A subset of Notch functions during Drosophila eye development require Su(H) and the E(spl) gene complex

Development

Volumn 125, Issue 15, 1998, Pages 2893-2900

  Ligoxygakis, Petros ^a   Yu, Sung Yun ^b   Delidakis, Christos ^a   Baker, Nicholas E ^b  

^a INSTITUTE OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY   (Greece)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Atonal; Drosophila eye; Enhancer of split; Notch; Suppressor of hairless

Indexed keywords

ANIMAL CELL; ARTICLE; AUTOREGULATION; CONTROLLED STUDY; DROSOPHILA; EMBRYO; EYE DEVELOPMENT; GENE EXPRESSION; GENE FUNCTION; IMAGINAL DISC; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BODY PATTERNING; CALCIUM-BINDING PROTEINS; CELL DIFFERENTIATION; CLONE CELLS; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; EYE; GENES, INSECT; HELIX-LOOP-HELIX MOTIFS; INSECT PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; MEMBRANE PROTEINS; MUTATION; NERVE TISSUE PROTEINS; PHOTORECEPTORS, INVERTEBRATE; RECEPTORS, NOTCH; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 0031684531     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Artavanis-Tsakonas, S., Matsuno, K. and Fortini, M. E. (1995). Notch signalling. Science 268, 225-232.
2. Bailey, A. M. and Posakony, J. W. (1995). Suppressor of Hairless directly activates transcription of Enhancer of split Complex genes in response to Notch receptor activity. Genes Dev. 9, 2609-2622.
3. Baker, N. E. and Yu, S. (1997). Proneural function of neurogenic genes in the developing Drosophila eye. Curr. Biol. 7, 122-132.
4. Baker, N. E., Yu, S. and Han, D. (1996). Evolution of proneural atonal expression during distinct regulatory phases in the developing Drosophila eye. Curr. Biol. 6, 1290-1301.
5. Baker, N. E. and Zitron, A. E. (1995). Drosophila eye development: Notch and Delta amplify a neurogenic pattern conferred on the morphogenetic furrow by scabrous. Mech. Dev. 49, 173-189.
6. D mutation of Drosophila melanogaster. Roux's Arch. Dev. Biol. 198, 286-294.
7. Coffman, C. R., Skoglund, P., Harris, W. A. and Kintner, C. R. (1993). Expression of an extracellular deletion of Xotch diverts cellfate in Xenopus embryos. Cell 73, 659-671.
8. Couso, J. P., Knust, E. and Martinez Arias, A. (1995). Serrate and wingless cooperate to induce vestigial gene expression and wing formationm in Drosophila. Curr. Biol. 5, 1437-1448.
9. Dawson, S. R., Turner, D. L., Weintraub, H. and Parkhurst, S. M. (1995). Specificity for the Hairy/Enhancer of split basic helix-loop-helix (bHLH) proteins maps outside the bHLH domain and suggests two separable modes of transcriptional repression. Mol. Cell. Biol. 15, 6923-6931.
10. de Celis, J. F., de Celis, J., Ligoxygakis, p., Preiss, A., Delidakis, C. and Bray, S. (1996a). Functional relationships between Notch, Su(H) and the bHLH genes of the E(spl) complex: the E(spl) genes mediate only a subset of Notch activities during imaginai development. Development 122, 2719-2728.
11. de Celis, J. F., Garcia-Bellido, A. and Bray, S. J. (1996b). Activation and function of Notch at the dorsal-ventral boundary of the wing imaginal disc. Development 122, 359-369.
12. Delidakis, C. and Artavanis-Tsakonas, S. (1992). The Enhancer of split [E(Spl)] locus of Drosophila encodes seven independent helix-loop-helix proteins. Proc. Nat. Acad. Sci. USA 89, 8731-8735.
13. Doherty, D., Feger, G., Younger-Sheperd, S., Jan, L. Y. and Jan, Y. N. (1996). Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation. Genes Dev. 10, 421-434.
14. Dokucu, M. E., Zipursky, S. L. and Cagan, R. L. (1996). Atonal, Rough and the resolution of proneural clusters in the developing Drosophila retina. Development 122, 4139-4147.
15. Eastman, D. S., Slee, R., Skoufos, E., Bangalore, L., Bray, S. and Delidakis, C. (1997). Activated Notch regulation of Enhancer of split mγ and mδ expression is mediated by Suppressor of Hairless. Mol. Cell. Biol. 17, 5620-5628.
