Selective inhibitors of bacterial phosphopantothenoylcysteine synthetase

Journal of the American Chemical Society

Volumn 131, Issue 45, 2009, Pages 16340-16341

  Patrone, James D ^a   Yao, Jiangwei ^a   Scott, Nicole E ^a   Dotson, Garry D ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYMES; CYTIDINE; HUMAN ENZYMES; IN-VITRO; KINETIC CHARACTERIZATION; L-CYSTEINE; NUCLEOBASES; PHOSPHODIESTERS; POTENT INHIBITOR; SELECTIVE INHIBITORS; SYNTHETASES; TIGHT BINDING; TRIPHOSPHATE;

BINDING ENERGY; BINDING SITES; ENZYMES; SYNTHESIS (CHEMICAL);

BACTERIOLOGY;

ACID ANHYDRIDE; BACTERIAL ENZYME; ENZYME INHIBITOR; NUCLEIC ACID BASE; PHOSPHOPANTOTHENOYL CYTIDYLATE; PHOSPHOPANTOTHENOYLCYSTEINE SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING KINETICS; BINDING SITE; NONHUMAN;

DRUG DESIGN; ENTEROCOCCUS FAECALIS; ENZYME INHIBITORS; ESCHERICHIA COLI; HUMANS; MOLECULAR CONFORMATION; PEPTIDE SYNTHASES; PHOSPHORIC ACID ESTERS; STEREOISOMERISM; STREPTOCOCCUS PNEUMONIAE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 70450169450     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja906537f     Document Type: Article

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