8
-
3
-
-
33748614868
-
PERK, pAkt and pBad: a possible role in cell proliferation and sustained cellular survival during tumorigenesis and tumor progression in ENU induced transplacental glioma rat model
-
Bhaskara V.K., Sundaram C., Babu P.P. pERK, pAkt and pBad: a possible role in cell proliferation and sustained cellular survival during tumorigenesis and tumor progression in ENU induced transplacental glioma rat model. Neurochem. Res. 2006, 31:1163-1170.
-
(2006)
Neurochem. Res.
, vol.31
, pp. 1163-1170
-
-
Bhaskara, V.K.1
Sundaram, C.2
Babu, P.P.3
-
4
-
-
13444301318
-
Specific pathophysiological functions of JNK isoforms in the brain
-
Brecht S., Kirchhof R., Chromik A., Willesen M., Nicolaus T., Raivich G., Wessig J., Waetzig V., Goetz M., Claussen M., Pearse D., Kuan C.Y., Vaudano E., Behrens A., Wagner E., Flavell R.A., Davis R.J., Herdegen T. Specific pathophysiological functions of JNK isoforms in the brain. Eur. J. Neurosci. 2005, 21:363-377.
-
(2005)
Eur. J. Neurosci.
, vol.21
, pp. 363-377
-
-
Brecht, S.1
Kirchhof, R.2
Chromik, A.3
Willesen, M.4
Nicolaus, T.5
Raivich, G.6
Wessig, J.7
Waetzig, V.8
Goetz, M.9
Claussen, M.10
Pearse, D.11
Kuan, C.Y.12
Vaudano, E.13
Behrens, A.14
Wagner, E.15
Flavell, R.A.16
Davis, R.J.17
Herdegen, T.18
-
5
-
-
60849105665
-
JNK regulates APP cleavage and degradation in a model of Alzheimer's disease
-
Colombo A., Bastone A., Ploia C., Sclip A., Salmona M., Forloni G., Borsello T. JNK regulates APP cleavage and degradation in a model of Alzheimer's disease. Neurobiol. Dis. 2009, 33:518-525.
-
(2009)
Neurobiol. Dis.
, vol.33
, pp. 518-525
-
-
Colombo, A.1
Bastone, A.2
Ploia, C.3
Sclip, A.4
Salmona, M.5
Forloni, G.6
Borsello, T.7
-
6
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis R.J Signal transduction by the JNK group of MAP kinases. Cell 2000, 103:239-252.
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
7
-
-
0036213195
-
Cerebral malaria: the contribution of studies in animal models to our understanding of immunopathogenesis
-
de Souza J.B., Riley E.M. Cerebral malaria: the contribution of studies in animal models to our understanding of immunopathogenesis. Microbes Infect. 2002, 4:291-300.
-
(2002)
Microbes Infect.
, vol.4
, pp. 291-300
-
-
de Souza, J.B.1
Riley, E.M.2
-
8
-
-
0035991520
-
Macrophages/microglial cells in patients with cerebral malaria
-
Deininger M.H., Kremsner P.G., Meyermann R., Schluesener H. Macrophages/microglial cells in patients with cerebral malaria. Eur. Cytokine Netw. 2002, 13:173-185.
-
(2002)
Eur. Cytokine Netw.
, vol.13
, pp. 173-185
-
-
Deininger, M.H.1
Kremsner, P.G.2
Meyermann, R.3
Schluesener, H.4
-
9
-
-
0141953270
-
A JNK-dependent pathway is required for TNF alpha-induced apoptosis
-
Deng Y., Ren X., Yang L., Lin Y., Wu X. A JNK-dependent pathway is required for TNF alpha-induced apoptosis. Cell 2003, 115:61-70.
-
(2003)
Cell
, vol.115
, pp. 61-70
-
-
Deng, Y.1
Ren, X.2
Yang, L.3
Lin, Y.4
Wu, X.5
-
10
-
-
0023189866
-
Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria
-
Grau G.E., Fajardo L.F., Piguet P.F., Allet B., Lambert P.H., Vassalli P. Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria. Science 1987, 237:1210-1212.
-
(1987)
Science
, vol.237
, pp. 1210-1212
-
-
Grau, G.E.1
Fajardo, L.F.2
Piguet, P.F.3
Allet, B.4
Lambert, P.H.5
Vassalli, P.6
-
11
-
-
0029012476
-
A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death
-
Ham J., Babij C., Whitfield J., Pfarr C.M., Lallemand D., Yaniv M., Rubin L.L. A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death. Neuron 1995, 14:927-939.
