AS601245 (1,3-Benzothiazol-2-yl (2-{[2-(3-pyridinyl) ethyl] amino}-4 pyrimidinyl) Acetonitrile): A c-Jun NH2-terminal protein kinase inhibitor with neuroprotective properties

Journal of Pharmacology and Experimental Therapeutics

Volumn 310, Issue 1, 2004, Pages 25-32

  Carboni, Sonia ^a   Hiver, Agnes ^a   Szyndralewiez, Cedric ^a   Gaillard, Pascale ^a   Gotteland, Jean Pierre ^a   Vitte, Pierre Alain ^a  

^a SERONO PHARMACEUTICAL RES INSTITUTE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 BENZOTHIAZOL 2 YL [2 [[2 (3 PYRIDINYL)ETHYL]AMINO] 4 PYRIMIDINYL]ACETONITRILE; CYTOKINE; DEXAMETHASONE; DIZOCILPINE; NEUROPROTECTIVE AGENT; STEROID; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; GERBIL; HIPPOCAMPUS; HISTOLOGY; IMMUNE RESPONSE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ACETONITRILES; ANIMALS; BENZOTHIAZOLES; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; GERBILLINAE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C3H; MITOGEN-ACTIVATED PROTEIN KINASES; NEUROPROTECTIVE AGENTS; PHOSPHORYLATION; RATS; RATS, WISTAR; THIAZOLES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 3042694681     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.064246     Document Type: Article

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