HIG1, a novel regulator of mitochondrial γ-secretase, maintains normal mitochondrial function

FASEB Journal

Volumn 26, Issue 6, 2012, Pages 2306-2317

  Hayashi, Hiroki ^a   Nakagami, Hironori ^a,b   Takeichi, Makiko ^a   Shimamura, Munehisa ^b   Koibuchi, Nobutaka ^c   Oiki, Eiji ^b   Sato, Naoyuki ^b   Koriyama, Hiroshi ^b   Mori, Masaki ^a   Araujo, Rodriguez Gerardo ^a   Maeda, Akito ^b   Morishita, Ryuichi ^b   Tamai, Katsuto ^a   Kaneda, Yasufumi ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Alzheimer's disease; Hypoxia; Intracellular A ; Neuron; Oxidative stress

Indexed keywords

AMYLOID BETA PROTEIN; ANTERIOR PHARYNX DEFECTIVE 1 PROTEIN; GAMMA SECRETASE; HYPOXIA INDUCIBLE GENE 1 DOMAIN MEMBER 1A; NICASTRIN; PRESENILIN 1; PRESENILIN ENHANCER 2; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BRAIN; CELL STRAIN HEK293; CELLULAR DISTRIBUTION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NEUROBLASTOMA CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION;

AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BRAIN; CELL HYPOXIA; CELL LINE, TUMOR; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; LIVER; MALE; MICE; MICRORNAS; MITOCHONDRIAL MEMBRANES; MYOCARDIUM; NEOPLASM PROTEINS; RATS; RATS, WISTAR;

EID: 84861761931     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-196063     Document Type: Article

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