-
(1995)
Neuron
, vol.14
, pp. 927-939
-
-
Ham, J.1
Babij, C.2
Whitfield, J.3
Pfarr, C.M.4
Lallemand, D.5
Yaniv, M.6
Rubin, L.L.7
-
12
-
-
0031025602
-
Depletion of CD4+ or CD8+ T-cells prevents Plasmodium berghei induced cerebral malaria in end-stage disease
-
Hermsen C., van de Wiel T., Mommers E., Sauerwein R., Eling W. Depletion of CD4+ or CD8+ T-cells prevents Plasmodium berghei induced cerebral malaria in end-stage disease. Parasitology 1997, 114:7-12.
-
(1997)
Parasitology
, vol.114
, pp. 7-12
-
-
Hermsen, C.1
van de Wiel, T.2
Mommers, E.3
Sauerwein, R.4
Eling, W.5
-
13
-
-
0036710505
-
The c-Jun N-terminal kinases in cerebral microglia: immunological functions in the brain
-
Hidding U., Mielke K., Waetzig V., Brecht S., Hanisch U., Behrens A., Wagner E., Herdegen T. The c-Jun N-terminal kinases in cerebral microglia: immunological functions in the brain. Biochem. Pharmacol. 2002, 64:781-788.
-
(2002)
Biochem. Pharmacol.
, vol.64
, pp. 781-788
-
-
Hidding, U.1
Mielke, K.2
Waetzig, V.3
Brecht, S.4
Hanisch, U.5
Behrens, A.6
Wagner, E.7
Herdegen, T.8
-
14
-
-
27744563110
-
Pathogenesis, clinical features, and neurological outcome of cerebral malaria
-
Idro R., Jenkins N.E., Newton C.R. Pathogenesis, clinical features, and neurological outcome of cerebral malaria. Lancet Neurol. 2005, 4:827-840.
-
(2005)
Lancet Neurol.
, vol.4
, pp. 827-840
-
-
Idro, R.1
Jenkins, N.E.2
Newton, C.R.3
-
15
-
-
84984541576
-
C-Jun N-terminal kinase 3 deficiency protects neurons from axotomy-induced death in vivo through mechanisms independent of c-Jun phosphorylation
-
Keramaris E., Vanderluit J.L., Bahadori M., Mousavi K., Davis R.J., Flavell R., Slack R.S., Park D.S. c-Jun N-terminal kinase 3 deficiency protects neurons from axotomy-induced death in vivo through mechanisms independent of c-Jun phosphorylation. J. Biol. Chem. 2005, 280:1132-1141.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 1132-1141
-
-
Keramaris, E.1
Vanderluit, J.L.2
Bahadori, M.3
Mousavi, K.4
Davis, R.J.5
Flavell, R.6
Slack, R.S.7
Park, D.S.8
-
16
-
-
10744229507
-
A critical role of neural-specific JNK3 for ischemic apoptosis
-
Kuan C.Y., Whitmarsh A.J., Yang D.D., Liao G., Schloemer A.J., Dong C., Bao J., Banasiak K.J., Haddad G.G., Flavell R.A., Davis R.J., Rakic P. A critical role of neural-specific JNK3 for ischemic apoptosis. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:15184-15189.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 15184-15189
-
-
Kuan, C.Y.1
Whitmarsh, A.J.2
Yang, D.D.3
Liao, G.4
Schloemer, A.J.5
Dong, C.6
Bao, J.7
Banasiak, K.J.8
Haddad, G.G.9
Flavell, R.A.10
Davis, R.J.11
Rakic, P.12
-
17
-
-
0037031527
-
Mitochondrial anomalies are associated with the induction of intrinsic cell death proteins-Bcl(2), Bax, cytochrome-c and p53 in mice brain during experimental fatal murine cerebral malaria
-
Kumar K.A., Babu P.P. Mitochondrial anomalies are associated with the induction of intrinsic cell death proteins-Bcl(2), Bax, cytochrome-c and p53 in mice brain during experimental fatal murine cerebral malaria. Neurosci. Lett. 2002, 329:319-323.
-
(2002)
Neurosci. Lett.
, vol.329
, pp. 319-323
-
-
Kumar, K.A.1
Babu, P.P.2
-
18
-
-
34548555890
-
Apoptosis in experimental cerebral malaria: spatial profile of cleaved caspase-3 and ultrastructural alterations in different disease stages
-
Lackner P., Burger C., Pfaller K., Heussler V., Helbok R., Morandell M., Broessner G., Tannich E., Schmutzhard E., Beer R. Apoptosis in experimental cerebral malaria: spatial profile of cleaved caspase-3 and ultrastructural alterations in different disease stages. Neuropathol. Appl. Neurobiol. 2007, 33:560-571.
-
(2007)
Neuropathol. Appl. Neurobiol.
