Presenilin-2 regulates the degradation of RBP-Jk protein through p38 mitogen-activated protein kinase

Journal of Cell Science

Volumn 125, Issue 5, 2012, Pages 1296-1308

  Kim, Su Man ^a   Kim, Mi Yeon ^a   Ann, Eun Jung ^a   Mo, Jung Soon ^a   Yoon, Ji Hye ^a   Park, Hee Sae ^a  

^a Chonnam National University   (South Korea)

Author keywords

Lysosome; P38 MAPK; Presenilin 2; Proteasome; Protein degradation; Rbp Jk

Indexed keywords

BETA ACTIN; BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; NOTCH1 RECEPTOR; PRESENILIN 2; PROTEASOME INHIBITOR; RBP JK PROTEIN; THREONINE; UNCLASSIFIED DRUG;

ARTICLE; CELL LEVEL; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; UBIQUITINATION;

ACETYLCYSTEINE; AMMONIUM CHLORIDE; CELL LINE; CHLOROQUINE; CYSTEINE PROTEINASE INHIBITORS; GENE KNOCKOUT TECHNIQUES; HEK293 CELLS; HUMANS; IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE-BINDING PROTEIN; LEUPEPTINS; LYSOSOMES; MAP KINASE SIGNALING SYSTEM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PRESENILIN-1; PRESENILIN-2; PROTEASOME INHIBITORS; PROTEOLYSIS; RECEPTOR, NOTCH1; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; UBIQUITINATION;

EID: 84861380432     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.095984     Document Type: Article

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