Phosphopantothenoylcysteine Synthetase from Escherichia coli. Identification and characterization of the last unidentified coenzyme A biosynthetic enzyme in bacteria

Journal of Biological Chemistry

Volumn 276, Issue 17, 2001, Pages 13513-13516

  Strauss, Erick ^b   Kinsland, Cynthia ^b   Ge, Ying ^b   McLafferty, Fred W ^b   Begley, Tadhg P ^a  

^a Cornell University ^*  (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CATALYSTS; COENZYMES; ESCHERICHIA COLI; GENES;

NUCLEOSIDE;

BIOCHEMISTRY;

BACTERIAL ENZYME; CARBON 14; CARBOXYLYASE; COENZYME A; CYSTEINE; CYTIDINE PHOSPHATE; DFP PROTEIN; PHOSPHOPANTOTHENOYLCYSTEINE SYNTHETASE; PROTEIN; RECOMBINANT PROTEIN; SYNTHETASE; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; CYTIDINE TRIPHOSPHATE; DRUG DERIVATIVE; PANTOTHENIC ACID; PANTOTHENYLCYSTEINE 4' PHOSPHATE; PANTOTHENYLCYSTEINE 4'-PHOSPHATE; PEPTIDE SYNTHASE; PHOSPHOPANTOTHENOYL CYSTEINE DECARBOXYLASE; PHOSPHOPANTOTHENOYL-CYSTEINE DECARBOXYLASE; PHOSPHOPANTOTHENOYL-CYSTEINE SYNTHETASE; RIBOFLAVIN DERIVATIVE;

ARTICLE; BIOSYNTHESIS; DFP GENE; ENZYME PURIFICATION; ESCHERICHIA COLI; GENE; GENE OVEREXPRESSION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; CHEMICAL MODEL; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; ENZYMOLOGY; GENETICS; KINETICS; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS; ULTRAVIOLET RADIATION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

ADENOSINE TRIPHOSPHATE; CARBOXY-LYASES; CLONING, MOLECULAR; COENZYME A; CYSTEINE; CYTIDINE MONOPHOSPHATE; CYTIDINE TRIPHOSPHATE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; FLAVINS; KINETICS; MODELS, CHEMICAL; PANTOTHENIC ACID; PEPTIDE SYNTHASES; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; ULTRAVIOLET RAYS;

EID: 0035957936     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C100033200     Document Type: Article

References (19)

1. Lee, C. H., and Chen, A. F. (1982) in The Pyridine Nucleotide Coenzymes (Everse, J., Anderson, B., and You, K., eds) p. 189, Academic Press, Inc., New York
2. Begley, T. P., Kinsland, C., and Strauss, E. (2001) in Vitamins and Hormones (Litwack, G., and Begley, T. P., eds) Vol 61, pp. 157-171, Academic Press, Inc., New York
3. Geerlof, A., Lewendon, A., and Shaw, W. V. (1999) J. Biol. Chem. 274, 27105-27111
4. Yang, H., and Abeles, R. H. (1987) Biochemistry 26, 4076-4081
5. Spitzer, E. D., and Weiss, B. (1985) J. Bacteriol. 164, 994-1003
6. Spitzer, E. D., Jimenez-Billini, H. E., and Weiss, B. (1988) J. Bacteriol. 170, 872-876
7. Kupke, T., Uebele, M., Schmid, D., Jung, G., Blaesse, M., and Steinbacher, S. (2000) J. Biol. Chem. 275, 31838-31846
8. Martin, D. P., Bibart, R. T., and Drueckhammer, D. G. (1994) J. Am. Chem. Soc. 116, 4660-4668
9. Beu, S. C., Senko, M. W., Quinn, J. P., Wampler, F. M., and McLafferty, F. W. (1993) J. Am. Soc. Mass Spectrom. 4, 557-565
10. Wilm, M., and Mann, M. (1996) Anal. Chem. 68, 1-8
11. Loo, J. A., and Smith, R. D. (1988) Rapid Commun. Mass Spectrom. 2, 207-221
12. Little, D. P., Speir, J. P., Senko, M. W., O'Connor, P. B., and McLafferty, F. W. (1994) Anal. Chem. 66, 2809-2815
13. Brown, G. M. (1959) J. Biol. Chem. 234, 370-378
14. Altschul, S. F., Gish, W., Miller, W., Myers, E. W., and Lipman, D. J. (1990) J. Mol. Biol. 215, 403-410
15. Weber, C. H., Park, Y. S., Sanker, S., Kent, C., and Ludwig, M. L. (1999) Structure (Lond.) 7, 1113-1124
16. Abiko, Y. (1970) Methods Enzymol. 18A, 350-354
17. Scandurra, R., Barboni, E., Granata, F., Pensa, B., and Costa, M. (1974) Eur. J. Biochem. 49, 1-9
18. Abiko, Y. (1970) Methods Enzymol. 18A, 354-358
19. Scandurra, R., Politi, L., Santoro, L., and Consalvi, V. (1987) FEBS Lett. 212, 79-82