, vol.33
, pp. 560-571
-
-
Lackner, P.1
Burger, C.2
Pfaller, K.3
Heussler, V.4
Helbok, R.5
Morandell, M.6
Broessner, G.7
Tannich, E.8
Schmutzhard, E.9
Beer, R.10
-
19
-
-
0037418238
-
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
-
Lei K., Davis R.J. JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:2432-2437.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 2432-2437
-
-
Lei, K.1
Davis, R.J.2
-
20
-
-
16844387124
-
Role of JNK activation in apoptosis: a double-edged sword
-
Liu J., Lin A. Role of JNK activation in apoptosis: a double-edged sword. Cell Res. 2005, 15:36-42.
-
(2005)
Cell Res.
, vol.15
, pp. 36-42
-
-
Liu, J.1
Lin, A.2
-
21
-
-
33750354369
-
Disruption of JNK2 decreases the cytokine response to Plasmodium falciparum glycosylphosphatidylinositol in vitro and confers protection in a cerebral malaria model
-
Lu Z., Serghides L., Patel S.N., Degousee N., Rubin B.B., Krishnegowda G., Gowda D.C., Karin M., Kain K.C. Disruption of JNK2 decreases the cytokine response to Plasmodium falciparum glycosylphosphatidylinositol in vitro and confers protection in a cerebral malaria model. J. Immunol. 2006, 177:6344-6352.
-
(2006)
J. Immunol.
, vol.177
, pp. 6344-6352
-
-
Lu, Z.1
Serghides, L.2
Patel, S.N.3
Degousee, N.4
Rubin, B.B.5
Krishnegowda, G.6
Gowda, D.C.7
Karin, M.8
Kain, K.C.9
-
22
-
-
0031081063
-
Early activation of microglia in the pathogenesis of fatal murine cerebral malaria
-
Medana I.M., Hunt N.H., Chan-Ling T. Early activation of microglia in the pathogenesis of fatal murine cerebral malaria. Glia 1997, 19:91-103.
-
(1997)
Glia
, vol.19
, pp. 91-103
-
-
Medana, I.M.1
Hunt, N.H.2
Chan-Ling, T.3
-
23
-
-
0028568217
-
Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK
-
Minden A., Lin A., McMahon M., Lange-Carter C., Dérijard B., Davis R.J., Johnson G.L., Karin M. Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK. Science 1994, 266:1719-1723.
-
(1994)
Science
, vol.266
, pp. 1719-1723
-
-
Minden, A.1
Lin, A.2
McMahon, M.3
Lange-Carter, C.4
Dérijard, B.5
Davis, R.J.6
Johnson, G.L.7
Karin, M.8
-
24
-
-
0037442024
-
Perforin-dependent brain-infiltrating cytotoxic CD8+ T lymphocytes mediate experimental cerebral malaria pathogenesis
-
Nitcheu J., Bonduelle O., Combadiere C., Tefit M., Seilhean D., Mazier D., Combadiere B. Perforin-dependent brain-infiltrating cytotoxic CD8+ T lymphocytes mediate experimental cerebral malaria pathogenesis. J. Immunol. 2003, 170:2221-2228.
-
(2003)
J. Immunol.
, vol.170
, pp. 2221-2228
-
-
Nitcheu, J.1
Bonduelle, O.2
Combadiere, C.3
Tefit, M.4
Seilhean, D.5
Mazier, D.6
Combadiere, B.7
-
25
-
-
63149175770
-
Blockade of the translocation and activation of c-Jun N-terminal kinase 3 (JNK3) attenuates dopaminergic neuronal damage in mouse model of Parkinson's disease
-
Pan J., Xiao Q., Sheng C.Y., Hong Z., Yang H.Q., Wang G., Ding J.Q., Chen S.D. Blockade of the translocation and activation of c-Jun N-terminal kinase 3 (JNK3) attenuates dopaminergic neuronal damage in mouse model of Parkinson's disease. Neurochem. Int. 2009, 54:418-425.
-
(2009)
Neurochem. Int.
, vol.54
, pp. 418-425
-
-
Pan, J.1
Xiao, Q.2
Sheng, C.Y.3
Hong, Z.4
Yang, H.Q.5
Wang, G.6
Ding, J.Q.7
Chen, S.D.8
-
26
-
-
0642373872
-
An ultrastructural study of the brain in fatal Plasmodium falciparum malaria
-
Pongponratn E., Turner G.D., Day N.P., Phu N.H., Simpson J.A., Stepniewska K., Mai N.T., Viriyavejakul P., Looareesuwan S., Hien T.T., Ferguson D.J., White N.J. An ultrastructural study of the brain in fatal Plasmodium falciparum malaria. Am. J. Trop. Med. Hyg. 2003, 69:345-359.
