Fermented papaya preparation attenuates β-amyloid precursor protein: β-amyloid-mediated copper neurotoxicity in β-amyloid precursor protein and β-amyloid precursor protein Swedish mutation overexpressing SH-SY5Y cells

Neuroscience

Volumn 143, Issue 1, 2006, Pages 63-72

  Zhang, J ^a,b   Mori, A ^c   Chen, Q ^d   Zhao, B ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

^d SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

amyloid; Alzheimer's disease; copper; papaya

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CALCIUM; COPPER; FREE RADICAL; HYDROXYL RADICAL; NITRIC OXIDE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL VIABILITY; FERMENTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MUTATION; NEUROTOXICITY; PAPAYA; PRIORITY JOURNAL;

AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANALYSIS OF VARIANCE; APOPTOSIS; BLOTTING, WESTERN; CALCIUM; CARICA; CELL LINE, TUMOR; CELL SURVIVAL; COPPER; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HUMANS; MUTATION; NEUROBLASTOMA; NITRIC OXIDE SYNTHASE; PLANT PROTEINS; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TRANSFECTION;

EID: 33750503794     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2006.07.023     Document Type: Article

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