16. Ellis, M. C., Weber, U., Wiersdorff, V. and Mlodzik, M. (1994). Confrontation of scabrous expressing and non-expressing cells is essential for normal ommatidial spacing in the Drosophila eye. Development 120, 1959-1969.
17. Fisher, A. L., Ohsako, S. and Caudy, M. (1996). The WRPW motif of the Hairy-related basic Helix-Loop-Helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain. Mol. Cell. Biol. 16, 2670-2677.
18. Fortini, M. E. and Artavanis-Tsakonas, S. (1994). The Suppressor of Hairless protein participates in Notch signaling. Cell 79, 273-282.
19. Fortini, M. E., Rebay, I., Caron, L. A. and Artavanis-Tsakonas, S. (1993). An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye. Nature 365, 555-557.
20. Giebel, B. and Campos-Ortega, J. A. (1997). Functional dissection of the Drosophila Enhancer-of-split protein, a suppressor of neurogenesis. Proc. Nat. Acad. Sci. USA 94, 6250-6254.
21. Heitzler, P., Bourois, M., Ruel, L., Carteret, C. and Simpson, P. (1996). Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila. Development 122, 161-171.
22. Jarman, A. P., Grell, E. H., Ackerman, L., Jan, L. Y. and Jan, Y. N. (1994). atonal is the proneural gene for Drosophila photoreceptors. Nature 369, 398-400.
23. Jarriault, S., Brou, C., Logeat, F., Schroeter, E. H., Kopan, R. and Israel, A. (1995). Signalling downstream of activated mammalian Notch. Nature 377, 355-358.
24. Jennings, B., Preiss, A., Delidakis, C. and Bray, S. (1994). The Notch signalling pathway is required for Enhancer of split bHLH protein expression during neurogenesis in the Drosophila embryo. Development 120, 3537-3548.
25. Kato, H., Taniguchi, Y., Kurooka, H., Minoguchi, S., Sakai, T., Nomura-Okazaki, S., Tamura, K. and T., H. (1997). Involvement of RBP-J in biological functions of mouse Notch 1 and its derivatives. Development 124, 4133-4141.
26. Kim, J., Irvine, K. D. and Carroll, S. B. (1995). Cell recognition, signal induction and symmetrical gene activation at the dorsal-ventral boundary of the developing Drosophila wing. Cell 82, 795-802.
27. Kim, J., Sebring, A., Esch, J. J., Kraus, M. E., Vorwerk, M., Magee, J. and Carroll, S. B. (1996). Integration of positional signals and regulation of wing formation and identity by Drosophila vestigial gene. Nature 382, 133-138.
28. Kimmel, B. E., Heberlein, U. and Rubin, G. M. (1990). The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype. Genes Dev. 4, 712-727.
29. Knust, E., Schrons, H., Grawe, F. and Campos-Ortaga, J. A. (1992). Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins. Genetics 132, 505-518.
30. Kramer, H., Cagan, R. L. and Zipursky, S. L. (1991). Interaction of bride of sevenless membrane-bound ligand and the sevenless tyrosine-kinase receptor. Nature 352, 207-212.
31. Lambie, E.J. and Kimble, J. (1991). Two homologous regulatory genes, lin-12 and glp-1, have overlapping functions. Development 112, 231-240.
32. Lecourtois, M. and Schweisguth, F. (1995). The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the Enhancer of split Complex genes triggered by Notch signaling. Genes Dev. 9, 2598-2608.
33. Lee, E.-C., Hu, X., Yu, S. Y. and Baker, N. E. (1996). The scabrous gene encodes a secreted glycoprotein dimer and regulates proneural development in Drosophila eyes. Mol. Cell. Biol. 16, 1179-1188.
34. Lewis, J. (1996). Neurogenic genes and vertebrate neurogenesis. Curr. Opin. Neurobiol. 6, 3-10.
35. Lieber, T., Kidd, S., Alcamo, E., Corbin, V. and Young, M. W. (1993). Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function of Notch in nuclei. Genes Dev. 7, 1949-1965.
36. Maier, D., Marte, B. M., Schafer, W., Yu, Y. and Preiss, A. (1993). Drosophila evolution challenges postulated redundancy in the E(spl) gene complex. Proc. Nat. Acad. Sci. USA 90, 5464-5468.