-
(2003)
Am. J. Trop. Med. Hyg.
, vol.69
, pp. 345-359
-
-
Pongponratn, E.1
Turner, G.D.2
Day, N.P.3
Phu, N.H.4
Simpson, J.A.5
Stepniewska, K.6
Mai, N.T.7
Viriyavejakul, P.8
Looareesuwan, S.9
Hien, T.T.10
Ferguson, D.J.11
White, N.J.12
-
27
-
-
33646584526
-
Perforin mediated apoptosis of cerebral microvascular endothelial cells during experimental cerebral malaria
-
Potter S., Chan-Ling T., Ball H.J., Mansour H., Mitchell A., Maluish L., Hunt N.H. Perforin mediated apoptosis of cerebral microvascular endothelial cells during experimental cerebral malaria. Int. J. Parasitol. 2006, 36:485-496.
-
(2006)
Int. J. Parasitol.
, vol.36
, pp. 485-496
-
-
Potter, S.1
Chan-Ling, T.2
Ball, H.J.3
Mansour, H.4
Mitchell, A.5
Maluish, L.6
Hunt, N.H.7
-
28
-
-
33646468915
-
Pathogenic T cells in cerebral malaria
-
Rénia L., Potter S.M., Mauduit M., Rosa D.S., Kayibanda M., Deschemin J.C., Snounou G., Grüner A.C. Pathogenic T cells in cerebral malaria. Int. J. Parasitol. 2006, 36:547-554.
-
(2006)
Int. J. Parasitol.
, vol.36
, pp. 547-554
-
-
Rénia, L.1
Potter, S.M.2
Mauduit, M.3
Rosa, D.S.4
Kayibanda, M.5
Deschemin, J.C.6
Snounou, G.7
Grüner, A.C.8
-
29
-
-
0034714392
-
Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration
-
Schmued L.C., Hopkins K.J. Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration. Brain Res. 2000, 874:123-130.
-
(2000)
Brain Res.
, vol.874
, pp. 123-130
-
-
Schmued, L.C.1
Hopkins, K.J.2
-
30
-
-
0036098552
-
AP-1 as a regulator of cell life and death
-
Shaulian E., Karin M. AP-1 as a regulator of cell life and death. Nat. Cell. Biol. 2002, 4:131-136.
-
(2002)
Nat. Cell. Biol.
, vol.4
, pp. 131-136
-
-
Shaulian, E.1
Karin, M.2
-
31
-
-
29244461405
-
Activation of calpains, calpastatin and spectrin cleavage in the brain during the pathology of fatal murine cerebral malaria
-
Shukla M., Rajgopal Y., Babu P.P. Activation of calpains, calpastatin and spectrin cleavage in the brain during the pathology of fatal murine cerebral malaria. Neurochem. Int. 2006, 48:108-113.
-
(2006)
Neurochem. Int.
, vol.48
, pp. 108-113
-
-
Shukla, M.1
Rajgopal, Y.2
Babu, P.P.3
-
32
-
-
33746263669
-
Neuronal apoptosis, metallothionein expression and proinflammatory responses during cerebral malaria in mice
-
Wiese L., Kurtzhals J.A., Penkowa M. Neuronal apoptosis, metallothionein expression and proinflammatory responses during cerebral malaria in mice. Exp. Neurol. 2006, 200:216-226.
-
(2006)
Exp. Neurol.
, vol.200
, pp. 216-226
-
-
Wiese, L.1
Kurtzhals, J.A.2
Penkowa, M.3
-
33
-
-
0032894571
-
Gamma delta T-cell function in pathogenesis of cerebral malaria in mice infected with Plasmodium berghei ANKA
-
Yañez D.M., Batchelder J., van der Heyde H.C., Manning D.D., Weidanz W.P. Gamma delta T-cell function in pathogenesis of cerebral malaria in mice infected with Plasmodium berghei ANKA. Infect. Immun. 1999, 67:446-448.
-
(1999)
Infect. Immun.
, vol.67
, pp. 446-448
-
-
Yañez, D.M.1
Batchelder, J.2
van der Heyde, H.C.3
Manning, D.D.4
Weidanz, W.P.5
-
34
-
-
0030780804
-
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene
-
Yang D.D., Kuan C.Y., Whitmarsh A.J., Rincón M., Zheng T.S., Davis R.J., Rakic P., Flavell R.A. Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature 1997, 389:865-870.
-
(1997)
Nature
, vol.389
, pp. 865-870
-
-
Yang, D.D.1
Kuan, C.Y.2
Whitmarsh, A.J.3
Rincón, M.4
Zheng, T.S.5
Davis, R.J.6
Rakic, P.7
Flavell, R.A.8
|