FHL-2 suppresses VEGF-induced phosphatidylinositol 3-kinase/Akt activation via interaction with sphingosine kinase-1

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 29, Issue 6, 2009, Pages 909-914

  Hayashi, Hiroki ^a   Nakagami, Hironori ^a,c   Takami, Yoichi ^a   Koriyama, Hiroshi ^a   Mori, Masaki ^a   Tamai, Katsuto ^a   Sun, Jianxin ^b   Nagao, Kaori ^a   Morishita, Ryuichi ^a   Kaneda, Yasufumi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Akt pathway; Endothelial cells; FHL 2; Sphingosine kinase 1; VEGF

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; FOUR AND A HALF LIM ONLY PROTEIN 2; LIM PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; SPHINGOSINE KINASE 1; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; DRUG DERIVATIVE; FHL2 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; LYSOPHOSPHOLIPID; MUSCLE PROTEIN; PHOSPHOTRANSFERASE; RECOMBINANT PROTEIN; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1-PHOSPHATE; SPHINGOSINE KINASE; TRANSCRIPTION FACTOR; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ANIMAL CELL; ANTIANGIOGENIC ACTIVITY; ARTICLE; CELL MIGRATION; EMBRYO; ENDOTHELIUM CELL; ENZYME ACTIVATION; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN SITU HYBRIDIZATION; INHIBITION KINETICS; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; XENOPUS; ANGIOGENESIS; ANIMAL; CATTLE; CELL CULTURE; CELL MOTION; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; PHOSPHORYLATION; PRENATAL DEVELOPMENT; RNA INTERFERENCE; TIME; XENOPUS LAEVIS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CATTLE; CELL MOVEMENT; CELLS, CULTURED; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; HUMANS; LYSOPHOSPHOLIPIDS; MUSCLE PROTEINS; NEOVASCULARIZATION, PHYSIOLOGIC; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SPHINGOSINE; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; XENOPUS LAEVIS;

EID: 66349112011     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.108.178541     Document Type: Article

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