37. Matsuno, K., Go, M. J., Eastman, D. S. and Artavanis-Tsakonas, S. (1997). Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements. Development 124, 4265-4273.
38. Micchelli, C. A., Rulifson, E. J. and Blair, S. S. (1997). The function and regulation of cut expression on the wing margin of Drosophila: Notch, Wingless and a dominant negative role for Delta and Serrate. Development 124, 1485-1495.
39. Nakao, K. and Campos-Ortega, J. A. (1996). Persistent expression of genes of the Enhancer of split complex suppresses neural development in Drosophila. Neuron 16, 275-286.
40. Oellers, N., Dehio, M. and Knust, E. (1994). bHLH genes encoded by the Enhancer of split complex of Drosophila negatively interfere with transcriptional activation mediated by proneural genes. Mol. Gen. Genet. 244, 465-473.
41. Panin, V. M., Papayannopoulos, V., Wilson, R. and Irvine, K. D. (1997). Fringe modulates Notch-ligand interactions. Nature 387, 908-912.
42. Paroush, Z., Finley, R. L. J., Kidd, T., Wainwright, S. M., Ingham, P. W., Brent, R. and Ish-Horowicz, D. (1994). Groucho is required for Drosophila neurogenesis, segmentation and sex determination and interacts directly with hairy-related bHLH proteins. Cell 79, 805-815.
43. Roehl, H. and Kimble, J. (1993). Control of cell fate in C. elegant by a GLP-1 peptide consisting primarily of ankyrin repeats. Nature 364, 632-635.
44. Roehl, H., Rosenberg, M., Blelloch, R. and Kimble, J. (1996). Roles of the RAM and ANK domains in signalling by the C. elegans GLP-1 receptor. EMBO J. 15, 7002-7012.
45. Schrons, H., Knust, E. and Campos-Ortega, J. A. (1992). The Enhancer of split Complex and adjacent genes in the 96F region of Drosophila melanogaster are required for segregation of neural and epidermal progenitor cells. Genetics 132, 481-503.
46. Schweisguth, F. (1995). Suppressor of Hairless is required for signal reception during lateral inhibition in the Drosophila pupal notum. Development 121, 1875-1884.
47. Shawber, C., Nofziger, D., Hsieh, J. J.-D., Lindsell, C., Bögler, O., Hayward, D. and Weinmaster, G. (1996). Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway. Development 122, 3765-3773.
48. Struhl, G., Fitzgerald, K. and Greenwald, I. (1993). Intrinsic activity of the lin-12 and Notch intracellular domains in vivo. Cell 74, 331-345.
49. Sun, X. and Artavanis-Tsakonas, S. (1996). The intracellular deletions of DELTA and SERRATE define dominant negative forms of the Drosophila Notch ligands. Development 122, 2465-2474.
50. Tamura, K., aniguchi, Y., Minoguchi, S., Sakai, T., Tun, T., Furukawa, T. and Honjo, T. (1995). Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-Jk/Su(H). Curr. Biol. 5, 1416-1423.
51. The, I., Hannigan, G. E., Cowley, G. S., Reginald, S., Zhong, Y., Gusella, J. F., Hariharan, I. K. and Bernards, A. (1997). Rescue of a Drosophila NF1 mutant phenotype by protein kinase A. Science 276, 791-794.
52. Tio, M. and Moses, K. (1997). The Drosophila TGFalpha homolog Spitz acts in photoreceptor recruitment in the developing retina. Development 124, 343-351.
53. Treisman, J. E., Luk, A., Rubin, G. M. and Heberlein, U. (1997). eyelid antagonizes wingless signaling during Drosophila development and has homology to the Bright family of DNA-binding proteins. Genes Dev. 11, 1949-1962.
54. Vincent, J., Girdham, C. and O'Farrell, P. (1994). A cell-autonomous, ubiquitous marker for the analysis of Drosophila genetic mosaics. Dev. Biol. 164, 328-331.
55. Wolff, T. and Ready, D. F. (1993). Pattern formation in the Drosophila retina. In The Development of Drosophila melanogaster, (ed. M. Bate and A. Martinez Arias), pp. 1277-1325: Cold Spring Harbor Laboratory Press.
56. Xu, T. and Rubin, G. M. (1993). Analysis of genetic mosaics in the developing and adult Drosophila tissues. Development 117, 1223-1236.