Structural basis for substrate binding and the catalytic mechanism of type III pantothenate kinase

Biochemistry

Volumn 47, Issue 5, 2008, Pages 1369-1380

  Yang, Kun ^a   Strauss, Erick ^b   Huerta, Carlos ^a   Zhang, Hong ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMATIC PROPERTIES; SUBSTRATE BINDING;

BINDING SITES; BIOSYNTHESIS; ESCHERICHIA COLI; GENE ENCODING; METABOLITES; THERMODYNAMIC PROPERTIES;

ENZYME KINETICS;

ACETATE KINASE; ACTIN; ANTIBIOTIC AGENT; ANTIMETABOLITE; BACTERIAL PROTEIN; HEAT SHOCK PROTEIN 70; PANTOTHENAMIDE DERIVATIVE; PANTOTHENATE KINASE; PANTOTHENATE KINASE 3; PANTOTHENATE KINASE 3 INHIBITOR; PROTEIN COAA; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BINDING SITE; CATALYSIS; COAX GENE; CRYSTAL STRUCTURE; DRUG DESIGN; ENZYME BINDING; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; EUKARYOTE; GENE; GROWTH INHIBITION; IN VIVO STUDY; INHIBITION KINETICS; ISOTHERMAL TITRATION CALORIMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE; STAPHYLOCOCCUS AUREUS; THERMODYNAMICS; THERMOTOGA MARITIMA;

ADENOSINE DIPHOSPHATE; ADENYLYL IMIDODIPHOSPHATE; AMINO ACID SEQUENCE; BINDING SITES; CALORIMETRY; CATALYSIS; CRYSTALLIZATION; HELICOBACTER PYLORI; KINETICS; MOLECULAR SEQUENCE DATA; PANTOTHENIC ACID; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); THERMODYNAMICS; THERMOTOGA MARITIMA;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; EUKARYOTA; THERMOTOGA MARITIMA;

EID: 38849134895     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi7018578     Document Type: Article

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